Tolerancia oral en artritis experimental inducida por antígeno en conejos por administración de hidrolizado de cartílago articular

Bax, 2011, Genetics of rheumatoid arthritis: what have we learned?, Immunogenetics, 63, 459, 10.1007/s00251-011-0528-6 Szodoray, 2010, Anti-citrullinated protein/peptide autoantibodies in association with genetic and environmental factors as indicators of disease outcome in rheumatoid arthritis, Autoimmunity Reviews, 9, 140, 10.1016/j.autrev.2009.04.006 Bao, 2012, Nitric oxide-driven hypoxia initiates synovial angiogenesis. Hyperplasia and inflammatory lesions in mice, PLoS One, 7, e34494, 10.1371/journal.pone.0034494 Winyard, 2011, Measurement and meaning of markers of reactive species of oxygen, nitrogen and sulfur in healthy human subjects and patients with inflammatory joint disease, Biochemical Society Transactions, 39, 1226, 10.1042/BST0391226 Imboden, 2009, The immunopathogenesis of rheumatoid arthritis, Annu Rev Pathol., 4, 417, 10.1146/annurev.pathol.4.110807.092254 Szekanecz, 2009, Chemokines and angiogenesis in rheumatoid arthritis. Front Biosci (Elite Ed), 1, 44 Smolen, 2003, Therapeutic strategies for rheumatoid arthritis, Nat Rev Drug Discov, 2, 473, 10.1038/nrd1109 Weiner, 2011, Oral tolerance, Immunol Rev, 241, 241, 10.1111/j.1600-065X.2011.01017.x Smolen, 2007, New therapies for treatment of rheumatoid arthritis, Lancet, 370, 1861, 10.1016/S0140-6736(07)60784-3 Malviya, 2013, BioDrugs, Biological therapies for rheumatoid arthritis: progress to date, 27, 329 Park, 2009, Type II collagen oral tolerance; mechanism and role in collagen-induced arthritis and rheumatoid arthritis, Mod Rheumatol, 19, 581, 10.3109/s10165-009-0210-0 Friedman, 1994, Induction of energy or active suppression following oral tolerance is determined by antigen dosage, Proc Natl Acad Sci, 91, 6688, 10.1073/pnas.91.14.6688 Min, 2006, Antigen induced, tolerogenic CD11c+, CD11b+ dendritic cells are abundant in Peyer's patches during the induction of oral tolerance to type II collagen and suppress experimental collagen-induced arthritis, Arthritis Rheum, 54, 887, 10.1002/art.21647 Min, 2004, Induction of IL-10-producing CD4+ CD25+ T cells in animal model of collagen induced arthritis by oral administration of type II collagen, Arthritis Res Ther, 6, R213, 10.1186/ar1169 Trentham, 1993, Effects of oral administration of type II collagen on rheumatoid arthritis, Science, 261, 1727, 10.1126/science.8378772 Barnett, 1998, Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter placebo-controlled trial, Arthritis Rheum, 41, 290, 10.1002/1529-0131(199802)41:2<290::AID-ART13>3.0.CO;2-R Myers, 2001, Juvenile arthritis and autoimmunity to type II collagen, Arthritis Rheum, 44, 1775, 10.1002/1529-0131(200108)44:8<1775::AID-ART313>3.0.CO;2-V Cazzola, 2000, Oral type II collagen in the treatment of rheumatoid arthritis. A six-month double blind placebo-controlled study, Clin Exp Rheumatol, 18, 571 Faría, 2006, Oral tolerance: Therapeutic implications for autoimmune diseases, Clinical Develop Immunol, 13, 143, 10.1080/17402520600876804 Lipkowski, 2000, Protein hydrolysates for oral tolerance, BioFactors, 12, 147, 10.1002/biof.5520120123 Mortarino, 2008, Tratamiento oral con hidrolizados enzimáticos de colágeno ejerce efectos beneficiosos sobre la evolución de la artritis a nivel experimental y clínico disminuyendo el fenómeno aricular. Correlato con disminución de anticuerpos anti-proteína citrulinada, Medicina (BA), 68, 117 Sanchez-Pernaute, 2003, Fibrin generated in the synovial fluid activates intimal cells from their apical surface: a sequential morphological study in antigen-induced arthritis, Rheumatology, 42, 19, 10.1093/rheumatology/keg021 Green, 1982, Analysis of nitrate, nitrite, and nitrate in biological fluids, Anal Biochem, 126, 131, 10.1016/0003-2697(82)90118-X Kleinbaum DG, Kupper LL, Muller KE, Nizam A. Applied regression analysis and other multivariable methods. 4.th ed; 2008. Kagnoff, 1996, Oral tolerance: Mechanism and possible role in inflammatory joint diseases, Bailliere's Clin Rheumatol, 10, 41, 10.1016/S0950-3579(96)80005-7 Weiner, 1994, Oral tolerance: immunologic mechanism and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens, Annual. Review of Immunology, 12, 809, 10.1146/annurev.iy.12.040194.004113 Meyer, 2000, L’immunomodulation para voie orale dans la polyarthrite, Rev Rhum, 67, 593, 10.1016/S1169-8330(00)00020-X Zhang, 1990, Suppression of adjuvant arthritis in Lewis rats by oral administration of type II collagen, Immunol, 145, 2489 Zhao, 2011, Chicken type II collagen induced immune tolerance of mesenteric lymph node lymphocytes by enhancing beta2-adrenergic receptor desensitization in rats with collagen-induced arthritis, Int Immunopharmacol, 11, 12, 10.1016/j.intimp.2010.09.018 Farooq, 2012, Type II collagen induces peripheral tolerance in BALB/c mice via the generation of CD8+ T regulatory cells, PLoS One, 7, e48635, 10.1371/journal.pone.0048635 Choy, 2001, Control of rheumatoid arthritis by oral tolerance, Arthritis Rheum, 44, 1993, 10.1002/1529-0131(200109)44:9<1993::AID-ART347>3.0.CO;2-A Wei, 2009, A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis, Arthritis Res Ther., 11, R180, 10.1186/ar2870 Báez, 2010, Comparación del tratamiento de artritis reumatoide con medicación convencional (metrotexate y corticoides) y con hidrolizado de colágeno en 20 pacientes. Evaluación clínica y de laboratorio, Medicina (BA), 70, 112