Toxicological profile and acetylcholinesterase inhibitory potential of Palicourea deflexa, a source of β-carboline alkaloids

Pablo Ricardo Bertelli1, Renata Biegelmeyer1, Eduardo Pacheco Rico2, Luiz Carlos Klein-Junior1, Natally S.B. Toson1, Luciane Minetto3, Sergio A.L. Bordignon4, André L. Gasper5, Sidnei Moura3, Diogo L. de Oliveira6, Amélia T. Henriques1
1Laboratory of Pharmacognosy, Faculty of Pharmacy, Universidade Federal do Rio Grande do Sul – UFRGS, Porto Alegre, RS, Brazil
2Graduate Program in Health Sciences, Universidade do Extremo Sul Catarinense - UNESC, Criciúma, SC, Brazil
3Laboratory of Synthetic and Natural Products Biotechnology, Institute of Biotechnology, Universidade de Caxias do Sul – UCS, Caxias do Sul, RS, Brazil
4Laboratory of Conservation and Biodiversity Management, Universidade Lasalle – UNILASALLE, Canoas, RS, Brazil
5Herbarium Dr. Roberto Miguel Klein, Department of Natural Sciences, Universidade Regional de Blumenau - FURB, Blumenau, SC, Brazil
6Graduate Program in Biological Sciences: Biochemistry, Department of Biochemistry, Universidade Federal do Rio Grande do Sul – UFRGS, Porto Alegre, RS, Brazil

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