Thrombolyse intraveineuse dans l’ischémie cérébrale de phase aiguë : sur quoi reposent les recommandations ?

Berge, 2021, European Stroke Organisation (ESO) guidelines on intravenous thrombolysis for acute ischaemic stroke, Eur Stroke J, 6, 10.1177/2396987321989865 Wardlaw, 2014, Thrombolysis for acute ischaemic stroke, Cochrane Database Syst Rev, CD000213 Emberson, 2014, Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials, Lancet, 384, 1929, 10.1016/S0140-6736(14)60584-5 IST-3 collaborative group, 2012, The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial, Lancet, 379, 2352, 10.1016/S0140-6736(12)60768-5 Turc, 2019, European Stroke Organisation (ESO) - European Society for Minimally Invasive Neurological Therapy (ESMINT) Guidelines on Mechanical Thrombectomy in Acute Ischaemic Stroke Endorsed by Stroke Alliance for Europe (SAFE), Eur Stroke J, 4, 6, 10.1177/2396987319832140 Ma, 2019, Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke, N Engl J Med, 380, 1795, 10.1056/NEJMoa1813046 Ringleb, 2019, Extending the time window for intravenous thrombolysis in acute ischemic stroke using magnetic resonance imaging-based patient selection, Int J Stroke, 14, 483, 10.1177/1747493019840938 Rimmele, 2014, Wake-up stroke: clinical characteristics, imaging findings, and treatment option — an update, Front Neurol, 5, 35, 10.3389/fneur.2014.00035 Thomalla, 2018, MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset, N Engl J Med, 379, 611, 10.1056/NEJMoa1804355 Koga, 2014, THrombolysis for Acute Wake-up and unclear-onset Strokes with alteplase at 0.6 mg/kg (THAWS) Trial, Int J Stroke, 9, 1117, 10.1111/ijs.12360 Thomalla, 2020, Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data, Lancet, 396, 1574, 10.1016/S0140-6736(20)32163-2 Haley, 2010, Phase IIB/III trial of tenecteplase in acute ischemic stroke: results of a prematurely terminated randomized clinical trial, Stroke, 41, 707, 10.1161/STROKEAHA.109.572040 Huang, 2015, Alteplase versus tenecteplase for thrombolysis after ischaemic stroke (ATTEST): a phase 2, randomised, open-label, blinded endpoint study, Lancet Neurol, 14, 368, 10.1016/S1474-4422(15)70017-7 Logallo, 2017, Tenecteplase versus alteplase for management of acute ischaemic stroke (NOR-TEST): a phase 3, randomised, open-label, blinded endpoint trial, Lancet Neurol, 16, 781, 10.1016/S1474-4422(17)30253-3 Campbell, 2018, Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke, N Engl J Med, 378, 1573, 10.1056/NEJMoa1716405 Schellinger, 2017, Another Enchantment From ENCHANTED (Enhanced Control of Hypertension and Thrombolysis Stroke Study): Are Savings and Safety More Salutary Than Efficacy?, Stroke, 48, 1720, 10.1161/STROKEAHA.117.017450 Luo, 2016, Intravenous Thrombolysis for Acute Ischemic Stroke in Patients Receiving Antiplatelet Therapy: A Systematic Review and Meta-analysis of 19 Studies, J Am Heart Assoc, 5 Tsivgoulis, 2017, Antiplatelet pretreatment and outcomes in intravenous thrombolysis for stroke: a systematic review and meta-analysis, J Neurol, 264, 1227, 10.1007/s00415-017-8520-1 Malhotra, 2020, Safety and efficacy of dual antiplatelet pretreatment in patients with ischemic stroke treated with IV thrombolysis: a systematic review and meta-analysis, Neurology, 94, e657, 10.1212/WNL.0000000000008961 Mazya, 2013, Safety of intravenous thrombolysis for ischemic stroke in patients treated with warfarin, Ann Neurol, 74, 266, 10.1002/ana.23924 Diener, 2017, Thrombolysis and thrombectomy in patients treated with dabigatran with acute ischemic stroke: expert opinion, Int J Stroke, 12, 9, 10.1177/1747493016669849 Touzé, 2018, Intravenous thrombolysis for acute ischaemic stroke in patients on direct oral anticoagulants, Eur J Neurol, 25, 747, 10.1111/ene.13582 Seiffge, 2017, Intravenous Thrombolysis in Patients with Stroke Taking Rivaroxaban Using Drug Specific Plasma Levels: Experience with a Standard Operation Procedure in Clinical Practice, J Stroke, 19, 347, 10.5853/jos.2017.00395 Tsivgoulis, 2017, Intravenous Thrombolysis in Acute Ischemic Stroke Patients Pretreated With Non-Vitamin K Antagonist Oral Anticoagulants: An Editorial Review, Stroke, 48, 2031, 10.1161/STROKEAHA.117.017206 Khatri, 2018, Effect of Alteplase vs Aspirin on Functional Outcome for Patients With Acute Ischemic Stroke and Minor Nondisabling Neurologic Deficits: The PRISMS Randomized Clinical Trial, JAMA, 320, 156, 10.1001/jama.2018.8496 IST-3 collaborative group, 2015, Association between brain imaging signs, early and late outcomes, and response to intravenous alteplase after acute ischaemic stroke in the third International Stroke Trial (IST-3): secondary analysis of a randomised controlled trial, Lancet Neurol, 14, 485, 10.1016/S1474-4422(15)00012-5 Patel, 2001, Lack of clinical significance of early ischemic changes on computed tomography in acute stroke, JAMA, 286, 2830, 10.1001/jama.286.22.2830 Kummer von, 1997, Acute stroke: usefulness of early CT findings before thrombolytic therapy, Radiology, 205, 327, 10.1148/radiology.205.2.9356611