The seroprevalence of neutralizing antibodies against the adeno-associated virus capsids in Japanese hemophiliacs

Molecular Therapy - Methods & Clinical Development - Tập 27 - Trang 404-414 - 2022
Yuji Kashiwakura1, Nemekhbayar Baatartsogt1, Shoji Yamazaki2, Azusa Nagao3, Kagehiro Amano4, Nobuaki Suzuki5, Tadashi Matsushita5, Akihiro Sawada6, Satoshi Higasa6, Naoya Yamasaki7, Teruhisa Fujii7, Taemi Ogura8, Hideyuki Takedani9, Masashi Taki10, Takeshi Matsumoto11, Jun Yamanouchi12, Michio Sakai13, Masako Nishikawa14, Yutaka Yatomi14, Koji Yada15
1Department of Biochemistry, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan
2Clinical Research Center, Jichi Medical University Hospital, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan
3Department of Blood Coagulation, Ogikubo Hospital, 3-1-24 Imagawa, Suginami, Tokyo 167-0035, Japan
4Department of Laboratory Medicine, Tokyo Medical University Hospital, 6-7-1, Nishishinjuku, Shinjuku, Tokyo 160-0023, Japan
5Department of Transfusion Medicine, Nagoya University Hospital, 65 Tsurumai, Showa, Nagoya, Aichi 466-8560, Japan
6Department of Respiratory Medicine and Hematology, Hyogo Medical University, 1-1 Mukogawa, Nishinomiya, Hyogo 633-8501, Japan
7Hemophilia Treatment Center, Hiroshima University Hospital, 1-2-3 Kasumi, Minami, Hiroshima, Hiroshima 734-8551, Japan
8Hemophilia Treatment Center, Shizuoka Children’s Hospital, 860 Urushiyama, Aoi, Shizuoka, Shizuoka 420-8660, Japan
9Department of Joint Surgery, IMSUT Hospital, The University of Tokyo, 4-6-1 Shirokanedai, Minato, Tokyo 108-8639, Japan
10Department of Pediatrics, St. Marianna University School of Medicine Hospital, 2-16-1 Sugao, Miyamae, Kawasaki, Kanagawa 216-8511, Japan
11Department of Transfusion Medicine and Cell Therapy, Mie University Hospital, 2-174 Edobashi, Tsu, Mie 514-8507, Japan
12Division of Blood Transfusion and Cell Therapy, Ehime University Hospital, 454 Shitsukawa, Toon, Ehime 791-0204, Japan
13Department of Pediatrics, Munakata Suikokai General Hospital, 5-7-1 Himakino, Fukutsu, Fukuoka 811-3298, Japan
14Department of Clinical Laboratory, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo, Tokyo 113-8655, Japan
15Department of Pediatrics, Nara Medical University Hospital, 840 Shijo, Kashihara, Nara 634-8522, Japan

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