Therapeutic angiogenesis for critical limb ischemia

Norgen, 2007, Inter-society consensus for the management of peripheral arterial disease (TASC II), J Vasc Surg, 45, S5, 10.1016/j.jvs.2006.12.037 Selvin, 2004, Prevalence of and risk factors for peripheral arterial disease in the United States: results from the National Health and Nutrition Examination Survey, 1999−2000, Circulation, 10, 738, 10.1161/01.CIR.0000137913.26087.F0 Lepantalo, 1996, Outcome of unreconstructed chronic critical leg ischemia, Eur J Vasc Endovasc Surg, 11, 153, 10.1016/S1078-5884(96)80044-X Dormandy, 1999, The fate of patients with critical leg ischemia, Semin Vasc Surg, 12, 142 Powell, 2012, Update on clinical trials evaluating the effect of biologic therapy in patients with critical limb ischemia, J Vasc Surg, 56, 264, 10.1016/j.jvs.2012.03.255 1999, Prostanoids for chronic critical limb ischemia. A randomized, controlled, open-label trial with prostaglandin E1. The ICAI Study Group. Ischemia Cronica degli Arti Inferiori, Ann Intern Med, 130, 412, 10.7326/0003-4819-130-5-199903020-00005 Brass, 2006, Parenteral therapy with lipo-ecrapost, a lipid based formulation of a PGE1 analog does not alter six-month outcomes in patients with critical limb ischemia, J Vasc Surg, 43, 752, 10.1016/j.jvs.2005.11.041 Spincemaille, 2001, The results of spinal chord stimulation in critical limb ischemia. A review, Eur J Vasc Endovasc Surg, 21, 99, 10.1053/ejvs.2000.1291 Shimamura, 2013, Gene therapy and cell-based therapies for therapeutic angiogenesis in peripheral artery disease, Biomed Res Int, 2013, 1, 10.1155/2013/186215 Shweiki, 1992, Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis, Nature, 359, 843, 10.1038/359843a0 Comerata, 2002, Naked plasmid DNA encoding fibroblast growth factor type 1 for the treatment of end-stage unreconstructable lower extremity ischemia: preliminary results of a phase I trial, J Vasc Surg, 35, 930, 10.1067/mva.2002.123677 Palmer-Kazen, 2004, Vascular endothelial cell growth factor and fibroblast growth factor 2 expression in patients with critical limb ischemia, J Vasc Surg, 39, 621, 10.1016/j.jvs.2003.07.006 Shigematsu, 2010, Randomized, double-blind, placebo-controlled clinical trial of hepatocyte growth factor plasmid for critical limb ischemia, Gene Ther, 17, 1152, 10.1038/gt.2010.51 Powell, 2010, Safety and efficacy of patient specific intramuscular injection of HGF plasmid gene therapy on limb perfusion and wound healing in patients with ischemic lower extremity ulceration: results of the HGF-0205 trial, J Vasc Surg, 52, 1525, 10.1016/j.jvs.2010.07.044 Morishita, 2011, Hepatocyte growth factor gene transfer to treat critical limb ischemia, Arterioscler Thromb Vasc Biol, 31, 713, 10.1161/ATVBAHA.110.219550 Fowkes, 2011, Gene therapy for critical limb ischemia: the TAMARIS trial, Lancet, 377, 1894, 10.1016/S0140-6736(11)60441-8 Powell, 2008, Results of a double-blind, placebo-controlled study to assess the safety of intramuscular injection of hepatocyte growth factor plasmid to improve limb perfusion in patients with critical limb ischemia, Circulation, 118, 58, 10.1161/CIRCULATIONAHA.107.727347 Liew, 2012, Therapeutic potential for mesenchymal stem cell transplantation for critical limb ischemia, Stem Cell Res Ther, 3, 28, 10.1186/scrt119 Chamberlain, 2007, Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing, Stem Cells, 25, 2739, 10.1634/stemcells.2007-0197 Asahara, 1997, Isolation of putative progenitor endothelial cells for angiogenesis, Science, 275, 964, 10.1126/science.275.5302.964 Pittenger, 1999, Multilineage potential of adult human mesenchymal stem cells, Science, 284, 143, 10.1126/science.284.5411.143 Ko, 2011, The role of stem cells in cutaneous wound healing: what do we really know?, Plast Reconstr Surg, 127, 10S, 10.1097/PRS.0b013e3181fbe2d8 Kasper, 2007, Mesenchymal stem cells regulate angiogenesis according to their mechanical environment, Stem Cells, 25, 903, 10.1634/stemcells.2006-0432 Grayson, 2007, Hypoxia enhances proliferation and tissue formation of human mesenchymal stem cells, Biochem Biophys Res Commun, 358, 948, 10.1016/j.bbrc.2007.05.054 Kalka, 2000, Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization, Proc Natl Acad Sci U S A, 97, 3422, 10.1073/pnas.97.7.3422 Aicher, 2003, Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells, Nat Med, 9, 1370, 10.1038/nm948 Shintani, 2001, Augmentation of postnatal neovascularization with autologous bone marrow transplantation, Circulation, 103, 897, 10.1161/01.CIR.103.6.897 Tateishi-Yuyama, 2002, Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial, Lancet, 360, 427, 10.1016/S0140-6736(02)09670-8 Matoba, 2008, Long-term clinical outcome after intramuscular implantation of bone marrow mononuclear cells (Therapeutic Angiogenesis by Cell Transplantation [TACT] trial) in patients with chronic limb ischemia, Am Heart J, 156, 1010, 10.1016/j.ahj.2008.06.025 Walter, 2010, Intraarterial administration of bone marrow mononuclear cells in patients with critical limb ischemia: a randomized-start, placebo-controlled pilot trial (PROVASA), Circ Cardiovasc Interv, 4, 26, 10.1161/CIRCINTERVENTIONS.110.958348 Ledford, 2013, Potential beneficial effects of ixmyelocel-T in the treatment of atherosclerotic diseases, Stem Cell Res Ther, 4, 135, 10.1186/scrt346 Powell, 2012, Interim analysis results from the RESTORE-CLI, a randomized, double-blind multicenter phase II trial comparing expanded autologous bone marrow-derived tissue repair cells and placebo in patients with critical limb ischemia, J Vasc Surg, 54, 1032, 10.1016/j.jvs.2011.04.006 Benoit, 2011, The role of amputation as an outcome measure in cellular therapy for critical limb ischemia: implications for clinical trial design, J Transl Med, 9, 165, 10.1186/1479-5876-9-165 Iafrati, 2011, Early results and lessons learned from a multicenter, randomized, double-blind trial of bone marrow aspirate concentrate in critical limb ischemia, J Vasc Surg, 54, 1650, 10.1016/j.jvs.2011.06.118 Chung, 2014, The need for improved risk stratification in chronic limb ischemia, J Vasc Surg, 10.1016/j.jvs.2014.07.104 Adam, 2005, Bypass versus angioplasty in severe ischaemia of the leg (BASIL): multicentre, randomised controlled trial, Lancet, 366, 1925, 10.1016/S0140-6736(05)67704-5 Teraa, 2013, Autologous bone marrow-derived cell therapy in patients with critical limb ischemia: a meta-analysis of randomized controlled clinical trials, Ann Surg, 258, 922, 10.1097/SLA.0b013e3182854cf1 Tomita, 2003, Angiogenic property of hepatocyte growth factor is dependent on upregulation of essential transcription factor for angiogenesis, ets-1, Circulation, 107, 1411, 10.1161/01.CIR.0000055331.41937.AA