Three dimensional macroporous hydroxyapatite/chitosan foam-supported polymer micelles for enhanced oral delivery of poorly soluble drugs

Lipinski, 2001, Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings, Adv. Drug Deliv. Rev., 46, 3, 10.1016/S0169-409X(00)00129-0 Kawabata, 2011, Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: basic approaches and practical applications, Int. J. Pharm., 420, 1, 10.1016/j.ijpharm.2011.08.032 Kaur, 2017, Freeze dried solid dispersion of exemestane: a way to negate an aqueous solubility and oral bioavailability problems, Eur. J. Pharm. Sci., 107, 54, 10.1016/j.ejps.2017.06.032 Meriskoliversidge, 2011, Nanosizing for oral and parenteral drug delivery: a perspective on formulating poorly-water soluble compounds using wet media milling technology, Adv. Drug. Deliv. Rev., 63, 427, 10.1016/j.addr.2010.12.007 Xu, 2013, Polymeric micelles, a promising drug delivery system to enhance bioavailability of poorly water-soluble drugs, J. Drug. Deliv., 2013, 1, 10.1155/2013/340315 Wu, 2011, Physical and chemical stability of drug nanoparticles, Adv. Drug. Deliv. Rev., 63, 456, 10.1016/j.addr.2011.02.001 Zeng, 2007, Silver nanoparticles directly formed on natural macroporous matrix and their anti-microbial activities, Nanotechnology, 18, 055605, 10.1088/0957-4484/18/5/055605 Sun, 2016, Applications of hierarchically structured porous materials from energy storage and conversion, catalysis, photocatalysis, adsorption, separation, and sensing to biomedicine, Chem. Soc. Rev., 47, 3479, 10.1039/C6CS00135A Zhang, 2014, Increasing the dissolution rate and oral bioavailability of the poorly water-soluble drug valsartan using novel hierarchical porous carbon monoliths, Int. J. Pharm., 473, 375, 10.1016/j.ijpharm.2014.07.024 Zhao, 2015, Investigation of 3D ordered macroporous carbon with different polymer coatings and their application as an oral vaccine carrier, Int. J. Pharm., 487, 234, 10.1016/j.ijpharm.2015.04.045 Zhao, 2011, Template-directed hydrothermal synthesis of hydroxyapatite as a drug delivery system for the poorly water-soluble drug carvedilol, Appl. Surf. Sci., 257, 10126, 10.1016/j.apsusc.2011.06.161 Atak, 2017, Preparation and characterization of amine functional nano-hydroxyapatite/chitosan bionanocomposite for bone tissue engineering applications, Carbohydr. Polym., 164, 200, 10.1016/j.carbpol.2017.01.100 Du, 2015, The design of pH-sensitive chitosan-based formulations for gastrointestinal delivery, Drug. Discov. Today, 20, 1004, 10.1016/j.drudis.2015.03.002 Wang, 2016, Mechanism of surface charge triggered intestinal epithelial tight junction opening upon chitosan nanoparticles for insulin oral delivery, Carbohydr. Polym., 157, 596, 10.1016/j.carbpol.2016.10.021 McClellan, 1998, Candesartan Cilexetil. A review of its use in essential hypertension, Drugs, 56, 847, 10.2165/00003495-199856050-00013 Schroden, 2002, Hybrid macroporous materials for heavy metal ion adsorption, J. Mater. Chem., 12, 3261, 10.1039/B204065B Higuchi, 1965, Vol. 4, 212 Cain, 2002, Flowability testing-an alternative technique for determining ANSI/CEMA standard 550 flowability ratings for granular materials, Powder Handl. Process., 14, 218 Emery, 2009, Flowability of moist pharmaceutical powders, Powder Technol., 189, 409, 10.1016/j.powtec.2008.06.017 Xie, 2012, Chitosan matrix with three dimensionally ordered macroporous structure for nimodipine release, Carbohydr. Polym., 4, 1648, 10.1016/j.carbpol.2012.07.045 Chen, 2002, Preparation and characterization of nano-sized hydroxyapatite particles and hydroxyapatite/chitosan nano-composite for use in biomedical materials, Mater. Lett., 57, 858, 10.1016/S0167-577X(02)00885-6 Rumondor, 2009, Phase behavior of poly(vinylpyrrolidone) containing amorphous solid dispersions in the presence of moisture, Mol. Pharm., 6, 1492, 10.1021/mp900050c Shen, 2010, Stabilized amorphous state of ibuprofen by co-spray drying with mesoporous SBA-15 to enhance dissolution properties, J. Pharm. Sci., 99, 1997, 10.1002/jps.21967 Vasconcelos, 2008, Solid dispersion as strategy to improve oral bioavailability of poof water soluble drugs, Drug Discov. Today, 12, 1068, 10.1016/j.drudis.2007.09.005 Gao, 2004, Enhanced oral bioavailability of a poorly water soluble drug PNU-91325 by supersaturatable formulations, Drug. Dev. Ind. Pharm., 30, 221, 10.1081/DDC-120028718 Agnihotri, 2004, Recent advances on chitosan-based micro- and nanoparticles in drug delivery, J. Controlled Release, 100, 5, 10.1016/j.jconrel.2004.08.010 Kumari, 2010, Biodegradable polymeric nanoparticles based drug delivery systems, Colloids Surf. B. Biointerfaces, 75, 1, 10.1016/j.colsurfb.2009.09.001