Toll-like receptor signaling is functional in immune cells of the endangered Tasmanian devil

Developmental & Comparative Immunology - Tập 53 - Trang 123-133 - 2015
Amanda L. Patchett1, Roger Latham2, Kate H. Brettingham-Moore2, Cesar Tovar1, A. Bruce Lyons2, Gregory M. Woods1,2
1Menzies Institute for Medical Research, University of Tasmania, Hobart, Tas, Australia
2School of Medicine, University of Tasmania, Hobart, Tas, Australia

Tài liệu tham khảo

Adams, 2012, Topical TLR7 agonist imiquimod can induce immune-mediated rejection of skin metastases in patients with breast cancer, Clin. Cancer Res., 18, 6748, 10.1158/1078-0432.CCR-12-1149 Applequist, 2002, Variable expression of Toll-like receptor in murine innate and adaptive immune cell lines, Int. Immunol., 14, 1065, 10.1093/intimm/dxf069 Banerjee, 2006, Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells, Proc. Natl. Acad. Sci. U. S. A., 103, 3274, 10.1073/pnas.0511113103 Basith, 2012, Roles of toll-like receptors in cancer: a double-edged sword for defense and offense, Arch. Pharm. Res., 35, 1297, 10.1007/s12272-012-0802-7 Bauer, 2001, Bacterial CpG-DNA triggers activation and maturation of human CD11c−, CD123+ dendritic cells, J. Immunol., 166, 5000, 10.4049/jimmunol.166.8.5000 Blander, 2004, Regulation of phagosome maturation by signals from toll-like receptors, Science, 304, 1014, 10.1126/science.1096158 Brown, 2011, Natural killer cell mediated cytotoxic responses in the Tasmanian devil, PLoS One, 6, e24475, 10.1371/journal.pone.0024475 Brozek, 1992, Proliferative responses of lymphocytes to mitogens in the gray, short-tailed opossum, Monodelphis domestica, Vet. Immunol. Immunopathol., 31, 11, 10.1016/0165-2427(92)90083-3 Casares, 2005, Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death, J. Exp. Med., 202, 1691, 10.1084/jem.20050915 Cowled, 2011, Molecular characterisation of Toll-like receptors in the black flying fox Pteropus alecto, Dev. Comp. Immunol., 35, 7, 10.1016/j.dci.2010.07.006 Cui, 2015, Diversity in the Toll-like receptor genes of the Tasmanian devil (Sarcophilus harrisii), Immunogenetics, 67, 195, 10.1007/s00251-014-0823-0 Cui, 2015, SNP marker discovery in koala TLR genes, PLoS One, 10, e0121068, 10.1371/journal.pone.0121068 Deakin, 2012, Genomic restructuring in the Tasmanian devil facial tumour: chromosome painting and gene mapping provide clues to evolution of a transmissible tumour, PLoS Genet., 8, e1002483, 10.1371/journal.pgen.1002483 Flies, 2014, Characterization of Toll-like receptors 1-10 in spotted hyenas, Vet. Res. Commun., 38, 165, 10.1007/s11259-014-9592-3 Galluzzi, 2012, Trial Watch: experimental Toll-like receptor agonists for cancer therapy, Oncoimmunology, 1, 699, 10.4161/onci.20696 Hamede, 2008, Seasonal, demographic and density-related patterns of contact between Tasmanian devils (Sarcophilus harrisii): Implications for transmission of devil facial tumour disease, Austral Ecol., 33, 614, 10.1111/j.1442-9993.2007.01827.x Hawkins, 2006, Emerging disease and population decline of an island endemic, the Tasmanian devil (Sarcophilus harrisii), Biol. Conserv., 131, 307, 10.1016/j.biocon.2006.04.010 He, 2007, TLR4 signaling promotes immune escape of human lung cancer cells by inducing immunosuppressive cytokines and apoptosis resistance, Mol. Immunol., 44, 2850, 10.1016/j.molimm.2007.01.022 Hemmi, 2002, Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway, Nat. Immunol., 3, 196, 10.1038/ni758 Hemmi, 2004, The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection, J. Exp. Med., 199, 1641, 10.1084/jem.20040520 Hornung, 2002, Quantitative expression of toll-like receptor 1–10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG Oligodeoxynucleotides, J. Immunol., 168, 4531, 10.4049/jimmunol.168.9.4531 Howson, 2014, Identification of dendritic cells, B cell and T cell subsets in Tasmanian devil lymphoid tissue; evidence for poor immune cell infiltration into devil facial tumors, Anat. Rec. (Hoboken), 297, 925, 10.1002/ar.22904 Inoue, 2014, Multimodal immunogenic cancer cell death as a consequence of anticancer cytotoxic treatments, Cell Death Differ., 21, 39, 10.1038/cdd.2013.84 Kaiser, 2013, Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL, J. Biol. Chem., 288, 31268, 10.1074/jbc.M113.462341 Kassianos, 2010, Isolation of human blood DC subtypes, Methods Mol. Biol., 595, 45, 10.1007/978-1-60761-421-0_3 Kreiss, 2015, Evidence for induction of humoral and cytotoxic immune responses against devil facial tumor disease cells in Tasmanian devils (Sarcophilus harrisii) immunized with killed cell preparations, Vaccine, 10.1016/j.vaccine.2015.01.039 Kreiss, 2011, Allorecognition in the Tasmanian devil (Sarcophilus harrisii), an endangered marsupial species with limited genetic diversity, PLoS One, 6, e22402, 10.1371/journal.pone.0022402 Kreiss, 2008, Assessment of cellular immune responses of healthy and diseased Tasmanian devils (Sarcophilus harrisii), Dev. Comp. Immunol., 32, 544, 10.1016/j.dci.2007.09.002 Kreiss, 2009, A histological and immunohistochemical analysis of lymphoid tissues of the Tasmanian devil, Anat. Rec. (Hoboken), 292, 611, 10.1002/ar.20896 Kreiss, 2009, The humoral immune response of the Tasmanian devil (Sarcophilus harrisii) against horse red blood cells, Vet. Immunol. Immunopathol., 130, 135, 10.1016/j.vetimm.2009.02.003 Krug, 2001, Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12, Eur. J. Immunol., 31, 3026, 10.1002/1521-4141(2001010)31:10<3026::AID-IMMU3026>3.0.CO;2-H Krutzik, 2005, TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells, Nat. Med., 11, 653, 10.1038/nm1246 Lehner, 2007, Efficient chemokine-dependent migration and primary and secondary IL-12 secretion by human dendritic cells stimulated through Toll-like receptors, J. Immunother., 30, 312, 10.1097/01.cji.0000211345.11707.46 Livak, 2001, Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method, Methods, 25, 402, 10.1006/meth.2001.1262 Loh, 2006, The immunohistochemical characterization of devil facial tumor disease (DFTD) in the Tasmanian Devil (Sarcophilus harrisii), Vet. Pathol., 43, 896, 10.1354/vp.43-6-896 Luo, 2012, Activation of Toll-like receptor 3 induces apoptosis of oral squamous carcinoma cells in vitro and in vivo, Int. J. Biochem. Cell Biol., 44, 1266, 10.1016/j.biocel.2012.04.025 McCallum, 2009, Transmission dynamics of Tasmanian devil facial tumor disease may lead to disease-induced extinction, Ecology, 90, 3379, 10.1890/08-1763.1 Medzhitov, 1997, A human homologue of the Drosophila Toll protein signals activation of adaptive immunity, Nature, 388, 394, 10.1038/41131 Medzhitov, 1998, MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways, Mol. Cell, 2, 253, 10.1016/S1097-2765(00)80136-7 Miconnet, 2002, CpG are efficient adjuvants for specific CTL induction against tumor antigen-derived peptide, J. Immunol., 168, 1212, 10.4049/jimmunol.168.3.1212 Murchison, 2012, Genome sequencing and analysis of the Tasmanian devil and its transmissible cancer, Cell, 148, 780, 10.1016/j.cell.2011.11.065 Murchison, 2010, The Tasmanian devil transcriptome reveals Schwann cell origins of a clonally transmissible cancer, Science, 327, 84, 10.1126/science.1180616 Napolitani, 2005, Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells, Nat. Immunol., 6, 769, 10.1038/ni1223 Ninomiya-Tsuji, 1999, The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway, Nature, 398, 252, 10.1038/18465 Obeid, 2007, Calreticulin exposure dictates the immunogenicity of cancer cell death, Nat. Med., 13, 54, 10.1038/nm1523 Paone, 2008, Toll-like receptor 3 triggers apoptosis of human prostate cancer cells through a PKC-alpha-dependent mechanism, Carcinogenesis, 29, 1334, 10.1093/carcin/bgn149 Pearse, 2006, Allograft theory: transmission of devil facial-tumour disease, Nature, 439, 549, 10.1038/439549a Pinfold, 2014, Mouse model of devil facial tumour disease establishes that an effective immune response can be generated against the Cancer cells, Front. Immunol., 5, 251, 10.3389/fimmu.2014.00251 Qian, 2001, IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFkappa B, J. Biol. Chem., 276, 41661, 10.1074/jbc.M102262200 Riccardi, 2006, Analysis of apoptosis by propidium iodide staining and flow cytometry, Nat. Protoc., 1, 1458, 10.1038/nprot.2006.238 Roach, 2005, The evolution of vertebrate Toll-like receptors, Proc. Natl. Acad. Sci. U. S. A., 102, 9577, 10.1073/pnas.0502272102 Schnare, 2001, Toll-like receptors control activation of adaptive immune responses, Nat. Immunol., 2, 947, 10.1038/ni712 Schon, 2003, Tumor-selective induction of apoptosis and the small-molecule immune response modifier imiquimod, J. Natl. Cancer Inst., 95, 1138, 10.1093/jnci/djg016 Schon, 2004, Death receptor-independent apoptosis in malignant melanoma induced by the small-molecule immune response modifier imiquimod, J. Invest Dermatol, 122, 1266, 10.1111/j.0022-202X.2004.22528.x Schwarz, 2003, Role of Toll-like receptors in costimulating cytotoxic T cell responses, Eur. J. Immunol., 33, 1465, 10.1002/eji.200323919 Siddle, 2013, Reversible epigenetic down-regulation of MHC molecules by devil facial tumour disease illustrates immune escape by a contagious cancer, Proc. Natl. Acad. Sci. U. S. A., 110, 5103, 10.1073/pnas.1219920110 Sohn, 2014, Imiquimod induces apoptosis of squamous cell carcinoma (SCC) cells via regulation of A20, PLoS One, 9, e95337, 10.1371/journal.pone.0095337 Song, 2011, Flagellin promotes the proliferation of gastric cancer cells via the Toll-like receptor 5, Int. J. Mol. Med., 28, 115 Tirumurugaan, 2010, Differential expression of toll-like receptor mRNA in selected tissues of goat (Capra hircus), Vet. Immunol. Immunopathol., 133, 296, 10.1016/j.vetimm.2009.08.015 Vacchelli, 2013, Trial Watch: toll-like receptor agonists for cancer therapy, Oncoimmunology, 2, e25238, 10.4161/onci.25238 Vahanan, 2008, Expression profile of toll like receptors in a range of water buffalo tissues (Bubalus bubalis), Vet. Immunol. Immunopathol., 126, 149, 10.1016/j.vetimm.2008.05.027 Vollmer, 2004, Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities, Eur. J. Immunol., 34, 251, 10.1002/eji.200324032 Warger, 2006, Synergistic activation of dendritic cells by combined Toll-like receptor ligation induces superior CTL responses in vivo, Blood, 108, 544, 10.1182/blood-2005-10-4015 Wilkinson, 1992, Isolation of koala lymphoid cells and their in vitro responses to mitogens, Vet. Immunol. Immunopathol., 31, 21, 10.1016/0165-2427(92)90084-4 Woods, 2007, The immune response of the Tasmanian Devil (Sarcophilus harrisii) and devil facial tumour disease, Ecohealth, 4, 338, 10.1007/s10393-007-0117-1 Xie, 2009, Toll-like receptor 2 mediates invasion via activating NF-kappaB in MDA-MB-231 breast cancer cells, Biochem. Biophys. Res. Commun., 379, 1027, 10.1016/j.bbrc.2009.01.009 Yamamoto, 2003, Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway, Science, 301, 640, 10.1126/science.1087262 Yamaoka, 1998, Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation, Cell, 93, 1231, 10.1016/S0092-8674(00)81466-X Zhu, 2008, Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: implications for vaccines, Proc. Natl. Acad. Sci. U. S. A., 105, 16260, 10.1073/pnas.0805325105