The scarless heart

Morgan TH (1901) Regeneration. Macmillan, New York Stocum, 1984, The urodele limb regeneration blastema: determination and organization of the morphogenetic field, Differentiation, 27, 13, 10.1111/j.1432-0436.1984.tb01403.x Ragsdale, 1992, Delta retinoic acid receptor isoform d1 is distinguished by its exceptional N-terminal sequence and abundance in the limb regeneration blastema, Mech. Dev., 40, 99, 10.1016/0925-4773(93)90091-B Gross, 1996, Getting to mammalian wound repair and amphibian limb regeneration: a mechanistic link in the early events, Wound Repair Regen., 4, 190, 10.1046/j.1524-475X.1996.40205.x Stocum, 1996, Tissue restoration: approaches and prospects, Wound Repair Regen., 4, 3, 10.1046/j.1524-475X.1996.40104.x Clark RAF (l996) Wound repair: overview and general consideration, in The Molecular and Cellular Biology of Wound Repair (Clark RAF, ed.) pp. 3–35. Plenum Press, New York Armstrong, 1995, Ontogeny of the skin and the transition from scar-free to scarring phenotype during wound healing in the pouch of a young marsupial Monodelphis domestica, Dev. Biol., 169, 242, 10.1006/dbio.1995.1141 Hopkinson-Woolley, 1994, Macrophage recruitment during limb development and wound healing in the embryonic and fetal mouse, J. Cell Sci., 107, 1159, 10.1242/jcs.107.5.1159 Havran, 1988, Developmentally ordered appearance of thymocytes expressing different T cell receptors, Nature, 335, 443, 10.1038/335443a0 Borisov, 1999, Regeneration of skeletal and cardiac muscle in mammals: do nonprimate models resemble human pathology?, Wound Repair Regen., 7, 26, 10.1046/j.1524-475X.1999.00026.x Lutgens, 1999, Chronic myocardial infarction in the mouse: cardiac structural and functional changes, Cardiovasc. Res., 41, 586, 10.1016/S0008-6363(98)00216-8 Nakatsuji, 1996, In vivo responses of macrophages and myofibroblasts in the healing following isoproterinol-induced myocardial injury in rats, Virchows Arch., 430, 63, 10.1007/BF01008018 Jugdutt, 1996, Rate of collagen deposition during healing and ventricular remodeling after myocardial infarction in rat and dog models, Circulation, 94, 94, 10.1161/01.CIR.94.1.94 Kranz, 1975, The value of adaptation for the growth processes of the heart, ZFA, 30, 49 Lerman, 1983, Myocardial healing and repair after experimental infarction in the rabbit, Circ. Res., 53, 378, 10.1161/01.RES.53.3.378 Jugdutt, 1986, Healing after myocardial infarction in the dog: changes in infarct hydroxyproline and topography, J. Am. Coll. Cardiol., 7, 91, 10.1016/S0735-1097(86)80265-0 Mallory, 1939, The speed of healing of myocardial infarction: a study of pathologic anatomy in seventy-two cases, Am. Heart J., 18, 647, 10.1016/S0002-8703(39)90845-8 Blewett, 1997, Regenerative healing of incisional wounds in midgestational murine hearts in organ culture, J. Thorac. Cardiovasc. Surg., 113, 880, 10.1016/S0022-5223(97)70260-5 Jeter, 1971, Cell proliferation patterns during cytodifferentiation in embryonic chick tissues: liver, heart and erythrocytes, J. Embryol. Exp. Morphol., 25, 405 Goldstein, 1974, DNA synthesis and mitosis in well-differentiated mammalian cardiocytes, Science, 183, 212, 10.1126/science.183.4121.212 Mima, 1995, Fibroblast growth factor receptor is required for in vivo cardiac myocyte proliferation at early embryonic stages of heart development, Proc. Natl. Acad. Sci. U.S.A., 92, 467, 10.1073/pnas.92.2.467 Petersen, 1965, Nucleic acid and protein synthesis in cardiac muscle of growing and adult mice, Exp. Cell Res., 40, 340, 10.1016/0014-4827(65)90267-3 Anversa, 1980, Morphometric study of early postnatal development in the left and right ventricular myocardium of the rat. I. Hypertrophy, hyperplasia, and binucleation of myocytes, Circ. Res., 46, 495, 10.1161/01.RES.46.4.495 Li, 1996, Human pediatric and adult ventricular cardiomyocytes in culture: assessment of phenotypic changes with passaging, Cardiovasc. Res., 32, 362, 10.1016/0008-6363(96)00079-X Leu, 2001, Characterisation of postnatal growth of the murine heart, Anat. Embryol., 204, 217, 10.1007/s004290100206 Vracko, 1989, Connective tissue cells in healing rat myocardium: a study of cell reactions in rhymically contracting environment, Am. J. Pathol., 134, 993 Mauro, 1961, Satellite cell of skeletal muscle fibers, J. Biophys. Biochem. Cytol., 9, 493, 10.1083/jcb.9.2.493 Armand, 1983, Origin of satellite cells in avian skeletal muscles, Arch. Anat. Microsc. Morphol. Exp., 72, 163 Schultz, 1976, Fine structure of satellite cells in growing skeletal muscle, Am. J. Anat., 147, 49, 10.1002/aja.1001470105 Bischoff R (1994) The satellite cell and muscle regeneration, in Myogenesis, vol 2 (Engel AG, Franszini-Armstrong C, eds) pp. 97–118. McGraw-Hill, New York Seale, 2000, A new look at the origin, function, and stem-cell status of muscle satellite cells, Dev. Biol., 218, 115, 10.1006/dbio.1999.9565 Rumyantsev, 1976, Cumulative indices of DNA synthesizing myocytes in different compartments of the working myocardium and conductive system of the rat’s heart muscle following extensive left ventricle infarction, Virchows Arch. B Cell Pathol., 20, 329, 10.1007/BF02890352 Rumyantsev PP (1991) Replicative behavior of different types of cardiomyocytes in terms of experimental conditions, age and systematic position of animals, in The Development and Regenerative Potential of Cardiac Muscle (Oberpriller JO, Oberpriller JC, Mauro A, eds) pp 115–137. Harwood Academic Publishers, New York Butler, 1989, Evidence for a regenerative capacity in adult mammalian cardiac myocytes, Am. J. Physiol., 256, 797 Soonpaa, 1998, Survey of studies examining mammalian cardiomyocyte DNA synthesis, Circ. Res., 83, 15, 10.1161/01.RES.83.1.15 MacLellan, 2000, Genetic dissection of cardiac growth control pathways, Annu. Rev. Physiol., 62, 289, 10.1146/annurev.physiol.62.1.289 Nadal-Ginard, 1978, Commitment, fusion, and biochemical differentiation of a myogenic cell line in the absence of DNA synthesis, Cell, 15, 855, 10.1016/0092-8674(78)90270-2 Carbone, 1995, Hamster cardiomyocytes: a model of myocardial regeneration?, Ann. N.Y. Acad. Sci., 752, 65, 10.1111/j.1749-6632.1995.tb17406.x Oberpriller, 1974, Response of the adult newt ventricle to injury, J. Exp. Zool., 187, 249, 10.1002/jez.1401870208 McDonnell, 1983, The atrial proliferative response following partial ventricular amputation in the heart of the adult newt. A light and electron microscopic autoradiographic study, Tissue Cell, 15, 351, 10.1016/0040-8166(83)90068-X Nag, 1979, DNA synthesis and mitosis in adult amphibian cardiac muscle cells in vitro, Science, 205, 1281, 10.1126/science.472744 Tate, 1989, Primary cell culture and morphological characterization of ventricular myocytes from the adult newt, Notophthalmus viridescens, Anat. Rec., 224, 29, 10.1002/ar.1092240106 Soonpaa, 1994, Factors altering DNA synthesis in the cardiac myocyte of the adult newt, Notophthalmus viridescens, Cell Tissue Res., 275, 377, 10.1007/BF00319437 Oberpriller, 1995, Stimulation of proliferative events in the adult amphibian cardiac myocyte, Ann. N.Y. Acad Sci., 752, 30, 10.1111/j.1749-6632.1995.tb17404.x Neff, 1996, Heart development and regeneration in urodeles, Int. J. Dev. Biol., 40, 719 Oberpriller JO, Ferrans VJ, McDonnell TJ, Oberpriller JC (l985) Activation of DNA synthesis and mitotic events in atrial myocytes following atrial and ventricular injury, in Pathobiology of Cardiovascular Injury (Stone HL, Weglicki WB, eds) pp. 410–421. Martinus Nijhoff Publishing, Boston Beltrami, 2001, Evidence that human cardiac myocytes divide after myocardial infarction, N. Engl. J. Med., 344, 1750, 10.1056/NEJM200106073442303 Quaini, 2002, Chimerism of the transplanted heart, N. Engl. J. Med., 346, 5, 10.1056/NEJMoa012081 Anversa, 1996, Myocyte death in heart failure, Curr. Opin. Cardiol., 11, 245, 10.1097/00001573-199605000-00004 Anversa, 1998, Ventricular myocytes are not terminally differentiated in the adult mammalian heart, Circ. Res., 83, 1, 10.1161/01.RES.83.1.1 Anversa, 2000, Plasticity of the pathologic heart, Ital. Heart J., 1, 91 Warejcka, 1996, A population of cells isolated from rat heart capable of differentiating into several mesodermal phenotypes, J. Surg. Res., 62, 233, 10.1006/jsre.1996.0201 Anversa, 2002, Myocyte renewal and ventricular remodelling, Nature, 415, 240, 10.1038/415240a Fuchs, 2000, Stem cells: a new lease on life, Cell, 100, 143, 10.1016/S0092-8674(00)81691-8 Jiang, 2000, Regeneration of cardiac muscle in normal adult C57BL/6 mice, Cardiac Vasc. Regen., 1, 268 Toma, 2002, Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart, Circulation, 105, 93, 10.1161/hc0102.101442 Jackson, 2001, Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells, J. Clin. Invest., 107, 1395, 10.1172/JCI12150 Orlic, 2001, Bone marrow cells regenerate infarcted myocardium, Nature, 410, 701, 10.1038/35070587 Orlic, 2001, Mobilized bone marrow cells repair the infarcted heart, improving function and survival, Proc. Natl. Acad. Sci. U.S.A., 98, 10344, 10.1073/pnas.181177898 Laflamme, 2002, Evidence for cardiomyocyte repopulation by extracardiac progenitors in transplanted human hearts, Circ. Res., 90, 634, 10.1161/01.RES.0000014822.62629.EB Terada, 2002, Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion, Nature, 416, 542, 10.1038/nature730 Condorelli, 2001, Cardiomyocytes induce endothelial cells to trans-differentiate into cardiac muscle: implications for myocardium regeneration, Proc. Natl. Acad. Sci. U.S.A., 98, 10733, 10.1073/pnas.191217898 Hanahan, 1996, Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis, Cell, 86, 353, 10.1016/S0092-8674(00)80108-7 Risau, 1997, Mechanisms of angiogenesis, Nature, 386, 671, 10.1038/386671a0 Kim, 2001, Angiogenesis by endothelial cell transplantation, J. Thorac. Cardiovasc. Surg., 122, 963, 10.1067/mtc.2001.117623 Iannone, 2001, Effects of mixed hematopoietic chimerism in a mouse model of bone marrow transplantation for sickle cell anemia, Blood, 97, 3960, 10.1182/blood.V97.12.3960 Goss, 1970, Problems of antlerogenesis, Clin. Orthop., 69, 227 Douglas, 1972, Conservative management of guillotine amputations of the fingers of children, Aust. Paediatr. J., 8, 86 Illingworth, 1974, Trapped fingers and amputated finger tips in children, J. Pediatr. Surg., 9, 853, 10.1016/S0022-3468(74)80220-4 Goss, 1975, Epidermal downgrowths in regenerating rabbit ear holes, J. Morphol., 146, 533, 10.1002/jmor.1051460408 Borgens, 1982, Mice regrow the tips of the foretoes, Science, 217, 747, 10.1126/science.7100922 Neufield, 1989, Epidermis, basement membrane, and connective-tissue healing after amputation of mouse digits: implications for mammalian appendage regeneration, Anat. Rec., 223, 425, 10.1002/ar.1092230412 Desquenne-Clark, 1998, A new model for mammalian wound repair and regeneration, Clin. Immunol. Immunopathol., 88, 35, 10.1006/clin.1998.4519 Ferretti, 1998, Transient expression of simple epithelial keratins by mesenchymal cells of regenerating newt limb, Dev. Biol., 133, 415, 10.1016/0012-1606(89)90045-6 McBrearty, 1998, Genetic analysis of a mammalian wound healing trait, Proc. Natl. Acad. Sci. U.S.A., 95, 11792, 10.1073/pnas.95.20.11792 Masinde, 2001, Identification of wound healing/regeneration quantitative trait loci (QTL) at multiple time points that explain seventy percent of variance in (MRL/MpJ and SJL/J) mice F2 population, Genome Res., 11, 2027, 10.1101/gr.203701 Leferovich, 2001, Heart regeneration in adult MRL mice, Proc. Natl. Acad. Sci. U.S.A., 98, 9830, 10.1073/pnas.181329398 Heber-Katz, 2002, Spontaneous heart regeneration in adult MRL mice after cryo-injury, Gene Ther. Regulat., 1, 399, 10.1163/156855801760107055 Seitz, 2002, Recovery from spinal cord injury: a new transection model in the C57Bl/6 mouse, J. Neurosci. Res., 67, 337, 10.1002/jnr.10098 Chernoff, 2000, Matrix metalloproteinase production in regenerating axolotl spinal cord, Wound Repair Regen., 8, 282, 10.1046/j.1524-475x.2000.00282.x Davies, 1999, Robust regeneration of adult sensory axons in degenerating white matter of the adult rat spinal cord, J. Neurosci., 19, 5810, 10.1523/JNEUROSCI.19-14-05810.1999 Stichel, 1999, Basal membrane-depleted scar in lesioned CNS: characteristics and relationships with regenerating axons, Neuroscience, 93, 321, 10.1016/S0306-4522(99)00112-8 Condic, 2002, Extracellular matrix in spinal cord regeneration: getting beyond attraction and inhibition, Neuroreport, 13, A37, 10.1097/00001756-200203040-00002 Bradbury, 2002, Chondroitinase ABC promotes functional recovery after spinal cord injury, Nature, 416, 636, 10.1038/416636a