Time-of-day-dependent variation of the human liver transcriptome and metabolome is disrupted in MASLD

JHEP Reports - Tập 6 - Trang 100948 - 2024
Manuel Johanns1, Joel T. Haas1, Violetta Raverdy2, Jimmy Vandel1, Julie Chevalier-Dubois1, Loic Guille1, Bruno Derudas1, Benjamin Legendre2, Robert Caiazzo2, Helene Verkindt2, Viviane Gnemmi3, Emmanuelle Leteurtre3, Mehdi Derhourhi4, Amélie Bonnefond4,5, Philippe Froguel4,5, Jérôme Eeckhoute1, Guillaume Lassailly6, Philippe Mathurin6, François Pattou2, Bart Staels1
1Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR1011-EGID, F-59000 Lille, France
2Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR1190-EGID, F-59000 Lille, France
3Univ. Lille, Inserm, CHU Lille, UMR 1172, Lille, France
4Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, UMR 1283/8199-EGID, F-59000 Lille, France
5Department of Metabolism, Imperial College London; London, United Kingdom
6Univ. Lille, Inserm, CHU Lille, UMR 995-LIRIC, Lille, France

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