Training Needs of Clinical and Research Professionals to Optimize Minority Recruitment and Retention in Cancer Clinical Trials
Tóm tắt
The study of disparities in minority recruitment to cancer clinical trials has focused primarily on inquiries among minority patient populations. However, clinical trial recruitment is complex and requires a broader appreciation of the multiple factors that influence minority participation. One area that has received little attention is minority recruitment training for professionals who assume various roles in the clinical trial recruitment process. Therefore, we assessed the perspectives of cancer center clinical and research personnel on their training and education needs toward minority recruitment for cancer clinical trials. Ninety-one qualitative interviews were conducted at five U.S. cancer centers among four stakeholder groups: cancer center leaders, principal investigators, referring clinicians, and research staff. Interviews were recorded and transcribed. Qualitative analyses focused on response data related to training for minority recruitment for cancer clinical trials. Four prominent themes were identified: (1) Research personnel are not currently being trained to focus on recruitment and retention of minority populations; (2) Training for minority recruitment and retention provides for a specific focus on factors influencing minority research participation; (3) Training on cultural awareness may help to bridge cultural gaps between potential minority participants and research professionals; (4) Views differ regarding the importance of research personnel training designed to focus on recruitment of minority populations. There is a lack of systematic training for minority recruitment. Many stakeholders acknowledged the benefits of minority recruitment training and welcomed training that focuses on increasing cultural awareness to increase the participation of minorities in cancer clinical trials.
Tài liệu tham khảo
Health, U.D.o. and H. Services (1994) NIH guidelines on the inclusion of women and minorities as subjects in clinical research. Fed Regist 59(59):14508–14513
Giuliano AR et al (2000) Participation of minorities in cancer research: the influence of structural, cultural, and linguistic factors. Ann Epidemiol 10(8):S22–S34
Scalici J et al (2015) Minority participation in gynecologic oncology group (GOG) studies. Gynecol Oncol 138(2):441–444
Siegel RL, Miller KD, Jemal A (2016) Cancer statistics, 2016. CA Cancer J Clin 66(1):7–30
DeSantis CE et al (2016) Breast cancer statistics, 2015: convergence of incidence rates between black and white women. CA Cancer J Clin 66(1):31–42
Ford JG et al (2008) Barriers to recruiting underrepresented populations to cancer clinical trials: a systematic review. Cancer 112(2):228–242
Howerton MW et al (2007) Provider roles in the recruitment of underrepresented populations to cancer clinical trials. Cancer 109(3):465–476
Durant RW et al (2014) Perspectives on barriers and facilitators to minority recruitment for clinical trials among cancer center leaders, investigators, research staff, and referring clinicians: enhancing minority participation in clinical trials (EMPaCT). Cancer 120(S7):1097–1105
Rivers D et al (2013) A systematic review of the factors influencing African Americans' participation in cancer clinical trials. Contemp Clin Trials 35(2):13–32
Germino BB et al (2011) Engaging African American breast cancer survivors in an intervention trial: culture, responsiveness and community. J Cancer Surviv 5(1):82–91
Robins Sadler G et al (2006) Health parties for African American study recruitment. J Cancer Educ 21(2):71–76
Jones RA, Steeves R, Williams I (2009) Strategies for recruiting African American men into prostate cancer screening studies. Nurs Res 58(6):452
Ford ME, Siminoff LA, Pickelsimer E, Mainous AG, Smith DW, Diaz VA, Soderstrom LH, Jefferson MS, Tilley BC (2013) Unequal burden of disease, unequal participation in clinical trials: solutions from African American and Latino community members. Health Soc Work 38(1):29–38
Ma GX, Tan Y, Blakeney NC, Seals BF, Ma XS, Zhai S, Liu A, Tai Y, Michaels M (2013) The impact of a community-based clinical trial educational intervention among underrepresented Chinese Americans. Cancer Epidemiol Biomark Prev 23(3):424–32
Anwuri VV et al (2013) An institutional strategy to increase minority recruitment to therapeutic trials. Cancer Causes Control 24(10):1797–1809
Quinn GP et al (2011) Enhancing oncology health care provider's sensitivity to cultural communication to reduce cancer disparities: a pilot study. J Cancer Educ 26(2):322
Wallington SF et al (2016) Enrolling minority and underserved populations in cancer clinical research. Am J Prev Med 50(1):111–117
Betancourt JR et al (2003) Defining cultural competence: a practical framework for addressing racial/ethnic disparities in health and health care. Public Health Rep 118(4):293–302
Smith WR et al (2007) Recommendations for teaching about racial and ethnic disparities in health and health care. Ann Intern Med 147(9):654–664
Association, W.M (2015) WMA declaration of Geneva. Int J Person Cent Med 4(3):157
Nelson AR, AY Stith, and BD Smedley (2003) Unequal treatment: confronting racial and ethnic disparities in health care (full printed version). National Academies Press, Washington
Abernethy A et al (2014) Turning the tide against cancer through sustained medical innovation: the pathway to progress. Clin Cancer Res 20(5):1081–1086
Bergenmar M, Johansson H, Wilking N (2011) Levels of knowledge and perceived understanding among participants in cancer clinical trials–factors related to the informed consent procedure. Clin Trials 8(1):77–84
Albrecht TL et al (2008) Influence of clinical communication on patients' decision making on participation in clinical trials. J Clin Oncol 26(16):2666–2673
Durant RW et al (2011) Different types of distrust in clinical research among whites and African Americans. J Natl Med Assoc 103(2):123–130