Topical application of solubilized Reseda luteola extract reduces ultraviolet B-induced inflammation in vivo

F. Casetti1, W. Jung1, U. Wölfle1, J. Reuter1, K. Neumann2, B. Gilb3, A. Wähling4, S. Wagner5, I. Merfort5, C.M. Schempp1
1Competence Center skintegral, University Medical Center Freiburg, Germany
2Institute of Medical Biometry, Charité, Humboldt University Berlin, Germany
3HWI Analytik, Rheinzabern, Germany
4NIG Nahrungs- Ingenieurtechnik, Magdeburg, Germany
5Institute of Pharmaceutical Sciences, Department of Pharmaceutical Biology and Biotechnology, University of Freiburg, Germany

Tài liệu tham khảo

Seelinger, 2008, Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin, Planta Med, 74, 1667, 10.1055/s-0028-1088314 Havsteen, 2002, The biochemistry and medical significance of the flavonoids, Pharmacol Ther, 96, 67, 10.1016/S0163-7258(02)00298-X Heim, 2002, Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships, J Nutr Biochem, 13, 572, 10.1016/S0955-2863(02)00208-5 Seelinger, 2008, Anti-carcinogenic effects of the flavonoid luteolin, Molecules, 13, 2628, 10.3390/molecules13102628 Lin, 2008, Luteolin, a flavonoid with potential for cancer prevention and therapy, Curr Cancer Drug Targets, 8, 634, 10.2174/156800908786241050 Tsuji, 2008, Cytotoxic effects of the dietary flavones chrysin and apigenin in a normal trout liver cell line, Chem Biol Interact, 171, 37, 10.1016/j.cbi.2007.08.007 Samy, 2006, Anti-tumor promoting potential of luteolin against 7, 12-dimethylbenz(a)anthracene-induced mammary tumors in rats, Chem Biol Interact, 164, 1, 10.1016/j.cbi.2006.08.018 Kimata, 2000, Effects of luteolin, quercetin and baicalein on immunoglobulin E-mediated mediator release from human cultured mast cells, Clin Exp Allergy, 30, 501, 10.1046/j.1365-2222.2000.00768.x Kimata, 2000, Effects of luteolin and other flavonoids on IgE-mediated allergic reactions, Planta Med, 66, 25, 10.1055/s-2000-11107 Ziyan, 2007, Evaluation of the anti-inflammatory activity of luteolin in experimental animal models, Planta Med, 73, 221, 10.1055/s-2007-967122 Wang, 2007, Effect of luteolin on COX-2 and mPGES-1 expression in LPS-induced RAW264.7 cells, Zhong Yao Cai, 30, 1263 Chen, 2007, Luteolin suppresses inflammation-associated gene expression by blocking NF-kappaB and AP-1 activation pathway in mouse alveolar macrophages, Life Sci, 81, 1602, 10.1016/j.lfs.2007.09.028 Hu, 2004, Luteolin and luteolin-7-O-glucoside from dandelion flower suppress iNOS and COX-2 in RAW264.7 cells, Mol Cell Biochem, 265, 107, 10.1023/B:MCBI.0000044364.73144.fe Kim, 2003, Luteolin inhibits the nuclear factor-kappa B transcriptional activity in Rat-1 fibroblasts, Biochem Pharmacol, 66, 955, 10.1016/S0006-2952(03)00465-9 Horvathova, 2005, Protective effect of quercetin and luteolin in human melanoma HMB-2 cells, Mutat Res, 565, 105, 10.1016/j.mrgentox.2004.08.013 Merfort, 1994, In vivo skin penetration studies of camomile flavones, Pharmazie, 49, 509 Merfort, 1985, Flavonoids from Arnica montana and Arnica chamissonis, Planta Med, 51, 136, 10.1055/s-2007-969428 Yoshizaki, 1987, A chemotaxonomic study of flavonoids in the leaves of six Trichosanthes species, Phytochemistry, 26, 2557, 10.1016/S0031-9422(00)83876-5 Fitzpatrick, 1988, The validity and practicality of sun-reactive skin types I through VI, Arch Dermatol, 124, 869, 10.1001/archderm.1988.01670060015008 Jocher, 2005, The UV erythema test as a model to investigate the anti-inflammatory potency of topical preparations–reevaluation and optimization of the method, Skin Pharmacol Physiol, 18, 234, 10.1159/000086669 Juhlin, 1992, Effect of drugs on the early and late phase UV erythema, Acta Derm Venereol, 72, 222 Takiwaki, 1994, The degrees of UVB-induced erythema and pigmentation correlate linearly and are reduced in a parallel manner by topical anti-inflammatory agents, J Invest Dermatol, 103, 642, 10.1111/1523-1747.ep12398276 Gehring, 2003 Back, 2006, Can changes in hydrophobicity increase the bioavailability of alpha-tocopherol?, Eur J Nutr, 45, 1, 10.1007/s00394-005-0556-9 Saiki, 2008, Altered bacterial metabolism, not coenzyme Q content, is responsible for the lifespan extension in Caenorhabditis elegans fed an Escherichia coli diet lacking coenzyme Q, Aging Cell, 7, 291, 10.1111/j.1474-9726.2008.00378.x Saiki, 2008, Coenzyme Q10 supplementation rescues renal disease in Pdss2kd/kd mice with mutations in prenyl diphosphate synthase subunit 2, Am J Physiol Renal Physiol, 295, 1535, 10.1152/ajprenal.90445.2008