Topoisomerase I inhibitors: selectivity and cellular resistance
Tài liệu tham khảo
Gupta, 1995, Eukaryotic DNA topoisomerases I, Biochim Biophys Acta, 1262, 1, 10.1016/0167-4781(95)00029-G
Wang, 1996, DNA topoisomerases, Annu Rev Biochem, 65, 635, 10.1146/annurev.bi.65.070196.003223
Champoux, 1998, Domains of human topoisomerase I and associated functions, Prog Nucleic Acids Res Mol Biol, 60, 111, 10.1016/S0079-6603(08)60891-0
Redinbo, 1999, Structural insights into the function of type IB topoisomerases, Curr Opin Struct Biol, 9, 29, 10.1016/S0959-440X(99)80005-0
Pommier, 1998, Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme, Biochim Biophys Acta, 1400, 83, 10.1016/S0167-4781(98)00129-8
Chen, 1994, DNA Topoisomerases: essential enzymes and lethal targets, Annu Rev Pharmacol Toxicol, 94, 194
Pommier, 1994, Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors, Cancer Invest, 12, 530, 10.3109/07357909409021413
Pommier, 1996, DNA topoisomerase I inhibitors and multidrug resistance, 119
Larsen, 1998, Cellular resistance to topoisomerase I-targeted druugs: from drug uptake to cell death, Biochim Biophys Acta, 1400, 257, 10.1016/S0167-4781(98)00140-7
Benedetti, 1998, Analysis of camptothecin resistance in yeast: relevance to cancer therapy, Drug Resist Updates, 1, 176, 10.1016/S1368-7646(98)80037-X
Pourquier, 1999, Human DNA topoisomerase I-mediated cleavage and recombination of duck hepatitis B virus DNA in vitro, Nucleic Acids Res, 27, 1919, 10.1093/nar/27.8.1919
Wu, 1997, Processing of topoisomerase I cleavable complexes into DNA damage by transcription, Nucleic Acids Res, 25, 4181, 10.1093/nar/25.21.4181
Pommier, 1999, Topoisomerase inhibitors: Why develop new ones, Opinion in Oncologic, Endocrine & Metabolic Investigational Drugs, 1, 168
Poddevin, 1993, Dual topoisomerase I and II inhibition by intoplicine (RP-60475) a new antitumor agent in early clinical trials, Mol Pharmacol, 44, 767
Bailly, 1997, DNA cleavage by topoisomerase I in the presence of indolocarbazole derivatives of rebeccamycin, Biochemistry, 36, 3917, 10.1021/bi9624898
Strumberg, 1999, Synthesis of cytotoxic indenoisoquinoline topoisomerase I poisons, J Med Chem, 42, 446, 10.1021/jm9803323
Bailly, 1999, Intercalation into DNA is not required for inhibition of topoisomerase I by indolocarbazole antitumor agents, Cancer Res, 59, 2853
Tanizawa, 1994, Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials, J Natl Cancer Inst, 86, 836, 10.1093/jnci/86.11.836
Tanizawa, 1995, Differential stabilization of eukaryotic DNA topoisomerase I cleavable complexes by camptothecin derivatives, Biochemistry, 34, 7200, 10.1021/bi00021a035
Potter, 1998, Cellular localization domains of a rabbit and a human carboxylesterase: influence on irinotecan (CPT-11) metabolism by the rabbit enzyme, Cancer Res, 58, 3627
Morton, 1999, The anticancer prodrug CPT-11 is a potent inhibitor of acetylcholinesterase but is rapidly catalyzed to SN-38 by butyrylcholinesterase, Cancer Res, 59, 1458
Haaz, 1997, The transformation of irinotecan (CPT-11) to its active metabolite SN-38 by human liver microsomes. Differential hydrolysis for the lactone and carboxylate forms, Naunyn Schmiedebergs Arch Pharmacol, 356, 257, 10.1007/PL00005049
Niimi, 1992, Mechanism of cross-resistane to a camptothecin analogue (CPT-11) in a human ovarian cancer cell line selected by cisplatin, Cancer Res, 52, 328
Kanzawa, 1990, Establishement of a camptothecin analogue (CPT-11)-resistant cell line of human non-small cell lung cancer: characterization and mechanism of resistance, Cancer Res, 50, 5919
Nagai, 1995, Establishment and characterization of human gastric and colonic xenograft lines resistant to CPT-11 (a new derivative of camptothecin), J Surg Oncol, 59, 116, 10.1002/jso.2930590209
Saijo, 1994, 7-Ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxy camptothecin: mechanism of resistance and clinical trials, Cancer Chemother Pharmacol, 34 Suppl, S112, 10.1007/BF00684874
Danks, 1998, Overexpression of a rabbit liver carboxylesterase sensitizes human tumor cells to CPT-11, Cancer Res, 58, 20
Rivory, 1996, Identification and properties of a major plasma metabolite of irinotecan (CPT-11) isolated from the plasma of patients, Cancer Res, 56, 3689
Rosing, 1998, O-glucuronidation, a newly identified metabolic pathway for topotecan and N-desmethyltopotecan, Anticancer Drugs, 9, 587, 10.1097/00001813-199808000-00002
Gupta, 1994, Metabolic fate of irinotecan in humans: correlation of glucuronidation with diarrhea, Cancer Res, 54, 3723
Rivory, 1995, Identification and kinetics of a beta-glucuronide metabolite of SN-38 in human plasma after administration of the camptothecin derivative irinotecan, Cancer Chemother Pharmacol, 36, 176, 10.1007/BF00689205
Iyer, 1998, Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes, J Clin Invest, 101, 847, 10.1172/JCI915
Lyer, 1998, Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes, J Clin Invest, 101, 847, 10.1172/JCI915
Wasserman, 1997, Severe CPT-11 toxicity in patients with Gilbert’s syndrome: two case reports, Ann Oncol, 8, 1049, 10.1023/A:1008261821434
Takahashi, 1997, The role of glucuronidation in 7-ethyl-10-hydroxycamptothecin resistance in vitro, Jpn J Cancer Res, 88, 1211, 10.1111/j.1349-7006.1997.tb00351.x
Hendricks, 1992, Effect of P-glycoprotein expression on the accumulation and cytotoxicity of topotecan (SK&F 104864), a new camptothecin analogue, Cancer Res, 52, 2268
Ambudkar, 1992, Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis, Proc Natl Acad Sci USA, 89, 8472, 10.1073/pnas.89.18.8472
Hoki, 1997, Differential cytotoxcity of clinically important camptothecin derivatives in P-glycoprotein-overexpressing cell lines, Cancer Chemother Pharmacol, 40, 433, 10.1007/s002800050682
Mattern, 1993, In vitro and in vivo effects of clinically important camptothecin analogues on multidrug-resistant cells, Oncol Res, 5, 467
Jansen, 1998, CPT-11 sensitivity in relation to the expression of P170-glycoprotein and multidrug resistance-associated protein, Br J Cancer, 77, 359, 10.1038/bjc.1998.58
Chen, 1999, ATP-dependent efflux of CPT-11 and SN-38 by the multidrug resistance protein (MRP) and its inhibition by PAK-104P, Mol Pharmacol, 55, 921
Yang, 1995, Cross-resistance to camptothecin analogues in mitoxantrone-resistant human breast carcinoma cell line is not due to DNA topoisomerase I alterations, Cancer Res, 55, 4004
Ma, 1998, Reduced cellular accumulation of topotecan: a novel mechanism of resistance in a human ovarian cancer cell line, Br J Cancer, 77, 1645, 10.1038/bjc.1998.270
Brangi, 1999, Camptothecin resistance: role of the ABC half-transporter, MXR, and potential for glucuronidation in MXR-expressing cells, Cancer Res
Miyake, 1999, Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology of ABC transport genes, Cancer Res, 59, 8
Maliepaard, 1999, Overexpression of the BCRP/MXR/ABCP gene in a topotecan-selected ovarian tumor cell line [In Process Citation], Cancer Res, 59, 4559
Redinbo, 1998, Crystal structure of human topoisomerase I in covalent and noncovalent complexes with DNA, Science, 279, 1504, 10.1126/science.279.5356.1504
Stewart, 1998, A model for the mechanism of human topoisomerase I, Science, 279, 1534, 10.1126/science.279.5356.1534
Stewart, 1997, Reconstitution of human topoisomerase I by fragment complementation, J Mol Biol, 269, 355, 10.1006/jmbi.1997.1056
Simmons, 1996, Simian virus 40 large T antigen binds to topoisomerase I, Virology, 222, 365, 10.1006/viro.1996.0433
Pommier, 1998, Mammalian DNA topoisomerase I activity and poisoning by camptothecin are inhibited by simian virus 40 large T antigen, Biochemistry, 10.1021/bi972067d
Merino, 1993, DNA topoisomerase I is involved in both repression and activation of transcription, Nature, 365, 227, 10.1038/365227a0
Bharti, 1996, Identification of a nucleophilin binding site in human topoisomerase I, J Biol Chem, 271, 1993, 10.1074/jbc.271.4.1993
Haluska, 1999, Interaction between human topoisomerase I and a novel RING finger/arginine-serine protein, Nucleic Acids Res, 27, 2538, 10.1093/nar/27.12.2538
Kikuchi, 1993, Expression of human type I and II DNA topoisomerases and their derivatives in Escherichia coli, 121
Pommier, 1995, Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites, Proc Natl Acad Sci USA, 92, 8861, 10.1073/pnas.92.19.8861
Jaxel, 1991, Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin, J Biol Chem, 266, 20418, 10.1016/S0021-9258(18)54939-5
Fan, 1998, Molecular modeling studies of the DNA topoisomerase I ternary complex with camptothecin, J Med Chem, 41, 2216, 10.1021/jm9605445
Komatani, 1999, A new mechanism of acquisition of drug resistance by partial duplication of topoisomerase I, Cancer Res, 59, 2701
Andoh, 1987, Characterization of a mammalian mutant with a camptothecin resistant DNA topoisomerase I, Proc Natl Acad Sci USA, 84, 5565, 10.1073/pnas.84.16.5565
Tan, 1989, Nonproductive rearrangement of DNA topoisomerase I and II genes: correlation with resistance to topoisomerase inhibitors, J Natl Cancer Inst, 81, 1732, 10.1093/jnci/81.22.1732
Sugimoto, 1990, Decreased expression of DNA topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody, Cancer Res, 50, 6925
Woessner, 1993, Camptothecin hyper-resistant P388 cells: drug-dependent reduction in topoisomerase I content, Oncol Res, 4, 481
Chang, 1992, Characterization of camptothecin-resistant chinese hamster lung cells, Biochem Pharmacol, 43, 2443, 10.1016/0006-2952(92)90325-D
Fujimori, 1995, Mutation at the catalytic site of topoisomerase I in CEM/C2, a human leukemia cell resistant to camptothecin, Cancer Res, 55, 1339
Eng, 1990, Development of a stable camptothecin-resistant subline of P388 leukemia with reduced topoisomerase I content, Mol Pharmacol, 38, 471
Fujimori, 1996, Silencing and selective methylation of the normal topoisomerase I gene in camptothecin-resistant CEM/C2 human leukemia cells, Oncol Res, 295
Madelaine, 1993, Sequential modifications of topoisomerase I activity in a camptothecin-resistant cell line established by progressive adaptation, Biochem Pharmacol, 45, 339, 10.1016/0006-2952(93)90069-9
Gupta, 1988, Camptothecin-resistant mutants of Chinese hamster ovary cells containing a resistant form of topoisomerase I, Cancer Res, 48, 6404
Oguro, 1990, Collateral drug sensitivity induced in CPT-11 (a novel derivative of camptothecin)-resistant cell lines, Biomed Pharmacother, 209, 10.1016/0753-3322(90)90026-6
Tan, 1992, Topoisomerase II-alpha and topoisomerase II-beta genes: characterization and mapping to human chromosomes 17 and 3, respectively, Cancer Res, 52, 231
Sorensen, 1995, Characterisation of a human small-cell lung cancer cell line resistant to the DNA topoisomerase I-directed drug topotecan, Br J Cancer, 72, 399, 10.1038/bjc.1995.345
Goldwasser, 1996, Correlations between S- and G2-phase arrest and cytotoxicity of camptothecin in human colon carcinoma cells, Cancer Res, 56, 4430
Nitiss, 1996, Mechanisms of cell killing by drugs that trap covalent complexes between DNA topoisomerases and DNA, Mol Pharmacol, 50, 1095
Morris, 1996, Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity, J Cell Biol, 134, 757, 10.1083/jcb.134.3.757
Borovitskaya, 1998, Replication-dependent and -independent camptothecin cytotoxicity of seven human colon tumor cell lines, Oncol Res, 10, 271
Pourquier, 1997, Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I, J Biol Chem, 272, 7792, 10.1074/jbc.272.12.7792
Pourquier, 1997, Trapping of mammalian topoisomerase I and recombinations induced by damaged DNA containing nicks or gaps: importance of DNA end phosphorylation and camptothecin effects, J Biol Chem, 272, 26441, 10.1074/jbc.272.42.26441
Pourquier, 1998, Induction of topoisomerase I cleavage complexes by the vinyl chloride adduct, 1, N6-ethenoadenine, J Biol Chem, 273, 27245, 10.1074/jbc.273.42.27245
Pommier, 1999, Induction of topoisomerase I-mediated DNA cleavage and recombinations by benzo[a]pyrene diol epoxide-DNA adducts, Proc Natl Acad Sci USA, in press
Desai, 1997, Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin, J Biol Chem, 272, 24159, 10.1074/jbc.272.39.24159
Beidler, 1995, Camptothecin induction of a time- and concentration-dependent decrease of topoisomerase I and its implication in camptothecin activity, Mol Pharmacol, 47, 907
Yang, 1996, A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases, Proc Natl Acad Sci USA, 93, 11534, 10.1073/pnas.93.21.11534
Pouliot, 1999, Yeast gene for a Tyr-DNA phosphodiesterase that repairs topo I covalent complexes, Science, in press
Sastry, 1998, Mechanisms for the processing of a prozen topoisomerase-DNA conjugate by human cell-free extracts, J Biol Chem, 273, 9942, 10.1074/jbc.273.16.9942
Squires, 1993, Hypersensitivity of Cockayne’s syndrome cells to camptothecins is associated with the generation of abnormally high levels of double strand breaks in nascent DNA, Cancer Res, 53, 2012
Fujimori, 1996, Acquired resistance of human breast cancer MCF-7/C4 cells with normal topoisomerase I and elevated DNA repair, Mol Pharmacol, 50, 1472
Shao, 1999, Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA: DNA-PK complexes, EMBO J, 18, 1397, 10.1093/emboj/18.5.1397
Eng, 1988, Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin, Mol Pharmacol, 34, 755
Nitiss, 1988, DNA topoisomerase-targeting antitumor drugs can be studied in yeast, Proc Natl Acad Sci USA, 85, 7501, 10.1073/pnas.85.20.7501
Smith, 1989, Enhanced sensitivity to camptothecin in ataxia telangiectasia cells and its relationship with the expression of DNA topoisomerase I, Int J Radiat Biol, 55, 217, 10.1080/09553008914550271
Jones, 1993, Cellular and chromosomal hypersensitivity to DNA crosslinking agents and topoisomerase inhibitors in the radiosensitive Chinese hamster irs mutants: phenotypic similarities to ataxia telangiectasia and Fanconi’s anaemia cells, Carcinogenesis, 14, 2487, 10.1093/carcin/14.12.2487
Tsao, 1992, The involvement of active DNA synthesis in camptothecin-induced G2 arrest: altered regulation of p34cdc2/cyclin B, Cancer Res, 52, 1823
Goldwasser, 1995, Topoisomerase I-related parameters and camptothecin activity in the colon cell lines from the National Cancer Institute anticancer screen, Cancer Res, 55, 2116
Gupta, 1997, Inactivation of p53 increases the cytotoxicity of camptothecin in human colon HCT116 and breast MCF-7 cancer cells, Clin Cancer Res, 3, 1653
Shao, 1997, Abrogation of an S-phase checkpoint and potentiation of camptothecin cytotoxicity by 7-hydroxystaurosporine (UCN-01) in human cancer cell lines, possibly influenced by p53, Cancer Res, 57, 4029
Shimizu, 1998, Lamin B phosphorylation by protein kinase Calpha and proteolysis during apoptosis in human leukemia HL60 cells, J Biol Chem, in press
Samejima, 1999, Caspase-mediated cleavage of DNA topoisomerase I at unconventional sites during apoptosis, J Biol Chem, 274, 4335, 10.1074/jbc.274.7.4335
Nieves-Neira, 1999, Apoptotic response to camptothecin and 7-hydroxystaurosporine (UCN-01) in the eight human breast cancer cell lines of the NCI anticancer drug screen: multifactorial relationship with topoisomerase I, protein kinase C, bcl-2 and caspase pathways, Int J Cancer, 82, 396, 10.1002/(SICI)1097-0215(19990730)82:3<396::AID-IJC13>3.0.CO;2-Z
Walton, 1993, Constitutive expression of human Bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis, Cancer Res, 53, 1853
Rubin, 1994, Identification of a mutant human topoisomerase I with intact catalytic and resistance to 9-nitro-camptothecin, J Biol Chem, 269, 2433, 10.1016/S0021-9258(17)41964-8
Li, 1997, Involvement of amino acids 361 to 364 of human topoisomerase I in camptothecin resistance and enzyme catalysis, Biochem Pharmacol, 53, 1019, 10.1016/S0006-2952(96)00899-4
Benedetti, 1993, Camptothecin resistance from a single mutation changing glycine 363 of human DNA topoisomerase I to cysteine, Cancer Res, 53, 4343
Tanizawa, 1992, Topoisomerase I alteration in a camptothecin-resistant cell line derived from chinese hamster DC3F cells in culture, Cancer Res, 52, 1848
Tanizawa, 1993, Cloning of Chinese Hamster DNA topoisomerase I cDNA and identification of a single point mutation responsible for camptothecin resistance, J Biol Chem, 268, 25463, 10.1016/S0021-9258(19)74414-7
Tamura, 1991, Molecular cloning of a cDNA of a camptothecin-resistant human DNA topoisomerase I and identification of mutation sites, Nucleic Acids Res, 19, 69, 10.1093/nar/19.1.69
Kubota, 1992, Detection of topoisomerase I gene point mutation in CPT-11 resistant lung cancer cell line, Biochem Biophys Res Commun, 188, 571, 10.1016/0006-291X(92)91094-7
Wang, 1997, Identification of mutations of DNA topoisomerase I response for camptothecin resistance, Cancer Res, 57, 1516
Knab, 1993, Mechanisms of camptothecin resistance in Yeast DNA topoisomerase I mutants, J Biol Chem, 268, 22322, 10.1016/S0021-9258(18)41531-1
Beidler, 1995, Camptothecin resistance involving steps subsequent to the formation of protein-linked DNA breaks in human camptothecin-resistant KB cell lines, Cancer Res, 56, 345
Lebel, 1998, A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of proliferative capacity, Proc Natl Acad Sci USA, 95, 13097, 10.1073/pnas.95.22.13097
Poot, 1999, Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase, Hum Genet, 104, 10, 10.1007/s004390050903
Kraakman-van der Zwet, 1999, Immortalization and characterization of Nijmegen Breakage syndrome fibroblasts, Mutat Res, 434, 17, 10.1016/S0921-8777(99)00009-9
Barrows, 1998, The CHO XRCC1 mutant, EM9, deficient in DNA ligase III activity, exhibits hypersensitivity to camptothecin independent of DNA replication, Mutat Res, 408, 103, 10.1016/S0921-8777(98)00022-6
Thacker, 1990, DNA-break repair, radioresistance of DNA synthesis, and camptothecin sensitivity in the radiation-sensitive irs mutants: comparisons to ataxia-telangiectasia cells, Mutat Res, 235, 49, 10.1016/0921-8777(90)90057-C
Caldecott, 1991, Cross-sensitivity of gamma-ray-sensitive hamster mutants to cross-linking agents, Mutat Res, 255, 111, 10.1016/0921-8777(91)90046-R
Johnson, 1999, Targeting double-strand breaks to replicating DNA identifies a subpathway of DSB repair that is defective in ataxiatelangiectasia cells, Biochem Biophys Res Commun, 261, 317, 10.1006/bbrc.1999.1024
Chatterjee, 1989, Camptothecin hypersensitivity in poly(adenosine diphosphate-ribose) polymerase-deficient cell lines, Cancer Commun, 1, 389, 10.3727/095535489820875129
Hinz, 1994, Pharmacokinetics of the in vivo and in vitro conversion of 9-nitro-20-(S)-camptothecin to 9-amino-20(S)-camptothecin in humans, dogs, and mice, Cancer Res, 54, 3096