Transcriptional Landscape of a blaKPC-2 Plasmid and Response to Imipenem Exposure in Escherichia coli TOP10

Agnès B. Jousset1,2,3,4, Isabelle Rosinski‐Chupin5,4, Julie Takissian3,4, Philippe Glaser5,4, Rémy A. Bonnin1,3,4, Thierry Naas1,2,3,4
1Associated French National Reference Center for Antibiotic Resistance, Le Kremlin-Bicêtre, France
2Department of Bacteriology-Parasitology-Hygiene, Bicêtre Hospital, Assistance Publique-Hôpitaux de Paris, Le Kremlin-Bicêtre, France
3EA7361 "Structure, dynamic, function and expression of broad spectrum β-lactamases", Faculty of Medicine, Paris-Sud University, Le Kremlin-Bicêtre, France
4Joint Research Unit Evolution and Ecology of Resistance to Antibiotics, Institut Pasteur-APHP-University Paris Sud, Paris, France
5CNRS, UMRS 3525, Paris, France

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