The role of nicotinic acetylcholine receptors in Alzheimer’s disease

Journal of Physiology-Paris - Tập 99 Số 2-3 - Trang 172-179 - 2006
Salvatore Oddo1, Frank M. LaFerla2
1Department of Neurobiology and Behavior, University of California, Irvine, 1109 Gillespie Neuroscience Building, Irvine, CA 92697-4545, USA.
2University of California, at Irvine#TAB#

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Almeida, 2002, Smoking as a risk factor for Alzheimer’s disease: contrasting evidence from a systematic review of case-control and cohort studies, Addiction, 97, 15, 10.1046/j.1360-0443.2002.00016.x

Aubert, 1992, Comparative alterations of nicotinic and muscarinic binding sites in Alzheimer’s and Parkinson’s diseases, J. Neurochem., 58, 529, 10.1111/j.1471-4159.1992.tb09752.x

Billings, 2005, Intraneuronal Abeta causes the onset of early Alzheimer’s disease-related cognitive deficits in transgenic mice, Neuron, 45, 675, 10.1016/j.neuron.2005.01.040

Burghaus, 2000, Quantitative assessment of nicotinic acetylcholine receptor proteins in the cerebral cortex of Alzheimer patients, Brain Res. Mol. Brain Res., 76, 385, 10.1016/S0169-328X(00)00031-0

Court, 2005, Attenuation of Abeta deposition in the entorhinal cortex of normal elderly individuals associated with tobacco smoking, Neuropathol. Appl. Neurobiol., 31, 522, 10.1111/j.1365-2990.2005.00674.x

Davies, 1976, Selective loss of central cholinergic neurons in Alzheimer’s disease, Lancet, 2, 1403, 10.1016/S0140-6736(76)91936-X

Dineley, 2001, Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: in vitro and in vivo mechanisms related to Alzheimer’s disease, J. Neurosci., 21, 4125, 10.1523/JNEUROSCI.21-12-04125.2001

Flynn, 1986, Characterization of L-[3H]nicotine binding in human cerebral cortex: comparison between Alzheimer’s disease and the normal, J. Neurochem., 47, 1948, 10.1111/j.1471-4159.1986.tb13113.x

Fodero, 2004, Alpha 7-nicotinic acetylcholine receptors mediate an Abeta(1–42)-induced increase in the level of acetylcholinesterase in primary cortical neurones, J. Neurochem., 88, 1186, 10.1046/j.1471-4159.2003.02296.x

Frazier, 1998, Synaptic potentials mediated via alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal interneurons, J. Neurosci., 18, 8228, 10.1523/JNEUROSCI.18-20-08228.1998

Freir, 2001, Blockade of long-term potentiation by beta-amyloid peptides in the CA1 region of the rat hippocampus in vivo, J. Neurophysiol., 85, 708, 10.1152/jn.2001.85.2.708

Gotti, 2004, Neuronal nicotinic receptors: from structure to pathology, Prog. Neurobiol., 74, 363, 10.1016/j.pneurobio.2004.09.006

Hellstrom-Lindahl, 1999, Regional distribution of nicotinic receptor subunit mRNAs in human brain: comparison between Alzheimer and normal brain, Brain. Res. Mol. Brain. Res., 66, 94, 10.1016/S0169-328X(99)00030-3

Hellstrom-Lindahl, 2000, Increased levels of tau protein in SH-SY5Y cells after treatment with cholinesterase inhibitors and nicotinic agonists, J. Neurochem., 74, 777, 10.1046/j.1471-4159.2000.740777.x

Hellstrom-Lindahl, 2004, Nicotine reduces A beta in the brain and cerebral vessels of APPsw mice, Eur. J. Neurosci., 19, 2703, 10.1111/j.0953-816X.2004.03377.x

Howe, 2001, Effects of transdermal nicotine on learning, memory, verbal fluency, concentration, and general health in a healthy sample at risk for dementia, Int. Psychogeriatr., 13, 465, 10.1017/S1041610201007888

Hsiao, 1996, Correlative memory deficits, abeta elevation, and amyloid plaques in transgenic mice, Science, 274, 99, 10.1126/science.274.5284.99

Ji, 2001, Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity, Neuron, 31, 131, 10.1016/S0896-6273(01)00332-4

Jones, 1992, Effects of acute subcutaneous nicotine on attention information processing and short-term memory in Alzheimer’s disease, Psychopharmacol. (Berl.), 108, 485, 10.1007/BF02247426

Juan, 2004, A 2-year follow-up study of cigarette smoking and risk of dementia, Eur. J. Neurol., 11, 277, 10.1046/j.1468-1331.2003.00779.x

Karlin, 2002, Emerging structure of the nicotinic acetylcholine receptors, Nat. Rev. Neurosci., 3, 102, 10.1038/nrn731

Kihara, 1998, Stimulation of alpha4beta2 nicotinic acetylcholine receptors inhibits beta-amyloid toxicity, Brain Res., 792, 331, 10.1016/S0006-8993(98)00138-3

Kitazawa, 2005, Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer’s disease, J. Neurosci., 25, 8843, 10.1523/JNEUROSCI.2868-05.2005

Kukull, 2001, The association between smoking and Alzheimer’s disease: effects of study design and bias, Biol. Psychiat., 49, 194, 10.1016/S0006-3223(00)01077-5

Lambon Ralph, 2003, Homogeneity and heterogeneity in mild cognitive impairment and Alzheimer’s disease: a cross-sectional and longitudinal study of 55 cases, Brain, 126, 2350, 10.1093/brain/awg236

Letenneur, 2004, Alcohol and tobacco consumption as risk factors of dementia: a review of epidemiological studies, Biomed. Pharmacother., 58, 95, 10.1016/j.biopha.2003.12.004

Lindstrom, 1997, Nicotinic acetylcholine receptors in health and disease, Mol. Neurobiol., 15, 193, 10.1007/BF02740634

Liu, 2001, Beta-amyloid peptide blocks the response of alpha 7-containing nicotinic receptors on hippocampal neurons, Proc. Natl. Acad. Sci. USA, 98, 4734, 10.1073/pnas.081553598

Martin-Ruiz, 1999, Alpha4 but not alpha3 and alpha7 nicotinic acetylcholine receptor subunits are lost from the temporal cortex in Alzheimer’s disease, J. Neurochem., 73, 1635, 10.1046/j.1471-4159.1999.0731635.x

Marutle, 1999, nicotinic receptor deficits in Alzheimer patients with the Swedish amyloid precursor protein 670/671 mutation, J. Neurochem., 72, 1161, 10.1046/j.1471-4159.2000.0721161.x

McGeer, 1984, Aging, Alzheimer’s disease, and the cholinergic system of the basal forebrain, Neurology, 34, 741, 10.1212/WNL.34.6.741

McGehee, 1995, Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors, Science, 269, 1692, 10.1126/science.7569895

Morens, 1994, Smoking-associated protection from Alzheimer’s and Parkinson’s disease, Lancet, 343, 356, 10.1016/S0140-6736(94)91194-0

Mousavi, 2003, Protein and mRNA levels of nicotinic receptors in brain of tobacco using controls and patients with Alzheimer’s disease, Neuroscience, 122, 515, 10.1016/S0306-4522(03)00460-3

Muir, 1997, Acetylcholine, aging, and Alzheimer’s disease, Pharmacol. Biochem. Behav., 56, 687, 10.1016/S0091-3057(96)00431-5

Newhouse, 1988, Intravenous nicotine in Alzheimer’s disease: a pilot study, Psychopharmacol. (Berl.), 95, 171, 10.1007/BF00174504

Nordberg, 1988, Change in nicotinic receptor subtypes in temporal cortex of Alzheimer brains, Neurosci. Lett., 86, 317, 10.1016/0304-3940(88)90503-4

Nordberg, 1990, Decreased uptake and binding of 11C-nicotine in brain of Alzheimer patients as visualized by positron emission tomography, J. Neural. Transm. Park. Dis. Dement. Sect., 2, 215, 10.1007/BF02257652

Nordberg, 1995, Kinetic analysis of regional (S)(−)11C-nicotine binding in normal and Alzheimer brains—in vivo assessment using positron emission tomography, Alzheimer. Dis. Assoc. Disord., 9, 21, 10.1097/00002093-199505000-00006

Nordberg, 1997, Imaging of nicotinic and muscarinic receptors in Alzheimer’s disease: effect of tacrine treatment, Dement. Geriatr. Cogn. Disord., 8, 78, 10.1159/000106611

Nordberg, 2002, Chronic nicotine treatment reduces beta-amyloidosis in the brain of a mouse model of Alzheimer’s disease (APPsw), J. Neurochem., 81, 655, 10.1046/j.1471-4159.2002.00874.x

Nordberg, 1986, Reduced number of [3H]nicotine and [3H]acetylcholine binding sites in the frontal cortex of Alzheimer brains, Neurosci. Lett., 72, 115, 10.1016/0304-3940(86)90629-4

Oddo, 2003, Triple-transgenic model of Alzheimer’s disease with plaques and tangles: intracellular Abeta and synaptic dysfunction, Neuron, 39, 409, 10.1016/S0896-6273(03)00434-3

Oddo, 2005, Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer’s disease, Proc. Natl. Acad. Sci. USA, 102, 3046, 10.1073/pnas.0408500102

Ono, 2002, Nicotine breaks down preformed Alzheimer’s beta-amyloid fibrils in vitro, Biol. Psychiat., 52, 880, 10.1016/S0006-3223(02)01417-8

Ott, 2004, Effect of smoking on global cognitive function in nondemented elderly, Neurology, 62, 920, 10.1212/01.WNL.0000115110.35610.80

Parks, 1996, Increased regional cerebral glucose metabolism and semantic memory performance in Alzheimer’s disease: a pilot double blind transdermal nicotine positron emission tomography study, Neuropsychol. Rev., 6, 61, 10.1007/BF01875368

Perry, 1990, Cholinergic nicotinic and muscarinic receptors in dementia of Alzheimer, Parkinson and Lewy body types, J. Neural. Transm. Park. Dis. Dement. Sect., 2, 149, 10.1007/BF02257646

Perry, 1995, Alteration in nicotine binding sites in Parkinson’s disease, Lewy body dementia and Alzheimer’s disease: possible index of early neuropathology, Neuroscience, 64, 385, 10.1016/0306-4522(94)00410-7

Provost, 1991, Effects of nicotine gum on repeated administration of the Stroop test, Psychopharmacol. (Berl.), 104, 536, 10.1007/BF02245662

Rinne, 1991, A postmortem study of brain nicotinic receptors in Parkinson’s and Alzheimer’s disease, Brain Res., 547, 167, 10.1016/0006-8993(91)90588-M

Sabbagh, 2005, Smoking affects the phenotype of Alzheimer disease, Neurology, 64, 1301, 10.1212/01.WNL.0000156912.54593.65

Sahakian, 1989, The effects of nicotine on attention, information processing, and short-term memory in patients with dementia of the Alzheimer type, Br. J. Psychiat., 154, 797, 10.1192/bjp.154.6.797

Salomon, 1996, Nicotine inhibits amyloid formation by the beta-peptide, Biochemistry, 35, 13568, 10.1021/bi9617264

Shimohama, 1986, Changes in nicotinic and muscarinic cholinergic receptors in Alzheimer-type dementia, J. Neurochem., 46, 288, 10.1111/j.1471-4159.1986.tb12960.x

Snaedal, 1996, The effects of nicotine in dermal plaster on cognitive functions in patients with Alzheimer’s disease, Dementia, 7, 47

Sparks, 1998, Immunohistochemical localization of nicotinic beta2 and alpha4 receptor subunits in normal human brain and individuals with Lewy body and Alzheimer’s disease: preliminary observations, Neurosci. Lett., 256, 151, 10.1016/S0304-3940(98)00794-0

Sugaya, 1990, Nicotinic acetylcholine receptor subtypes in human frontal cortex: changes in Alzheimer’s disease, J. Neurosci. Res., 27, 349, 10.1002/jnr.490270314

Terzano, 1998, Expression of the alpha3 nicotinic receptor subunit mRNA in aging and Alzheimer’s disease, Brain Res. Mol. Brain Res., 63, 72, 10.1016/S0169-328X(98)00260-5

Tyas, 2003, Mid-life smoking and late-life dementia the Honolulu-Asia Aging Study, Neurobiol. Aging, 24, 589, 10.1016/S0197-4580(02)00156-2

Ulrich, 1997, Does smoking protect from Alzheimer’s disease? Alzheimer-type changes in 301 unselected brains from patients with known smoking history, Acta. Neuropathol. (Berl.), 94, 450, 10.1007/s004010050732

Wang, 1999, Smoking and the occurrence of Alzheimer’s disease: cross-sectional and longitudinal data in a population-based study, Am. J. Epidemiol., 149, 640, 10.1093/oxfordjournals.aje.a009864

Wang, 2000, Beta-Amyloid (1–42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer’s disease pathology, J. Biol. Chem., 275, 5626, 10.1074/jbc.275.8.5626

Wang, 2003, Alpha 7 nicotinic acetylcholine receptors mediate beta-amyloid peptide-induced tau protein phosphorylation, J. Biol. Chem., 278, 31547, 10.1074/jbc.M212532200

Wevers, 1999, Expression of nicotinic acetylcholine receptor subunits in the cerebral cortex in Alzheimer’s disease: histotopographical correlation with amyloid plaques and hyperphosphorylated-tau protein, Eur. J. Neurosci., 11, 2551, 10.1046/j.1460-9568.1999.00676.x

Wevers, 1999, Nicotinic acetylcholine receptors in Alzheimer’s disease, J. Alzheimers Dis., 1, 207, 10.3233/JAD-1999-14-503

White, 1999, Four-week nicotine skin patch treatment effects on cognitive performance in Alzheimer’s disease, Psychopharmacol. (Berl.), 143, 158, 10.1007/s002130050931

Wilson, 1995, Nicotine patches in Alzheimer’s disease: pilot study on learning, memory, and safety, Pharmacol. Biochem. Behav., 51, 509, 10.1016/0091-3057(95)00043-V

Woolf, 1996, The critical role of cholinergic basal forebrain neurons in morphological change and memory encoding: a hypothesis, Neurobiol. Learn. Mem., 66, 258, 10.1006/nlme.1996.0068