Treatment Algorithm for Chronic Idiopathic Constipation and Constipation-Predominant Irritable Bowel Syndrome Derived from a Canadian National Survey and Needs Assessment on Choices of Therapeutic Agents

Canadian Journal of Gastroenterology and Hepatology - Tập 2017 - Trang 1-11 - 2017
Yvonne Tse1, David Armstrong2, Christopher N. Andrews3, Alain Bitton4, Brian Bressler5, John K. Marshall2, Louis W. C. Liu1
1University of Toronto, Toronto, ON, Canada
2McMaster University, Hamilton, ON, Canada
3University of Calgary, Calgary, AB, Canada
4McGill University, Montreal, QC, Canada
5University of British Columbia, Vancouver, BC, Canada

Tóm tắt

Background. Chronic idiopathic constipation (CIC) and constipation-predominant irritable bowel syndrome (IBS-C) are common functional lower gastrointestinal disorders that impair patients’ quality of life. In a national survey, we aimed to evaluate (1) Canadian physician practice patterns in the utilization of therapeutic agents listed in the new ACG and AGA guidelines; (2) physicians satisfaction with these agents for their CIC and IBS-C patients; and (3) the usefulness of these new guidelines in their clinical practice. Methods. A 9-item questionnaire was sent to 350 Canadian specialists to evaluate their clinical practice for the management of CIC and IBS-C. Results. The response rate to the survey was 16% (n=55). Almost all (96%) respondents followed a standard, stepwise approach for management while they believed that only 24% of referring physicians followed the same approach. Respondents found guanylyl cyclase C (GCC) agonist most satisfying when treating their patients. Among the 69% of respondents who were aware of published guidelines, only 50% found them helpful in prioritizing treatment choices and 69% of respondents indicated that a treatment algorithm, applicable to Canadian practice, would be valuable. Conclusion. Based on this needs assessment, a treatment algorithm was developed to provide clinical guidance in the management of IBS-C and CIC in Canada.

Từ khóa


Tài liệu tham khảo

10.1111/j.1572-0241.2004.04114.x

10.1016/j.cgh.2012.02.029

2015

10.1038/ajg.2015.67

10.1016/s0002-9270(02)04199-0

10.1016/j.clinthera.2006.10.010

10.1038/ajg.2010.200

10.1038/ajg.2014.181

10.1038/ajg.2014.187

10.1053/j.gastro.2012.10.029

10.1053/j.gastro.2014.09.001

10.1038/ajg.2012.254

10.1053/j.gastro.2010.08.041

10.1038/ajg.2012.255

10.1159/000101882

10.1007/s11605-015-3023-9

10.1111/hpb.12140

10.1136/bmj.d5283

10.1016/j.cgh.2010.06.031

10.1038/ajg.2015.153

10.1111/nmo.12520

10.1155/2011/930108

10.1155/2007/848706

10.1136/gut.2009.199653

10.1111/j.1365-2982.2009.01403.x

2016

10.1111/j.1365-2036.1995.tb00433.x

10.1111/j.1532-5415.1995.tb07203.x

10.3109/00365529709011203

10.1136/gut.9.1.84

10.1111/j.1532-5415.1978.tb01967.x

10.1002/j.1552-4604.1997.tb04264.x

1991, GEN, 45, 294

10.1007/BF02087913

10.1136/gut.46.4.522

10.1111/j.1572-0241.2007.01199.x

10.1016/s0002-9270(99)00824-2

10.1056/NEJMoa0800670

10.1111/j.1365-2036.2008.03884.x

10.1136/gut.2008.162404

1991, Geriatrics, 46, 84

10.1046/j.1365-2036.1998.00336.x

10.1038/ajg.2014.148

Thông tin
Thông tin xuất bản

Canadian Journal of Gastroenterology and Hepatology

Tập 2017

1-11

Thông tin tác giả