Therapierefraktäres kolorektales Karzinom mit KRAS-G12C-Mutation

Milan Hartmann, Hakan Alakus

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Tài liệu tham khảo

Salem M, El-Refai S, Sha W et al (2021) Characterization of KRAS mutation variants and prevalence of KRAS-G12C in gastrointestinal malignancies. ESMO Congress 2021, virtual meeting, September 16–21

Patelli G, Tosi F, Amatu A, Mauri G, Curaba A, Patanè DA, Pani A, Scaglione F, Siena S, Sartore-Bianchi A (2021) Strategies to tackle RAS-mutated metastatic colorectal cancer. Esmo Open 6(3):100156. https://doi.org/10.1016/j.esmoop.2021.100156

Yaeger R, Weiss J, Pelster MS, Spira AI, Barve M, Ou SI, Leal TA, Bekaii-Saab TS, Paweletz CP, Heavey GA, Christensen JG, Velastegui K, Kheoh T, Der-Torossian H, Klempner SJ (2023) Adagrasib with or without cetuximab in colorectal cancer with mutated KRAS G12C. N Engl J Med 388(1):44–54. https://doi.org/10.1056/NEJMoa2212419