Time-resolved FTIR study of light-driven sodium pump rhodopsins

Physical Chemistry Chemical Physics - Tập 20 Số 26 - Trang 17694-17704
Hui‐Fen Chen1,2,3,4,5, Keiichi Inoue1,6,7,8,9, Hikaru Ono1,10,6,11, Rei Abe‐Yoshizumi1,10,6,11, Akimori Wada10,12,13,14, Hideki Kandori1,10,6,7,8
1Department of Life Science and Applied Chemistry, Nagoya Institute of Technology, Showa-ku, Nagoya, 466-8555, Japan
2Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, 100, Shih-Chuan 1st Road, Kaohsiung, Taiwan
3Kaohsiung
4 Kaohsiung Medical University
5Taiwan
6Nagoya 466-8555
7OptoBioTechnology Research Center
8OptoBioTechnology Research Center, Nagoya Institute of Technology, Showa-ku, Nagoya 466-8555, Japan
9PRESTO, Japan Science and Technology Agency, 4-1-8 Honcho Kawaguchi, Saitama 332-0012, Japan
10Japan
11 Nagoya Institute of Technology
12Kobe 658-8558
13Kobe Pharmaceutical University
14Laboratory of Organic Chemistry for Life Science, Kobe Pharmaceutical University, Kobe 658-8558, Japan

Tóm tắt

Light-driven sodium ion pump rhodopsin (NaR) is a new functional class of microbial rhodopsin. Present step-scan time-resolved FTIR spectroscopy revealed that the K, L and O intermediates of NaRs contain 13-cis retinal with similar distortion.

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