The systemic immunostimulatory effects of radiation therapy producing overall tumor control through the abscopal effect
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Jaffray DA (2012) Image-guided radiotherapy: from current concept to future perspectives. Nat Rev Clin Oncol 9(12):688–699
Orth M, Lauber K, Niyazi M, Friedl AA, Li M, Maihöfer C, Schüttrumpf L, Ernst A, Niemöller OM, Belka C (2014) Current concepts in clinical radiation oncology. Radiat Environ Biophys 53(1):1–29
Barton MB, Jacob S, Shafiq J, Wong K, Thompson SR, Hanna TP, Delaney GP (2014) Estimating the demand for radiotherapy from the evidence: a review of changes from 2003 to 2012. Radiother Oncol 112(1):140–144
Salama AK, Postow MA, Salama JK (2016) Irradiation and immunotherapy: from concept to the clinic. Cancer 122(11):1659–1671
Kaminski JM, Shinohara E, Summers JB, Niermann KJ, Morimoto A, Brousal J (2005) The controversial abscopal effect. Cancer Treat Rev 31(3):159–172
Jatoi I, Benson JR, Kunkler I (2018) Hypothesis: can the abscopal effect explain the impact of adjuvant radiotherapy on breast cancer mortality? NPJ Breast Cancer 4:8
Becquerel AH (1896) Sur les radiations ´emises par phosphorescence. Rend Acad Sci 122:420–421
Curie P, Curie M (1898) Sur une substance nouvelle radioactive, contenue dans la pechblende. C R Acad Sci 127:125
Schäfer W, Witte E (1932) Über eine neue Körperhöhlenröntgenröhre zur Bestrahulung von Uterustumoren. Strahlentherapie 44:283
Becquerel AH, Curie P (1901) Action physiologique des rayons de radium. C R Acad Sci 132:1289–1291
Thoraeus RA (1932) A study of ionization method for measuring the intensity and absorption of roentgen rays and of the efficiency of different filters used in therapy. Acta Radiol 18:1–86
Thariat J, Hannoun-Levi JM, Sun Myint A, Vuong T, Gerard JP (2013) Past, present, and future of radiotherapy for the benefit of patients. Nat Rev Clin Oncol 10(1):52–60
Slater JM (2012) From X-rays to ion beams: a short history of radiation therapy. In: Linz U (ed) Ion beam therapy, biological and medical physics, biomedical engineering. Springer-Verlag, Berlin, pp 3–16
Gianfaldoni S, Gianfaldoni R, Wollina U, Lotti J, Tchernev G, Lotti T (2017) An overview on radiotherapy: from its history to its current applications in dermatology. Open Access Maced J Med Sci 5(4):521–525
Vatner RE, Cooper BT, Vanpouille-Box C, Demaria S, Formenti SC (2014) Combinations of immunotherapy and radiation in cancer therapy. Front Oncol 4:325
Kamrava M, Bernstein MB, Camphausen K, Hodge JW (2009) Combining radiation, immunotherapy, and antiangiogenesis agents in the management of cancer: the Three Musketeers or just another quixotic combination? Mol BioSyst 5(11):1262–1270
Twyman-Saint Victor C, Rech AJ, Maity A, Rengan R, Pauken KE, Stelekati E, Benci JL, Xu B, Dada H, Odorizzi PM, Herati RS, Mansfield KD, Patsch D, Amaravadi RK, Schuchter LM, Ishwaran H, Mick R, Pryma DA, Xu X, Feldman MD, Gangadhar TC, Hahn SM, Wherry EJ, Vonderheide RH, Minn AJ (2015) Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer. Nature. 520(7547):373–377
Hodge JW, Guha C, Neefjes J, Gulley JL (2008) Synergizing radiation therapy and immunotherapy for curing incurable cancers. Opportunities and challenges. Oncology (Williston Park) 22(9):1064–1070 discussion 1075, 1080-1061, 1084
Bitran J (2019) The abscopal effect exists in non-small cell lung cancer: a case report and review of the literature. Cureus. 11(2):e4118
Kim JO, Kim CA (2019) Abscopal resolution of a hepatic metastasis in a patient with metastatic cholangiocarcinoma following radical stereotactic body radiotherapy to a synchronous early stage non-small cell lung cancer. Cureus. 11(2):e4082
Lin X, Lu T, Xie Z, Qin Y, Liu M, Xie X, Li S, Zhou C (2019) Extracranial abscopal effect induced by combining immunotherapy with brain radiotherapy in a patient with lung adenocarcinoma: a case report and literature review. Thorac Cancer 10(5):1272–1275
Hamilton AJ, Seid J, Verdecchia K, Chuba P (2018) Abscopal effect after radiosurgery for solitary brain metastasis from non-small cell lung cancer. Cureus. 10(12):e3777
Britschgi C, Riesterer O, Burger IA, Guckenberger M, Curioni-Fontecedro A (2018) Report of an abscopal effect induced by stereotactic body radiotherapy and nivolumab in a patient with metastatic non-small cell lung cancer. Radiat Oncol 13(1):102
Cong Y, Shen G, Wu S, Hao R (2017) Abscopal regression following SABR for non-small-cell-lung cancer: a case report. Cancer Biol Ther. 18(1):1–3
Katayama K, Tamiya A, Koba T, Fukuda S, Atagi S (2017) An abscopal response to radiation therapy in a patient with metastatic non-small cell lung cancer: a case report. J Cancer Sci Ther 9:365–367
Cummings AL, Kaprealian TB, Sarantopoulos AP, Mendenhall MA, Goldman JW An abscopal effect in a case of neuroendocrine atypical carcinoid lung cancer. Appl Radiation Oncol 2017:39–39
Komatsu T, Nakamura K, Kawase A (2017) Abscopal effect of nivolumab in a patient with primary lung cancer. J Thorac Oncol 12(9):e143–e144
Golden EB, Demaria S, Schiff PB, Chachoua A, Formenti SC (2013) An abscopal response to radiation and ipilimumab in a patient with metastatic non-small cell lung cancer. Cancer Immunol Res 1(6):365–372
Siva S, Callahan J, MacManus MP, Martin O, Hicks RJ, Ball DL (2013) Abscopal [corrected] effects after conventional and stereotactic lung irradiation of non-small-cell lung cancer. J Thorac Oncol 8(8):e71–e72
Yoon SM, Lee JS (2012) Case of abscopal effect with metastatic non-small-cell lung cancer. Oncothermia J 5:53–57
Tsui JM, Mihalcioiu C, Cury FL (2018) Abscopal effect in a stage IV melanoma patient who progressed on pembrolizumab. Cureus. 10(2):e2238
Sims-Mourtada J, Sims-Mourtada S, Casteneda S et al (2018) Dosimetric characterization of an abscopal response in a patient with oligometastatic melanoma undergoing concurrent treatment with pembrolizumab and stereotactic body radiotherapy. Cancer Stud Mol Med 4:1–4
Komori T, Otsuka A, Irie H, Horiguchi A, Honda T, Kabashima K (2018) Drastic effect on giant lung metastatic melanoma by sequential administration of nivolumab with ipilimumab/radiation combination therapy. J Dermatol 45(1):e7–e8
Sperduto W, King DM, Watanabe Y, Lou E, Sperduto PW (2017) Case report of extended survival and quality of life in a melanoma patient with multiple brain metastases and review of literature. Cureus. 9(12):e1947
Fujimura T, Kambayashi Y, Furudate S, Hidaka T, Sato Y, Tanita K, Tono H, Tsukada A, Hashimoto A, Aiba S (2017) Successful treatment of multiple in-transit melanomas on the leg with intensity-modulated radiotherapy and immune checkpoint inhibitors: report of two cases. J Dermatol 44(5):592–595
Okwan-Duodu D, Pollack BP, Lawson D, Khan MK (2015) Role of radiation therapy as immune activator in the era of modern immunotherapy for metastatic malignant melanoma. Am J Clin Oncol 38(1):119–125
Teulings HE, Tjin EP, Willemsen KJ et al (2013) Radiation-induced melanoma-associated leucoderma, systemic antimelanoma immunity and disease-free survival in a patient with advanced-stage melanoma: a case report and immunological analysis. Br J Dermatol 168(4):733–738
Stamell EF, Wolchok JD, Gnjatic S, Lee NY, Brownell I (2013) The abscopal effect associated with a systemic anti-melanoma immune response. Int J Radiat Oncol Biol Phys 85(2):293–295
Postow MA, Callahan MK, Barker CA, Yamada Y, Yuan J, Kitano S, Mu Z, Rasalan T, Adamow M, Ritter E, Sedrak C, Jungbluth AA, Chua R, Yang AS, Roman RA, Rosner S, Benson B, Allison JP, Lesokhin AM, Gnjatic S, Wolchok JD (2012) Immunologic correlates of the abscopal effect in a patient with melanoma. N Engl J Med 366(10):925–931
Hiniker SM, Chen DS, Reddy S, Chang DT, Jones JC, Mollick JA, Swetter SM, Knox SJ (2012) A systemic complete response of metastatic melanoma to local radiation and immunotherapy. Transl Oncol 5(6):404–407
Kingsley DP (1975) An interesting case of possible abscopal effect in malignant melanoma. Br J Radiol 48(574):863–866
Orton A, Wright J, Buchmann L, Randall L, Hitchcock YJ (2016) A case of complete abscopal response in high-grade pleiomorphic sarcoma treated with radiotherapy alone. Cureus. 8(10):e821
Cotter SE, Dunn GP, Collins KM, Sahni D, Zukotynski KA, Hansen JL, O’Farrell DA, Ng AK, Devlin PM, Wang LC (2011) Abscopal effect in a patient with metastatic Merkel cell carcinoma following radiation therapy: potential role of induced antitumor immunity. Arch Dermatol 147(7):870–872
Giulio F, Donato P, Beatrice D et al (2018) A case report series of renal cell carcinoma patients treated with Nivolumab and radiotherapy. J Oncol Res Ther. https://doi.org/10.29011/22574-29710X.000050
LaPlant Q, Deselm C, Lockney NA, Hsieh J, Yamada Y (2017) Potential abscopal response to dual checkpoint blockade in RCC after reirradiation using dose-painting SBRT. Pract Radiat Oncol 7(6):396–399
Ishiyama H, Teh BS, Ren H, Chiang S, Tann A, Blanco AI, Paulino AC, Amato R (2012) Spontaneous regression of thoracic metastases while progression of brain metastases after stereotactic radiosurgery and stereotactic body radiotherapy for metastatic renal cell carcinoma: abscopal effect prevented by the blood-brain barrier? Clin Genitourin Cancer 10(3):196–198
Wersall PJ, Blomgren H, Pisa P, Lax I, Kalkner KM, Svedman C (2006) Regression of non-irradiated metastases after extracranial stereotactic radiotherapy in metastatic renal cell carcinoma. Acta Oncol 45(4):493–497
MacManus MP, Harte RJ, Stranex S (1994) Spontaneous regression of metastatic renal cell carcinoma following palliative irradiation of the primary tumour. Ir J Med Sci 163(10):461–463
Fairlamb DJ (1981) Spontaneous regression of metastases of renal cancer: a report of two cases including the first recorded regression following irradiation of a dominant metastasis and review of the world literature. Cancer. 47(8):2102–2106
Lock M, Muinuddin A, Kocha WI, Dinniwell R, Rodrigues G, D’Souza D (2015) Abscopal effects: case report and emerging opportunities. Cureus. 7(10):e344
Okuma K, Yamashita H, Niibe Y, Hayakawa K, Nakagawa K (2011) Abscopal effect of radiation on lung metastases of hepatocellular carcinoma: a case report. J Med Case Rep 5:111
Nakanishi M, Chuma M, Hige S, Asaka M (2008) Abscopal effect on hepatocellular carcinoma. Am J Gastroenterol 103(5):1320–1321
Nam SW, Han JY, Kim JI et al (2005) Spontaneous regression of a large hepatocellular carcinoma with skull metastasis. J Gastroenterol Hepatol 20(3):488–492
Ohba K, Omagari K, Nakamura T, Ikuno N, Saeki S, Matsuo I, Kinoshita H, Masuda J, Hazama H, Sakamoto I, Kohno S (1998) Abscopal regression of hepatocellular carcinoma after radiotherapy for bone metastasis. Gut. 43(4):575–577
Ebner DK, Kamada T, Yamada S (2017) Abscopal effect in recurrent colorectal cancer treated with carbon-ion radiation therapy: 2 case reports. Adv Radiat Oncol 2(3):333–338
Joe MB, Lum JJ, Watson PH, Tonseth RP, McGhie JP, Truong PT (2017) Radiation generates an abscopal response and complete resolution of metastatic squamous cell carcinoma of the anal canal: a case report. J Gastrointest Oncol 8(6):E84–E89
Smith JA Jr, Herr HW (1980) Spontaneous regression of pulmonary metastases from transitional cell carcinoma. Cancer. 46(6):1499–1502
Lome LG, Navani S, Aral IM (1970) Spontaneous regression of pulmonary metastases from transitional cell carcinoma of the bladder. Cancer. 26(2):415–418
Takaya M, Niibe Y, Tsunoda S, Jobo T, Imai M, Kotani S, Unno N, Hayakawa K (2007) Abscopal effect of radiation on toruliform para-aortic lymph node metastases of advanced uterine cervical carcinoma--a case report. Anticancer Res 27(1B):499–503
Rees GJ, Ross CM (1983) Abscopal regression following radiotherapy for adenocarcinoma. Br J Radiol 56(661):63–66
Leung HW, Wang SY, Jin-Jhih H, Chan AL (2018) Abscopal effect of radiation on bone metastases of breast cancer: a case report. Cancer Biol Ther. 19(1):20–24
Azami A, Suzuki N, Azami Y, Seto I, Sato A, Takano Y, Abe T, Teranishi Y, Tachibana K, Ohtake T (2018) Abscopal effect following radiation monotherapy in breast cancer: a case report. Mol Clin Oncol 9(3):283–286
Tubin S, Casamassima F, Menichelli C, Pastore G, Fanelli M, Crisci R (2012) A case report on metastatic thyroid carcinoma: radiation-induced bystander or abscopal effect? J Cancer Sci Ther. 4:408–411
Sato H, Suzuki Y, Yoshimoto Y, Noda SE, Murata K, Takakusagi Y, Okazaki A, Sekihara T, Nakano T (2017) An abscopal effect in a case of concomitant treatment of locally and peritoneally recurrent gastric cancer using adoptive T-cell immunotherapy and radiotherapy. Clin Case Rep 5(4):380–384
Shi F, Wang X, Teng F, Kong L, Yu J (2017) Abscopal effect of metastatic pancreatic cancer after local radiotherapy and granulocyte-macrophage colony-stimulating factor therapy. Cancer Biol Ther 18(3):137–141
Lesueur P, Chevalier F, Stefan D, Habrand JL, Lerouge D, Gervais R (2017) Review of the mechanisms involved in the abscopal effect and future directions with a focus on thymic carcinoma. Tumori. 103(3):217–222
Schaub S, Stewart R, Sandison G et al (2018) Does neutron radiation therapy potentiate an immune response to Merkel cell carcinoma? Int J Particle Ther 5:183–195
Barsky AR, Cengel KA, Katz SI, Sterman DH, Simone CB (2019) First-ever abscopal effect after palliative radiotherapy and Immuno-gene therapy for malignant pleural mesothelioma. Cureus. 11(2):e4102
Desar IM, Braam PM, Kaal SE, Gerritsen WR, Oyen WJ, van der Graaf WT (2016) Abscopal effect of radiotherapy in a patient with metastatic diffuse-type giant cell tumor. Acta Oncol 55(12):1510–1512
Ehlers G, Fridman M (1973) Abscopal effect of radiation in papillary adenocarcinoma. Br J Radiol 46(543):220–222
Golden EB, Chhabra A, Chachoua A, Adams S, Donach M, Fenton-Kerimian M, Friedman K, Ponzo F, Babb JS, Goldberg J, Demaria S, Formenti SC (2015) Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trial. Lancet Oncol 16(7):795–803