Time to study time: informing the future of anaphylaxis observation duration

Kraft M, Scherer Hofmeier K, Rueff F, et al. Risk factors and characteristics of biphasic anaphylaxis. J Allergy Clin Immunol Pract. 2020;8(10):3388-95 e6. Dribin TE, Sampson HA, Camargo CA Jr, et al. Persistent, refractory, and biphasic anaphylaxis: a multidisciplinary Delphi study. J Allergy Clin Immunol. 2020;146(5):1089–96. Burroughs-Ray DC, Wells DR, Dennis MM, et al. Clinical guideline highlights for the hospitalist: anaphylaxis management in adults and children. J Hosp Med. 2021;16(2):98–9. Simard. Factors influencing emergency department observation time following anaphylaxis: a systematic review. Can J Emerg Med. 2021. Casale TB, Wang J, Nowak-Wegrzyn A. Acute at home management of anaphylaxis during the Covid-19 pandemic. J Allergy Clin Immunol Pract. 2020;8(6):1795–7. Alqurashi W, Ellis AK. Do corticosteroids prevent biphasic anaphylaxis? J Allergy Clin Immunol Pract. 2017;5(5):1194–205. Sheikh A, ten Broek V, Brown SG, et al. H1-antihistamines for the treatment of anaphylaxis with and without shock. Cochrane Database Syst Rev. 2007;1:CD006160. Osmond MH, Klassen TP, Wells GA, et al. CATCH: a clinical decision rule for the use of computed tomography in children with minor head injury. CMAJ. 2010;182(4):341–8. Stiell IG, Wells GA, Vandemheen K, et al. The Canadian CT Head Rule for patients with minor head injury. Lancet. 2001;357(9266):1391–6. Shaker MS, Wallace DV, Golden DBK, et al. Anaphylaxis-a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis. J Allergy Clin Immunol. 2020;145(4):1082–123.