The zebrafish embryo model in environmental risk assessment—applications beyond acute toxicity testing
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Alexander JB, Ingram GA (1992) Noncellular nonspecific defence mechanisms of fish. Annu Rev Fish Dis 2:249–279
Amanuma K, Takeda H, Amanuma H, Aoki Y (2000) Transgenic zebrafish for detecting mutations caused by compounds in aquatic environments. Nat Biotechnol 18:62–65
Ankley GT, Daston GP, Degitz SJ, Denslow ND, Hoke RA, Kennedy SW, Miracle AL, Perkins EJ, Snape J, Tillitt DE, Tyler CR, Versteeg D (2006) Toxicogenomics in regulatory ecotoxicology. Environ Sci Technol 40:4055–4065
Bachmann J (2002) Entwicklung und Erprobung eines Teratogenitäts-Screening-Testes mit Embryonen des Zebrabärblings Danio rerio. PhD Thesis, TU Dresden
Bard SM (2000) Multixenobiotic resistance as a cellular defense mechanism in aquatic organisms. Aquat Toxicol 48:357–389
Bhogal N (2005) The EU REACH system: blessing in disguise or wolf in wolf’s clothing? ATLA Altern Lab Anim 33:81–82
Blechinger SR, Kusch RC, Haugo K, Matz C, Chivers DP, Krone PH (2007) Brief embryonic cadmium exposure induces a stress response and cell death in the developing olfactory system followed by long-term olfactory deficits in juvenile zebrafish. Toxicol Appl Pharmacol 224(1):72–80
Bols NC, Brubacher JL, Ganassin RC, Lee LEJ (2001) Ecotoxicology and innate immunity in fish. Dev Comp Immunol 25:853–873
Braunbeck T, Lammer E (2005) Draft detailed review paper on fish embryo toxicity assays. Report prepared for the German Federal Environmental Agency (UBA Contract Number 203 85 422)
Braunbeck T, Boettcher M, Hollert H, Kosmehl T, Lammer E, Leist E, Rudolf M, Seitz N (2005) Towards an alternative for the acute fish LC(50) test in chemical assessment: the fish embryo toxicity test goes multi-species—an update. ALTEX 22:87–102
Breithaupt H (2006) The costs of REACH. REACH is largely welcomed, but the requirement to test existing chemicals for adverse effects is not good news for all. EMBO Rep 7:968–971
Burns CG, MacRae CA (2006) Purification of hearts from zebrafish embryos. Biotechniques 40:274, 276, 278 passim
Carney S, Peterson R, Heideman W (2004) 2,3,7,8-Tetrachlorodibenzo-p-dioxin activation of the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator pathway causes developmental toxicity through a CYP1A-independent mechanism in zebrafish. Mol Pharmacol 66:512–521
Carney SA, Chen J, Burns CG, Xiong KM, Peterson RE, Heideman W (2006) Aryl hydrocarbon receptor activation produces heart-specific transcriptional and toxic responses in developing zebrafish. Mol Pharmacol 70:49–61
Cheng J, Flahaut E, Cheng SH (2007) Effect of carbon nanotubes on developing zebrafish (Danio rerio) embryos. Environ Toxicol Chem 26:708–716
Commission of the European Communities (1967) Council Directive 67/548/EEC of 18 August 1967 on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances. Official Journal of the European Communities L96/1
Commission of the European Communities (1986) Council Directive 86/609/EEC of 24 November 1986 on the approximation of laws, regulations and administrative provisions of the Member States regarding the protection of animals used for experimental and other scientific purposes. Official Journal L 358 , 18/12/1986 P. 0001–0028
Commission of the European Communities (1991) Council Directive 91/414/EEC of 15 July 1991 concerning the placing of plant protection products on the market. Official Journal of the European Communities L 230/1
Commission of the European Communities (1992) Council Directive 92/32/EEC of 30 April 1992 amending for the seventh time Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances
Commission of the European Communities (1993a) Council Regulation 793/93/EEC of 23 March 1993 on the evaluation and control of risks of existing substances. Official Journal of the European Communities L84/1
Commission of the European Communities (1993b) Commission Directive 93/67/EEC of 20 July 1993, laying down the principles for assessment of risks to man and the environment of substances notified in accordance with Council Directive 67/548/EEC. Official Journal of the European Communities L227/9
Commission of the European Communities (1994) Regulation 1488/94/EEC of 28 June 1994, laying down the principles for the assessment of risks to man and the environment of existing substances in accordance with Council Regulation 793/93/EEC. Official Journal of the European Communities L161/3
Connell DW, Hawker DW (1988) Use of polynomial expressions to describe the bioconcentration of hydrophobic chemicals by fish. Ecotoxicol Environ Saf 16:242–257
Cordon-Cardo C, O’Brien JP, Boccia J, Casals D, Bertino JR, Melamed MR (1990) Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues. J Histochem Cytochem 38:1277–1287
Corvi R et al (2006) Meeting report—validation of toxicogenomics-based test systems: ECVAM-ICCVAM/NICEATM considerations for regulatory use. Environ Health Perspect 114:420–429
Coverdale LE, Lean D, Martin CC (2004) Not just a fishing trip—Environmental genomics using zebrafish. Current Genomics 5:395–407
Cowan KJ, Storey KB (2003) Mitogen-activated protein kinases: new signaling pathways functioning in cellular responses to environmental stress. J Exp Biol 206:1107–1115
Creton R (2004) The calcium pump of the endoplasmic reticulum plays a role in midline signaling during early zebrafish development. Brain Res Dev Brain Res 151:33–41
CVMP/VICH (2000) Guideline on environmental impact assessment (EIAS) for veterinary medicinal products—phase I. VICH Topic GL6 (Ecotoxicity Phase I) Step 7 (CVMP/VICH/592/98)
de Longueville F, Bertholet V, Remacle J (2004) DNA microarrays as a tool in toxicogenomics. Comb Chem High Throughput Screen 7:207–211
Dean M, Annilo T (2005) Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates. Annu Rev Genomics Hum Genet 6:123–142
Eaton RC, Farley RD (1974) Spawning cycle and egg production of zebrafish, Brachydanio rerio, in the laboratory. Copeia 1:195–209
EMEA/CHMP (2006) Guideline on the environmental risk assessment of medicinal products for human use. Doc. ref. EMEA/CHMP/SWP/4447/00
Federal Law Gazette (2005) Volume 2005 Part I No. 5, published in Bonn on 01. 25.2005. Announcement of the amendment of the Wastewater Charges Act on the 18th January 2005 [Bundesgesetzblatt (2005). Jahrgang 2005 Teil I Nr. 5, ausgegeben zu Bonn am 25.01.2005. Bekanntmachung der Neufassung des Abwasserabgabengesetzes vom 18. Januar 2005]
Fischer S (2007) Nachweis der Expression und Aktivität von ABC-Xenobiotika-Transportern in Embryonen des Zebrabärblings. Diploma thesis, Martin-Luther-University of Halle-Wittenberg. Division of Biochemistry/Biotechnology
Fleming A (2007) Zebrafish as an alternative model organism for disease modelling and drug discovery: implications for the 3Rs. NC3Rs, Iss. 10, National Centre for the Replacement, Refinement and Reduction of Animals in research, www.nc3rs.org.uk
Fraysse B, Mons R, Garric J (2006) Development of a zebrafish 4-day embryo-larval bioassay to assess toxicity of chemicals. Ecotoxicol Environ Saf 63:253–267
Goldsmith P (2004) Zebrafish as a pharmacological tool: the how, why and when. Curr Opin Pharmacol 4:504–512
Gorge G, Nagel R (1990) Kinetics and metabolism of 14c-lindane and 14c-atrazine in early life stages of zebrafish (Brachydanio-Rerio). Chemosphere 21:1125–1137
Gulati-Leekha A, Goldman D (2006) A reporter-assisted mutagenesis screen using [alpha]1-tubulin-GFP transgenic zebrafish uncovers missteps during neuronal development and axonogenesis. Dev Biol 296:29–47
Gündel U, Benndorf D, von Bergen M, Altenburger R, Küster E (2007) Vitellogenin cleavage products as indicators for toxic stress in zebra fish embryos: a proteomic approach. Proteomics 7:4541–4554
Herbomel P, Thisse B, Thisse C (1999) Ontogeny and behaviour of early macrophages in the zebrafish embryo. Development 126:3735–3745
Higgins CF (2007) Multiple molecular mechanisms for multidrug resistance transporters. Nature 446:749–757
Hill A, Howard CV, Strahle U, Cossins A (2003) Neurodevelopmental defects in zebrafish (Danio rerio) at environmentally relevant dioxin (TCDD) concentrations. Toxicol Sci 76:392–399
Hill AJ, Teraoka H, Heideman W, Peterson RE (2005) Zebrafish as a model vertebrate for investigating chemical toxicity. Toxicol Sci 86:6–19
Hoyt PR, Doktycz MJ, Beattie KL, Greeley MS (2003) DNA microarrays detect 4-nonylphenol-induced alterations in gene expression during zebrafish early development. Ecotoxicology 12:469–474
Incardona JP, Day HL, Collier TK, Scholz NL (2006) Developmental toxicity of 4-ring polycyclic aromatic hydrocarbons in zebrafish is differentially dependent on AH receptor isoforms and hepatic cytochrome P4501A metabolism. Toxicol Appl Pharmacol 217:308–321
Kimmel CB, Ballard WW, Kimmel SR, Ullmann B, Schilling TF (1995) Stages of embryonic development of the zebrafish. Dev Dyn 203:253–310
Konemann H, van Leeuwen K (1980) Toxicokinetics in fish: accumulation and elimination of six chlorobenzenes by guppies. Chemosphere 9:3–19
Kosmehl T, Hallare AV, Reifferscheid G, Manz W, Braunbeck T, Hollert H (2006) A novel contact assay for testing genotoxicity of chemicals and whole sediments in zebrafish embryos. Environ Toxicol Chem 25:2097–2106
Kosmehl T, Krebs F, Manz W, Braunbeck T, Hollert H (2007) Differentiation between bioavailable and total hazard potential of sediment-induced DNA fragmentation as measured by the comet assay with zebrafish embryos. J Soils Sediments 7:377–387
Kosmehl T (2007) Molecular biomarkers in zebrafish embryos—towards a more realistic approach in sediment assessment. PhD thesis, University of Heidelberg, Institute of Zoology
Kurelec B (1997) A new type of hazardous chemical: the chemosensitizers of multixenobiotic resistance. Environ Health Perspect 105(Suppl 4):855–860
Küster E, Altenburger R (2007) Suborganismic and organismic effects of aldicarb and its metabolite aldicarb-sulfoxide to the zebrafish embryo (Danio rerio). Chemosphere 68:751–760
Legler J, Zeinstra LM, Schuitemaker F, Lanser PH, Bogerd J, Brouwer A, Vethaak AD, De Voogt P, Murk AJ, Van der Burg B (2002) Comparison of in vivo and in vitro reporter gene assays for short-term screening of estrogenic activity. Environ Sci Technol 36:4410–4415
Lemeer S, Jopling C, Naji F, Ruijtenbeek R, Slijper M, Heck AJ, den Hertog J (2007) Protein-tyrosine kinase activity profiling in knock down zebrafish embryos. PLoS ONE 2:e581
Leslie EM, Deeley RG, Cole SP (2001) Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters. Toxicology 167:3–23
Leslie EM, Deeley RG, Cole SP (2005) Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense. Toxicol Appl Pharmacol 204:216–237
Mattingly CJ, McLachlan JA, Toscano WA Jr (2001) Green fluorescent protein (GFP) as a marker of aryl hydrocarbon receptor (AhR) function in developing zebrafish (Danio rerio). Environ Health Perspect 109:845–849
Mitchelmore CL, Chipman JK (1998) DNA strand breakage in aquatic organisms and the potential value of the comet assay in environmental monitoring. Mutat Research-Fund Mol M 399:135–147
Muncke J, Eggen RI (2006) Vitellogenin 1 mRNA as an early molecular biomarker for endocrine disruption in developing zebrafish (Danio rerio). Environ Toxicol Chem 25:2734–2741
Muncke J, Junghans M, Eggen R (2007) Testing estrogenicity of known and novel (xeno-)estrogens in the MolDarT using developing zebrafish Danio rerio. Environ Toxicol 22:185–193
Nagel R (2002) DarT: The embryotest with the zebrafish Danio rerio—a general model in ecotoxicology and toxicology. ALTEX 19(Suppl 1/02):38–48
Newman JW, Denton DL, Morisseau C, Koger CS, Wheelock CE, Hinton DE, Hammock BD (2001) Evaluation of fish models of soluble epoxide hydrolase inhibition. Environ Health Perspect 109:61–66
OECD (2006) Fish embryo toxicity (FET) test. Draft OECD guideline for the testing of chemicals, http://www.oecd.org/dataoecd/39/59/36817070.pdf
OSPAR—Convention for the Protection of the Marine Environment of the North-East Atlantic (2000) Background document concerning the elaboration of programmes and measures relating to whole effluent assessment. Report 117; London: OSPAR
Parng C, Seng WL, Semino C, McGrath P (2002) Zebrafish: a preclinical model for drug screening. Assay Drug Dev Technol 1:41–48
Pelster B (2002) Developmental plasticity in the cardiovascular system of fish, with special reference to the zebrafish. Comp Biochem Phys A 133:547–553
Podrabsky JE, Lopez JP, Fan TWM, Higashi R, Somero GN (2007) Extreme anoxia tolerance in embryos of the annual killifish Austrofundulus limnaeus: insights from a metabolomics analysis. J Exp Biol 210:2253–2266
Pressley ME, Phelan PE 3rd, Witten PE, Mellon MT, Kim CH (2005) Pathogenesis and inflammatory response to Edwardsiella tarda infection in the zebrafish. Dev Comp Immunol 29:501–513
Ratte HT, Hammers-Wirtz M (2003) Evaluation of the existing data base from the fish embryo test. UBA (German Federal Environmental Agency) report under contract no363 01 062
Rubinstein AL (2003) Zebrafish: from disease modeling to drug discovery. Curr Opin Drug Discov Dev 6:218–223
Schirmer K (2006) Proposal to improve vertebrate cell cultures to establish them as substitutes for the regulatory testing of chemicals and effluents using fish. Toxicology 224:163–183
Schreiber R, Altenburger R, Paschke A, Schüürmann G, Küster E (2008) A novel system for the determination of bioconcentration and internal dose in embryos of the zebrafish (Danio rerio) (in prep)
Seok S-H, Baek M-W, Lee H-Y, Kim D-J, Na Y-R, Noh K-J, Park S-H, Lee H-K, Lee B-H, Ryu D-Y, Park J-H (2007) Quantitative GFP fluorescence as an indicator of arsenite developmental toxicity in mosaic heat shock protein 70 transgenic zebrafish. Toxicol Appl Pharmacol 225(2):154–161
Shrader EA, Henry TR, Greeley MS Jr, Bradley BP (2003) Proteomics in zebrafish exposed to endocrine disrupting chemicals. Ecotoxicology 12:485–488
Smital T, Luckenbach T, Sauerborn R, Hamdoun AM, Vega RL, Epel D (2004) Emerging contaminants–pesticides, PPCPs, microbial degradation products and natural substances as inhibitors of multixenobiotic defense in aquatic organisms. Mutat Res 552:101–117
Snape JR, Maund SJ, Pickford DB, Hutchinson TH (2004) Ecotoxicogenomics: the challenge of integrating genomics into aquatic and terrestrial ecotoxicology. Aquat Toxicol 67:143–154
Tay T, Lin Q, Seow T, Tan K, Hew C, Gong Z (2006) Proteomic analysis of protein profiles during early development of the zebrafish, Danio rerio. Proteomics 6:3176–3188
Ton C, Stamatiou D, Liew C-C (2003) Gene expression profile of zebrafish exposed to hypoxia during development. Physiol Genomics 13:97–106
Turner MA, Viant MR, Teh SJ, Johnson ML (2007) Developmental rates, structural asymmetry, and metabolic fingerprints of steelhead trout (Oncorhynchus mykiss) eggs incubated at two temperatures. Fish Physiol Biochem 33:59–72
Tyler CR, Jobling S, Sumpter JP (1998) Endocrine disruption in wildlife—a critical review of the evidence. Crit Rev Toxicol 28:319–361
van der Sar AM, Musters RJP, van Eeden FJM, Appelmelk BJ, Vandenbroucke-Grauls CMJE, Bitter W (2003) Zebrafish embryos as a model host for the real time analysis of Salmonella typhimurium infections. Cell Microbiol 5:601–611
van der Sar AM, Appelmelk BJ, Vandenbroucke-Grauls CM, Bitter W (2004) A star with stripes: zebrafish as an infection model. Trends Microbiol 12:451–457
Viant MR, Pincetich CA, Eerderna RST (2006a) Metabolic effects of dinoseb, diazinon and esfenvalerate in eyed eggs and alevins of Chinook salmon (Oncorhynchus tshawytscha) determined by H-1 NMR metabolomics. Aquat Toxicol 77:359–371
Viant MR, Pincetich CA, Hinton DE, Tjeerdema RS (2006b) Toxic actions of dinoseb in medaka (Oryzias latipes) embryos as determined by in vivo 31P NMR, HPLC-UV and 1H NMR metabolomics. Aquat Toxicol 76:329–342
VICH (2004) The European Agency for the Evaluation of Medicinal Products: environmental impact assessment for veterinary medicinal products. Phase II guidance. VICH Topic GL 38 (Ecotoxicity Phase II) Step 7 (CVMP/VICH/790/03-Final)
Voelker D, Vess C, Tillmann M, Nagel R, Otto GW, Geisler R, Schirmer K, Scholz S (2007) Differential gene expression as a toxicant-sensitive endpoint in zebrafish embryos and larvae. Aquat Toxicol 81:355–364
Voelker D, Stetefeld N, Schirmer K, Scholz S (2008) The role of cyp1a and heme oxygenase 1 gene expression for the toxicity of 3,4-dichloroaniline in zebrafish (Danio rerio) embryos. Aquat Toxicol 86:112–120
Watzke J, Schirmer K, Scholz S (2007) Bacterial lipopolysaccharides induce genes involved in the innate immune response in embryos of the zebrafish (Danio rerio). Fish Shellfish Immun 23:901–905
Weil M, Sacher F, Scholz S, Zimmer M, Nagel R, Duis K (2008) Gene expression analysis in zebrafish embryos—a potential approach to predict long-term effects and replace chronic fish toxicity tests (in prep)
Wiegand C, Pflugmacher S, Oberemm A, Meems N, Beattie K, Steinberg C, Codd G (1999) Uptake and effects of microcystin-LR on detoxication enzymes of early life stages of the zebra fish (Danio rerio). Environ Toxicol 14:89–95
Xu J, Srinivas BP, Tay SY, Mak A, Yu X, Lee SGP, Yang H, Govindarajan KR, Leong B, Bourque G, Mathavan S, Roy S (2006) Genome-wide expression profiling in the zebrafish embryo identifies target genes regulated by hedgehog signaling during vertebrate development. Genetics 174:735–752
Yang L, Kemadjou J, Zinsmeister C, Bauer M, Legradi J, Müller F, Pankratz J, Jaeke J, Straehle U (2007) Transcriptional profiling reveals barcode-like toxicogenomic responses in the zebrafish embryo. Genome Biol 8:R227