Toll-Like Receptor Signaling Pathways

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Saitoh, 2011, Antiviral protein viperin promotes toll-like receptor 7- and toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells, Immunity, 34, 352, 10.1016/j.immuni.2011.03.010

Honda, 2005, IRF-7 is the master regulator of type-I interferon-dependent immune responses, Nature, 434, 772, 10.1038/nature03464

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Negishi, 2006, Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in toll-like receptor-dependent gene induction program, Proc Natl Acad Sci USA, 103, 15136, 10.1073/pnas.0607181103

Takaoka, 2005, Integral role of IRF-5 in the gene induction programme activated by toll-like receptors, Nature, 434, 243, 10.1038/nature03308

Tsujimura, 2004, Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells, J Immunol, 172, 6820, 10.4049/jimmunol.172.11.6820

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Zanoni, 2011, CD14 controls the LPS-induced endocytosis of toll-like receptor 4, Cell, 147, 868, 10.1016/j.cell.2011.09.051

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Stewart, 2010, CD36 ligands promote sterile inflammation through assembly of a toll-like receptor 4 and 6 heterodimer, Nat Immunol, 11, 155, 10.1038/ni.1836

Sheedy, 2013, CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation, Nat Immunol, 14, 812, 10.1038/ni.2639

Palsson-McDermott, 2009, TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway, Nat Immunol, 10, 579, 10.1038/ni.1727

Han, 2010, Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b, Nat Immunol, 11, 734, 10.1038/ni.1908

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Skaug, 2011, Direct, noncatalytic mechanism of IKK inhibition by A20, Mol Cell, 44, 559, 10.1016/j.molcel.2011.09.015

Yuk, 2011, The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by toll-like receptors, Nat Immunol, 12, 742, 10.1038/ni.2064

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