The role of nucleotides in human nutrition
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Uauy, 1989, Dietary nucleotides and requirements in early life, 265
Rudolph, 1994, The biochemistry and physiology of nucleotides, J. Nutr., 124, 124S, 10.1093/jn/124.suppl_1.124S
Chu, 1991, Nucleotides: biochemistry and metabolism, Sem. Pediatr. Gastr. Nutr., 2, 6
Quan, 1991, Nucleotides and gastrointestinal development, Sem. Pediatr. Gastr. Nutr., 2, 3
Cory, 1992, Purine and pyrimidine nucleotide metabolism, 529
Martin, 1989, Metabolism of purine and pyrimidine nucleotides, 357
Dubyak, 1993, Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides, Cell Physiol., 34, C577, 10.1152/ajpcell.1993.265.3.C577
Gordon, 1986, Extracellular ATP: effects, sources and fate, Biochem. J., 233, 309, 10.1042/bj2330309
Donovan, 1989, Non-protein nitrogen and true protein in infant formulas, Acta Paediatr. Scand., 78, 497, 10.1111/j.1651-2227.1989.tb17927.x
Carlson, 1985, Human milk nonprotein nitrogen: occurrence and possible functions, Adv. Pediatr., 32, 43
Janas, 1982, The nucleotide profile of human milk, Pediatr. Res., 16, 659, 10.1203/00006450-198208000-00014
Gil, 1981, Acid-soluble nucleotides of cow's, goat's and sheep's milks, at different stages of lactation, J. Diary Res., 48, 35, 10.1017/S0022029900021427
Gil, 1982, Acid-soluble nucleotides of human milk at different stages of lactation, J. Dairy Res., 49, 301, 10.1017/S0022029900022391
Deutsch, 1960, The acid soluble nucleotides of human milk, Z. Physiol. Chem., 321, 246, 10.1515/bchm2.1960.321.1.246
Kobata, 1962, The acid-soluble nucleotides of milk, J. Biochem., 51, 277, 10.1093/oxfordjournals.jbchem.a127533
Johke, 1963, Acid-soluble nucleotides of colostrum, milk, and mammary gland, J. Biochem., 54, 388, 10.1093/oxfordjournals.jbchem.a127804
Kojima, 1974, Safety evaluation of disodium 5′-inosinate, disodium 5′-guanylate and disodium 5′-ribonucleate, Toxicology, 2, 185, 10.1016/0300-483X(74)90009-2
Sanchez-Pozo, 1994, Dietary nucleotides influence lipoprotein metabolism in newborn infants, Pediatr. Res., 35, 112, 10.1203/00006450-199401000-00023
Quinty, 1992, Nucleotide monophosphate levels in human milk, FASEB J., 6, A1115
Von Euler, 1963, Fatty livers induced by orotic acid, J. Biol. Chem., 238, 2464, 10.1016/S0021-9258(19)67994-9
Harden, 1984, Hypocholesteremia induced by orotic acid: dietary effects and species specificity, J. Nutr., 114, 411, 10.1093/jn/114.2.411
Durschlag, 1980, Species specificity in the metabolic consequences of orotic acid consumption, J. Nutr., 110, 822, 10.1093/jn/110.4.822
Goldman, 1989, Immunologic system in human milk: characteristics and effects, 135
Sanguansermsri, 1974, Polyamines in human and cow's milk, Am. J. Clin. Nutr., 2, 859, 10.1093/ajcn/27.8.859
Waslien, 1968, Uric acid production of men fed graded amounts of egg protein and yeast nucleic acid, Am. J. Clin. Nutr., 21, 892, 10.1093/ajcn/21.9.892
Seegmiller, 1977, Immunological aspects of purine metabolism, Adv. Exp. Med. Biol., 76A, 412
Edozien, 1970, Effects of high levels of yeast feeding on uric acid metabolism of young men, Nature, 228, 180, 10.1038/228180a0
Griebsch, 1974, Effect of ribomononucleotides given orally in uric acid production in man, Adv. Exp. Med. Biol., 41B, 443, 10.1007/978-1-4757-1433-3_9
Clifford, 1976, Effect of oral purines on serum and urinary uric acid of normal, hyperuricemic and gouty humans, J. Nutr., 106, 428, 10.1093/jn/106.3.428
Faelli, 1970, Effect of inosine and its metabolites on intestinal iron absorption in the rat, Biochem. Pharmacol., 19, 2551, 10.1016/0006-2952(70)90003-1
Owen, 1960, Xanthine oxidase in human milk, 19, 28
Zikakis, 1976, The presence and some properties of xanthine oxidase in human milk and colostrum, J. Food Sci., 41, 1408, 10.1111/j.1365-2621.1976.tb01183.x
Topham, 1981, Purification and characterization of the intestinal promoter of iron(3+) transferrin formation, Biochem., 20, 319, 10.1021/bi00505a014
Topham, 1978, Isolation of an intestinal promotor of Fe3+-transferrin formation, Biochem. Biophys. Res. Commun., 85, 1339, 10.1016/0006-291X(78)91150-6
McMillan, 1977, Iron absorption from human milk, simulated human milk, and proprietary formulas, Pediatrics, 60, 896, 10.1542/peds.60.6.896
Nagai, 1963, The effect of supplementation of nucleotides to commercial milk on the weight gain of premature and healthy infants, Ann. Paed. Jap., 9, 40
Kobota, 1969, Nutritional study of nucleotide components in the milk, Acta Paediatr. Jap., 73, 197
Gil, 1985, Effect of dietary nucleotides on the plasma fatty acids in at-term neonates, Hum. Nutr: Clin. Nutr., 40C, 185
Gil, 1986, Effects of the addition of nucleotides to an adapted milk formula on the microbial pattern of faeces in at-term newborn infants, J. Clin. Nutr. Gastroenterol., 1, 127
Sanchez-Pozo, 1986, Effects of dietary nucleotides upon lipoprotein pattern of newborn infants, Nutr. Res., 6, 763, 10.1016/S0271-5317(86)80159-2
DeLucchi, 1987, Effects of dietary nucleotides on the fatty acid composition of erythrocyte membrane lipids in term infants, J. Ped. Gastroenterol. Nutr., 6, 568, 10.1097/00005176-198707000-00014
Villarroel, 1987, Nucleotides addition to a milk adapted formula: effect on serum lipoproteins cholesterol levels in the newborn (Spanish), Rev. Chil. Nutr., 15, 179
Gil, 1988, Changes in the fatty acid profiles of plasma lipid fractions induced by dietary nucleotides in infants born at term, Eur. J. Clin. Nutr., 42, 473
Pita, 1988, Changes in the fatty acid patterns of red blood cell phospholipids induced by type of milk, dietary nucleotide supplementation, and postnatal age in preterm infants, Pediatr. Gastroenterol. Nutr., 7, 740, 10.1097/00005176-198809000-00020
Carver, 1991, Dietary nucleotide effects upon immune function in infants, Pediatrics, 88, 359, 10.1542/peds.88.2.359
DeCastor, 1992, The effects of Super Preemie SMA with nucleotides on the hematology and blood chemistry of very low birthweight infants, Pediatr. Res., 287A
DeCastor, 1992, The effects of Super Preemie SMA with nucleotides on the growth and development of very low birthweight infants, Pediatr. Res., 287A
Brunser, 1994, Effect of dietary nucleotide supplementation on diarrhoeal disease in infants, Acta Paediatr., 883, 188, 10.1111/j.1651-2227.1994.tb13048.x
Clifford, 1976, Levels of purines in foods and their metabolic effects in rats, J. Nutr., 106, 435, 10.1093/jn/106.3.435
Kuninaka, 1966, Recent studies of 5′-nucleotides as new flavor enhancers, 261
Yamaguchi, 1967, The synergistic taste effect of monosodium glutamate and disodium 5′ inosinate, J. Food Sci., 32, 472, 10.1111/j.1365-2621.1967.tb09715.x
Fuke, 1991, Taste active components in some foods: a review of Japanese research, Physiol. Behav., 49, 863, 10.1016/0031-9384(91)90195-T
Novak, 1994, Dietary nucleotides affect hepatic growth and composition in the weanling mouse, J. Parenter. Enter. Nutr., 18, 62, 10.1177/014860719401800162
Simmonds, 1973, Metabolic studies of purine metabolism in the pig during the oral administration of guanine and allopurinol, Biochem. Pharmacol., 22, 2537, 10.1016/0006-2952(73)90062-2
Sonoda, 1978, Metabolic rate of pyrimidines and purines in dietary nucleic acids ingested by mice, Biochim. Biophys. Acta, 521, 55, 10.1016/0005-2787(78)90248-4
Bowering, 1969, Dietary protein level and uric acid metabolism in normal man, J. Nutr., 100, 249, 10.1093/jn/100.2.249
Kolassa, 1977, Adenosine uptake by the isolated epithelium of guinea pig jejunum, Can. J. Physiol. Pharmacol., 55, 1033, 10.1139/y77-142
Ho, 1979, Absorption and metabolism of orally administered purines in fed and fasted fats, J. Nutr., 109, 1377, 10.1093/jn/109.8.1377
Salati, 1984, Absorption and metabolism of adenine, adenosine-5′-mono-phosphate, adenosine and hypoxanthine by the isolated vascularly perfused rat small intestine, J. Nutr., 114, 753, 10.1093/jn/114.4.753
Schwenk, 1984, Uridine uptake by isolated intestinal epithelial cells of guinea pig, Biochimica et Biophysica Acta, 805, 370, 10.1016/0167-4889(84)90020-X
Jakobs, 1986, Sodium-dependent, concentrative nucleoside transport in cultured intestinal epithelial cells, Biochem. Biophys. Res. Commun., 140, 1028, 10.1016/0006-291X(86)90738-2
Bronk, 1987, Absorption of 5-fluorouracil and related pyrimidines in rat small intestine, Clin. Science, 72, 705, 10.1042/cs0720705
Bronk, 1987, The transport of pyrimidines into tissue rings cut from rat small intestine, J. Physiol., 382, 475, 10.1113/jphysiol.1987.sp016379
Jarvis, 1989, Characterization of sodium-dependent nucleoside transport in rabbit intestinal brush-border membrane vesicles, Biochim. Biophys. Acta, 979, 132, 10.1016/0005-2736(89)90533-6
Parsons, 1983, Use of high performance liquid chromatography to study absorption and metabolism of purines by rat jejunum in vitro, Quart. J. Exp. Physiol., 68, 53, 10.1113/expphysiol.1983.sp002702
Imondi, 1969, Changes in enzyme levels accompanying differentiation of intestinal epithelial cells, Exp. Cell Res., 58, 323, 10.1016/0014-4827(69)90512-6
Sorensen, 1960, The elimination of uric acid in man, Scand. J. Clin. Lab. Invest., 12, 1
Berlin, 1968, Secretions of purines by the small intestine: general characteristics, Am. J. Physiol., 215, 932, 10.1152/ajplegacy.1968.215.4.932
Mohamedali, 1993, The highest levels of purine catabolic enzymes in mice are present in the proximal small intestine, J. Biol. Chem., 5, 23728, 10.1016/S0021-9258(19)49521-5
Chinsky, 1990, Developmental expression of adenosine deaminase in the upper alimentary tract of mice, Differentiation, 42, 172, 10.1111/j.1432-0436.1990.tb00759.x
Witte, 1991, Coordinate developmental reguation of purine catabolic enzyme expression in gastrointestinal and postimplantation reproductive tracts, J. Cell. Biol., 115, 179, 10.1083/jcb.115.1.179
Burridge, 1976, Utilization of dietary nucleic acid purines for nucleotide and nucleic acid synthesis in the mouse, Can. J. Biochem., 54, 500, 10.1139/o76-072
Saviano, 1978, Absorption, tissue incorporation and excretion of free purine bases in the rat, Nutr. Rep. Int., 17, 551
Gross, 1991, The effect of nutritional state and allopurinol on nucleotide formation in enterocytes from the guinea pig small intestine, Biochim. Biophys. Acta, 1073, 260, 10.1016/0304-4165(91)90130-9
Gross, 1988, Effect of nutritional state and allopurinol on purine metabolism in the rat small intestine, Biochim. Biophys. Acta, 966, 168, 10.1016/0304-4165(88)90140-7
Westerfeld, 1951, Liver and intestinal xanthine oxidases in relation to diet, J. Biochem., 192, 35
MacKinnon, 1973, Purine nucleotide biosynthesis in gastrointestinal mucosa, Biochim. Biophys. Acta, 319, 1, 10.1016/0005-2787(73)90034-8
Kolassa, 1977, Salvage of adenosine, inosine, hypoxanthine, and adenine by the isolated epithelium of guinea pig jejunum, Can. J. Physiol. Pharmacol., 55, 1039, 10.1139/y77-143
Bissonnette, 1992, The de novo and salvage pathways for the synthesis of pyrimidine residues of RNA predominate in different locations within the mouse doudenal epithelium, Cell Tissue Res., 267, 131, 10.1007/BF00318699
Zaharevitz, 1990, De novo synthesis of uracil nucleotides in mouse liver and intestine studied using [15N]alanine, Eur. J. Biochem., 187, 437, 10.1111/j.1432-1033.1990.tb15507.x
Saviano, 1981, Adenine, the precursor of nucleic acids in intestinal cells unable to synthesize purines de novo, J. Nutr., 111, 1816, 10.1093/jn/111.10.1816
LeLeiko, 1983, De novo purine nucleotide synthesis in the rat small and large intestine: effect of dietary protein and purines, J. Pediatr. Gastroenterol. Nutr., 2, 313, 10.1097/00005176-198305000-00018
LeLeiko, 1987, Tissue-specific gene expression results from a purine- and pyrimidine-free diet and 6-mercaptopurine in the rat small intestine and colon, Gastroenterol., 93, 1014, 10.1016/0016-5085(87)90564-6
Uauy, 1990, Effect of dietary nucleosides on growth and maturation of the developing gut in the rat, J. Pediatr. Gastroenterol. Nutr., 10, 497, 10.1097/00005176-199005000-00014
Carver, 1993, Dietary nucleotides may act as growth factors in liver and intestine, FASEB J., 7, A643
Carver, 1994, Dietary nucleotides: cellular immune, intestinal and hepatic system effects, J. Nutr., 124, 144S, 10.1093/jn/124.suppl_1.144S
Tsujunaka, 1993, Role of nucleosides and nucleotide mixture in intestinal mucosal growth under total parenteral nutrition, Nutrition, 9, 532
Iijima, 1993, Intravenous administration of nucleosides and a nucleotide mixture diminishes intestinal mucosal atrophy induced by total parentaral nutrition, J. Paren. Ent. Nutr., 17, 265, 10.1177/0148607193017003265
Bustamante, 1990, Intestinal hyeremia evoked by nucleotides in newborn swine, Ped. Res., 27, 102A
Bustamante, 1994, Dietary nucleotides: effects on the gastrointestinal system in swine, J. Nutr., 124, 149S, 10.1093/jn/124.suppl_1.149S
Nunez, 1990, Effect of dietary nucleotides on intestinal repair in rats with experimental chronic diarrhea, J. Parenter. Enter. Nutr., 14, 598, 10.1177/0148607190014006598
Quan, 1991, Effect of dietary nucleosides (DN) on intestinal growth and maturation after injury from radiation, Pediatr. Res., 29, 111A
Grisham, 1989, Adenosine inhibits ischemia-reperfusion-induced leukocyte adherence and extravasation, Am. J. Physiol., 257, H1334
Asako, 1993, Leukocyte adherence in rat mesenteric venules: effects of adenosine and methotrexate, Gastroenterology, 104, 31, 10.1016/0016-5085(93)90832-W
Halliwell, 1984, Oxygen toxicity, oxygen radicals, transition metals and disease, Biochem. J., 219, 1, 10.1042/bj2190001
Idstrom, 1990, Purine metabolism after in vivo ischemia and reperfusion in rat skeletal muscle, Am. J. Physiol., 258, H1668
Ekman, 1991, Changes in gastric mucosal microcirculation and purine nucleotide metabolism during hemorrhagic shock in rats, Scand. J. Gastroenterol, 26, 652, 10.3109/00365529109043640
Gyorgy, 1954, Bifidus Factor. I. A variant of Lactobacillus bifidus requiring a special growth factor, Arch. Biochem. Biophys., 48, 193, 10.1016/0003-9861(54)90323-9
Tanaka, 1980, Improved medium for selective isolation and enumeration of Bifodobacterium, Appl. Environ. Microbiol., 40, 866, 10.1128/AEM.40.5.866-869.1980
He, 1993, Nucleotide supplements alter proliferation and differentiation of culture human (Caco-2) and rat (IEC-6) intestinal epithelial cells, J. Nutr., 123, 1017
Sanderson, 1994, Nucleotide uptake and metabolism by intestinal epithelial cells, J. Nutr., 124, 131S, 10.1093/jn/124.suppl_1.131S
Pritchard, 1975, Uptake and supply of purine compounds by the liver, Am. J. Physiol., 229, 967, 10.1152/ajplegacy.1975.229.4.967
Levine, 1974, A Review: Biological and clinical aspects of pyrimidine metabolism, Pediatr. Res., 8, 724, 10.1203/00006450-197407000-00008
Gasser, 1981, Novel single-pass exchange of circulating uridine in rat liver, Science, 213, 777, 10.1126/science.7256279
Holstege, 1991, Facilitated diffusion and sodium-dependent transport of purine and pyrimidine nucleosides in rat liver, Hepatology, 14, 373, 10.1002/hep.1840140226
Ohyanagi, 1989, Effects of nucleosides and a nucleotide on DNA and RNA syntheses by the salvage and de novo pathway in primary monolayer cultures of hepatocytes and hepatoma cells, J. Parenter. Enter. Nutr., 13, 51, 10.1177/014860718901300151
Yamaguchi, 1985, Diadenosine tetraphosphate as a signal molecule linked with the functional state of rat liver, Gastroenterology, 89, 723, 10.1016/0016-5085(85)90565-7
Skold, 1960, Enzymes of uracil metabolism in tissues with different growth characteristics, Biochim. Biophys. Acta, 44, 1, 10.1016/0006-3002(60)91515-8
Ogoshi, 1988, Effects of total parenteral nutrition with nucleoside and nucleotide mixture on D-galactosamine-induced liver injury in rats, J. Parenter. Enter. Nutr., 12, 53, 10.1177/014860718801200153
Ogoshi, 1985, Effect of nucleotide and nucleoside mixture on rats given total parenteral nutrition after 70% hepatectomy, J. Parenter. Enter. Nutr., 9, 339, 10.1177/0148607185009003339
Jin, 1994, Influence of nucleoside-nucleotide mixture infusion on hepatic energy metabolism of 70% hepatectomized rabbits in a postoperative phase, J. Parent. Enter. Nutr., 18, 24S
Yamaguchi, 1992, A mixture of nucleosides and a nucleotide alters hepatic energy metabolism 24 hours after hepatectomy in rabbits, J. Nutr., 122, 340, 10.1093/jn/122.2.340
Nilson, 1992, Pyrimidine-enhanced purine uptake in hepatocytes and improved survival from hypovolemic shock, Circulatory Shock, 37, 274
Saviano, 1980, Metabolism of orally and intravenously administered purines in rats, J. Nutr., 110, 1793, 10.1093/jn/110.9.1793
Lautt, 1985, Adenosine as putative regulator of hepatic arterial flow (the buffer response), Am. J. Physiol., 248, H331
Barankiewicz, 1987, Purine nucleotide metabolism in phytohemagglutinin-induced human T lymphocytes, Arch. Biochem. Biophys., 258, 167, 10.1016/0003-9861(87)90333-X
Spaapen, 1986, Intracellular purine and pyrimidine nucleotide pools of human T and B lymphocytes, Adv. Exp. Med. Biol., 195A, 567, 10.1007/978-1-4684-5104-7_95
Smith, 1989, Nucleoside transport and proliferative rate in human thymocytes and lymphocytes, Blood, 74, 2038, 10.1182/blood.V74.6.2038.2038
Cohen, 1984, Purine metabolism in human T lymphocytes: role of the purine nucleoside cycle, Can. J. Biochem. Cell Biol., 62, 557, 10.1139/o84-077
Perignon, 1987, Metabolism of pyrimidine bases and nucleosides by pyrimidine-nucleoside phosphorylases in cultured human lymphoid cells, Biochim. Biophys. Acta., 928, 130, 10.1016/0167-4889(87)90113-3
Marijnen, 1989, Studies on the incorporation of precursors into purine and pyrimidine nucleotides via ‘de novo’ and ‘salvage’ pathways in normal lymphocytes and lymphoblastic cell-line cells, Biochem. Biophys. Acta, 1012, 148, 10.1016/0167-4889(89)90088-8
Kulkarni, 1984, Functional impairment of T-lymphocytes in mouse radiation chimeras by a nucleotide-free diet, Exp. Hematol., 12, 694
Van Buren, 1983, Synergistic effect of a nucleotide-free diet and cyclosporine on allograft survival, 15, 2967
Van Buren, 1983, The influence of dietary nucleotides on cell-mediated immunity, Transplantation, 36, 350, 10.1097/00007890-198309000-00028
Kulkarni, 1987, Modulation of delayed hypersensitivity in mice by dietary nucleotide restriction, Transplantation, 44, 847
Pizzini, 1990, Dietary nucleotides reverse malnutrition and starvation-induced immunosuppression, Arch. Surg., 125, 86, 10.1001/archsurg.1990.01410130092012
Van Buren, 1990, Reversal of immunosuppression induced by a protein-free diet: comparison of nucleotides, fish oil and arginine, Crit. Care Med., 18, S114, 10.1097/00003246-199002003-00004
Carver, 1990, Dietary nucleotide effects upon murine natural killer cell activity and macrophage activation, J. Parenter. Enter. Nutr., 14, 18, 10.1177/014860719001400118
Kulkarni, 1986, Influence of dietary nucleotide restriction on bacterial sepsis and phagocytic cell function in mice, Arch. Surg., 121, 169, 10.1001/archsurg.1986.01400020055006
Kulkarni, 1986, Effect of dietary nucleotides on response to bacterial infections, J. Parenter. Enter. Nutr., 10, 169, 10.1177/0148607186010002169
Fanslow, 1988, Effect of nucleotide restriction and supplementation on resistance to experimental murine candidiasis, J. Parenter. Enter. Nutr., 12, 49, 10.1177/014860718801200149
Van Buren, 1985, Dietary nucleotides, a requirement for helper/inducer T lymphocytes, Transplantation, 40, 694, 10.1097/00007890-198512000-00024
Kulkarni, 1989, Expression of immune cell surface markers in vivo and immune competence in mice by dietary nucleotides, 21, 121
Adjei, 1993, The effects of oral RNA and intraperitoneal nucleoside-nucleotide administration on methicillin- resistant Staphylococcus aureus infection in mice, J. Parenter. Enter. Nutr., 17, 148, 10.1177/0148607193017002148
Yamamoto, 1993, Nucleoside-nucleotide mixture and its components and response to methicillin-resistant Staphylococcus aureus infection in mice, Nutrition, 9, 524
Rudolph, 1986, Effect of dietary nucleotides on lymphocyte maturation, Adv. Exp. Med. Biol., 195A, 497, 10.1007/978-1-4684-5104-7_83
Kulkarni, 1992, Immunohemopoietic effects of dietary nucleotide restriction in mice, Transplantation, 53, 467, 10.1097/00007890-199202010-00038
Rudolph, 1990, Nutrition, 6, 45
Jyonouchi, 1992, RNA/nucleotide enhances antibody production in vitro and is moderately mitogenic to murine spleen lymphocytes, 200, 101
Jyonouchi, 1993, Immunomodulating actions of RNA and nucleotides on murine lymphocytes in vitro: augmentation of antibody production to T-dependent antigens and expansion of T-helper cells, J. Nutr. Immunol., 22, 5
Jyonouchi, 1993, RNA/nucleotides enhance in vitro antibody and immunoglobulin production to T-dependent antigen but do not facilitate polyclonal B cell activation in both normal and autoimmune prone NZB strain of mice, J. Nutr. Immunol.
Jyonouchi, 1993, Studies of immunomodulating actions of RNA/nucleotides. RNA/nucleotides enhance in vitro immunoglobulin production by human peripheral blood mononuclear cells in response to T-dependent stimuli, Pediatr. Res., 33, 458, 10.1203/00006450-199305000-00008
Jyonouchi, 1994, Nucleotide actions on humoral immune responses, J. Nutr., 124, 144S, 10.1093/jn/124.suppl_1.138S
Zhang, 1993, Immunomodulating actions of nucleotides on AbIg production by murine spleen lymphocytes in vivo and in vitro, FASEB J., 7, A413
Jyonouchi, 1994, Nucleotide-free diet impairs T-helper cell functions in antibody production in response to T-dependent antigens in normal C57B16 mice, J. Nutr., 124, 475, 10.1093/jn/124.4.475
Mosley, 1992, Peripheral engraftment of fetal intestine into athymic mice sponsors T cell development: direct evidence for thymopoietic function of murine small intestine, J. Exp. Med., 176, 1365, 10.1084/jem.176.5.1365
Cerra, 1990, Effect of enteral nutrient on in vitro tests of immune function in ICU patients: a preliminary report, Nutrition, 6, 84
Daly, 1992, Enteral nutrition with supplemental arginine, RNA, and omega-3 fatty acids in patients after operation: immunologic, metabolic, and clinical outcome, Surgery, 112, 56
Chandra, 1991, Effect of two feeding formulas on immune responses and mortality in mice challenged with Listeria monocytogenes, Immunol Lett., 27, 45, 10.1016/0165-2478(91)90242-3
Uauy, 1984, Fatty acid profile of RBC membrane phospholipids: effects of diet and postnatal age, Ped Res., 18, 215A, 10.1203/00006450-198404001-00734
Ramirez, 1991, Effect of dietary nucleotides and orotate on the blood levels of prostacyclin (PGI2) and thromboxane (TXA2) in the weanling rat, 43, 49
Boza, 1992, Influences of postnatal age and dietary nucleotides on plasma fatty acids in the weanling rat, JPEN, 16, 322, 10.1177/0148607192016004322
Jimenez, 1992, Changes in fatty acid profiles of red blood cell membranes mediated by dietary nucleotides in weanling rats, J. Pediatr. Gastroenterol. Nutr., 14, 293, 10.1097/00005176-199204000-00010
Henderson, 1994, Red blood cell phospholipid docosahexaenoic acid and arachidonic acid concentrations in very low birthweight infants are not affected by nucleotide supplementation of preemie formula and are lower than in mother's own milk-fed infants, Pediatr. Res., 35, 313A
Story, 1977, Effects of dietary protein, adenine, and allopurinol on growth and metabolism of rats, J. Nutr., 107, 1044, 10.1093/jn/107.6.1044
Brule, 1988, Differences in uricogenic effects of dietary purine bases, nucleosides and nucleotides in rats, J. Nutr., 118, 780, 10.1093/jn/118.6.780
Mosqueda-Garcia, 1992, Adenosine as a therapeutic agent, Clin. Invest. Med., 15, 445
Berne, 1983, Adenosine in the local regulation of blood flow: a brief overview, 42, 3136
Buxton, 1987, Stimulation of glycogenolysis and vasoconstriction by adenosine and adenosine analogues in the perfused rat liver, Biochem. J., 248, 35, 10.1042/bj2480035
Granger, 1978, Effects of adenosine on intestinal hemodynamics, oxygen delivery, and capillary fluid exchange, Am. J. Physiol., 235, H707
Granger, 1980, Role of adenosine in local control of intestinal circulation in the dog, Circ. Res., 46, 764, 10.1161/01.RES.46.6.764
Sawmiller, 1988, Adenosine plays a role in food-induced jejunal hyperemia, Am. J. Physiol., 255, G168
Wallus, 1981, Effects of adenosine and its derivatives on the canine intestinal vasculature, Gastroenterology, 81, 327, 10.1016/S0016-5085(81)80065-0
Sawmiller, 1991, Adenosine is a vasodilator in the intestinal mucosa, Am. J. Physiol., 261, G9
Sawmiller, 1992, Role of adenosine in postprandial and reactive hyperemia in canine jejunum, Am. J. Physiol., 263, G487
Sawmiller, 1990, Jejunal adenosine increases during food-induced jejunal hyperemia, Am. J. Physiol., 258, G370
Proctor, 1986, Possible role for adenosine in local regulation of absorptive hyperemia in rat intestine, Circ. Res., 59, 474, 10.1161/01.RES.59.4.474
Kaminski, 1992, Extracellular and intracellular actions of adenosine and related compounds in the reperfused rat intestine, Circ. Res., 71, 720, 10.1161/01.RES.71.3.720
Furukawa, 1989, Postnatal changes in response to adenosine and adenine nucleotides in rat duodenum, Br. J. Pharmacol., 97, 1111, 10.1111/j.1476-5381.1989.tb12568.x
Rathbone, 1992, Extracellular purine nucleosides stimulate cell division and morphogenesis: pathological and physiological implications, Medical Hypothesis, 37, 232, 10.1016/0306-9877(92)90193-G
Adair, 1990, Role of adenosine in the regulation of blood vessel growth, Jpn. J. Pharm., 52, 50P, 10.1016/S0021-5198(19)32923-3
Newby, 1984, Adenosine and the concept of ‘retaliatory metabolites’, Trends Biochem. Sci., 9, 42, 10.1016/0968-0004(84)90176-2
Campoli-Richards, 1986, Inosine Pranobex. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, Drugs, 32, 383, 10.2165/00003495-198632050-00001
Hadden, 1991, Methyl inosine monophosphate (MIMP), a new purine immunomodulator for HIV infection, Int. J. Immunopharmac., 13, 49, 10.1016/0192-0561(91)90124-P
Sosa, 1992, Potentiation of immune responses in mice by a new inosine derivative—methyl inosine monophosphate (MIMP), Int. J. Immunopharmacol., 14, 1259, 10.1016/0192-0561(92)90062-P
Bekeski, 1987, Immunorestorative properties of isoprinosine in the treatment at patients at high risk of developing ARC or AIDS, J. Clin. Lab Immun., 24, 155
Hoehler, 1988, Incidence of acquired immune deficiency syndrome in patients with persistent generalized lymphadenopathy: immunologic risk factors and effects of shortterm immunotherapy with inosine pranobex, Curr. Ther. Res., 43, 688
Pederson, 1990, The efficacy of inosine pranobex in preventing the acquired immunodeficiency syndrome in patients with human immunodeficiency virus infection, New Engl. J. Med., 322, 1757, 10.1056/NEJM199006213222501
DeSimone, 1988, Clinical and immunological assessment in HIV + subjects receiving inosine-pranobex: a randomized, multicenteric study, Med. Oncol. Tumor Pharmacother., 10, 299
Hadden, 1983, Purine analogs as immunomodulators, Vol. VI, 1393