Topical transfection using plasmid DNA in a water-in-oil nanoemulsion

Alexander, 1995, Liposome-mediated gene transfer and expression via the skin, Hum. Mol. Genet., 4, 2279, 10.1093/hmg/4.12.2279 Alexander, 1991, Physical methods of gene delivery using keratinocytes as a target for somatic cell gene therapy, Proc. Natl. Acad., 88, 2726 Bolzinger, 1998, Bicontinuous sucrose ester nanoemulsion: a new vehicle for topical delivery of niflumic acid, Int. J. Pharmacol., 176, 39, 10.1016/S0378-5173(98)00292-0 Chung, 1998, Apoptosis in the pathogenesis of cutaneous lupus erythematosus, Am. J. Dermatopathol., 20, 233, 10.1097/00000372-199806000-00002 Constantinides, 1995, Enhanced intestinal absorption of an RGD peptide from water-in-oil nanoemulsions of different composition and size, J. Control Release, 34, 109, 10.1016/0168-3659(94)00129-I Constantinides, 1996, Water-in-Oil nanoemulsions containing medium-chain fatty acids/salts: formulation and intestinal absorption enhancement evaluation, Pharmacol. Res., 13, 210, 10.1023/A:1016030812272 Fan, 1999, Immunization via hair follicles by topical application of naked DNA to normal skin, Nat. Biotechnol., 17, 870, 10.1038/12856 Foreman, 1997, J. Clin. Invest., 99, 2971, 10.1172/JCI119492 Ghazizadeh, 1998, The skin as a vehicle for gene therapy, 1 Jaworsky, 1997, Connective Tissue Diseases, 253 Li, 1995, The feasibility of targeted selective gene therapy of the hair follicle, Nat. Med., 1, 705, 10.1038/nm0795-705 Nicolas, 1990, Response of discoid and subacute cutaneous lupus erythematosus to recombinant interferon alpha 2A, J. Invest. Dermatol., 95, 142S, 10.1111/1523-1747.ep12875049 Niemiec, 1997, Perifollicular transgenic expression of human interleukin-1 receptor antagonist protein following topical application of novel liposome-plasmid DNA formulations in vivo, J. Pharmacol. Sci., 86, 701, 10.1021/js9604873 Nuovo, 1994, 54 Osborne, 1988, Alcohol free nanoemulsions, J. Disp. Sci. Technol., 9, 415, 10.1080/01932698808943999 Osborne, 1991, Nanoemulsions as topical drug delivery vehicles: in-vitro transdermal studies of a model hydrophilic drug, J. Pharm. Pharmacol., 43, 451, 10.1111/j.2042-7158.1991.tb03511.x Raczka, 1998, The effect of synthetic surfactant exosurf on gene transfer in mouse lung in vivo, Gene Ther., 5, 1333, 10.1038/sj.gt.3300752 Rakhmilevich, 1996, Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors, Proc. Natl. Acad. Sci. USA, 93, 6291, 10.1073/pnas.93.13.6291 Sambrook, 1989, 142 Sant, 1998, Molecular lysis of synovial lining cells by in vivo herpes simplex virus-thymidine kinase gene transfer, Hum. Gene Ther., 9, 2735, 10.1089/hum.1998.9.18-2735 Thivolet, 1990, Recombinant interferon α2a is effective in the treatment of discoid and subacute cutaneous lupus erythematosus, Br. J. Dermatol., 122, 405, 10.1111/j.1365-2133.1990.tb08290.x Yarosh, 1996, The role of liposomal delivery in cutaneous DNA repair, Adv. Drug Delivery Rev., 18, 325, 10.1016/0169-409X(95)00079-M Yu, 1999, Topical gene delivery to murine skin, J. Invest. Dermatol., 112, 370, 10.1046/j.1523-1747.1999.00513.x