Theories of Blood Coagulation

Journal of Pediatric Oncology Nursing - Tập 24 Số 3 - Trang 123-131 - 2007
James Riddel1, Bradley E. Aouizerat2, Christine Miaskowski3, David Lillicrap4
1Division of Hematology at Children's Hospital and Research Center Oakland, Oakland, California 94609-1809, USA. [email protected]
2Department of Physiological Nursing & Institute for Human Genetics at the University of California, San Francisco
3Department of Physiological Nursing at the University of California, San Francisco
4Department of Pathology & Molecular Medicine at Queen's University, Kingston, Ontario, Canada

Tóm tắt

Although the concept of the coagulation cascade represented a significant advance in the understanding of coagulation and served for many years as a useful model, more recent clinical and experimental observations demonstrate that the cascade/waterfall hypothesis does not fully and completely reflect the events of hemostasis in vivo. The goal of this article is to review the evolution of the theories of coagulation and their proposed models to serve as a tool when reviewing the research and practice literature that was published in the context of these different theories over time.

Từ khóa


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Thông tin xuất bản

Journal of Pediatric Oncology Nursing

Tập 24 Số 3

123-131

Thông tin tác giả