Tissue distribution of humanized anti-human Fas monoclonal antibody (R-125224) based on fas antigen–antibody reaction in collagen-induced arthritis monkeys

Courtenay, 1980, Immunisation against heterologous type II collagen induces arthritis in mice, Nature, 283, 666, 10.1038/283666a0 Haruyama, 2002, Humanization of the mouse anti-Fas antibody HFE7A and crystal structure of the humanized HFE7A Fab Fragment, Biological Pharmaceutical Bulletin, 25, 1537, 10.1248/bpb.25.1537 Ichikawa, 2000, A novel murine anti-human Fas mAb which mitigates lymphadenopathy without hepatotoxicity, International Immunology, 12, 555, 10.1093/intimm/12.4.555 Inazawa, 1999, Fas-induced in vivo apoptosis in bone marrow anti-Fas mAb-induced elimination and successive proliferation of Fas-expressing cells especially those of myeloid lineage, Cell Structure and Function, 24, 151, 10.1247/csf.24.151 Itoh, 1991, The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis, Cell, 66, 233, 10.1016/0092-8674(91)90614-5 Kuwahara, 2001, Therapeutic effect of novel anti-human Fas antibody HFE7A on graft-versus-host disease model, Clinical Immunology, 99, 340, 10.1006/clim.2001.5028 Leithäuser, 1993, Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells, Laboratory Investigation, 69, 415 Mastuno, 2002, Antirheumatic effects of humanized anti-Fas monoclonal antibody in human rheumatoid arthritis/SCID mouse chimera, Journal of Rheumatology, 29, 1609 Matsuno, 1998, Treatment of rheumatoid synovitis with anti-reshaping human interleukin-6 receptor monoclonal antibody: use of rheumatoid arthritis tissue implants in the SCID mouse model, Arthritis Rheumatism, 41, 2014, 10.1002/1529-0131(199811)41:11<2014::AID-ART17>3.0.CO;2-T McKenzie, 1999, The role of the human Fc receptor FcγRIIA in the immune clearance of platelets: a transgenic mouse model, Journal of Immunology, 162, 4311, 10.4049/jimmunol.162.7.4311 Murayama, 2000, Molecular cloning and characterization of cynomolgus monkeys Fas., Human Immunology, 61, 474, 10.1016/S0198-8859(00)00100-2 Nakayama, 2006, A humanized anti-human Fas antibody, R-125224, induces apoptosis in type I activated lymphocytes but not in type II cells, International Immunology, 18, 113, 10.1093/intimm/dxh353 Ogasawara, 1993, Lethal effect of the anti-Fas antibody in mice, Nature, 364, 806, 10.1038/364806a0 Ogawa, 2003, Suppression of osteoclastogenesis in rheumatoid arthritis by induction of apoptosis in activated CD4+T cells, Arthritis Rheumatism, 48, 3350, 10.1002/art.11322 Saito, 2007, In SCID mice with transplanted joint tissues from rheumatism patients, a model mice of human rheumatoid arthritis, anti-human Fas antibody (R-125224) distributes specifically to human synovium, Pharmaceutical Research, 24, 310, 10.1007/s11095-006-9148-5 Sakai, 1998, Potential withdrawal of rheumatoid synovium by the induction of apoptosis using a novel in vivo model of rheumatoid arthritis, Arthritis Rheumatism, 41, 1251, 10.1002/1529-0131(199807)41:7<1251::AID-ART16>3.0.CO;2-B Stuart, 1982, Nature and specificity of the immune response to collagen in type II collagen-induced arthritis in mice, Journal of Clinical Investigation, 69, 673, 10.1172/JCI110495 Takahashi, 1994, Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand, Cell, 76, 969, 10.1016/0092-8674(94)90375-1 Trentham, 1977, Autoimmunity to type II collagen an experimental model of arthritis, Journal of Experimental Medicine, 46, 857, 10.1084/jem.146.3.857 Watanabe-Fukunaga, 1992, Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis, Nature, 356, 314, 10.1038/356314a0 Yu, 1998, Immunohistochemical study of Fas antigen expression in synovial tissues from patients with rheumatoid arthritis, Chinese Medical Journal, 111, 211