Transcatheter aortic valve replacement in patients with severe aortic stenosis and heart failure

Heart Failure Reviews - Tập 23 - Trang 821-829 - 2018
Chirag Bavishi1, Dhaval Kolte1, Paul C. Gordon1, J. Dawn Abbott1
1Department of Medicine, Division of Cardiology Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, USA

Tóm tắt

Severe aortic stenosis (AS) and heart failure (HF) represent an important and high-risk group of patients who are often referred for transcatheter aortic valve replacement (TAVR) due to high risk for surgical intervention. Thus far, randomized controlled trials have shown comparable outcomes between TAVR and surgical aortic valve replacement in patients with severe AS and heart failure with reduced ejection fraction. In the current review, we will discuss (1) the pathophysiology of HF in patients with severe AS, (2) role of imaging modalities in management, (3) role of biomarkers of HF on prognosis, (4) impact of other valvular heart diseases, (5) evidence from the contemporary trials on the role of TAVR in patients with severe AS and HF, and (6) future directions and research.

Tài liệu tham khảo

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