Transcriptomic changes in autophagy-related genes are inversely correlated with inflammation and are associated with multiple sclerosis lesion pathology
Tài liệu tham khảo
Albert, 2017, Synaptic pathology in the cerebellar dentate nucleus in chronic multiple sclerosis, Brain Pathol., 27, 737, 10.1111/bpa.12450
Beek, 2018, Genetic aberrations in macroautophagy genes leading to diseases, Biochim. Biophys. Acta Mol. Cell Res., 1865, 803, 10.1016/j.bbamcr.2018.03.002
Bhattacharya, 2014, Deficiency of autophagy in dendritic cells protects against experimental autoimmune encephalomyelitis, J. Biol. Chem., 289, 26525, 10.1074/jbc.M114.575860
Bjornevik, 2022, Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis, Science (New York, N.Y.), 301, 296, 10.1126/science.abj8222
Bordi, 2021, A gene toolbox for monitoring autophagy transcription, Cell Death Dis., 12, 1, 10.1038/s41419-021-04121-9
Borjini, 2016, Cytokine and chemokine alterations in tissue, CSF, and plasma in early presymptomatic phase of experimental allergic encephalomyelitis (EAE), in a rat model of multiple sclerosis, J. Neuroinflammation, 13, 1, 10.1186/s12974-016-0757-6
Boyao, 2019, Dynamic expression of autophagy-related factors in autoimmune encephalomyelitis and exploration of curcumin therapy, J. Neuroimmunol., 337
Brady, 2018, Emerging roles for TFEB in the immune response and inflammation, Autophagy, 14, 181, 10.1080/15548627.2017.1313943
Chen, 2012, MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB, Autophagy, 8
Levine, 2013, Mechanisms of disease: autophagy in human health and disease, N. Engl. J. Med., 368, 651, 10.1056/NEJMra1205406
Chowdhury, 2015, Ribosomal protein S6 phosphorylation is controlled by TOR and modulated by PKA in Candida Albicans, Mol. Microbiol., 98, 384, 10.1111/mmi.13130
Constantinescu, 2011, Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS), Br. J. Pharmacol., 164, 1079, 10.1111/j.1476-5381.2011.01302.x
Deretic, 2021, Autophagy in inflammation, infection, and immunometabolism, Immunity, 54, 437, 10.1016/j.immuni.2021.01.018
Deretic, 2013, Autophagy in infection, inflammation and immunity, Nat. Rev. Immunol., 13, 722, 10.1038/nri3532
Dobson, 2019, Multiple sclerosis – a review, Eur. J. Neurol., 26, 27, 10.1111/ene.13819
Dyment, 2006, Multiple sclerosis in stepsiblings: recurrence risk and ascertainment, J. Neurol. Neurosurg. Psychiatr., 77, 258, 10.1136/jnnp.2005.063008
Feng, 2017, Defective autophagy is associated with neuronal injury in a mouse model of multiple sclerosis, Bosn. J. Basic Med. Sci., 17, 95
He, 2009, Regulation mechanisms and signaling pathways of autophagy, Annu. Rev. Genet., 43, 67, 10.1146/annurev-genet-102808-114910
Hofstetter, 2002, Pertussis toxin modulates the immune response to neuroantigens injected in incomplete Freund's adjuvant: induction of Th1 cells and experimental autoimmune encephalomyelitis in the presence of high frequencies of Th2 cells, J. Immunol., 169, 117, 10.4049/jimmunol.169.1.117
Klionsky, 2021, Guidelines for the use and interpretation of assays for monitoring autophagy (4th Edition)1, Autophagy, 17, 1, 10.1080/15548627.2020.1797280
Kuhlmann, 2017, An updated histological classification system for multiple sclerosis lesions, Acta Neuropathol., 133, 13, 10.1007/s00401-016-1653-y
Lahiri, 2019, Watch what you (Self-) eat: autophagic mechanisms that modulate metabolism, Cell Metabol., 29, 803, 10.1016/j.cmet.2019.03.003
Levine, 2019, Biological functions of autophagy genes: a disease perspective, Cell, 176, 11, 10.1016/j.cell.2018.09.048
Levine, 2011, Autophagy in immunity and inflammation, Nature, 469, 323, 10.1038/nature09782
Li, 2006, Autophagy is induced in CD4 + T cells and important for the growth factor-withdrawal cell death, J. Immunol., 177, 5163, 10.4049/jimmunol.177.8.5163
Liu, 2016, P62 links the autophagy pathway and the ubiqutin-proteasome system upon ubiquitinated protein degradation, Cell. Mol. Biol. Lett., 21, 1, 10.1186/s11658-016-0031-z
Livak, 2001, Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method, Methods, 25, 402, 10.1006/meth.2001.1262
Martina, 2014, The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris, Sci. Signal., 7, 1, 10.1126/scisignal.2004754
Miedema, 2020, High-resolution transcriptomic and proteomic profiling of heterogeneity of brain-derived microglia in multiple sclerosis, Front. Mol. Neurosci., 13
Miller, 2007, Primary-progressive multiple sclerosis, Lancet Neurol., 6, 903, 10.1016/S1474-4422(07)70243-0
Misrielal, 2020, Autophagy in multiple sclerosis: two sides of the same coin, Front. Cell. Neurosci., 14
Mizushima, 2010, Methods in mammalian autophagy research, Cell, 140, 313, 10.1016/j.cell.2010.01.028
Moulis, 2017, Methods for measuring autophagy in mice, Cells, 6, 1, 10.3390/cells6020014
Nakatogawa, 2020, Mechanisms governing autophagosome biogenesis, Nat. Rev. Mol. Cell Biol., 21, 439, 10.1038/s41580-020-0241-0
Nirk, 2020, Hydroxychloroquine in rheumatic autoimmune disorders and beyond, EMBO Mol. Med., 12, 1, 10.15252/emmm.202012476
Patergnani, 2021, Antipsychotic drugs counteract autophagy and mitophagy in multiple sclerosis, Proc. Natl. Acad. Sci. U.S.A., 118, 1, 10.1073/pnas.2020078118
Pyka-Fościak, 2020, Changes in spinal cord stiffness in the course of experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis, Arch. Biochem. Biophys., 680, 10.1016/j.abb.2019.108221
Sawcer, 2011, Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis, Nature, 476, 214, 10.1038/nature10251
Schneider, 2012, NIH image to ImageJ: 25 Years of image analysis, Nat. Methods, 9, 671, 10.1038/nmeth.2089
Vainchtein, 2014, In acute experimental autoimmune encephalomyelitis, infiltrating macrophages are immune activated, whereas microglia remain immune suppressed, Glia, 62, 1724, 10.1002/glia.22711
Valk, 2000, Staging of multiple sclerosis (MS) lesions: pathology of the time frame of MS, Neuropathol. Appl. Neurobiol., 26, 2, 10.1046/j.1365-2990.2000.00217.x
Yin, 2018, The therapeutic and pathogenic role of autophagy in autoimmune diseases, Front. Immunol., 9, 1512, 10.3389/fimmu.2018.01512
Zachari, 2017, The mammalian ULK1 complex and autophagy initiation, Essays Biochem., 61, 585, 10.1042/EBC20170021