Transcriptomic analysis reveals the promotion of lymph node metastasis by Helicobacter pylori infection via upregulating chemokine (C-X-C motif) receptor 2 expression in gastric carcinoma

Genes and Diseases - Tập 10 - Trang 2614-2621 - 2023
Lang Zha1, Xiong Guo1, Xiaolong Liang1, Yuedong Chen2, Deyong Gan2, Wenwen Li3, Ziwei Wang1, Hongyu Zhang1
1Department of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China
2Department of Gastrointestinal Surgery, The Tongliang Hospital of the First Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China
3Department of Pathology, Faculty of Basic Medicine, Chongqing Medical University, Chongqing, 400016, China

Tài liệu tham khảo

Sung, 2021, Global cancer statistics 2020:GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA A Cancer J Clin, 71, 209, 10.3322/caac.21660 Ford, 2020, Helicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis, Gut, 69, 2113, 10.1136/gutjnl-2020-320839 Imazeki, 1992, p53 gene mutations in gastric and esophageal cancers, Gastroenterology, 103, 892, 10.1016/0016-5085(92)90022-Q Tanner, 2005, Amplification of HER-2 in gastric carcinoma: association with Topoisomerase IIα gene amplification, intestinal type, poor prognosis and sensitivity to trastuzumab, Ann Oncol, 16, 273, 10.1093/annonc/mdi064 Graziano, 2003, The role of the E-cadherin gene (CDH1) in diffuse gastric cancer susceptibility: from the laboratory to clinical practice, Ann Oncol, 14, 1705, 10.1093/annonc/mdg486 Allgayer, 2000, C-erbB-2 is of independent prognostic relevance in gastric cancer and is associated with the expression of tumor-associated protease systems, J Clin Oncol, 18, 2201, 10.1200/JCO.2000.18.11.2201 Canale, 2020, Epigenetic mechanisms in gastric cancer: potential new therapeutic opportunities, Int J Mol Sci, 21, 5500, 10.3390/ijms21155500 Hanahan, 2000, The hallmarks of cancer, Cell, 100, 57, 10.1016/S0092-8674(00)81683-9 Hanahan, 2011, Hallmarks of cancer: the next generation, Cell, 144, 646, 10.1016/j.cell.2011.02.013 Busuttil, 2021, SFRP4 drives invasion in gastric cancer and is an early predictor of recurrence, Gastric Cancer, 24, 589, 10.1007/s10120-020-01143-8 Yang, 2021, A comprehensive update on early gastric cancer: defining terms, etiology, and alarming risk factors, Expet Rev Gastroenterol Hepatol, 15, 255, 10.1080/17474124.2021.1845140 Subramanian, 2005, Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles, Proc Natl Acad Sci U S A, 102, 15545, 10.1073/pnas.0506580102 Mootha, 2003, PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes, Nat Genet, 34, 267, 10.1038/ng1180 Liberzon, 2015, The Molecular Signatures Database (MSigDB) hallmark gene set collection, Cell Syst, 1, 417, 10.1016/j.cels.2015.12.004 Chu, 2022, Comparative study of modified silver nitrate staining for the detection of Helicobacter pylori, Appl Immunohistochem Mol Morphol, 30, 340, 10.1097/PAI.0000000000001010 Xiang, 2017, A positive crosstalk between CXCR4 and CXCR2 promotes gastric cancer metastasis, Oncogene, 36, 5122, 10.1038/onc.2017.108 Wang, 2015, The prognostic value of CXC-chemokine receptor 2 (CXCR2) in gastric cancer patients, BMC Cancer, 15, 766, 10.1186/s12885-015-1793-9 Li, 2014, Association of CXCR1 and 2 expressions with gastric cancer metastasis in ex vivo and tumor cell invasion, in vitro. Cytokine, 69, 6, 10.1016/j.cyto.2014.05.004 Kasashima, 2017, Clinicopathologic significance of the CXCL1-CXCR2 axis in the tumor microenvironment of gastric carcinoma, PLoS One, 12, 10.1371/journal.pone.0178635 Yang, 2016, Association between CXCR2 and IL-22BP expression indicate a poor outcome for gastric adenocarcinoma progression, Oncol Lett, 12, 1477, 10.3892/ol.2016.4790 Xu, 2012, Lymphatic endothelial cell-secreted CXCL1 stimulates lymphangiogenesis and metastasis of gastric cancer, Int J Cancer, 130, 787, 10.1002/ijc.26035 Pastushenko, 2019, EMT transition states during tumor progression and metastasis, Trends Cell Biol, 29, 212, 10.1016/j.tcb.2018.12.001 Brabletz, 2018, EMT in cancer, Nat Rev Cancer, 18, 128, 10.1038/nrc.2017.118 Wang, 2018, ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway, Biomed Pharmacother, 97, 1066, 10.1016/j.biopha.2017.11.034 Zha, 2013, HMGA2 elicits EMT by activating the Wnt/β-catenin pathway in gastric cancer, Dig Dis Sci, 58, 724, 10.1007/s10620-012-2399-6 Feng, 2020, Correlations of recurrence of gastric cancer in patients after radical surgery with serum gastrointestinal hormones, vascular endothelial growth factors and serum anti-Helicobacter pylori IgG antibody, J BUON, 25, 1476 Bäckhed, 2003, Helicobacter pylori infection induces interleukin-8 receptor expression in the human gastric epithelium, Infect Immun, 71, 3357, 10.1128/IAI.71.6.3357-3360.2003 Ahuja, 1992, Molecular evolution of the human interleukin-8 receptor gene cluster, Nat Genet, 2, 31, 10.1038/ng0992-31 Xu, 2018, CXCR2 promotes breast cancer metastasis and chemoresistance via suppression of AKT1 and activation of COX2, Cancer Lett, 412, 69, 10.1016/j.canlet.2017.09.030 Han, 2012, High expression of CXCR2 is associated with tumorigenesis, progression, and prognosis of laryngeal squamous cell carcinoma, Med Oncol, 29, 2466, 10.1007/s12032-011-0152-1 Sui, 2014, High expression of CXCR-2 correlates with lymph node metastasis and predicts unfavorable prognosis in resected esophageal carcinoma, Med Oncol, 31, 809, 10.1007/s12032-013-0809-z Zhao, 2017, Overexpression of CXCR2 predicts poor prognosis in patients with colorectal cancer, Oncotarget, 8, 28442, 10.18632/oncotarget.16086 Yang, 2010, CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis, Clin Cancer Res, 16, 3875, 10.1158/1078-0432.CCR-10-0483 Wu, 2022, Feiyanning downregulating CXCLs/CXCR2 axis to suppress TANs infiltration in the prevention of lung cancer metastasis, J Ethnopharmacol, 295, 10.1016/j.jep.2022.115277 Sueoka, 2014, Blockage of CXCR2 suppresses tumor growth of intrahepatic cholangiocellular carcinoma, Surgery, 155, 640, 10.1016/j.surg.2013.12.037 Steele, 2016, CXCR2 inhibition profoundly suppresses metastases and augments immunotherapy in pancreatic ductal adenocarcinoma, Cancer Cell, 29, 832, 10.1016/j.ccell.2016.04.014 Sano, 2019, Blocking CXCLs-CXCR2 axis in tumor-stromal interactions contributes to survival in a mouse model of pancreatic ductal adenocarcinoma through reduced cell invasion/migration and a shift of immune-inflammatory microenvironment, Oncogenesis, 8, 8, 10.1038/s41389-018-0117-8 Munari, 2011, Tumor-associated macrophages as major source of APRIL in gastric MALT lymphoma, Blood, 117, 6612, 10.1182/blood-2010-06-293266 Sugizaki, 2018, Anti-Helicobacter pylori therapy in localized gastric mucosa-associated lymphoid tissue lymphoma: a prospective, nationwide, multicenter study in Japan, Helicobacter, 23, 10.1111/hel.12474 Devi, 2014, Helicobacter pylori antigen HP0986 (TieA) interacts with cultured gastric epithelial cells and induces IL8 secretion via NF-κB mediated pathway, Helicobacter, 19, 26, 10.1111/hel.12100