The role of radiotherapy in 74 patients with dermatofibrosarcoma protuberans
Tóm tắt
To study treatment and prognostic factor in 74 patients with dermatofibrosarcoma protuberans. From August 1990 to November 1999, 74 patients with dermatofibrosarcoma protuberans (DFSP) confirmed by pathology were treated in Cancer Hospital of Sun Yat-sen University. 72 cases were given wide excision and 2 cases were given local excision. All of 74 cases, 52 cases had surgical resection alone, and 22 cases had surgical resection combined with radiotherapy. Total dose of radiotherapy was 50–70 Gy. The rate of recurrence was 36.1% for all patients. The 5-year recurrence-free survival (RFS) rate was 66%. The 5-year recurrence-free survival rates for resection alone and combined with radiotherapy were 58% and 90%, respectively (P=0.0187). The 5-year recurrence-free survival rates for positive microscopic margins and negative microscopic margins were 57% and 75%, respectively (P=0.0468). Post-operation radiotherapy is an effective treatment to decrease the recurrence rate for the patients with positive microscope, or the patients without suitable surgical treatment.
Tài liệu tham khảo
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