Time- and dose-dependent volume decreases in subcortical grey matter structures of glioma patients after radio(chemo)therapy

Cayuela, 2019, Cognitive and brain structural changes in long-term oligodendroglial tumor survivors, Neuro-Oncology, 21, 1470, 10.1093/neuonc/noz130 Douw, 2009, Cognitive and radiological effects of radiotherapy in patients with low-grade glioma: long-term follow-up, The Lancet Neurology, 8, 810, 10.1016/S1474-4422(09)70204-2 Surma-aho, 2001, Adverse long-term effects of brain radiotherapy in adult low-grade glioma patients, Neurology, 56, 1285, 10.1212/WNL.56.10.1285 Witzmann, 2021, MR image changes of normal-appearing brain tissue after radiotherapy, Cancers, 13, 1573, 10.3390/cancers13071573 Raschke, 2020, Dose dependent cerebellar atrophy in glioma patients after radio(chemo)therapy, Radiother Oncol, 150, 262, 10.1016/j.radonc.2020.07.044 Petr, 2018, Photon vs. proton radiochemotherapy: Effects on brain tissue volume and perfusion, Radiother Oncol, 128, 121, 10.1016/j.radonc.2017.11.033 Tobin, 2019, Human hippocampal neurogenesis persists in aged adults and Alzheimer’s disease patients, Cell Stem Cell, 24, 974, 10.1016/j.stem.2019.05.003 Ma, 2017, A prospective evaluation of hippocampal radiation dose volume effects and memory deficits following cranial irradiation, Radiother Oncol, 125, 234, 10.1016/j.radonc.2017.09.035 Gondi, 2012, Hippocampal dosimetry predicts neurocognitive function impairment after fractionated stereotactic radiotherapy for benign or low-grade adult brain tumors, Internat J Radiat Oncol Biol Phys, 83, e487, 10.1016/j.ijrobp.2011.10.021 Hernández-Rabaza, 2009, Inhibition of adult hippocampal neurogenesis disrupts contextual learning but spares spatial working memory, long-term conditional rule retention and spatial reversal, Neuroscience, 159, 59, 10.1016/j.neuroscience.2008.11.054 Belderbos, 2021, Phase 3 randomized trial of prophylactic cranial irradiation with or without hippocampus avoidance in SCLC (NCT01780675), J Thoracic Oncol, 16, 840, 10.1016/j.jtho.2020.12.024 Brown, 2020, Hippocampal avoidance during whole-brain radiotherapy plus memantine for patients with brain metastases: Phase III trial NRG oncology CC001, JCO, 38, 1019, 10.1200/JCO.19.02767 Lv, 2019, Radiation-induced hippocampal atrophy in patients with nasopharyngeal carcinoma early after radiotherapy: a longitudinal MR-based hippocampal subfield analysis, Brain Imaging Behav, 13, 1160, 10.1007/s11682-018-9931-z Catani, 2013, A revised limbic system model for memory, emotion and behaviour, Neurosci Biobehav Rev, 37, 1724, 10.1016/j.neubiorev.2013.07.001 Herrero, 2002, Functional anatomy of thalamus and basal ganglia, Child's Nervous System, 18, 386, 10.1007/s00381-002-0604-1 Takeshita, 2020, Early volume reduction of the hippocampus after whole-brain radiation therapy: an automated brain structure segmentation study, Jpn J Radiol, 38, 118, 10.1007/s11604-019-00895-3 Nagtegaal, 2021, Dose-dependent volume loss in subcortical deep grey matter structures after cranial radiotherapy, Clin Transl Radiat Oncol, 26, 35, 10.1016/j.ctro.2020.11.005 Eekers, 2018, The EPTN consensus-based atlas for CT- and MR-based contouring in neuro-oncology, Radiother Oncol, 128, 37, 10.1016/j.radonc.2017.12.013 Seidlitz, 2021, Final results of the prospective biomarker trial PETra: [11C]-MET-accumulation in postoperative PET/MRI predicts outcome after radiochemotherapy in glioblastoma, Clin Cancer Res, 27, 1351, 10.1158/1078-0432.CCR-20-1775 Mayo, 2010, Radiation associated brainstem injury, Int J Radiat Oncol Biol Phys, 76, S36, 10.1016/j.ijrobp.2009.08.078 Mayo, 2010, Radiation dose-volume effects of optic nerves and chiasm, Int J Radiat Oncol Biol Phys, 76, S28, 10.1016/j.ijrobp.2009.07.1753 Lawrence, 2010, Radiation dose-volume effects in the brain, Int J Radiat Oncol Biol Phys, 76, S20, 10.1016/j.ijrobp.2009.02.091 Lambrecht, 2018, Radiation dose constraints for organs at risk in neuro-oncology; the European Particle Therapy Network consensus, Radiother Oncol, 128, 26, 10.1016/j.radonc.2018.05.001 Grabner, 2006, Symmetric atlasing and model based segmentation: an application to the hippocampus in older adults, 58 Jenkinson, 2012, FSL, NeuroImage, 62, 782, 10.1016/j.neuroimage.2011.09.015 Avants, 2011, A reproducible evaluation of ANTs similarity metric performance in brain image registration, NeuroImage, 54, 2033, 10.1016/j.neuroimage.2010.09.025 Tustison, 2013, Explicit B-spline regularization in diffeomorphic image registration, Front Neuroinform, 7, 10.3389/fninf.2013.00039 Gommlich, 2022, Overestimation of grey matter atrophy in glioblastoma patients following radio(chemo)therapy, Magn Reson Mater Phy, 35, 145, 10.1007/s10334-021-00922-3 R.C. Team. R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing. Vienna, Austria; 2019; Available from: https://www.R-project.org/. Huynh-Le, 2019, Dose-dependent atrophy of the amygdala after radiotherapy, Radiother Oncol, 136, 44, 10.1016/j.radonc.2019.03.024 Seibert, 2017, Radiation dose-dependent hippocampal atrophy detected with longitudinal volumetric magnetic resonance imaging, Internat J Radiat Oncol Biol Phys, 97, 263, 10.1016/j.ijrobp.2016.10.035 Prust, 2015, Standard chemoradiation for glioblastoma results in progressive brain volume loss, Neurology, 85, 683, 10.1212/WNL.0000000000001861 Dutz, 2019, Development and validation of NTCP models for acute side-effects resulting from proton beam therapy of brain tumours, Radiother Oncol, 130, 164, 10.1016/j.radonc.2018.06.036 Donix, 2013, APOE associated hemispheric asymmetry of entorhinal cortical thickness in aging and Alzheimer’s disease, Psych Res Neuroimag, 214, 212, 10.1016/j.pscychresns.2013.09.006