Toll-like receptor 2 (TLR2) mediates intracellular signalling in human keratinocytes in response to Malassezia furfur
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Ashbee HR, Evans EG (2002) Immunology of diseases associated with Malassezia species. Clin Microbiol Rev 15: 21–57
Baker BS, Ovigne JM, Powles AV, Corcoran S, Fry L (2003) Normal keratinocytes express Toll-like receptors (TLRs) 1, 2 and 5: modulation of TLR expression in chronic plaque psoriasis. Br J Dermatol 148: 670–679
Birchler T, Seibl R, Buchner K, Loeriger S, Seger R, Hossle JP, Aguzzi A, Lauener RP (2001) Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta defensin-2 in response to bacterial lipoprotein. Eur J Immunol 31: 3131–3137
Bos JD (1997) The skin as an organ of immunity. Clin Exp Immnunol 107: 3–5
Bowcock AM, Shannon W, Du F, Duncan J, Cao K, Aftergut K, Cattier J, Fernandez-Vina MA, Menter A (2001) Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies. Hum Mol Genet 10: 1793–1805
Boyce ST, Ham RG (1983) Calcium-regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum-free serial culture. J Invest Dermatol 81: 33–40
Brightbill HD, Libraty DH, Krutzik SR, Yang RB, Belisle JT, Bleharski JR, Maitland M, Norgard MV, Plevy SE, Smale ST, Brennan PJ, Bloom BR, Godowski PJ, Modlin RL (1999) Host defense mechanisms triggered by microbial lipoproteins through Toll-like receptor. Science 285: 732–736
Curry JL, Qin JZ, Bonish B, Carrick R, Bacon P, Panella J, Robinson J, Nickoloff BJ (2003) Innate immune-related receptors in normal and psoriatic skin. Arch Pathol Lab Med 127: 178–186
Donnarumma G, Paoletti I, Buommino E, Orlando M, Tufano MA, Baroni A (2004) Malassezia furfur induces the expression of βdefensin-2 in human keratinocytes in a protein kinase c-dependent manner. Arch Dermatol Res 295: 474–481
Doring HF (1985) Therapy and etiology of sebopsoriasis. Z Hautkr 60: 1940–1942, 1947–1950
Doyle S, Vaidya S, O’ Connel R, Dadgostar H, Dempsey P, Wu T, Rao G, Sun R, Haberland M, Modlin R, Cheng G (2002) IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity 17: 251–263
Dunne A, O’ Neill LA (2003) The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense. Sci STKE 3: 171
Erridge C, Pridmore A, Eley A, Stewart J, Poxton IR (2004) Lipopolysaccharides of Bacteroides fragilis,Clammydia trachomatis and Pseudomonas aeruginosa signal via toll-like receptor 2. J Med Microbiol 53: 735–740
Faergemann J (1992) Pityrosporum infections. In: Elewski BE (ed) Cutaneous fungal infections. Igaku-Shoin, New York, NY, pp 69–83
Harder J, Bartels J, Christophers E, Schrider JM (2001) Isolation and characterization of human β-defensin-3, a novel human inducible peptide antibiotic. J Biol Chem 276: 5707–5713
Harder J, Schroder JM (2005) Psoriatic scales: a promising source for the isolation of human skin-derived antimicrobial proteins. J Leukoc Biol 77: 476–486
Hertz CJ, Wu Q, Porter EM, Zhang YJ, Weismuller KH, Godowski PJ, Granz T, Randell SM, Modlin RL (2003) Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta-defensin-2. J Immunol 171: 6820–6826
Hoshino K, Takeuchi O, Kawai T, Sanjo H, Ogawa T, Takeda Y, Takeda K, Akira S (1999) Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the LPS gene product. J Immunol 162: 3749–3752
Huttner KM, Bevins CL (1999) Antimicrobial peptides as mediators of epithelial host defense. Pediatr Res 45: 785–794
Jia HP, Schutte BC, Schudy A, Linzmeier R, Guthmiller JM, Johnson GK, Tack BF, Mitros JP, Rosenthal A, Ganz T, Mc Cray PB Jr (2001) Discovery of new human beta-defensins using a genomics based approach. Gene 263: 211–218
Kanda N, Tani K, Enomoto U, Nakai K, Watanabe S (2002) The skin fungus-induced Th1- and Th2-related cytokine, chemochine and prostaglandin E2 production in peripheral blood mononuclear cells from patients with atopic dermatitis and psoriasis vulgaris. Clin Exp Allergy 32: 1243–1250
Kopp EB, Medzhitov R (1999) The Toll receptor family and control of innate immunity. Curr Opin Immunol 11: 13–18
Lehner MD, Morath S, Michelsen KS, Schumann RR, Hartung T (2001) Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators. J Immunol 166: 5161–5167
Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA (1996) The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86: 973–983
Licn E, Sellati TJ, Yoshimura A, Flo TH, Rawadi G, Findberg RW, Carrol JD, Espevik T, Ingalls RR, Radolf JD, Golenbock DT (1999) Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. J Biol Chem 274: 33419–33425
Lober CW, Belew PW, Rosenberg EW, Bale G (1982) Patch tests with killed sonicated microflora in patients with psoriasis. Arch Dermatol 118: 322–325
Lui L, Wang L, Jia HP, Zhao C, Heng HH, Shutte BC, Mc Cray PB Jr, Ganz T (1998)Structure and mapping of the human β-defensin HBD-2 gene and its expression at sites of inflammation. Gene 222: 237–244
Marr KA, Balajee SA, Hawnt R, Ozinsky A, Pham U, Akira S, Aderem A, Liles WC (2003) Differential role of Myd88 in macrophage-mediated responses to opportunistic fungal pathogens. Infect Immun 71: 5280–5286
McGettrick AF, O’Neill LAJ (2004) The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction. Mol Immunol 41: 577–582
Muroi M, Ohnishi T, Azumi-Mayuzumi S, Tanamoto T (2003) Lipopolysaccharide-mimetic activities of a Toll-like receptor 2-stimulatory substance(s) in enterobacterial lipopolysaccharide preparations. Infect Immun 71: 3221–3226
Netea MG, Van Der Graaf CA, Vonk AG, Verschueren I, Van Der Meer JW, Kullberg BJ (2002) The role of toll-like receptor TLR-2 and TLR-4 in the host defense against disseminated candidiasis. J Infect Dis 185: 1483–1489
Ozinsky A, Underhill DM, Fontenot JD, Hajjar AM, Smith KD, Wilson CB, Schroeder L, Aderem A (2000) The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors. Proc Natl Acad Sci USA 97: 13766–13771
Perez-Lorenzo R, Zambrano-Zargoza JF, Moo-Castillo K, Luna-Vazquez DL, Ruiz-Guillermo L, Garcia-Latorre E (2003) IgG class antibodies to heat shock-induced streptococcal antigens in psoriatic patients. Int J Dermatol 42: 110–115
Pivarcsi A, Bodai L, Réthi B, Kenderessy-Szabo A, Koreck A, Szell M, Beer Z, Beta-Csorgoo Z, Magocsi M, Rajnavolgyi E, Dobozy A, Kemeny L (2003) Expression and function of Toll-like receptors 2 and 4 in human keratinocytes. Int Immunol 15: 721–730
Rock FL, Hardiman G, Timans JC, Kastelein RA, Bazan JF (1998) A family of human receptors structurally related to Drosophila Toll. Proc Natl Acad Sci USA 95: 588–593
Schibli DJ, Hunter HN, Aeyev V, Starner TD, Wience KJM, Mc Cray PB Jr, Tack BF, Vogel HJ (2002) The solution structures of the human β-defensin lead to a better understanding of the potent bactericidal activity of HBD-3 against Staphilococcus aureus. J Biol Chem 277: 8279–8289
Scott MG, Hancock RE (2000) Cationic antimicrobial peptides and their multifunctional role in the immune system. Crit Rev Immunol 20: 407–431
Svendsen ML, Daneels G, Geysen J, Binderup L, Kragballe K (1997) Proliferation and differentation of cultured human keratinocites is modulated by 1,25(OH)2D3 and synthetic vitamin D3 analogues in a cell density-, calcium- and serum-dependent manner. Pharmacol Toxicol 80: 49–56
Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takeda H, Ogawa T, Takeda K, Akira S (1999) Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components. Immunity 11: 443–451
Underhill DM, Ozinsky A, Hajjar AM, Stevens A, Wilson CB, Bassetti M, Aderem A (1999) The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature 401: 811–815
Underhill DM, Ozinsky A, Smith KD, Aderem A (1999) Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signalling in macrophages. Proc Natl Acad Sci USA 96: 14459–14463
Waldman A, Gilhar A, Duek L, Berdicevski I (2001) Incidence of Candida in psoriasis a study on the fungal flora of psoriatic patients. Mycoses 44: 77–81
Wang JE, Warris A, Ellingsen EA, Jorgensen PF, Flo TH, Espevik T, Solberg R, Verweij PE, Aasen AO(2001) Involvment of CD14 and Toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae. Infect Immun 69: 2402–2406
Weinberg A, Krisanaprakornkit S, Dale BA (1998) Epithelial antimicrobial peptides: review and significance for oral applications. Crit Rev Oral Biol Med 9: 399–414
Yang BR, Mark MR, Gray A, Huang A, Xie MH, Zhang M, Goddard A, Wood WI, Gurney AL, Godowski PJ (1998) Toll-like receptor-2 mediated lipopolysaccharide-induced cellular signaling. Nature 395: 284–288
