Thymic Selection Determines γδ T Cell Effector Fate: Antigen-Naive Cells Make Interleukin-17 and Antigen-Experienced Cells Make Interferon γ

Immunity - Tập 29 - Trang 90-100 - 2008
Kirk D.C. Jensen1, Xiaoqin Su1, Sunny Shin1, Luke Li1, Sawsan Youssef2,3, Sho Yamasaki4, Lawrence Steinman2,3, Takashi Saito4, Richard M. Locksley5, Mark M. Davis1,2,6, Nicole Baumgarth7, Yueh-hsiu Chien1,2
1Department of Microbiology and Immunology, Stanford University, Stanford, CA 94305, USA
2Program of Immunology, Stanford University, Stanford, CA 94305, USA
3Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA
4Laboratory for Cell Signaling, RIKEN Research Center for Allergy and Immunology, Yokohama, Kanagawa 230-0045, Japan
5Howard Hughes Medical Institute, Department of Medicine and Microbiology/Immunology, University of California San Francisco, San Francisco, CA 94143, USA
6Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305 USA
7Center for Comparative Medicine, University of California, Davis, Davis, CA 95616, USA

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