Transglutaminase 2 limits the extravasation and the resultant myocardial fibrosis associated with factor XIII-A deficiency

Atherosclerosis - Tập 294 - Trang 1-9 - 2020
Kathryn J. Griffin1, Laura M. Newell2, Kingsley R. Simpson1, Cora M.L. Beckers1, Mark J. Drinkhill1, Kristina F. Standeven1, Lih T. Cheah1, Siiri E. Iismaa3, Peter J. Grant1, Christopher L. Jackson2, Richard J. Pease1
1Discovery and Translational Science Division, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, LS2 9JT, UK
2Bristol Heart Institute, University of Bristol, Bristol BS2 8HW, UK
3Victor Chang Cardiac Research Institute, Darlinghurst, NSW 2010, Australia

Tài liệu tham khảo

Iismaa, 2009, Transglutaminases and disease: lessons from genetically engineered mouse models and inherited disorders, Physiol. Rev., 89, 991, 10.1152/physrev.00044.2008 Tatsukawa, 2016, Transglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell growth and death, Cell Death Dis., 7, e2244, 10.1038/cddis.2016.150 Brown, 2013, Transglutaminase 2 and NF-kappaB: an odd couple that shapes breast cancer phenotype, Breast Canc. Res. Treat., 137, 329, 10.1007/s10549-012-2351-7 Wang, 2012, TG2, a novel extracellular protein with multiple functions, Amino Acids, 42, 939, 10.1007/s00726-011-1008-x Jin, 2011, Activation of extracellular transglutaminase 2 by thioredoxin, J. Biol. Chem., 286, 37866, 10.1074/jbc.M111.287490 Akimov, 2000, Tissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin, J. Cell Biol., 148, 825, 10.1083/jcb.148.4.825 Cardoso, 2015, Transglutaminase 2 interactions with extracellular matrix proteins as probed with celiac disease autoantibodies, FEBS J., 282, 2063, 10.1111/febs.13276 Nanda, 2001, Targeted inactivation of Gh/tissue transglutaminase II, J. Biol. Chem., 276, 20673, 10.1074/jbc.M010846200 Mearns, 2002, Impaired wound healing and altered fibroblast cytoskeletal dynamics in Gh knockout mice, Minerva Biotecnol., 14, 218 Bakker, 2006, Flow-dependent remodeling of small arteries in mice deficient for tissue-type transglutaminase: possible compensation by macrophage-derived factor XIII 1, Circ. Res., 99, 86, 10.1161/01.RES.0000229657.83816.a7 Bains, 2013, Transglutaminse 2 and EGGL, the protein cross-link formed by transglutaminse 2, as therapeutic targets for disabilities of old age, Rejuvenation Res., 16, 495, 10.1089/rej.2013.1452 Williams, 2010, Effect of transglutaminase 2 (TG2) deficiency on atherosclerotic plaque stability in the apolipoprotein E deficient mouse, Atherosclerosis, 210, 94, 10.1016/j.atherosclerosis.2009.11.014 Van Herck, 2009, Transglutaminase 2 deficiency decreases plaque fibrosis and increases plaque inflammation in apolipoprotein-E-deficient mice, J. Vasc. Res., 47, 231, 10.1159/000255966 Adany, 2003, Factor XIII subunit A as an intracellular transglutaminase, Cell. Mol. Life Sci., 60, 1049, 10.1007/s00018-003-2178-9 Beckers, 2017, Cre/lox studies identify resident macrophages as the major source of circulating coagulation factor XIII-A, Arterioscler. Thromb. Vasc. Biol., 37, 1494, 10.1161/ATVBAHA.117.309271 Muszbek, 2011, Factor XIII: a coagulation factor with multiple plasmatic and cellular functions, Physiol. Rev., 91, 931, 10.1152/physrev.00016.2010 Souri, 2008, Male-specific cardiac pathologies in mice lacking either the A or B subunit of factor XIII, Thromb. Haemost., 99, 401, 10.1160/TH07-10-0599 Koseki-Kuno, 2003, Factor XIII A subunit-deficient mice developed severe uterine bleeding events and subsequent spontaneous miscarriages, Blood, 102, 4410, 10.1182/blood-2003-05-1467 Pawlinski, 2002, Tissue factor deficiency causes cardiac fibrosis and left ventricular dysfunction, Proc. Natl. Acad. Sci. U. S. A, 99, 15333, 10.1073/pnas.242501899 Pawlinski, 2007, Role of cardiac myocyte tissue factor in heart hemostasis, J. Thromb. Haemost., 5, 1693, 10.1111/j.1538-7836.2007.02649.x Noll, 1999, Effect of factor XIII on endothelial barrier function, J. Exp. Med., 189, 1373, 10.1084/jem.189.9.1373 Talman, 2016, Cardiac fibrosis in myocardial infarction-from repair and remodeling to regeneration, Cell Tissue Res., 365, 563, 10.1007/s00441-016-2431-9 Ganame, 2009, Impact of myocardial haemorrhage on left ventricular function and remodelling in patients with reperfused acute myocardial infarction, Eur. Heart J., 30, 1440, 10.1093/eurheartj/ehp093 Gao, 2017, Microvascular leakage in acute myocardial infarction: characterization by histology, biochemistry, and magnetic resonance imaging, Am. J. Physiol. Heart Circ. Physiol., 312, H1068, 10.1152/ajpheart.00073.2017 Szondy, 2017, Transglutaminase 2 in human diseases, Biomedicine, 7, 15, 10.1051/bmdcn/2017070315 Wang, 2018, Cardiac fibrosis can be attenuated by blocking the activity of transglutaminase 2 using a selective small-molecule inhibitor, Cell Death Dis., 9, 613, 10.1038/s41419-018-0573-2 Al Jallad, 2006, Transglutaminase activity regulates osteoblast differentiation and matrix mineralization in MC3T3-E1 osteoblast cultures, Matrix Biol., 25, 135, 10.1016/j.matbio.2005.11.001 Mousa, 2017, Transglutaminases factor XIII-A and TG2 regulate resorption, adipogenesis and plasma fibronectin homeostasis in bone and bone marrow, Cell Death Differ., 24, 844, 10.1038/cdd.2017.21 Lauer, 2002, Targeted inactivation of the mouse locus encoding coagulation factor XIII-A: hemostatic abnormalities in mutant mice and characterization of the coagulation deficit, Thromb. Haemost., 88, 967, 10.1055/s-0037-1613342 Cordell, 2015, Normal bone deposition occurs in mice deficient in factor XIII-A and transglutaminase 2, Matrix Biol., 43, 85, 10.1016/j.matbio.2015.02.001 Iismaa, 2013, Glucose homeostasis in mice is transglutaminase 2 independent, PLoS One, 8, 10.1371/journal.pone.0063346 Livak, 2001, Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method, Methods, 25, 402, 10.1006/meth.2001.1262 Bond, 2011, The fat-fed apolipoprotein E knockout mouse brachiocephalic artery in the study of atherosclerotic plaque rupture, J. Biomed. Biotechnol., 2011, 379069, 10.1155/2011/379069 Boisvert, 2006, Leukocyte transglutaminase 2 expression limits atherosclerotic lesion size, Arterioscler. Thromb. Vasc. Biol., 26, 563, 10.1161/01.ATV.0000203503.82693.c1 Wolfer, 2002, Knockout mice: simple solutions to the problems of genetic background and flanking genes, Trends Neurosci., 25, 336, 10.1016/S0166-2236(02)02192-6 Doetschman, 2009, Influence of genetic background on genetically engineered mouse phenotypes, Methods Mol. Biol., 530, 423, 10.1007/978-1-59745-471-1_23 Hafezi-Moghadam, 2007, ApoE deficiency leads to a progressive age-dependent blood-brain barrier leakage, Am. J. Physiol. Cell Physiol., 292, C1256, 10.1152/ajpcell.00563.2005 Krasemann, 2017, The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases, Immunity, 47, 566, 10.1016/j.immuni.2017.08.008 Levy, 2015, Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration, EMBO Mol. Med., 7, 211, 10.15252/emmm.201404524 Huang, 2010, Do changes in transglutaminase activity alter latent transforming growth factor beta activation in experimental diabetic nephropathy?, Nephrol. Dial. Transplant., 25, 3897, 10.1093/ndt/gfq291 Fisher, 2009, Modulation of tissue transglutaminase in tubular epithelial cells alters extracellular matrix levels: a potential mechanism of tissue scarring, Matrix Biol., 28, 20, 10.1016/j.matbio.2008.10.003 Bernassola, 2002, Role of transglutaminase 2 in glucose tolerance: knockout mice studies and a putative mutation in a MODY patient, FASEB J., 16, 1371, 10.1096/fj.01-0689com Sarvary, 2004, Possible role of factor XIII subunit A in Fcgamma and complement receptor-mediated phagocytosis, Cell. Immunol., 228, 81, 10.1016/j.cellimm.2004.04.007 Matlung, 2009, Calcification locates to transglutaminases in advanced human atherosclerotic lesions, Am. J. Pathol., 175, 1374, 10.2353/ajpath.2009.090012 Haroon, 2001, Localization of tissue transglutaminase in human carotid and coronary artery atherosclerosis: implications for plaque stability and progression, Lab. Investig., 81, 83, 10.1038/labinvest.3780214 Hansson, 2015, Inflammation and plaque vulnerability, J. Intern. Med., 278, 483, 10.1111/joim.12406 Orban, 2004, Crosslinking of collagen gels by transglutaminase, J. Biomed. Mater. Res. A, 68, 756, 10.1002/jbm.a.20110 Ma, 2018, Cardiac fibrosis: new insights into the pathogenesis, Int. J. Biol. Sci., 14, 1645, 10.7150/ijbs.28103 Carcao, 2018, Recombinant FXIII (rFXIII-A2) prophylaxis prevents bleeding and allows for surgery in patients with congenital FXIII A-subunit deficiency, Thromb. Haemost., 118, 451, 10.1055/s-0038-1624581 Heidt, 2014, Differential contribution of monocytes to heart macrophages in steady-state and after myocardial infarction, Circ. Res., 115, 284, 10.1161/CIRCRESAHA.115.303567 Small, 1999, Cardiac specific overexpression of transglutaminase II (G(h)) results in a unique hypertrophy phenotype independent of phospholipase C activation, J. Biol. Chem., 274, 21291, 10.1074/jbc.274.30.21291