Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

Nature - Tập 432 Số 7014 - Trang 173-178 - 2004
Jürgen Soutschek1, Akin Akinc, Birgit Bramlage, Klaus Charissé, Rainer Constien, Mary Donoghue, Sayda M. Elbashir, Anke Geick, Philipp Hadwiger, Jens Harborth, Matthias John, Venkitasamy Kesavan, Gary Lavine, Rajendra K. Pandey, Timothy Racie, Kallanthottathil G. Rajeev, Ingo Röhl, Iva Toudjarska, Gang Wang, Silvio Wuschko, David Bumcrot, Victor Koteliansky, Stefan Limmer, Muthiah Manoharan, Hans‐Peter Vornlocher
1Alnylam Europe AG, Fritz-Hornschuch-Str. 9, 95326 Kulmbach, Germany. [email protected]

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