Time Course of the Apoptotic Cascade and Effects of Caspase Inhibitors in Adult Rat Ventricular Cardiomyocytes

Journal of Molecular and Cellular Cardiology - Tập 33 Số 5 - Trang 983-994 - 2001
Keisuke Suzuki1, Sawa Kostin1, Veronika Person1, Albrecht Elsässer2, Jutta Schaper1
1Max-Planck-Institute, Bad Nauheim, Germany, University Freiburg, Freiburg, Germany
2Bad Nauheim, Germany, Department of Cardiology, University Freiburg, Freiburg, Germany

Tóm tắt

Từ khóa


Tài liệu tham khảo

Olivetti, 1996, Acute myocardial infarction in humans is associated with activation of programmed myocyte cell death in the surviving portion of the heart, J Mol Cell Cardiol, 28, 2005, 10.1006/jmcc.1996.0193

Narula, 1996, Apoptosis in myocytes in end stage heart failure, N Engl J Med, 335, 1182, 10.1056/NEJM199610173351603

Mallat, 1996, Evidence of apoptosis in arrhythmogenic right ventricular dysplasia, N Engl J Med, 335, 1190, 10.1056/NEJM199610173351604

Elsässer, 2000, A self-perpetuating vicious cycle of tissue damage in hibernating myocardium, Mol Cell Biochem, 213, 17, 10.1023/A:1007182617215

Olivetti, 1997, Apoptosis in the failing human heart, N Engl J Med, 336, 1131, 10.1056/NEJM199704173361603

Schaper, 1999, The role of cell death in heart failure, Circ Res, 85, 867, 10.1161/01.RES.85.9.867

Kang, 2000, Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation, Circ Res, 87, 118, 10.1161/01.RES.87.2.118

Cook, 1999, Regulation of Bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes. Association with changes in mitochondrial membrane potential, Circ Res, 85, 940, 10.1161/01.RES.85.10.940

Turner, 1998, Oxidative stress induces DNA fragmentation and caspase activation via the c-Jun NH2-terminal kinase pathway in H9c2 cardiac muscle cells, J Mol Cell Cardiol, 30(9), 1789, 10.1006/jmcc.1998.0743

von Harsdorf, 1999, Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis, Circulation, 99, 2934, 10.1161/01.CIR.99.22.2934

Schaub, 1997, Various hypertrophic stimuli induce distinct phenotypes in cardiomyocytes, J Mol Med, 75, 901, 10.1007/s001090050182

Bugaisky, 1989, Differentiation of adult rat cardiomyocytes in cell culture, Circ Res, 64, 493, 10.1161/01.RES.64.3.493

Maeno, 1997, Multifactorial origin of the reduction of myofilaments causing contractile dysfunction in failing hearts (abstract), In Circulation, 96 (Suppl. I), 3865

Maeno, 1997, Role of the cytoskeleton in sarcomerogenesis in adult cardiomyocytes in culture (abstract), In J Mol Cell Cardiol, 29(5), Th15

Kostin, 1999, SpatioÍtemporal development and distribution of interÍcellular junctions in adult rat cardiomyocytes in culture, Circ Res, 85, 154, 10.1161/01.RES.85.2.154

Heling, 2000, Increased expression of cytoskeletal, linkage, and extracellular proteins in failing human myocardium, Circ Res, 86, 846, 10.1161/01.RES.86.8.846

Haunstetter, 1998, Apoptosis. Basic mechanisms and implications for cardiovascular disease, Circ Res, 82, 1111, 10.1161/01.RES.82.11.1111

Holly, 1999, Caspase inhibition reduces myocyte cell death induced by myocardial ischemia and reperfusion in vivo, J Mol Cell Cardiol, 31, 1709, 10.1006/jmcc.1999.1006

Okamura, 2000, Effect of caspase inhibitors on myocardial infarct size and myocyte DNA fragmentation in the ischemia-reperfused rat heart, Cardiovasc Res, 45, 642, 10.1016/S0008-6363(99)00271-0

Yaoita, 1998, Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor, Circulation, 97(3), 276, 10.1161/01.CIR.97.3.276

Person, 2000, Antisense oligonucleotide experiments elucidate the essential role of titin in sarcomerogenesis in adult rat cardiomyocytes in long-term culture, J Cell Sci, 113, 3851, 10.1242/jcs.113.21.3851

Speir, 1992, Acidic and basic fibroblast growth factors in adult rat heart myocytes. Localization, regulation in culture, and effects on DNA synthesis, Circ Res, 71, 251, 10.1161/01.RES.71.2.251

Hampton, 1997, Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis, FEBS Lett, 414(3), 552, 10.1016/S0014-5793(97)01068-5

Moissac, 2000, Caspase activation and mitochondrial cytochrome c release during hypoxia-mediated apoptosis of adult ventricular myocytes, J Mol Cell Cardiol, 32, 53, 10.1006/jmcc.1999.1057

Susin, 1998, Mitochondria as regulators of apoptosis: doubt no more, Biochem Biophys Acta, 1366, 151

Finucane, 1999, Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL, J Biol Chem, 274(4), 2225, 10.1074/jbc.274.4.2225

Krohn, 1998, Staurosporine-induced apoptosis of cultured rat hippocampal neurons involves caspase-1-like proteases as upstream initiators and increased production of superoxide as a main downstream effector, J Neurosci, 18(20), 8186, 10.1523/JNEUROSCI.18-20-08186.1998

Green, 1998, Mitochondria and apoptosis, Science, 281, 1309, 10.1126/science.281.5381.1309

Kroemer, 1998, The mitochondrial death/life regulator in apoptosis and necrosis, Ann Rev Physiol, 60, 619, 10.1146/annurev.physiol.60.1.619

Vercammen, 1998, Dual signaling of the Fas receptor: initiation of both apoÍptotic and necrotic cell death pathways, J Exp Med, 188(5), 919, 10.1084/jem.188.5.919

Shimizu, 1996, Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors, Oncogene, 13, 21

Shimizu, 1998, Induction of hydrogen peroxide production and Bax expression by caspase-3(-like) proteases in tyrosine kinase inhibitor-induced apoptosis in human small cell lung carcinoma cells, Exp Cell Res, 238(1), 197, 10.1006/excr.1997.3823

Pawlowski, 2000, Bax-induced apoptotic cell death, Proc Natl Acad Sci USA, 97, 529, 10.1073/pnas.97.2.529

Gavrieli, 1992, Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation, J Cell Biol, 119, 4493, 10.1083/jcb.119.3.493

Frankfurt, 1996, Monoclonal antibody to single-stranded DNA is a specific and sensitive cellular marker of apoptosis, Exp Cell Res, 226, 387, 10.1006/excr.1996.0240

Kanoh, 1999, Significance of myocytes with positive DNA in situ nick end-labeling (TUNEL) in hearts with dilated cardiomyopathy. Not apoptosis but DNA repair, Circulation, 99, 2757, 10.1161/01.CIR.99.21.2757

Kockx, 1998, RNA synthesis and splicing interferes with DNA in situ end labeling techniques used to detect apoptosis, Am J Pathol, 152, 885