Vận chuyển các phân tử, hạt, và tế bào trong khối u đặc
Tóm tắt
▪ Tóm tắt Những tiến bộ phi thường trong sinh học phân tử và công nghệ sinh học đã dẫn đến sự phát triển của một số lượng lớn các tác nhân điều trị chống ung thư. Để tiếp cận các tế bào ung thư trong một khối u, một phân tử, hạt, hoặc tế bào điều trị mang trong máu phải đi vào mạch máu của khối u và vượt qua thành mạch để vào khoảng gian bào, mà từ đó nó phải di chuyển qua. Không may, các khối u thường phát triển theo những cách cản trở những bước này. Mục tiêu của nghiên cứu trong lĩnh vực này là phân tích từng bước này một cách thực nghiệm và lý thuyết, và tích hợp thông tin thu được thành một khung lý thuyết thống nhất. Mô hình phân tích và tổng hợp này đã thúc đẩy sự hiểu biết tốt hơn về các rào cản sinh lý trong các khối u đặc và hỗ trợ trong việc phát triển các chiến lược mới nhằm khai thác và/hoặc vượt qua những rào cản này để cải thiện việc phát hiện và điều trị ung thư.
Từ khóa
Tài liệu tham khảo
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