Toll-like receptor modulators: a patent review (2006 – 2010)

Sansonetti PJ, 2006, Nat Immunol, 7, 1237, 10.1038/ni1420

Akira S, 2006, Cell, 124, 783, 10.1016/j.cell.2006.02.015

10.2174/138161206778743466

Medzhitov R, 1997, Nature, 388, 394, 10.1038/41131

10.1006/bcmd.1998.0201

Rock FL, 1998, Proc Natl Acad Sci USA, 95, 588, 10.1073/pnas.95.2.588

Roach JC, 2005, Proc Natl Acad Sci USA, 102, 9577, 10.1073/pnas.0502272102

Rast JP, 2006, Science, 314, 952, 10.1126/science.1134301

Kawai T, 2010, Nat Immunol, 11, 373, 10.1038/ni.1863

O'Neill LA, 2003, Trends Immunol, 24, 286, 10.1016/S1471-4906(03)00115-7

Marshak-Rothstein A, 2006, Nat Rev Immunol, 6, 823, 10.1038/nri1957

Hennessy EJ, 2010, Nat Rev Drug Discov, 9, 293, 10.1038/nrd3203

Park BS, 2009, Nature, 458, 1191, 10.1038/nature07830

Liu L, 2008, Science, 320, 379, 10.1126/science.1155406

Jin MS, 2007, Cell, 130, 1071, 10.1016/j.cell.2007.09.008

Krishnan J, 2007, Exp Mol Med, 39, 421, 10.1038/emm.2007.47

Zhu J, 2009, Mol Immunol, 46, 978, 10.1016/j.molimm.2008.09.024

Honda K, 2004, Proc Natl Acad Sci USA, 101, 15416, 10.1073/pnas.0406933101

10.1038/ni1118

Pandey S, 2006, Immunol Cell Biol, 84, 333, 10.1111/j.1440-1711.2006.01444.x

Krishnan J, 2009, Arch Pharm Res, 32, 1485, 10.1007/s12272-009-2100-6

Romagne F, 2007, Drug Discov Today, 12, 80, 10.1016/j.drudis.2006.11.007

Agrawal S, 2007, Biochem Soc Trans, 35, 1461, 10.1042/BST0351461

Kanzler H, 2007, Nat Med, 13, 552, 10.1038/nm1589

Casella CR, 2008, Cell Mol Life Sci, 65, 3231, 10.1007/s00018-008-8228-6

Hughes AL, 2008, Immunogenetics, 60, 249, 10.1007/s00251-008-0283-5

Underhill DM, 1999, Nature, 401, 811, 10.1038/44605

Aliprantis AO, 1999, Science, 285, 736, 10.1126/science.285.5428.736

Brightbill HD, 1999, Science, 285, 732, 10.1126/science.285.5428.732

10.1016/j.smim.2006.12.002

Tapping RI, 2009, Semin Immunol, 21, 175, 10.1016/j.smim.2009.05.003

Eriksson EM, 2007, Curr Protein Pept Sci, 8, 412, 10.2174/138920307781369436

Moyle PM, 2008, Curr Med Chem, 15, 506, 10.2174/092986708783503249

Gallorini S, 2009, Proc Natl Acad Sci USA, 106, 17481, 10.1073/pnas.0903313106

Liang S, 2009, Vaccine, 27, 4302, 10.1016/j.vaccine.2009.05.027

Liu X, 2008, Vaccine, 26, 786, 10.1016/j.vaccine.2007.11.080

Simons MP, 2008, Urol Oncol, 26, 341, 10.1016/j.urolonc.2007.11.031

Murata M, 2008, Cancer Sci, 99, 1435, 10.1111/j.1349-7006.2008.00832.x

Guan Y, 2010, J Biol Chem, 285, 23755, 10.1074/jbc.M110.116046

Muzio M, 2000, J Immunol, 164, 5998, 10.4049/jimmunol.164.11.5998

Zarember KA, 2002, J Immunol, 168, 554, 10.4049/jimmunol.168.2.554

Sugiyama T, 2008, Int Immunol, 20, 1, 10.1093/intimm/dxm112

Salaun B, 2006, J Immunol, 176, 4894, 10.4049/jimmunol.176.8.4894

Panter G, 2009, Curr Opin Mol Ther, 11, 133

10.1016/j.vaccine.2009.01.071

10.1128/JVI.79.6.3350-3357.2005

Choe J, 2005, Science, 309, 581, 10.1126/science.1115253

Salem ML, 2006, Vaccine, 24, 5119, 10.1016/j.vaccine.2006.04.010

Tewari K, 2010, Vaccine, 28, 7256, 10.1016/j.vaccine.2010.08.098

Zheng R, 2008, Cancer Res, 68, 4045, 10.1158/0008-5472.CAN-07-6669

Longhi MP, 2009, J Exp Med, 206, 1589, 10.1084/jem.20090247

10.1016/S0952-7915(02)00013-4

Mata-Haro V, 2007, Science, 316, 1628, 10.1126/science.1138963

Krieg AM, 2007, Nat Biotechnol, 25, 303, 10.1038/nbt0307-303

D'souza G, 2007, N Engl J Med, 356, 1944, 10.1056/NEJMoa065497

D'Agostini C, 2005, Int Immunopharmacol, 5, 1205, 10.1016/j.intimp.2005.02.013

De Ridder M, 2006, Int J Radiat Oncol Biol Phys, 66, 1473, 10.1016/j.ijrobp.2006.07.1381

10.1586/14760584.5.5.617

Baldrick P, 2007, J Appl Toxicol, 27, 399, 10.1002/jat.1223

Butts C, 2005, J Clin Oncol, 23, 6674, 10.1200/JCO.2005.13.011

Andersen-Nissen E, 2007, J Exp Med, 204, 393, 10.1084/jem.20061400

Huleatt JW, 2008, Vaccine, 26, 201, 10.1016/j.vaccine.2007.10.062

Burdelya LG, 2008, Science, 320, 226, 10.1126/science.1154986

O'Neill LA, 2009, Pharmacol Rev, 61, 177, 10.1124/pr.109.001073

10.1038/sj.onc.1210906

Schon MP, 2008, Oncogene, 27, 190, 10.1038/sj.onc.1210913

Miller RL, 2008, Drug News Perspect, 21, 69, 10.1358/dnp.2008.21.2.1188193

Harrison LI, 2007, J Clin Pharmacol, 47, 962, 10.1177/0091270007303766

Dummer R, 2008, Clin Cancer Res, 14, 856, 10.1158/1078-0432.CCR-07-1938

Pockros PJ, 2007, J Hepatol, 47, 174, 10.1016/j.jhep.2007.02.025

Lee J, 2006, Proc Natl Acad Sci USA, 103, 1828, 10.1073/pnas.0510801103

Fletcher S, 2006, Curr Opin Investig Drugs, 7, 702

Kronenberger B, 2009, Ann Hepatol, 8, 103, 10.1016/S1665-2681(19)31786-7

Hemmi H, 2000, Nature, 408, 740, 10.1038/35047123

Airapetian A, 2004, Phys Rev Lett, 92, 012005, 10.1103/PhysRevLett.92.012005

Vollmer J, 2009, Adv Drug Deliv Rev, 61, 195, 10.1016/j.addr.2008.12.008

Goodchild A, 2009, J Biomol Screen, 14, 723, 10.1177/1087057109335325

Krieg AM, 2008, Oncogene, 27, 161, 10.1038/sj.onc.1210911

10.1586/14760584.8.3.293

Friedberg JW, 2009, Br J Haematol, 146, 282, 10.1111/j.1365-2141.2009.07773.x

Kochling J, 2008, Vaccine, 26, 4669, 10.1016/j.vaccine.2008.06.094

Dorn A, 2008, Curr Opin Mol Ther, 10, 10

Heijink IH, 2006, Pharmacol Ther, 112, 489, 10.1016/j.pharmthera.2006.05.005

Pastorelli L, 2009, Expert Opin Emerg Drugs, 14, 505, 10.1517/14728210903146882

10.1172/JCI25482

10.1615/CritRevImmunol.v23.i12.20

10.1084/jem.20050914

Asagiri M, 2008, Science, 319, 624, 10.1126/science.1150110

Rodriguez D, 2003, J Immunol, 171, 1001, 10.4049/jimmunol.171.2.1001

Liu X, 2008, Atherosclerosis, 196, 146, 10.1016/j.atherosclerosis.2007.03.025

Rezaei N, 2006, Int Immunopharmacol, 6, 863, 10.1016/j.intimp.2006.02.005

Gearing AJ, 2007, Immunol Cell Biol, 85, 490, 10.1038/sj.icb.7100102

Meng G, 2004, J Clin Invest, 113, 1473, 10.1172/JCI20762

Arslan F, 2008, Curr Pharm Des, 14, 1205, 10.2174/138161208784246090

Chang YC, 2009, FASEB J, 23, 3078, 10.1096/fj.09-129312

Spiller S, 2008, J Exp Med, 205, 1747, 10.1084/jem.20071990

Bennett-Guerrero E, 2007, Anesth Analg, 104, 378, 10.1213/01.ane.0000253501.07183.2a

Vanags D, 2006, Lancet, 368, 855, 10.1016/S0140-6736(06)69210-6

Broadley SA, 2009, Mult Scler, 15, 329, 10.1177/1352458508099141

Ii M, 2006, Mol Pharmacol, 69, 1288, 10.1124/mol.105.019695

Ledeboer A, 2007, Expert Opin Investig Drugs, 16, 935, 10.1517/13543784.16.7.935

Ungaro R, 2009, Am J Physiol Gastrointest Liver Physiol, 296, G1167, 10.1152/ajpgi.90496.2008

Vollmer J, 2005, J Exp Med, 202, 1575, 10.1084/jem.20051696

Christensen SR, 2006, Immunity, 25, 417, 10.1016/j.immuni.2006.07.013

Pascual V, 2006, Curr Opin Immunol, 18, 676, 10.1016/j.coi.2006.09.014

Barrat FJ, 2007, Eur J Immunol, 37, 3582, 10.1002/eji.200737815

Pawar RD, 2007, J Am Soc Nephrol, 18, 1721, 10.1681/ASN.2006101162

Parkinson T, 2008, Curr Opin Mol Ther, 10, 21

Govindaraj RG, 2010, PLoS One, 5, e12713, 10.1371/journal.pone.0012713

Manavalan B, 2010, PLoS One, 5, e15782, 10.1371/journal.pone.0015782

Sheedy FJ, 2008, Ann Rheum Dis, 67, iii50

Akira S, 2006, Curr Top Microbiol Immunol, 311, 1

Ishii KJ, 2004, Curr Opin Mol Ther, 6, 166

Rittirsch D, 2008, Nat Rev Immunol, 8, 776, 10.1038/nri2402

Lee HK, 2007, Mol Pharmacol, 72, 868, 10.1124/mol.107.038349

Toshchakov VY, 2007, J Immunol, 178, 2655, 10.4049/jimmunol.178.5.2655

Gilliet M, 2004, Arch Dermatol, 140, 1490, 10.1001/archderm.140.12.1490

Heil F, 2004, Science, 303, 1526, 10.1126/science.1093620

10.4049/jimmunol.177.10.6584

Uenishi Y, 2009, J Microbiol Methods, 77, 139, 10.1016/j.mimet.2009.01.019

Makkouk A, 2009, Immunopharmacol Immunotoxicol, 31, 331, 10.1080/08923970902802926

Kline JN, 2008, Drug News Perspect, 21, 434, 10.1358/dnp.2008.21.8.1272133

Wasan KM, 2008, Pharm Res, 25, 176, 10.1007/s11095-007-9428-8

Ledeboer A, 2006, Neuron Glia Biol, 2, 279, 10.1017/S1740925X0700035X