The role of serotonin in the pathophysiology and treatment of schizophrenia

Journal of Neuropsychiatry and Clinical Neurosciences - Tập 9 Số 1 - Trang 1-17 - 1997
Anissa Abi‐Dargham1, Marc Laruelle, G K Aghajanian, D S Charney, John H. Krystal
1Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut USA

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10.1002/9780470718896.ch6

Wooley DW, Shaw E: A biological and pharmacological suggestion about certain mental disorders. Proc NatI Acad Sci USA 1954

10.1001/archpsyc.1972.01750260021004

10.1001/archpsyc.1988.01800330013001

10.1093/schbul/17.2.263

10.1111/j.1600-0447.1990.tb05280.x

10.1176/ajp.151.6.825

10.1097/00004714-199302000-00004

Dahlstr A, 1964, Acta Physiol Scand, 62, 1

10.1002/cne.901790311

10.1016/0306-4522(81)90146-9

10.1002/cne.901640203

10.1016/0006-8993(76)91023-4

10.1016/0006-8993(87)91588-5

10.1016/0006-8993(76)90005-6

10.1016/0006-8993(78)91077-6

10.1016/0306-4522(77)90120-8

10.1002/cne.901870108

10.1016/0028-3908(86)90207-8

Hoyer D, 1994, Pharmacol Rev, 46, 157

10.1016/0028-3908(94)90058-2

10.1002/cne.903510304

10.1016/0006-8993(86)90902-9

10.1111/j.1476-5381.1957.tb00142.x

10.1016/0006-8993(86)90903-0

10.1038/330746a0

10.1111/j.1471-4159.1993.tb03208.x

Shen Y, 1993, Biol Chem, 268, 18200, 10.1016/S0021-9258(17)46830-X

Roth BL, 1994, J Pharmacol Exp Ther, 268, 1403

Monsma FJ Jr, 1993, Mol Pharmacol, 43, 320

10.1176/ajp.111.12.881

10.1111/j.1749-6632.1962.tb50103.x

10.1037/h0034952

10.1177/002076406300900401

10.1097/00005053-196808000-00008

10.1093/schbul/9.1.73

10.3928/0048-5713-19940301-09

10.1016/0024-3205(84)90436-3

10.1007/BF00176847

Stahl SM, 1987, Handbook of Schizophrenia, vol 2: Neurochemistry and Neuropharmacology of Schizophrenia, 257

10.1093/schbul/14.2.297

10.1016/S0140-6736(66)92028-9

10.1016/0028-3908(69)90046-X

10.1192/bjp.137.4.346

10.1111/j.1600-0447.1977.tb00229.x

10.1192/bjp.115.518.95

10.1016/0022-3999(71)90051-1

10.1001/archpsyc.1975.01760260127011

10.1001/archpsyc.1974.01760130034005

10.1016/0165-1781(83)90003-3

10.1176/ajp.140.1.21

Losonczy MF, Song IS, Mohs RC, etal: Correlates of lateral ventricular size in chronic schizophrenia, II: biological measures. Am .1 Psychiatry 1986; 143:1113-1118

10.1016/0165-1781(85)90001-0

10.1111/j.1749-6632.1986.tb27898.x

10.1001/archpsyc.1988.01800310013001

10.1111/j.1749-6632.1988.tb42115.x

10.1001/archpsyc.1993.01820200009001

10.1111/j.1600-0447.1979.tb00261.x

10.1007/BF00431959

10.1192/bjp.134.3.249

Farley IJ, 1980, Enna SJ, 427

10.1007/BF01276538

10.1001/archpsyc.1993.01820220066007

10.1038/npp.1993.32

10.1046/j.1471-4159.1995.64031197.x

Peroutka SJ, 1979, Mol Pharmacol, 16, 687

10.1001/archpsyc.1979.01780090013001

10.1001/archpsyc.1981.01780280046004

Leysen JE, 1990, Neuropsychopharmacology, 3, 361

Choudhary MS., 1992, Mol Pharmacol, 42, 627

10.1016/0006-3223(86)90332-X

10.1007/BF01244654

Reynolds CP, 1983, J Neural Transm, 18, 273

10.1016/0024-3205(83)90162-5

10.1111/j.1471-4159.1986.tb12944.x

10.3109/10799898709054987

10.1038/272168a0

Leysen JE, Van Nueten JM, et al: [3H]Ketanserin (R 41 468), a selective H-ligand for serotonin-2 receptor binding sites: binding properties, brain distribution and functional role. Mo! Pharmacol 1982

10.1016/0014-2999(87)90544-9

10.1001/archpsyc.1990.01810230054009

10.1176/ajp.146.6.730

10.1016/0006-8993(93)91015-K

10.1001/archpsyc.1986.01800100048007

10.1016/S0140-6736(83)92590-4

10.1016/0006-8993(88)91621-6

10.1016/0006-8993(86)91415-0

10.1016/0006-8993(94)90932-6

10.1016/0006-8993(90)90274-F

10.1016/S0140-6736(83)91310-7

10.1016/0024-3205(91)90556-Q

10.1016/0006-8993(93)90191-O

10.3109/10799898809048978

10.1016/0006-3223(89)90217-5

10.1016/0006-3223(91)90184-N

Conn PJ, 1987, J Pharmacol Exp Ther, 242, 552

10.1016/0197-0186(91)90117-V

10.1016/0165-1781(91)90013-F

10.1016/0006-3223(91)90233-C

10.1001/archpsyc.1993.01820200034004

10.1016/0165-1781(92)90136-Q

10.1016/0006-3223(93)90241-5

10.1001/archpsyc.1993.01820200046005

10.1007/BF00216006

Wurtman RJ, 1981, Pharmacol Rev, 32, 315

10.1001/archneurpsyc.1958.02340070140021

10.1126/science.133.3446.104

10.1016/0028-3908(70)90011-0

Cil J, Wyatt R: Clinical effects of tryptophan in chronic schizophrenic patients. Bio! Psychiatry 1976

Chouinard G, et a!: A controlled study of tryptophan-benserazide in schizophreni Communications in Psychopharmacology 1978

Morand C, 1983, Biol Psychiatry, 18, 575

10.1126/science.177.4054.1124

Bige L, Clinical effects of L-5-hydroxytryptophan administration in chronic schizophrenic patients. Bio! Psychiatry 1979

10.1016/0006-3223(87)90134-X

Casacchia M, 1975, Biol Psychiatry, 10, 109

DeLisi L, 1982, Biol Psychiatry, 11, 471

10.1016/0006-3223(85)90068-X

10.1016/0006-3223(85)90008-3

Soper HV, 1990, J Clin Psychopharmacol, 10, 168, 10.1097/00004714-199006000-00003

10.1126/science.1145194

10.1126/science.3854

10.1176/ajp.137.12.1518

Baldessarini RJ, Frankenburg FR: Clozapine: a novel antipsychotic agent. N EngI J Med 1991

10.1016/0920-9964(91)90030-U

10.1192/S0007125000292544

Seeman P, 1992, Neuropsychopharmacology, 7, 261

10.1016/0014-2999(90)94100-C

Deutch AY, Regionally specific effects of atypical antipsychotic drugs on striata! fos expression: the nucleus accumbens shell as a locus of antipsychotic action. Mo! Cell Neurosci 1992

10.1016/0361-9230(86)90181-4

10.1038/350610a0

Rasmussen K, Aghajanian CK: Potency of antipsychotics in reversing the effects of a hallucinogenic drug on locus coeruleus neurons correlates with 5-HT2 binding affinity. Neuropsychopharmaco! 1988

Me H, 1989, Psychopharmacology, 99, S18, 10.1007/BF00442554

Meltzer H, D-2, and serotomn 2 pki values. J Pharmaco! Exp Ther 1989

Meco C, 1989, Current Therapy Research, 46, 876

10.1007/BF00589890

10.1111/j.1600-0447.1992.tb01473.x

10.1111/j.1600-0447.1993.tb03480.x

10.1192/S0007125000295950

Bersani C, Crispini A, Marii S, eta!: 5-HT2 antagonist ritanserin in neuroleptic induced parkinsonism: a double blind comparison with orphenadrine and placebo. Clin Neuropharmaco! 1990; 13:500-506

Miller CH, et a!: Treatment of neuroleptic induced akathisia with the 5-HT2 antagonist ritanserin. Psychopharmaco! Bull 1990

Bleekers E, 1990, Collegium Internationale Neuro-psychopharmacologicum (CINP)

10.1007/BF02245441

Sorensen SM, eta!: Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies. J Pharmaco! Exp Ther 1993

Rossum V, The significance of dopamine receptor blockade for the mechanism of action of neuroleptic drugs. Arch mt Pharmacodyn Ther 1966

Car A, 1963, Acta Pharmacol Toxicol, 20, 140, 10.1111/j.1600-0773.1963.tb01730.x

10.1176/ajp.130.1.61

10.1016/S0166-2236(84)80062-4

Hornykiewicz 0, 1986, The Neurobiology of Dopamine Systems

10.1001/archpsyc.1973.04200020023003

10.1001/archpsyc.1987.01800190080012

10.1176/ajp.148.11.1474

10.1016/0306-4522(91)90196-U

10.1016/0014-2999(68)90021-6

10.1016/0028-3908(71)90005-0

10.1016/0006-8993(74)90433-8

10.1016/0006-8993(75)90060-8

10.1016/0006-8993(76)91024-6

10.1016/0006-8993(73)90429-0

10.1016/0006-8993(75)90233-4

10.1016/0031-9384(72)90026-1

10.1016/0028-3908(79)90122-9

10.1016/0014-2999(74)90019-3

Green TK, Harvey JA: Enhancement of amphetamine action after interruption of ascending serotonergic pathways. J Pharmaco! Exp Ther 1974

10.1016/0006-8993(76)90904-5

10.1111/j.1476-5381.1974.tb09714.x

Hollister A, 1976, J Pharmacol Exp Ther, 198, 12

10.1016/0028-3908(75)90054-4

Neuburg J, 1974, Biol Psychiatry, 8, 139

Crabowska ML, 1973, Polish Journal of Pharmacology and Pharmacy, 25, 29

10.1016/0006-8993(75)90295-4

10.1111/j.2042-7158.1976.tb02783.x

10.1016/0014-2999(81)90556-2

10.1016/0014-2999(69)90202-7

10.1016/0006-8993(69)90122-X

Ernst AM, 1972, Archives Internationales de Pharmacodynamie, 199, 219

10.1016/0014-2999(72)90230-0

10.1016/0306-4522(80)90048-2

10.1111/j.2042-7158.1976.tb04140.x

10.1016/0006-8993(78)91110-1

10.1111/j.2042-7158.1980.tb12889.x

10.1016/0014-2999(79)90492-8

10.1111/j.2042-7158.1978.tb13188.x

10.1016/0014-2999(81)90038-8

Blackburn TP, 1979, Br J Pharmacol, 67, 431

10.1016/0006-8993(75)90060-8

10.1016/0024-3205(79)90396-5

10.1016/0006-8993(87)90683-4

Fog R, 1972, Acta Neurol Scand, 48, 3

10.1016/0006-8993(72)90208-9

10.1016/0028-3908(75)90114-8

Carter CJ, 1977, Br J Pharmacol, 60, 267P

10.1016/0014-2999(79)90110-9

10.1007/BF00495549

10.1016/0024-3205(90)90365-X

10.1111/j.2042-7158.1983.tb02880.x

10.1038/333174a0

10.1007/BF00442004

10.1016/0014-2999(91)90235-I

Coldstein JM, 1989, J Pharmacol Exp Ther, 249, 673

10.1016/0014-2999(94)00698-7

10.1016/0014-2999(93)90555-V

Pehek EA, 1993, Society for Neuroscience Abstracts, 19, 302

10.1111/j.1471-4159.1990.tb01230.x

10.1097/00004714-199502001-00003

10.1111/j.1748-1716.1989.tb08640.x

10.1176/ajp.135.9.1081

10.1038/285355a0

Svensson TH, 1993, Schizophr Res, 11, 115P

10.1111/j.1748-1716.1989.tb08694.x

Crenhoffj CS, 1990, Pharmacol Toxicol, 29

10.1016/0166-4328(86)90032-X

10.1016/0024-3205(90)90484-9

10.1046/j.1471-4159.1994.62041382.x

10.1126/science.1257777

10.1016/0165-0173(81)90004-7

10.1111/j.1471-4159.1988.tb02919.x

10.1016/0014-2999(93)90859-G

10.1016/0006-8993(95)00865-N

10.1097/00004850-199311002-00004

Laruelle M, Proc NatI Acad Sd USA 1996; 93:9235-9240

10.1002/syn.890090307

10.1016/0006-8993(93)90402-9

10.1016/0014-2999(94)90502-9

10.1038/sj.npp.1380102

10.1001/archpsyc.1991.01810350036005

Selemon LD, 1993, Society for Neuroscience Abstracts, 19, 200

10.1016/0006-3223(93)90065-L

10.1001/archpsyc.1995.03950160008002

Arnold SE, Abnormal expression of two microtubule associated proteins (MAP2 and MAP5) in specific subfields of the hippocampal formation in schizophrenia. Proc NatI Acad Sci USA 1991

10.1016/0893-133X(94)00081-A

10.1007/BF00428897

10.1016/0163-1047(91)80140-A

Roth BL, Hamblin M

10.1016/0024-3205(86)90060-3

10.1016/0361-9230(89)90198-6

10.1016/0165-0173(93)90008-N

10.1136/bmj.280.6207.66

10.1007/BF00433802

10.1126/science.347574

10.1007/BF01245228

10.1176/ajp.153.4.466

Laruelle M, Abi-Dargham A, van Dyck CH, etal: SPECT imaging of striatal dopamine release after amphetamine challenge. J NucI Med 1995; 36:1182-1190