Transient apnoea after systemic injection of GABA in the rat

P. Holzer1, K. Hagmüller2
1Institut für Experimentelle und Klinische Pharmakologie, Universität Graz, Graz, Austria
2Zoologisches Institut — Tierphysiologie, Universität Graz, Graz, Austria

Tóm tắt


Tài liệu tham khảo

Adams, P. R., Brown, D. A.: Actions of gamma-aminobutyric acid on sympathetic ganglion cells. J. Physiol. (Lond.) 250, 85–120 (1975) Curtis, D. R., Johnston, G. A. R.: Amino acid transmitters in the mammalian central nervous system. Ergebn. Physiol. 69, 97–188 (1974) Dudel, J.: Presynaptic and postsynaptic effects of inhibitory drugs on the crayfish neuromuscular junction. Pflügers Arch. ges. Physiol. 283, 104–118 (1965) Elliott, K. A. C., Hobbiger, F.: Gamma-aminobutyric acid: circulatory and respiratory effects in different species; reinvestigation of the antistrychnine action in mice. J. Physiol. (Lond.) 146, 70–84 (1959) Enna, S. J., Snyder, S. H.: Influences of ions, enzymes, and detergents on gamma-aminobutyric acid-receptor binding in synaptic membranes of rat brain. Mol. Pharmacol. 13, 442–453 (1977) Gaddum, J. H., Lembeck, F.: The assay of substances from the adrenal medulla. Br. J. Pharmacol. 4, 401–408 (1949) Greene, E. C.: Anatomy of the rat. New York, London: Hafner Publ. Comp. 1968 Hagmüller, K., Holzer, P.: On the site of action of intravascular GABA on the respiration of the rat. Zool. Jb. Physiol. 82, 505–514 (1978) Hespe, W., Roberts, E., Prins, H.: Autoradiographic investigation of the distribution of (14C) GABA in tissues of normal and aminooxyacetic acid-treated mice. Brain Res. 14, 663–671 (1969) Johnston, G. A. R., Curtis, D. R., Beart P. M., Game, C. J. A., McCulloch, R. M., Twitchin, B.: Cis- and trans-4-aminocrotonic acid as GABA analogues of restricted conformation. J. Neurochem. 24, 157–160 (1975) Kimura, T., Imamura, H., Hashimoto, K.: Facilitatory and inhibitory effects of gamma-aminobutyric acid on ganglionic transmission in the sympathetic cardiac nerves of the dog. J. Pharmacol. Exp. Ther. 202, 397–403 (1977) Krogsgaard-Larsen, P., Johnston, G. A. R., Lodge, D., Curtis, D. R.: A new class of GABA agonist. Nature 268, 53–55 (1977) Kuriyama, K., Sze, P. Y.: Blood-brain barrier to 3H-gammaaminobutyric acid in normal and aminooxyacetic acid-treated animals. Neuropharmacology 10, 103–108 (1971) Levi, G., Amaldi, P., Morisi, G.: Gamma-aminobutyric acid (GABA) uptake by the developing mouse in vivo. Brain Res. 41, 435–451 (1972) Mao, C. C., Costa, E.: Biochemical pharmacology of GABA transmission. In: Psychopharmacology: A generation of progress (M. A. Lipton, A. DiMascio, and K. F. Killam, eds.), pp. 307–318. New York: Raven Press 1978 Musashi, A.: Synthese der Gamma-Aminocrotonsäure und der Gamma-Aminobuttersäure. Hoppe-Seylers Z. Physiol. Chem. 297, 71–73 (1954) Olsen, R. W.: Approaches to study of GABA receptors. In: GABA in nervous system function (E. Roberts, T. N., Chase, and D. B. Tower, eds.), pp. 287–304. New York: Raven Press 1976 Sgaragli, G., Pavan, F.: Effects of amino acid compounds injected into cerebrospinal fluid spaces, on colonic temperature, arterial blood pressure, and behaviour of the rat. Neuropharmacology 11, 45–56 (1972) Stanton, H. C., Woodhouse, F. H.: The effect of gamma-amino-n-butyric acid and some related compounds on the cardiovascular system of anaesthetised dogs. J. Pharmacol. Exp. Ther. 128, 233–242 (1960) Takahashi, H., Tiba, M., Iino, M., Takayasu, T.: The effect of gamma-aminobutyric acid on blood pressure. Jap. J. Physiol. 5, 334–341 (1955) Zukin, S. R., Young, A. B., Snyder, S. H.: Gamma-aminobutyric acid binding to receptor sites in the rat brain central nervous system. Proc. Natl. Acad. Sci. U.S.A. 71, 4802–4807 (1974)