Therapeutic effect of multifunctional celastrol nanoparticles with mitochondrial alkaline drug release in breast cancer

Materials Today Advances - Tập 17 - Trang 100328 - 2023
Yanru Qin1, Zhongjie Wang1, Xueyuan Wang2, Tianyu Zhang1, Yixue Hu2, Dongna Wang1, Hui Sun1, Liefeng Zhang1, Yongqiang Zhu1,2
1School of Food and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, 210023, China
2College of Life Science, Nanjing Normal University, Nanjing 210023, China

Tài liệu tham khảo

Siegel, 2021, Cancer statistics, 2021, CA. Cancer, J. Clin., 71, 7 Viale, 2020, The American cancer society's facts & figures: 2020 edition, J. Adv. Pract. Oncol., 11, 135 Taghian, 2014, Lymphedema following breast cancer treatment and impact on quality of life: a review, Crit. Rev. Oncol.-Hematol., 92, 227, 10.1016/j.critrevonc.2014.06.004 Wagh, 2021, Nanotechnology-Based celastrol formulations and their therapeutic applications, Front. Pharmacol., 12, 10.3389/fphar.2021.673209 Zuo, 2019, Tripterine inhibits proliferation, migration and invasion of breast cancer MDA-MB-231 cells by up-regulating microRNA-15a, Biol. Chem., 10.1515/hsz-2018-0469 Shrivastava, 2015, Anticancer effect of celastrol on human triple negative breast cancer: possible involvement of oxidative stress, mitochondrial dysfunction, apoptosis and PI3K/Akt pathways, Exp. Mol. Pathol., 98, 313, 10.1016/j.yexmp.2015.03.031 Yang, 2019, Preparation, characterization and cytotoxic evaluation of inclusion complexes between celastrol with polyamine-modified β-cyclodextrins, J. Incl. Phenom. Macro., 95, 147, 10.1007/s10847-019-00933-7 Lamb, 2014, Mitochondria as new therapeutic targets for eradicating cancer stem cells: quantitative proteomics and functional validation via MCT1/2 inhibition, Oncotarget, 5, 11029, 10.18632/oncotarget.2789 Singh, 2019, Induction of mitochondrial cell death and reversal of anticancer drug resistance via nanocarriers composed of a triphenylphosphonium derivative of tocopheryl polyethylene glycol succinate, Mol. Pharm., 16, 3744, 10.1021/acs.molpharmaceut.9b00177 Shi, 2020, Celastrol: a review of useful strategies overcoming its limitation in anticancer application, Front. Pharmacol., 11, 10.3389/fphar.2020.558741 Chan, 2020, Mitochondrial dynamics and its involvement in disease, Annu. Rev. Pathol., 15, 235, 10.1146/annurev-pathmechdis-012419-032711 Wang, 2020, Tumor- and mitochondria-targeted nanoparticles eradicate drug resistant lung cancer through mitochondrial pathway of apoptosis, J. Nanobiotechnol., 18, 8, 10.1186/s12951-019-0562-3 De Francesco, 2019, Dodecyl-TPP targets mitochondria and potently eradicates cancer stem cells (CSCs): synergy with FDA-approved drugs and natural compounds (vitamin C and berberine), Front. Oncol., 9, 615, 10.3389/fonc.2019.00615 Lee, 2021, Triphenylphosphonium-conjugated glycol chitosan microspheres for mitochondria-targeted drug delivery, Int. J. Biol. Macromol., 167, 35, 10.1016/j.ijbiomac.2020.11.129 Alexis, 2008, Factors affecting the clearance and biodistribution of polymeric nanoparticles, Mol. Pharm., 5, 505, 10.1021/mp800051m Wang, 2013, Metabolism of nanomaterials in vivo: blood circulation and organ clearance, Acc. Chem. Res., 46, 761, 10.1021/ar2003336 Poon, 2019, Elimination pathways of nanoparticles, ACS Nano, 13, 5785, 10.1021/acsnano.9b01383 Lin, 2021, Self-assembled nanomedicine combining a berberine derivative and doxorubicin for enhanced antitumor and antimetastatic efficacy via mitochondrial pathways, Nanoscale, 13, 6605, 10.1039/D1NR00032B Marverti, 2021, Folic acid-peptide conjugates combine selective cancer cell internalization with thymidylate synthase dimer interface targeting, J. Med. Chem., 64, 3204, 10.1021/acs.jmedchem.0c02107 Tan, 2018, Mitochondrial alkaline pH-responsive drug release mediated by Celastrol loaded glycolipid-like micelles for cancer therapy, Biomaterials, 154, 169, 10.1016/j.biomaterials.2017.07.036 Zhang, 2020, Stepwise dual targeting and dual responsive polymer micelles for mitochondrion therapy, J. Contr. Release, 322, 157, 10.1016/j.jconrel.2020.03.011 Duan, 2022, Self-activated cascade biocatalysis of glucose oxidase-polycation-iron nanoconjugates augments cancer immunotherapy, ACS Appl. Mater. Interfaces, 10.1021/acsami.2c04894 Yu, 2020, ROS-responsive nano-drug delivery system combining mitochondria-targeting ceria nanoparticles with atorvastatin for acute kidney injury, Theranostics, 10, 2342, 10.7150/thno.40395 Lou, 2022, A small-molecule based organic nanoparticle for photothermal therapy and near-infrared-IIb imaging, ACS Appl. Mater. Interfaces, 14, 35454, 10.1021/acsami.2c11706 Babij, 2016, NMR chemical shifts of trace impurities: industrially preferred solvents used in process and green chemistry, Org. Process Res. Dev., 20, 661, 10.1021/acs.oprd.5b00417 Hillaireau, 2009, Nanocarriers' entry into the cell: relevance to drug delivery, Cell. Mol. Life Sci. : CMLS., 66, 2873, 10.1007/s00018-009-0053-z Wang, 2021, pH-activated, mitochondria-targeted, and redox-responsive delivery of paclitaxel nanomicelles to overcome drug resistance and suppress metastasis in lung cancer, J. Nanobiotechnol., 19, 152, 10.1186/s12951-021-00895-4 Contreras-Ruiz, 2011, Intracellular trafficking of hyaluronic acid-chitosan oligomer-based nanoparticles in cultured human ocular surface cells, Mol. Vis., 17, 279 Torchilin, 2001, TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors, Proc. Natl. Acad. Sci. USA, 98, 8786, 10.1073/pnas.151247498 Christian, 1997, Use of cyclodextrins for manipulating cellular cholesterol content, J. Lipid Res., 38, 2264, 10.1016/S0022-2275(20)34940-3 Petrov, 2011, Increased non-quantal release of acetylcholine after inhibition of endocytosis by methyl-β-cyclodextrin: the role of vesicular acetylcholine transporter, Neuroscience, 186, 1, 10.1016/j.neuroscience.2011.04.051 Wang, 1993, Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation, J. Cell Biol., 123, 1107, 10.1083/jcb.123.5.1107 Perisa, 2016, Itinerary of high density lipoproteins in endothelial cells, Biochim. Biophys. Acta, 1861, 98, 10.1016/j.bbalip.2015.11.004 Sreedurgalakshmi, 2021, Cetuximab-siRNA conjugate linked through cationized gelatin knocks down KRAS G12C mutation in NSCLC sensitizing the cells toward gefitinib, Technol. Cancer Res. Treat., 20, 10.1177/15330338211041453 Yamada, 2015, Catabolism of chondroitin sulfate, Cell. Mol. Biol. Lett., 20, 196, 10.1515/cmble-2015-0011 Prabhakar, 2006, The biosynthesis and catabolism of galactosaminoglycans, Adv. Pharmacol., 53, 69, 10.1016/S1054-3589(05)53005-9 Li, 2020, Rational construction of a mitochondrial targeting, fluorescent self-reporting drug-delivery platform for combined enhancement of endogenous ROS responsiveness, ACS Appl. Mater. Interfaces, 12, 32432, 10.1021/acsami.0c08336 Chang, 2020, Mitochondrial ROS1 increases mitochondrial fission and respiration in oral squamous cancer carcinoma, Cancers, 12, 10.3390/cancers12102845 Zhao, 2021, A multifunctional nano-delivery system enhances the chemo-co-phototherapy of tumor multidrug resistance via mitochondrial-targeting and inhibiting P-glycoprotein-mediated efflux, J. Mater. Chem. B., 9, 9174, 10.1039/D1TB01658J Mao, 2013, Perfluorooctane sulfonate induces apoptosis in lung cancer A549 cells through reactive oxygen species-mediated mitochondrion-dependent pathway, J. Appl. Toxicol., 33, 1268, 10.1002/jat.2785 Cai, 2022, Aperture modulation of isoreticular metal organic frameworks for targeted antitumor drug delivery, ACS Appl. Mater. Interfaces Zhao, 2018, Ligustrazine suppresses neuron apoptosis via the Bax/Bcl-2 and caspase-3 pathway in PC12 cells and in rats with vascular dementia, IUBMB Life, 70, 60, 10.1002/iub.1704