The urinary excretion of dextromethorphan and three metabolites in dogs and humans

Toxicology and Applied Pharmacology - Tập 55 - Trang 43-48 - 1980
James W. Barnhart1
1Department of Pharmacology, The Dow Chemical Company, Post Office Box 68511, Indianapolis, Indiana 46268 USA

Tài liệu tham khảo

Barnhart, 1979, Determination of dextromethorphan in serum by gas chromatography, J. Chromatogr., 163, 390, 10.1016/S0378-4347(00)81642-4 Benson, 1953, Comparative pharmacology of levorphan, racemorphan and dextrorphan and related methyl ethers, J. Pharmacol. Exp. Ther., 109, 189 Brossi, 1955, Die papierchromatographische bestimmung von morphinanderivaten und die verfolgung ihrer ausscheidung beim hund, Arz.-Forsch., 5, 62 Calesnick, 1967, Latency of cough response as a measure of antitussive agents, Clin. Pharmacol. Ther., 8, 374, 10.1002/cpt196783374 Clark, R. L. (1956). U.S. Patent No. 2,741,617. Dixon, 1978, Dextromethorphan: radioimmunoassay and pharmacokinetics in the dog, Res. Commun. Chem. Pathol. Pharmacol., 22, 243 Eddy, 1969, Codeine and its alternates for pain and cough relief, Bull. W.H.O., 40, 639 Kamm, 1967, Metabolism and excretion of tritiated dextromethorphan by the rat, J. Pharmacol. Exp. Ther., 158, 437 Ramachander, 1977, Determination of dextrorphan in plasma and evaluation of bioavailability of dextromethorphan hydrobromide in humans, J. Pharm. Sci., 66, 1047, 10.1002/jps.2600660740 Ramachander, 1978, Effect of salicylamide and acetaminophen on dextromethorphan hydrobromide metabolism: Possible pharmacological implications, J. Pharm. Sci., 67, 761, 10.1002/jps.2600670607 Willner, 1963, Ausscheidung und abbau von (+)-3-methoxy-N-methylmorphinan und seinen entmethylierten derivaten beim menschen, Arz.-Forsch., 13, 26