Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge

Immunity - Tập 51 Số 5 - Trang 899-914.e7 - 2019
Friedrich Felix Hoyer1, Kamila Naxerova1, Maximilian J. Schloss1, Maarten Hulsmans1, Anil V. Nair1,2, Partha Dutta3, David Calcagno4, Fanny Hérisson1, Atsushi Anzai1, Yuan Sun1, Gregory R. Wojtkiewicz1, David Rohde1, Vanessa Frodermann1, Katrien Vandoorne1, Gabriel Courties1, Yoshiko Iwamoto1, Christopher Garris1, David L. Williams5, Sylvie Breton1,2, Dennis Brown1,2, Michael J. Whalen6, Peter Libby7, Mikaël J. Pittet1, Kevin R. King4,8, Ralph Weissleder1,9, Filip K. Świrski1, Matthias Nahrendorf10,1,11
1Center for Systems Biology, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Simches Research Building, 185 Cambridge Street, Boston, MA 02114, USA
2Program in Membrane Biology and Division of Nephrology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
3Pittsburgh Heart, Lung, Blood, and Vascular Medicine Institute, Division of Cardiology, Department of Medicine, University of Pittsburgh School of Medicine and University of Pittsburgh Medical Center, BST 1720.1, 200 Lothrop Street, Pittsburgh, PA 15213, USA
4Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA
5Department of Surgery and Center of Excellence in Inflammation, Infectious Disease and Immunity, East Tennessee State University, 178 Maple Avenue, Johnson City, TN 37614, USA
6Neuroscience Center and Department of Pediatrics, Massachusetts General Hospital and Harvard Medical School, Boston, 55 Fruit Street, MA 02114, USA
7Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
8Division of Cardiology, Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA
9Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA
10Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, USA
11Department of Internal Medicine I, University Hospital Wuerzburg, Wuerzburg, Germany

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