The role of the innate immune response in autoimmune disease

Blank, 2007, B cell targeted therapy in autoimmunity, J Autoimmun, 28, 62, 10.1016/j.jaut.2007.02.001 Abbas, 2007, Balancing autoaggressive and protective T cell responses, J Autoimmun, 28, 59, 10.1016/j.jaut.2007.02.002 Gaipl, 2007, Clearance deficiency and systemic lupus erythematosus (SLE), J Autoimmun, 28, 114, 10.1016/j.jaut.2007.02.005 Koike, 2007, Antiphospholipid antibodies: lessons from the bench, J Autoimmun, 28, 129, 10.1016/j.jaut.2007.02.009 Orban, 2007, Reduced CD4+ T-cell-specific gene expression in human type 1 diabetes mellitus, J Autoimmun, 28, 177, 10.1016/j.jaut.2007.01.002 Akira, 2006, TLR signaling, Curr Top Microbiol Immunol, 311, 1, 10.1007/3-540-32636-7_1 Hammerling, 1991, Non-deletional mechanisms of peripheral and central tolerance: studies with transgenic mice with tissue-specific expression of a foreign MHC class I antigen, Immunol Rev, 122, 47, 10.1111/j.1600-065X.1991.tb00596.x Zinkernagel, 2002, Antiinfection immunity and autoimmunity, Ann N Y Acad Sci, 958, 3, 10.1111/j.1749-6632.2002.tb02942.x Blander, 2006, Toll-dependent selection of microbial antigens for presentation by dendritic cells, Nature, 440, 808, 10.1038/nature04596 Ohashi, 1991, Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice, Cell, 65, 305, 10.1016/0092-8674(91)90164-T Limmer, 2005, Stimulation of autoimmunity by toll-like receptor ligands, Ann Rheum Dis, 64, 15 Zelenay, 2007, Physiopathology of natural auto-antibodies: The case for regulation, J Autoimmun, 29, 229, 10.1016/j.jaut.2007.07.011 Vollmers, 2007, Natural antibodies and cancer, J Autoimmun, 29, 295, 10.1016/j.jaut.2007.07.013 Ryan, 2007, Death, adaptation and regulation: the three pillars of immune tolerance restrict the risk of autoimmune disease caused by molecular mimicry, J Autoimmun, 29, 262, 10.1016/j.jaut.2007.07.014 Rowley, 2007, Autoreactive B-1 B cells: Constraints on natural autoantibody B cell antigen receptors, J Autoimmun, 29, 236, 10.1016/j.jaut.2007.07.020 Peng, 2007, Innate and adaptive immune response to apoptotic cells, J Autoimmun, 29, 303, 10.1016/j.jaut.2007.07.017 Pasquali, 2007, Auto-reactive B cells in transgenic mice, J Autoimmun, 29, 250, 10.1016/j.jaut.2007.07.006 Papadimitraki, 2007, Toll like receptors and autoimmunity: A critical appraisal, J Autoimmun, 29, 310, 10.1016/j.jaut.2007.09.001 Milner, 2007, Repertoire-dependent immunopathology, J Autoimmun, 29, 257, 10.1016/j.jaut.2007.07.019 Lutz, 2007, Homeostatic roles of naturally occurring antibodies. An overview, J Autoimmun, 29, 287, 10.1016/j.jaut.2007.07.007 Lan, 2007, Regulatory T cells in the prevention of mucosal inflammatory diseases: Patrolling the border, J Autoimmun, 29, 272, 10.1016/j.jaut.2007.07.021 Cohen, 2007, Biomarkers, self-antigens and the immunological homunculus, J Autoimmun, 29, 246, 10.1016/j.jaut.2007.07.016 Avrameas, 2007, Naturally occuring B-cell autoreactivity: a critical overview, J. Autoimmun, 29, 213, 10.1016/j.jaut.2007.07.010 Ruiz-Argüelles, 2007, Apoptosis of melanocytes in vitiligo results from antibody penetration, J Autoimmun, 29, 281, 10.1016/j.jaut.2007.07.012 Zhou, 2007, Properties and function of polyreactive antibodies and polyreactive antigen-binding B cells, J Autoimmun, 29, 219, 10.1016/j.jaut.2007.07.015 Limmer, 1998, A two-step model for the induction of organ-specific autoimmunity, Novartis Found Symp, 215, 159 Anderson, 2002, Projection of an immunological self shadow within the thymus by the aire protein, Science, 298, 1395, 10.1126/science.1075958 Frigerio, 2002, Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis, Nat Med, 8, 1414, 10.1038/nm1202-792 Horwitz, 2003, Coxsackievirus-mediated hyperglycemia is enhanced by reinfection and this occurs independent of T cells, Virology, 314, 510, 10.1016/S0042-6822(03)00462-8 Picarella, 1992, Insulitis in transgenic mice expressing tumor necrosis factor beta (lymphotoxin) in the pancreas, Proc Natl Acad Sci U S A, 89, 10036, 10.1073/pnas.89.21.10036 Lang, 2005, Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease, Nat Med, 11, 138, 10.1038/nm1176 Hamilton-Williams, 2005, Cutting edge: TLR ligands are not sufficient to break cross-tolerance to self-antigens, J Immunol, 174, 1159, 10.4049/jimmunol.174.3.1159 Ewel, 1992, C accelerates development of diabetes mellitus in diabetes-prone BB rat, Diabetes, 41, 1016, 10.2337/diabetes.41.8.1016 Sobel, 1998, Low dose poly I:C prevents diabetes in the diabetes prone BB rat, J Autoimmun, 11, 343, 10.1006/jaut.1998.0203 Alba, 2004, IFN beta accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to beta cells in nondiabetes-prone mice, J Immunol, 173, 6667, 10.4049/jimmunol.173.11.6667 Betterle, 2000, Autoimmunity against pancreatic islets and other tissues before and after interferon-alpha therapy in patients with hepatitis C virus chronic infection, Diabetes Care, 23, 1177, 10.2337/diacare.23.8.1177 Devendra, 2005, Interferon-alpha as a mediator of polyinosinic:polycytidylic acid-induced type 1 diabetes, Diabetes, 54, 2549, 10.2337/diabetes.54.9.2549 Foulis, 1987, Immunoreactive alpha-interferon in insulin-secreting beta cells in type 1 diabetes mellitus, Lancet, 2, 1423, 10.1016/S0140-6736(87)91128-7 Flodstrom, 2002, Target cell defense prevents the development of diabetes after viral infection, Nat Immunol, 3, 373, 10.1038/ni771 Horwitz, 1998, Diabetes induced by Coxsackie virus: initiation by bystander damage and not molecular mimicry, Nat Med, 4, 781, 10.1038/nm0798-781 Peng, 2004, TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes, Proc Natl Acad Sci U S A, 101, 4572, 10.1073/pnas.0400810101 Lang, 2006, Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling, J Clin Invest, 116, 2456, 10.1172/JCI28349 Voehringer, 2000, Break of T cell ignorance to a viral antigen in the liver induces hepatitis, J Immunol, 165, 2415, 10.4049/jimmunol.165.5.2415 Iwai, 2003, PD-1 inhibits antiviral immunity at the effector phase in the liver, J Exp Med, 198, 39, 10.1084/jem.20022235 Goverman, 1993, Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity, Cell, 72, 551, 10.1016/0092-8674(93)90074-Z Benveniste, 1997, Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis, J Mol Med, 75, 165, 10.1007/s001090050101 Sibley, 1985, Clinical viral infections and multiple sclerosis, Lancet, 1, 1313, 10.1016/S0140-6736(85)92801-6 Christen, 2004, Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10HSP!gradient, J Clin Invest, 113, 74, 10.1172/JCI17005 Clerico, 2007, Interferon-beta1a for the treatment of multiple sclerosis, Expert Opin Biol Ther, 7, 535, 10.1517/14712598.7.4.535 Rice, 2005, Anti-alpha4 integrin therapy for multiple sclerosis: mechanisms and rationale, Neurology, 64, 1336, 10.1212/01.WNL.0000158329.30470.D0 Langer-Gould, 2005, Progressive multifocal leukoencephalopathy in a patient treated with natalizumab, N Engl J Med, 353, 375, 10.1056/NEJMoa051847 Kurtzke, 1993, Epidemiologic evidence for multiple sclerosis as an infection, Clin Microbiol Rev, 6, 382, 10.1128/CMR.6.4.382 Nestle, 2005, Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production, J Exp Med, 202, 135, 10.1084/jem.20050500 Sano, 2005, Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model, Nat Med, 11, 43, 10.1038/nm1162 Preble, 1982, Systemic lupus erythematosus: presence in human serum of an unusual acid-labile leukocyte interferon, Science, 216, 429, 10.1126/science.6176024 Marshak-Rothstein, 2006, Toll-like receptors in systemic autoimmune disease, Nat Rev Immunol, 6, 823, 10.1038/nri1957 Bennett, 2003, Interferon and granulopoiesis signatures in systemic lupus erythematosus blood, J Exp Med, 197, 711, 10.1084/jem.20021553 Lipsky, 2001, Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity, Nat Immunol, 2, 764, 10.1038/ni0901-764 Gota, 2003, Induction of clinical autoimmune disease by therapeutic interferon-alpha, Autoimmunity, 36, 511, 10.1080/08916930310001605873 Santiago-Raber, 2003, Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice, J Exp Med, 197, 777, 10.1084/jem.20021996 Wakeland, 2001, Delineating the genetic basis of systemic lupus erythematosus, Immunity, 15, 397, 10.1016/S1074-7613(01)00201-1 Christensen, 2006, Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus, Immunity, 25, 417, 10.1016/j.immuni.2006.07.013 Ghiringhelli, 2006, The role of regulatory T cells in the control of natural killer cells: relevance during tumor progression, Immunol Rev, 214, 229, 10.1111/j.1600-065X.2006.00445.x Moins-Teisserenc, 1999, Association of a syndrome resembling Wegener's granulomatosis with low surface expression of HLA class-I molecules, Lancet, 354, 1598, 10.1016/S0140-6736(99)04206-3 Zandman-Goddard, 2002, HIV and autoimmunity, Autoimmun Rev, 1, 329, 10.1016/S1568-9972(02)00086-1 Brenchley, 2006, Microbial translocation is a cause of systemic immune activation in chronic HIV infection, Nat Med, 12, 1365, 10.1038/nm1511 Heikenwalder, 2004, Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration, Nat Med, 10, 187, 10.1038/nm987 Pateron, 1992, Latent autoimmune thyroid disease in patients with chronic HCV hepatitis, J Hepatol, 16, 244, 10.1016/S0168-8278(05)80124-2 Hadziyannis, 1996, Nonhepatic manifestations and combined diseases in HCV infection, Dig Dis Sci, 41, 63S, 10.1007/BF02087878