Toll-like receptors (TLRs) in aquatic animals: Signaling pathways, expressions and immune responses
Tóm tắt
Từ khóa
Tài liệu tham khảo
Magnadottir, 2006, Innate immunity of fish (overview), Fish Shellfish Immunol, 20, 137, 10.1016/j.fsi.2004.09.006
Rauta, 2012, Immune system and immune responses in fish and their role in comparative immunity study: a model for higher organisms, Immunol Lett, 148, 23, 10.1016/j.imlet.2012.08.003
Janeway, 1989, Evolution and revolution in immunology, Cold Spring Harbor Symp Quant Biol, 54, 1, 10.1101/SQB.1989.054.01.003
Kawai, 2011, Toll-like receptors and their crosstalk with other innate receptors in infection and immunity, Immunity, 34, 637, 10.1016/j.immuni.2011.05.006
O’Neill, 2013, The history of Toll-like receptors -redefining innate immunity, Nat Rev Immunol, 13, 453, 10.1038/nri3446
Gomez, 2013, The mucosal immune system of fish: The evolution of tolerating commensals while fighting pathogens, Fish Shellfish Immunol, 10.1016/j.fsi.2013.09.032
Tort, 2003, Fish immune system. A crossroads between innate and adaptive responses, Inmunologia, 22, 277
Bergman, 2011, Toll-like receptors (TLRs) and mannan-binding lectin (MBL): on constant alert in a hostile environment, Ups J Med Sci, 116, 90, 10.3109/03009734.2010.545494
Scapigliati, 2013, Functional aspects of fish lymphocytes, Dev Comp Immunol, 41, 200, 10.1016/j.dci.2013.05.012
Anderson, 1985, Establishment of dorsal-ventral polarity in the Drosophila embryo: the induction of polarity by the Toll gene product, Cell, 42, 791, 10.1016/0092-8674(85)90275-2
Lemaitre, 1996, The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults, Cell, 86, 973, 10.1016/S0092-8674(00)80172-5
Medzhitov, 1997, A human homologue of the Drosophila Toll protein signals activation of adaptive immunity, Nature, 388, 394, 10.1038/41131
Poltorak, 1998, Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene, Science, 282, 2085, 10.1126/science.282.5396.2085
Sangrador-Vegas, 2000, Cloning, characterization of the rainbow trout (Oncorhynchus mykiss) type IIinterleukin-1 receptor cDNA, Eur J Biochem, 267, 7031, 10.1046/j.1432-1327.2000.01800.x
Subramaniam, 2002, Cloning of a Salmo salar interleukin-1 receptor-like cDNA, Dev Comp Immunol, 26, 415, 10.1016/S0145-305X(01)00091-X
Scapigliati, 2004, Modelling of fish interleukin-1, its receptor, Dev Comp Immunol, 28, 429, 10.1016/j.dci.2003.09.014
Stafford, 2003, A toll-like receptor (TLR) gene that is up-regulated in activated goldfish macrophages, Dev Comp Immunol, 27, 685, 10.1016/S0145-305X(03)00041-7
Oshiumi, 2003, Prediction Of the prototype of the human Toll-like receptor gene family from the pufferfish, Fugu rubripes, genome, Immunogenetics, 54, 791, 10.1007/s00251-002-0519-8
Jault, 2004, Toll-like receptor gene family and TIR-domain adapters in Danio rerio, Mol Immunol, 40, 759, 10.1016/j.molimm.2003.10.001
Meijer, 2004, Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish, Mol Immunol, 40, 773, 10.1016/j.molimm.2003.10.003
Roach, 2005, The evolution of vertebrate Toll-like receptors, Proc Natl Acad Sci USA, 102, 9577, 10.1073/pnas.0502272102
Tauszig, 2000, Toll-related receptors and the control of antimicrobial peptide expression in Drosophila, Proc Natl Acad Sci USA, 97, 10520, 10.1073/pnas.180130797
Song, 2010, Bivalve immunity, 44
Franzenburg, 2012, MyD88-deficient Hydra reveal an ancient function of TLR signaling in sensing bacterial colonizers, Proc Natl Acad Sci USA, 109, 19374, 10.1073/pnas.1213110109
Song, 2012, The evolution and origin of animal toll-like receptor signaling pathway revealed by network-level molecular evolutionary analyses, Plos One, 7, e51657, 10.1371/journal.pone.0051657
Chuang, 2000, Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9, Eur Cytokine Netw, 11, 372
Du, 2000, Three novel mammalian toll-like receptors: gene structure, expression, and evolution, Eur Cytokine Netw, 11, 362
Tabeta, 2004, Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalo virus infection, Proc Natl Acad Sci USA, 101, 3516, 10.1073/pnas.0400525101
Beutler, 2002, Evolution of the TIR, Tolls and TLRs: functional inferences from computational biology, Curr Top Microbiol Immunol, 270, 1
Hughes, 2008, Functional diversification of the toll like receptor gene family, Immunogenetics, 60, 249, 10.1007/s00251-008-0283-5
Kruithof, 2007, Gene conversion limits divergence of mammalian TLR1 and TLR6, BMC Evol Biol, 7, 148, 10.1186/1471-2148-7-148
Triantafilou, 2005, TLR8 and TLR7 are involved in the host's immune response to human parechovirus 1, Eur J Immunol, 35, 2416, 10.1002/eji.200526149
Palti, 2010, Identification, characterization and genetic mapping of TLR7, TLR (a1 and TLR8a2 genes in rainbow trout (Oncorhynchus mykiss), Dev Comp Immunol, 34, 219, 10.1016/j.dci.2009.10.002
Hibino, 2006, The immune gene repertoire encoded in the purple sea urchin genome, Dev Biol, 300, 349, 10.1016/j.ydbio.2006.08.065
Zhang, 2010, Domain architecture evolution of pattern-recognition receptors, Immunogenetics, 62, 263, 10.1007/s00251-010-0428-1
Huang, 2008, Genomic analysis of the immune gene repertoire of amphioxus releals extraordinary innate complexity and diversity, Genome Res, 18, 1112, 10.1101/gr.069674.107
Ishii, 2007, Phylogenetic and expression analysis of amphibian Xenopus Toll-like receptors, Immunogenetics, 59, 281, 10.1007/s00251-007-0193-y
Ishii, 2007, Lamprey TLRs with properties distinct from those of the variable lymphocyte receptors, J Immunol, 178, 397, 10.4049/jimmunol.178.1.397
Rebl, 2010, Toll-like receptor signaling in bony fish, Vet Immunol Immunopathol, 134, 139, 10.1016/j.vetimm.2009.09.021
Yali, 2013, Two adaptor molecules of MyD88 and TRAF6 in Apostichopus japonicas Toll signaling cascade: molecular cloning and expression analysis, Dev Comp Immunol, 41, 498, 10.1016/j.dci.2013.07.009
Tsujita, 2004, Sensing bacterial flagellin by membrane and soluble orthologs of Toll-like receptor 5 in rainbow trout (Onchorhynchus mikiss), J Biol Chem, 279, 48588, 10.1074/jbc.M407634200
LeBouder, 2003, Soluble forms of Toll-like receptor (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milk, J Immunol, 171, 6680, 10.4049/jimmunol.171.12.6680
Iwami, 2000, Cutting edge: naturally occurring soluble form of mouse Toll-like receptor 4 inhibits lipopolysaccharide signaling, J Immunol, 165, 6682, 10.4049/jimmunol.165.12.6682
O’Neill, 2003, The toll-IL-1 receptor adaptor family grows to five members, Trends Immunol, 24, 286, 10.1016/S1471-4906(03)00115-7
O’Neill, 2007, The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling, Nat Rev Immunol, 7, 353, 10.1038/nri2079
Kenny, 2008, Signalling adaptors used by Toll-like receptors: an update, Cytokine, 43, 342, 10.1016/j.cyto.2008.07.010
Adachi, 1998, Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function, Immunity, 9, 143, 10.1016/S1074-7613(00)80596-8
Lin, 2010, Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling, Nature, 465, 885, 10.1038/nature09121
Sun, 2004, The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes, Mol Cell, 14, 289, 10.1016/S1097-2765(04)00236-9
Keating, 2007, IRAK-2 participates in multiple Toll-like receptor signaling pathways to NF-κB via activation of TRAF6 ubiquitination, J Biol Chem, 282, 33435, 10.1074/jbc.M705266200
Kanayama, 2004, TAB2 and TAB3 activate the NF-κB pathway through binding to polyubiquitin chains, Mol Cell, 15, 535, 10.1016/j.molcel.2004.08.008
Horng, 2002, The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors, Nature, 420, 329, 10.1038/nature01180
Heil, 2004, Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8, Science, 303, 1526, 10.1126/science.1093620
Yamamoto, 2003, TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway, Nat Immunol, 4, 1144, 10.1038/ni986
Palsson-McDermott, 2013, TAG: a GOLD domain-containing splice variant of TRAM that negatively regulates the MyD88-independent pathway in TLR4 signaling, Nat Immunol, 10, 579, 10.1038/ni.1727
Nakamoto, 2012, Virus recognition by Toll-7 activates antiviral autophagy in Drosophila, Immunity, 36, 658, 10.1016/j.immuni.2012.03.003
Cervantes, 2012, TLR8: the forgotten relative revindicated, Cell Mol Immunol, 9, 434, 10.1038/cmi.2012.38
Doyle, 2002, IRF3 mediates a TLR3/TLR4-specific antiviral gene program, Immunity, 17, 251, 10.1016/S1074-7613(02)00390-4
Schoenemeyer, 2005, The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling, J Biol Chem, 280, 17005, 10.1074/jbc.M412584200
Costa-Mattioli, 2008, RAPping production of type I interferon in pDCs through mTOR, Nat Immunol, 9, 1097, 10.1038/ni1008-1097
Palti, 2011, Toll-like receptors in bony fish: from genomics to function, Dev Comp Immunol, 35, 1263, 10.1016/j.dci.2011.03.006
Yang, 2010, Molecular identification and expression analysis of Toll-like receptor 3 in common carp Cyprinus carpio, J Fish Biol, 76, 1926, 10.1111/j.1095-8649.2010.02624.x
Tanekhy, 2010, Cloning, characterization, and expression analysis of Toll-like receptor-7 cDNA from common carp, Cyprinus carpio L, Comp Biochem Physiol D Genomics Proteomics, 5, 245, 10.1016/j.cbd.2010.07.001
Sullivan, 2009, The gene history of zebrafish TLR 4a and TLR4b is predictive of their divergent functions, J Immunol, 183, 5896, 10.4049/jimmunol.0803285
Fearon, 1996, The instructive role of innate immunity in the acquired immune response, Science, 272, 50, 10.1126/science.272.5258.50
Cook, 2004, Toll-like receptors in the pathogenesis of human disease, Nat Immunol, 5, 975, 10.1038/ni1116
Sabroe, 2003, Toll-like receptors in health and disease: complex questions remain, J Immunol, 171, 1630, 10.4049/jimmunol.171.4.1630
Agnese, 2002, Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of Gram-negative infections, J Infect Dis, 186, 1522, 10.1086/344893
Kiechl, 2002, Toll-like receptor 4 polymorphisms and atherogenesis, N Engl J Med, 347, 185, 10.1056/NEJMoa012673
Reindl, 2003, Mutations in the gene for toll-like receptor 4 and multiple sclerosis, Tissue Antigens, 61, 85, 10.1034/j.1399-0039.2003.610108.x
Takeuchi, 2001, Discrimination of bacterial lipoproteins by Toll-like receptor 6, Int Immunol, 13, 933, 10.1093/intimm/13.7.933
Hirschfeld, 2001, Signaling by toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages, Infect Immun, 69, 1477, 10.1128/IAI.69.3.1477-1482.2001
Tanji, 2013, Structural reorganization of the Toll-Like receptor 8 dimer induced by agonistic ligands, Science, 339, 1426, 10.1126/science.1229159
Basu, 2012, Inductive expression of toll-like receptor 5 (TLR5) and associated downstream signaling molecules following ligand exposure and bacterial infection in the Indian major carp, mrigal (Cirrhinus mrigala), Fish Shellfish Immunol, 32, 121, 10.1016/j.fsi.2011.10.031
Werts, 2001, Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism, Nat Immunol, 2, 346, 10.1038/86354
Lund, 2003, Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasma cytoid dendritic cells, J Exp Med, 198, 513, 10.1084/jem.20030162
Lin, 2007, Acute phase response in zebrafish upon Aeromonas salmonicida and Staphylococcus aureus infection: striking similarities and obvious differences with mammals, Mol Immunol, 44, 295, 10.1016/j.molimm.2006.03.001
Sepulcre, 2007, The activation of gilthead sea bream professional phagocytes by different PAMPs underlines the behavioral diversity of the main innate immune cells of bony fish, Mol Immunol, 44, 2009, 10.1016/j.molimm.2006.09.022
Lischke, 2000, Isolation and characterization of glycosylphosphatidylinositol-anchored, mucin-like surface glycoproteins from bloodstream forms of the freshwater-fish parasite Trypanosoma carassii, Biochem J, 345, 693, 10.1042/0264-6021:3450693
Pietretti, 2013, Ligand specificities of Toll-like receptors in fish: indications from infection studies, Dev Comp Immunol
Hemmrich, 2007, The evolution of immunity: a low-life perspective, Trends Immunol, 28, 449, 10.1016/j.it.2007.08.003
Dunn, 2009, Immunorecognition and immunoreceptors in the Cnidaria, Inv Surv J, 6, 7
Miller, 2007, The innate immune repertoire in Cnidaria – ancestral complexity and stochastic gene loss, Genome Biol, 8, R59, 10.1186/gb-2007-8-4-r59
Augustin, 2010, How Hydra senses and destroys microbes, Semin Immunol, 22, 54, 10.1016/j.smim.2009.11.002
Bosch, 2009, Uncovering evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence, Dev Comp Immunol, 33, 559, 10.1016/j.dci.2008.10.004
Zheng, 2005, Toll-like receptors in invertebrate innate immunity, Inv Surv J, 2, 105
Putnam, 2007, Sea anemone genome reveals ancestral eumetazoan gene repertoire and genomic organization, Science, 317, 86, 10.1126/science.1139158
Sullivan, 2007, Rel homology domain-containing transcription factors in the cnidarian Nematostella vectensis, Dev Genes Evol, 217, 63, 10.1007/s00427-006-0111-6
Schwarz, 2008, Coral life history and symbiosis: functional genomic resources for two reef building Caribbean corals, Acropora palmata and Montastraea faveolata, BMC Genomics, 9, 97, 10.1186/1471-2164-9-97
Davidson, 2008, Toll-like receptor genes (TLRs) from Capitella capitata and Helobdella robusta (Annelida), Dev Comp Immunol, 35, 214
Cuvillier-Hot, 2011, Characterization and immune function of two intracellular sensors, HmTLR1 and HmNLR, in injured CNS of an invertebrate, Dev Comp Immunol, 35, 214, 10.1016/j.dci.2010.09.011
Skanta, 2013, Molecular cloning and expression of TLR in the Eisenia andrei earthworm, Dev Comp Immunol, 41, 694, 10.1016/j.dci.2013.08.009
Qiu, 2007, Molecular cloning and expression of a Toll receptor gene homologue from Zhikong Scallop, Chlamys farreri, Fish Shellfish Immunol, 22, 451, 10.1016/j.fsi.2006.05.003
Qiu, 2007, Identification and characterization of a myeloid differentiation factor 88 (MyD88) cDNA from Zhikong scallop Chlamys farreri, Fish Shellfish Immunol, 23, 614, 10.1016/j.fsi.2007.01.012
Qiu, 2009, Identification and expression of TRAF6 (TNF receptor-associated factor 6) gene in Zhikong Scallop Chlamys farreri, Fish Shellfish Immunol, 26, 359, 10.1016/j.fsi.2008.10.010
Wang, 2011, A primitive Toll-like receptor signaling pathway in mollusk Zhikong scallop Chlamys farreri, Dev Comp Immunol, 35, 511, 10.1016/j.dci.2010.12.005
Zhang, 2011, A Crassostrea gigas Toll like receptor and comparative analysis of TLR pathway in invertebrates, Fish Shellfish Immunol, 30, 560, 10.1016/j.fsi.2010.12.023
Mateo, 2010, Differential gene expression of γ-actin, Toll-like receptor 2 (TLR-2) and interleukin-1 receptor-associated kinase 4 (IRAK-4) in Mya arenaria haemocytes induced by in vivo infections with two Vibrio splendidus strains, Dev Comp Immunol, 34, 710, 10.1016/j.dci.2010.02.006
Yang, 2008, A Toll receptor from Chinese shrimp Fenneropenaeus chinensis is responsive to Vibrio anguillarum infection, Fish Shellfish Immunol, 24, 564, 10.1016/j.fsi.2007.12.012
Mekata, 2008, Identification of cDNA encoding Toll receptor, MjToll gene from kuruma shrimp, Marsupenaeus japonicus, Fish Shellfish Immunol, 24, 122, 10.1016/j.fsi.2007.10.006
Wang, 2012, Molecular cloning, characterization and expression analysis of two novel Tolls (LvToll2 and LvToll3) and three putative Spatzle-like Toll ligands (LvSpz1-3) from Litopenaeus vannamei, Dev Comp Immunol, 36, 359, 10.1016/j.dci.2011.07.007
Buckley, 2007, Extraordinary diversity among members of the large gene family, 185/333, from the purple sea urchin, Strongylocentrotus purpuratus, BMC Mol Biol, 8, 68, 10.1186/1471-2199-8-68
Buckley, 2008, The 185/333 gene family is a rapidly diversifying host-defense gene cluster in the purple sea urchin Strongylocentrotus purpuratus, J Mol Biol, 379, 912, 10.1016/j.jmb.2008.04.037
Pancer, 1999, Origins of immunity: transcription factors and homologues of effector genes of the vertebrate immune system expressed in sea urchin coelomocytes, Immunogenetics, 49, 773, 10.1007/s002510050551
Lu, 2013, Two adaptor molecules of MyD88 and TRAF6 in Apostichopus japonicus Toll signaling cascade: molecular cloning and expression analysis, Dev Comp Immunol, 41, 498, 10.1016/j.dci.2013.07.009
Yuan, 2009, An amphioxus TLR with dynamic embryonic expression pattern responses to pathogens and activates NF-kB pathway via MyD88, Mol Immunol, 46, 2348, 10.1016/j.molimm.2009.03.022
Davidson, 2002, A molecular analysis of ascidian metamorphosis reveals activation of an innate immune response, Development, 129, 4739, 10.1242/dev.129.20.4739
Azumi, 2003, Genomic analysis of immunity in a Urochordate and the emergence of the vertebrate immune system: waiting for Godot, Immunogenetics, 55, 570, 10.1007/s00251-003-0606-5
Denoeud, 2010, Plasticity of animal genome architecture unmasked by rapid evolution of a pelagic tunicate, Science, 330, 1381, 10.1126/science.1194167
Sasaki, 2009, Toll-like receptors of the Ascidian Ciona intestinalis: prototypes with hybrid functionalities of vertebrate toll-like receptors, J Biol Chem, 284, 27336, 10.1074/jbc.M109.032433
Pancer, 2004, Somatic diversification of variable lymphocyte receptors in the agnathan sea lamprey, Nature, 430, 174, 10.1038/nature02740
Kasamatsu, 2010, Phylogenetic and expression analysis of lamprey toll-like receptors, Dev Comp Immunol, 34, 855, 10.1016/j.dci.2010.03.004
Wu, 2011, Comparative and phylogenetic analyses of three TIR domain containing adaptors in metazoans: implications for evolution of TLR signaling pathways, Dev Comp Immunol, 35, 764, 10.1016/j.dci.2011.02.009
Anandhakumar, 2012, Expression profile of toll-like receptor 2 mRNA in selected tissues of shark (Chiloscyllium sp.), Fish Shellfish Immunol, 33, 1174, 10.1016/j.fsi.2012.09.007
Sepulcre, 2009, Evolution of Lipopolysaccharide (LPS) recognition and signaling: fish TLR4 does not recognize LPS and negatively regulates NF-κB activation, J Immunol, 182, 1836, 10.4049/jimmunol.0801755
Kongchum, 2011, Molecular cloning, characterization and expression analysis of TLR9, MyD88 and TRAF6 genes in common carp (Cyprinus carpio), Fish Shellfish Immunol, 30, 361, 10.1016/j.fsi.2010.11.012
Quiniou, 2013, Comprehensive survey and genomic characterization of Toll-like receptors (TLRs) in channel catfish, Ictaluruspunctatus: identification of novel fish TLRs, Immunogenetics, 65, 511, 10.1007/s00251-013-0694-9
Tsujita, 2006, Fish soluble Toll-like receptor (TLR)5 amplifies human TLR5 response via physical binding to flagellin, Vaccine, 24, 2193, 10.1016/j.vaccine.2005.11.003
Tsoi, 2006, Identification of a transcript encoding a soluble form of toll-like receptor 5 (TLR5) in Atlantic salmon during Aeromonas salmonicida infection, Vet Immunol Immunopathol, 109, 183, 10.1016/j.vetimm.2005.05.013
Baoprasertkul, 2007, Divergent toll-like receptors in catfish (Ictalurus punctatus): TLR5S, TLR20, TLR21, Fish Shellfish Immunol, 23, 1218, 10.1016/j.fsi.2007.06.002
Bilodeau, 2005, Activation of TLR3 and TLR5 in channel catfish exposed to virulent Edwardsiella ictaluri, Dev Comp Immunol, 29, 713, 10.1016/j.dci.2004.12.002
Basu, 2012, Induction of toll-like receptor (TLR) 2, and MyD88-dependent TLR- signaling in response to ligand stimulation and bacterial infections in the Indian major carp, mrigal (Cirrhinus mrigala), Mol Biol Rep, 39, 6015, 10.1007/s11033-011-1415-9
Vander Sar, 2006, MyD88 innate immune function in a zebrafish embryo infection model, Infect Immun, 74, 2341
Takano, 2006, Identification, characterization of a myeloid differentiation factor 88 (MyD88) cDNA and gene in Japanese flounder, Paralichthys olivaceus, Dev Comp Immunol, 30, 807, 10.1016/j.dci.2005.11.003
Yazawa, 2005, Functional analysis of tumor necrosis factor gene promoter from Japanese flounder, Paralichthys olivaceus, using fish cell lines, Dev Comp Immunol, 29, 73, 10.1016/j.dci.2004.06.002
Phelan, 2005, Functional characterization of full-length TLR3, IRAK-4, and TRAF6 in Zebrafish (Danio rerio), Mol Immunol, 42, 1057, 10.1016/j.molimm.2004.11.005
Swain, 2011, Molecular characterization, inductive expression and mechanism of interleukin-10 gene induction in the Indian major carp, Catla (Catla catla), Aquacult Res, 43, 897, 10.1111/j.1365-2109.2011.02904.x
Samanta, 2012, Molecular characterization of toll-like receptor 2 (TLR2), analysis of its inductive expression and associated down-stream signaling molecules following ligands exposure and bacterial infection in the Indian major carp, rohu (Labeo rohita), Fish Shellfish Immunol, 32, 411, 10.1016/j.fsi.2011.11.029
Samanta, 2012, Molecular cloning and characterization of toll-like receptor 3, and inductive expression analysis of type I IFN, Mx and pro-inflammatory cytokines in the Indian carp, rohu (Labeo rohita), Mol Biol, 40, 225
Basu, 2013, Toll-like receptor (TLR) 4 in mrigal (Cirrhinus mrigala): response to lipopolysaccharide treatment and Aeromonas hydrophila infection, Int Res J Biol Sci, 2, 20
Armstrong, 1998, Conserved Spätzle/Toll signaling in dorsoventral patterning of Xenopus embryos, Mech Dev, 71, 99, 10.1016/S0925-4773(98)00003-3
Prothmann, 2000, The Toll/IL-1 receptor binding protein MyD88 is required for Xenopus axis formation, Mech Dev, 97, 85, 10.1016/S0925-4773(00)00447-0
Hennessy, 2010, Targeting of Toll-like receptors: emerging therapeutics, Nat Rev Drug Discov, 9, 293, 10.1038/nrd3203
Takeuchi, 2010, Pattern recognition receptors and inflammation, Cell, 140, 805, 10.1016/j.cell.2010.01.022
Iwasaki, 2010, Regulation of adaptive immunity by the innate immune system, Science, 327, 291, 10.1126/science.1183021
Wiens, 2007, Toll-like receptors are part of the innate immune defense system of sponges (demospongiae: Porifera), Mol Biol Evol, 24, 792, 10.1093/molbev/msl208
Limei, 2009, Identification and expression of TRAF6 (TNF receptor associated factor 6) gene in Zhikong Scallop Chlamys farreri, Fish Shellfish Immunol, 26, 359, 10.1016/j.fsi.2008.10.010
Rast, 2006, Genomic insights into the immune system of the sea urchin, Science, 314, 952, 10.1126/science.1134301
Wei, 2011, Cloning and expression of Toll-like receptors 1 and 2 from a teleost fish, the orange-spotted grouper Epinephelus coioides, Vet Immunol Immunopathol, 141, 173, 10.1016/j.vetimm.2011.02.016
Alexopoulou, 2001, Recognition of double stranded RNA and activation of NF-κB by Toll-like receptor 3, Nature, 413, 732, 10.1038/35099560
Matsuo, 2008, Teleost TLR22 recognizes RNA duplex to induce IFN and protect cells from Birna viruses, J Immunol, 181, 3474, 10.4049/jimmunol.181.5.3474
Kongchum, 2010, SNP discovery and development of genetic markers for mapping innate immune response genes in common carp (Cyprinus carpio), Fish Shellfish Immunol, 28, 918
Hayashi, 2001, The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5, Nature, 410, 1099, 10.1038/35074106
Diebold, 2004, Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA, Science, 303, 1529, 10.1126/science.1093616
Gorden, 2005, Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8, J Immunol, 174, 1259, 10.4049/jimmunol.174.3.1259
Latz, 2004, TLR9 signals after translocating from the ER to CpG DNA in the lysosome, Nat Immunol, 5, 190, 10.1038/ni1028
Rebl, 2007, Characterization of twin toll-like receptors from rainbow trout (Oncorhynchus mykiss): evolutionary relationship and induced expression by Aeromonas salmonicida salmonicida, Dev Comp Immunol, 31, 499, 10.1016/j.dci.2006.08.007