The thermolabile variant of methylenetetrahydrofolate reductase (MTHFR) is not a major risk factor for neural tube defect in American Caucasians

Marcy C. Speer1, Gordon Worley2, Joanne Mackey2, Elizabeth C. Melvin1, W. Jerry Oakes3, Timothy M. George4
1Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA, , US
2Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA, , US
3Department of Surgery, University of Alabama, Birmingham, AL 35233, USA, US
4Department of Surgery and Pediatrics, Duke University Medical Center, Durham, NC 27710, USA, US

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