Thrombopoietin gene expression in the developing human central nervous system

Ballmaier, 2001, c-mpl mutations are the cause of congenital amegakaryocytic thrombocytopenia, Blood, 97, 139, 10.1182/blood.V97.1.139 Bartley, 1994, Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl, Cell, 77, 1117, 10.1016/0092-8674(94)90450-2 Brines, 2000, Erythropoietin crosses the blood–brain barrier to protect against experimental brain injury, Proc. Natl. Acad. Sci. USA, 97, 10526, 10.1073/pnas.97.19.10526 Cardier, 1998, Thrombopoietin and its receptor, c-mpl, are constitutively expressed by mouse liver endothelial cells: evidence of thrombopoietin as a growth factor for liver endothelial cells, Blood, 91, 923, 10.1182/blood.V91.3.923 Celik, 2002, Erythropoietin prevents motor neuron apoptosis and neurologic disability in experimental spinal cord ischemic injury, Proc. Natl. Acad. Sci. USA, 99, 2258, 10.1073/pnas.042693799 Chang, 1996, Differential mechanisms in the regulation of endogenous levels of thrombopoietin and interleukin-11 during thrombocytopenia: insight into the regulation of platelet production, Blood, 88, 3354, 10.1182/blood.V88.9.3354.bloodjournal8893354 Chang, 1995, Cloning and characterization of the human megakaryocyte growth and development factor (MGDF) gene, J. Biol. Chem., 270, 511, 10.1074/jbc.270.2.511 Columbyova, 1995, Thrombopoietin receptor expression in human cancer cell lines and primary tissues, Cancer Res., 55, 3509 Dame, 2001, Thrombopoietin in thrombocytopenias of childhood, Semin. Thromb. Hemost., 27, 215, 10.1055/s-2001-15251 Dame, 2000, Erythropoietin gene expression in different areas of the developing human central nervous system, Dev. Brain Res., 125, 69, 10.1016/S0165-3806(00)00118-8 Dame, 1998, Erythropoietin mRNA expression in human fetal and neonatal tissue, Blood, 92, 3218, 10.1182/blood.V92.9.3218 Dame, 2001, The biology of erythropoietin in the central nervous system and its neurotrophic and neuroprotective potential, Biol. Neonate, 79, 228, 10.1159/000047097 de Sauvage, 1994, Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand, Nature, 369, 533, 10.1038/369533a0 Foster, 1997, The biological significance of truncated and full-length forms of mpl ligand, 203 Gurney, 1995, Genomic structure, chromosomal localization, and conserved alternative splice forms of thrombopoietin, Blood, 85, 981, 10.1182/blood.V85.4.981.bloodjournal854981 Ihara, 1999, Identification of mutations in the c-mpl gene in congenital amegakaryocytic thrombocytopenia, Proc. Natl. Acad. Sci. USA, 96, 3132, 10.1073/pnas.96.6.3132 Juul, 1998, Erythropoietin and erythropoietin receptor in the developing human central nervous system, Pediatr. Res., 43, 40, 10.1203/00006450-199801000-00007 Kaushansky, 1995, Thrombopoietin: the primary regulator of platelet production, Blood, 86, 419, 10.1182/blood.V86.2.419.bloodjournal862419 Kaushansky, 2001, CAMT: new findings and new questions, Blood, 97, 1, 10.1182/blood.V97.1.1 Kimura, 1998, Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin, Proc. Natl. Acad. Sci. USA, 95, 1195, 10.1073/pnas.95.3.1195 Konishi, 1993, Trophic effect of erythropoietin and other hematopoietic factors on central cholinergic neurons in vitro and in vivo, Brain Res., 609, 29, 10.1016/0006-8993(93)90850-M Kuter, 1995, The reciprocal relationship of thrombopoietin (c-Mpl ligand) to changes in the platelet mass during busulfan-induced thrombocytopenia in the rabbit, Blood, 85, 2720, 10.1182/blood.V85.10.2720.bloodjournal85102720 Li, 1995, Thrombopoietin and neurotrophins share a common domain, Blood, 86, 1643, 10.1182/blood.V86.4.1643.bloodjournal8641643 Li, 1996, Thrombopoietin and its alternatively spliced form are expressed in human amygdala and hippocampus, Blood, 87, 5382, 10.1182/blood.V87.12.5382.bloodjournal87125382 Lok, 1994, Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo, Nature, 369, 565, 10.1038/369565a0 Marti, 1996, Erythropoietin gene expression in human, monkey and murine brain, Eur. J. Neurosci., 8, 666, 10.1111/j.1460-9568.1996.tb01252.x Muto, 2000, Functional analysis of the C-terminal region of recombinant human thrombopoietin. C-terminal region of thrombopoietin is a ‘shuttle’ peptide to help secretion, J. Biol. Chem., 275, 12090, 10.1074/jbc.275.16.12090 Nagata, 1997, Serum thrombopoietin level is not regulated by transcription but by the total counts of both megakaryocytes and platelets during thrombocytopenia and thrombocytosis, Thromb. Haemost., 77, 808, 10.1055/s-0038-1656057 Nakanishi, 1999, Thrombopoietin expression in normal and hypobaric hypoxia-induced thrombocytopenic rats, Lab. Invest., 79, 679 Nomura, 1997, Cellular localization of thrombopoietin mRNA in the liver by in situ hybridization, Exp. Hematol., 25, 565 Sakanaka, 1998, In vivo evidence that erythropoietin protects neurons from ischemic damage, Proc. Natl. Acad. Sci. USA, 95, 4635, 10.1073/pnas.95.8.4635 Sasaki, 1999, Production of thrombopoietin by human carcinomas and its novel isoforms, Blood, 94, 1952, 10.1182/blood.V94.6.1952 Sola, 1999, Thrombopoietin (Tpo) in the fetus and neonate: Tpo concentrations in preterm and term neonates, and organ distribution of Tpo and its receptor (c-mpl) during human fetal development, Early Hum. Dev., 53, 239, 10.1016/S0378-3782(98)00077-2 Sungaran, 2000, The role of platelet alpha-granular proteins in the regulation of thrombopoietin messenger RNA expression in human bone marrow stromal cells, Blood, 95, 3094, 10.1182/blood.V95.10.3094 Sungaran, 1997, Localization and regulation of thrombopoietin mRNA expression in human kidney, liver, bone marrow, and spleen using in situ hybridization, Blood, 89, 101, 10.1182/blood.V89.1.101 Wolber, 1999, Expression of the thrombopoietin gene in human fetal and neonatal tissues, Blood, 94, 97, 10.1182/blood.V94.1.97.413k20_97_105 Wolber, 2001, Hepatic thrombopoietin mRNA is increased in acute inflammation, Thromb. Haemost., 86, 1421, 10.1055/s-0037-1616745 Wolber, 1999, Hepatic thrombopoietin mRNA levels in acute and chronic liver failure of childhood, Hepatology, 29, 1739, 10.1002/hep.510290627 Wolber, 2000, Interleukin-6 increases thrombopoietin production in human hepatoma cells HepG2 and Hep3B, J. Interferon Cytokine Res., 20, 499, 10.1089/10799900050023915 Yamashita, 2000, Hepatocyte growth factor/scatter factor enhances the thrombopoietin mRNA expression in rat hepatocytes and cirrhotic rat livers, J. Gastroenterol. Hepatol., 15, 83, 10.1046/j.1440-1746.2000.02040.x Zhang, 1998, Modulation of microglia by stem cell factor, J. Neurosci. Res., 53, 29, 10.1002/(SICI)1097-4547(19980701)53:1<29::AID-JNR4>3.0.CO;2-L