Thromboxane-dependent coronary vasoconstriction in obese mice: Role of peroxynitrite

Obesity and overweight, (n.d.). 〈https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight〉 (Accessed 13 July 2021). Haslam, 2005, Obesity, Lancet, 366, 1197, 10.1016/S0140-6736(05)67483-1 Barton, 2012, Obesity and risk of vascular disease: importance of endothelium-dependent vasoconstriction, Br. J. Pharmacol., 165, 591, 10.1111/j.1476-5381.2011.01472.x Roberts, 2000, Enhanced NO inactivation and hypertension induced by a high-fat, refined-carbohydrate diet, Hypertension, 36, 423, 10.1161/01.HYP.36.3.423 Gamez-Mendez, 2015, Oxidative stress-dependent coronary endothelial dysfunction in obese mice, PLoS One, 10, 10.1371/journal.pone.0138609 Katusic, 1993, Endothelium-dependent contractions to oxygen-derived free radicals in the canine basilar artery, Am. J. Physiol. - Hear. Circ. Physiol., 264 Muñoz, 2015, COX-2 is involved in vascular oxidative stress and endothelial dysfunction of renal interlobar arteries from obese Zucker rats, Free Radic. Biol. Med., 84, 77, 10.1016/j.freeradbiomed.2015.03.024 Tian, 2012, Oxidative stress-dependent cyclooxygenase-2-derived prostaglandin F 2α impairs endothelial function in renovascular hypertensive rats, Antioxidants Redox Signal., 16, 363, 10.1089/ars.2010.3874 Wilson, 2009, Activation-dependent stabilization of the human thromboxane receptor: role of reactive oxygen species, J. Lipid Res., 50, 1047, 10.1194/jlr.M800447-JLR200 Matrougui, 1997, Impaired nitric oxide- and prostaglandin-mediated responses to flow in resistance arteries of hypertensive rats, Hypertension, 30, 942, 10.1161/01.HYP.30.4.942 Landino, 1996, Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis, Proc. Natl. Acad. Sci. USA, 93, 15069, 10.1073/pnas.93.26.15069 Stefanutti, 2007, Peroxynitrite decomposition catalyst FeTMPyP provides partial protection against intestinal ischemia and reperfusion injury in infant rats, Pediatr. Res., 62, 43, 10.1203/PDR.0b013e31806790c0 Dunn, 2021, Thioredoxin deficiency exacerbates vascular dysfunction during diet-induced obesity in small mesenteric artery in mice, Microcirculation, 28, 10.1111/micc.12674 Bell, 2011, Retrograde heart perfusion: The Langendorff technique of isolated heart perfusion, J. Mol. Cell. Cardiol., 50, 940, 10.1016/j.yjmcc.2011.02.018 Kameritsch, 2021, The mitochondrial thioredoxin reductase system (TrxR2) in vascular endothelium controls peroxynitrite levels and tissue integrity, Proc. Natl. Acad. Sci. USA, 118, 10.1073/pnas.1921828118 Ketonen, 2010, Caloric restriction reverses high-fat diet-induced endothelial dysfunction and vascular superoxide production in C57Bl/6 mice, Heart Vessels, 25, 254, 10.1007/s00380-009-1182-x Tran, 2020, The vascular consequences of metabolic syndrome: rodent models, endothelial dysfunction, and current therapies, Front. Pharmacol., 11, 10.3389/fphar.2020.00148 Al Suwaidi, 2001, Association between obesity and coronary atherosclerosis and vascular remodeling, Am. J. Cardiol., 88, 1300, 10.1016/S0002-9149(01)02093-8 Frisbee, 2018, Type 2 diabetes mellitus in the Goto-Kakizaki rat impairs microvascular function and contributes to premature skeletal muscle fatigue, J. Appl. Physiol., 126, 626, 10.1152/japplphysiol.00751.2018 Baretella, 2017, Endothelial overexpression of endothelin-1 modulates aortic, carotid, iliac and renal arterial responses in obese mice, Acta Pharmacol. Sin., 38, 498, 10.1038/aps.2016.138 Na, 2019, Integrative omics reveals metabolic and transcriptomic alteration of nonalcoholic fatty liver disease in catalase knockout mice, Biomol. Ther., 27, 134, 10.4062/biomolther.2018.175 Wang, 2018, Genistein ameliorates non-alcoholic fatty liver disease by targeting the thromboxane A2 pathway, J. Agric. Food Chem., 66, 5853, 10.1021/acs.jafc.8b01691 Quilley, 1989, Role of endoperoxides in arachidonic acid‐induced vasoconstriction in the isolated perfused kidney of the rat, Br. J. Pharmacol., 96, 111, 10.1111/j.1476-5381.1989.tb11790.x Retailleau, 2010, Reactive oxygen species and cyclooxygenase 2-derived thromboxane A2 reduce angiotensin II type 2 receptor vasorelaxation in diabetic rat resistance arteries, Hypertension, 55, 339, 10.1161/HYPERTENSIONAHA.109.140236 Kuang, 2017, The enhancement of TXA2 receptors-mediated contractile response in intrarenal artery dysfunction in type 2 diabetic mice, Eur. J. Pharmacol., 805, 93, 10.1016/j.ejphar.2017.03.006 Smyth, 2010, Thromboxane and the thromboxane receptor in cardiovascular disease, Clin. Lipidol., 5, 10.2217/clp.10.11 Gupte, 1996, Superoxide and nitroglycerin stimulate release of PGF2α and TxA2 in isolated rat heart, Am. J. Physiol., 271 Cosentino, 2003, High glucose causes upregulation of cyclooxygenase-2 and alters prostanoid profile in human endothelial cells: role of protein kinase C and reactive oxygen species, Circulation, 107, 1017, 10.1161/01.CIR.0000051367.92927.07 García-Redondo, 2015, C-Src, ERK1/2 and Rho kinase mediate hydrogen peroxide-induced vascular contraction in hypertension: role ofTXA2, NAD(P)H oxidase and mitochondria, J. Hypertens., 33, 77, 10.1097/HJH.0000000000000383 Zou, 2002, Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite, J. Clin. Investig., 109, 10.1172/JCI0214442 Ferrer-Sueta, 2018, Biochemistry of peroxynitrite and protein tyrosine nitration, Chem. Rev., 118, 1338, 10.1021/acs.chemrev.7b00568 Cruz, 2016, Relevance of peroxynitrite formation and 3- nitrotyrosine on spermatozoa physiology, Porto Biomed. J., 1, 129, 10.1016/j.pbj.2016.07.004 Li, 2019, Structure effect of water-soluble iron porphyrins on catalyzing protein tyrosine nitration in the presence of nitrite and hydrogen peroxide, Nitric Oxide Biol. Chem., 91, 42, 10.1016/j.niox.2019.07.007 Wu, 2021, Structure relationship of metalloporphyrins in inhibiting the aggregation of hIAPP, Int. J. Biol. Macromol., 167, 141, 10.1016/j.ijbiomac.2020.11.161 Santilli, 2015, Oxidative stress-related mechanisms affecting response to aspirin in diabetes mellitus, Free Radic. Biol. Med., 80, 101, 10.1016/j.freeradbiomed.2014.12.010 Majed, 2012, Molecular mechanisms regulating the vascular prostacyclin pathways and their adaptation during pregnancy and in the newborn, Pharmacol. Rev., 64, 540, 10.1124/pr.111.004770