Trastuzumab after Adjuvant Chemotherapy in HER2-Positive Breast Cancer

New England Journal of Medicine - Tập 353 Số 16 - Trang 1659-1672 - 2005
Martine Piccart1, Marion Procter2, Brian Leyland‐Jones3, Aron Goldhirsch4, Michael Untch5, Ian Smith6, Luca Gianni7, José Baselga8, Richard H. Bell9, Christian Jackisch10, David Cameron11, Mitch Dowsett12, Carlos H. Barrios13, Günther Steger14, Chiun‐Sheng Huang15, Michael Andersson16, Moshe Inbar17, Mikhail Lichinitser18, István Láng19, Ulrike Nitz20, Hiroji Iwata21, Christoph Thomssen22, Caroline Lohrisch23, Sandra M. Swain24, Josef Rüschoff25, T Sütö26, Victoria Greatorex26, Carol Ward26, Carolyn Straehle27, Eleanor McFadden2, Mirko Dolci28, Richard D. Gelber29,2
1Department of Medicine
2Kingussie, Scotland, the Department of Medicine, the European Institute of Oncology, Milan
3Department of Oncology, Gerald Bronfman Centre for Clinical Research in Oncology, McGill University, Montreal, the Department of Medicine, the European Institute of Oncology, Milan
4Oncology Institute of Southern Switzerland, Bellinzona, Switzerland
5Klinik für Frauenheilkunde und Geburtshilfe, Ludwig-Maximilians-Universität München, Grosshadern, Munich, Germany
6Breast Unit, Royal Marsden Hospital and the Institute of Cancer Research, London
7Struttura Complessa Oncologia Medica 1, Istituto Nazionale per lo Studie e la Cura dei Tumori, Milan
8Medical Oncology Service, Vall d'Hebron University Hospital, Barcelona;
9Andrew Love Cancer Centre, Geelong Hospital, Geelong, Australia
10Department of Gynecology, Philipps University of Marburg, Marburg, Germany
11Department of Oncology, Western General Hospital, Edinburgh
12Department of Academic Biochemistry, the Royal Marsden National Health Service Trust, London
13Hospital São Lucas, Pontifìcia Universidad Catòlica do Rio Grande do Sul School of Medicine, Porto Alegre, Brazil
14Department of Internal Medicine, Medical University of Vienna, Vienna
15Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei
16Department of Oncology, Finsen Center, Rigshospitalet University Hospital, Copenhagen
17Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
18N.N. Blokhin Cancer Research Center, Moscow
19Department of Oncology, National Institute of Oncology, Budapest, Hungary
20Frauenklinik der Heinrich Heine Universität Düsseldorf, Düsseldorf, Germany
21Department of Breast Oncology, Aichi Cancer Center, Aichi, Japan
22Klinik und Poliklinik für Gynäkologie, Universitätsklinikum Hamburg Eppendorf, Hamburg, Germany
23Department of Medical Oncology, British Columbia Cancer Agency, Vancouver Centre, Vancouver, B.C., Canada
24Swiss Cardiovascular Center, Bern, Switzerland
25Institut für Pathologie, Klinikum Kassel, Kassel, Germany
26F. Hoffmann‐La Roche, Basel, Switzerland
27Breast International Group Secretariat
28Breast European Adjuvant Study Team Data Centre, Jules Bordet Institute, Université Libre de Bruxelles, Brussels
29Department of Biostatistics and Computational Biology, Dana–Farber Cancer Institute, Boston

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