The role of miRNAs in multiple sclerosis pathogenesis, diagnosis, and therapeutic resistance
Tài liệu tham khảo
Doshi, 2017, Multiple sclerosis, a treatable disease, Clin. Med., 17, 530, 10.7861/clinmedicine.17-6-530
Wallin, 2019, Global, regional, and national burden of multiple sclerosis 1990–2016: a systematic analysis for the global burden of disease study 2016, Lancet Neurol., 18, 269, 10.1016/S1474-4422(18)30443-5
Sadeghi Hassanabadi, 2022, Innate lymphoid cells - neglected players in multiple sclerosis, Front. Immunol., 13, 10.3389/fimmu.2022.909275
Browne, 2014, Atlas of multiple sclerosis 2013: a growing global problem with widespread inequity, Neurology, 83, 1022, 10.1212/WNL.0000000000000768
Alfredsson, 2019, Lifestyle and environmental factors in multiple sclerosis, Cold Spring Harb. Perspect. Med., 9, 10.1101/cshperspect.a028944
Huang, 2023, Advanced brain MRI may help understand the link between migraine and multiple sclerosis, J. Headache Pain., 24, 1, 10.1186/s10194-023-01645-7
Stadelmann, 2011, Multiple sclerosis as a neurodegenerative disease: pathology, mechanisms and therapeutic implications, Curr. Opin. Neurol., 24, 224, 10.1097/WCO.0b013e328346056f
Garg, 2015, An update on immunopathogenesis, diagnosis, and treatment of multiple sclerosis, Brain Behav., 5, 10.1002/brb3.362
Dobson, 2019, Multiple sclerosis–a review, Eur. J. Neurol., 26, 27, 10.1111/ene.13819
Graves, 2023, Ageing and multiple sclerosis, Lancet Neurol., 10.1016/S1474-4422(22)00184-3
Doghish, 2022, A review of the biological role of miRNAs in prostate cancer suppression and progression, Int. J. Biol. Macromol., 197, 141, 10.1016/j.ijbiomac.2021.12.141
Elrebehy, 2022, miRNAs as cornerstones in colorectal cancer pathogenesis and resistance to therapy: a spotlight on signaling pathways interplay—a review, Int. J. Biol. Macromol., 214, 583, 10.1016/j.ijbiomac.2022.06.134
El-Mahdy, 2022, miRNAs inspirations in hepatocellular carcinoma: detrimental and favorable aspects of key performers, Pathol. -Res. Pract., 10.1016/j.prp.2022.153886
Elsakka, 2022, Megalin, a multi-ligand endocytic receptor, and its participation in renal function and diseases: A review, Life Sci., 10.1016/j.lfs.2022.120923
Ismail, 2022, Beneficial and detrimental aspects of miRNAs as chief players in breast cancer: a comprehensive review, Int. J. Biol. Macromol.
Ismail, 2022, The role of miRNAs in ovarian cancer pathogenesis and therapeutic resistance-a focus on signaling pathways interplay, Pathol. -Res. Pract., 10.1016/j.prp.2022.154222
Hegazy, 2023, The role of miRNAs in laryngeal cancer pathogenesis and therapeutic resistance – a focus on signaling pathways interplay, Pathol. - Res. Pract., 246, 10.1016/j.prp.2023.154510
Doghish, 2022, A study of miRNAs as cornerstone in lung cancer pathogenesis and therapeutic resistance: a focus on signaling pathways interplay, Pathol. -Res. Pract., 10.1016/j.prp.2022.154053
El-Mahdy, 2023, miRNAs role in bladder cancer pathogenesis and targeted therapy: signaling pathways interplay-a review, Pathol. -Res. Pract., 10.1016/j.prp.2023.154316
Doghish, 2023, miRNAs role in cervical cancer pathogenesis and targeted therapy: signaling pathways interplay, Pathol. -Res. Pract.
Doghish, 2023, Significance of miRNAs on the thyroid cancer progression and resistance to treatment with special attention to the role of cross-talk between signaling pathways, Pathol. -Res. Pract., 10.1016/j.prp.2023.154371
Doghish, 2023, miRNAs as cornerstones in chronic lymphocytic leukemia pathogenesis and therapeutic resistance–an emphasis on the interaction of signaling pathways, Pathol. -Res. Pract.
Abdelmaksoud, 2023, The role of miRNAs in the pathogenesis and therapeutic resistance of endometrial cancer: a spotlight on the convergence of signaling pathways, Pathol. -Res. Pract., 10.1016/j.prp.2023.154411
Abd-Allah, 2023, miRNAs as potential game-changers in melanoma: a comprehensive review, Pathol. -Res. Pract., 10.1016/j.prp.2023.154424
Zaki, 2023, The interplay of signaling pathways with miRNAs in cholangiocarcinoma pathogenicity and targeted therapy, Pathol. -Res. Pract., 10.1016/j.prp.2023.154437
Fathi, 2023, An emphasis on the interaction of signaling pathways highlights the role of miRNAs in the etiology and treatment resistance of gastric cancer, Life Sci., 10.1016/j.lfs.2023.121667
Al-Noshokaty, 2023, Role of long non-coding RNAs in pancreatic cancer pathogenesis and treatment resistance-a review, Pathol. -Res. Pract., 10.1016/j.prp.2023.154438
Doghish, 2023, A spotlight on the interplay of signaling pathways and the role of miRNAs in osteosarcoma pathogenesis and therapeutic resistance, Pathol. -Res. Pract.
Elballal, 2023, miRNAs as potential game-changers in renal cell carcinoma: future clinical and medicinal uses, Pathol. - Res. Pract., 245, 10.1016/j.prp.2023.154439
El-Mahdy, 2023, miRNAs as potential game-changers in head and neck cancer: future clinical and medicinal uses, Pathol. -Res. Pract., 10.1016/j.prp.2023.154457
Allam, 2023, Androgen receptor blockade by flutamide down-regulates renal fibrosis, inflammation, and apoptosis pathways in male rats, Life Sci., 323, 10.1016/j.lfs.2023.121697
Mady, 2023, Impact of the mother's gut microbiota on infant microbiome and brain development, Neurosci. Biobehav. Rev., 10.1016/j.neubiorev.2023.105195
Doghish, 2023, The interplay of signaling pathways and miRNAs in the pathogenesis and targeted therapy of esophageal cancer, Pathol. -Res. Pract.
Elshaer, 2023, miRNAs role in glioblastoma pathogenesis and targeted therapy: signaling pathways interplay, Pathol. -Res. Pract., 10.1016/j.prp.2023.154511
Elrebehy, 2023, miR-509-5p promotes colorectal cancer cell ferroptosis by targeting SLC7A11, Pathol. Res. Pract., 10.1016/j.prp.2023.154557
Doghish, 2023, miRNAs as potential game-changers in retinoblastoma: future clinical and medicinal uses, Pathol. -Res. Pract.
Abulsoud, 2023, The potential role of miRNAs in the pathogenesis of salivary gland cancer – a Focus on signaling pathways interplay, Pathol. - Res. Pract., 247, 10.1016/j.prp.2023.154584
N.M.A. Ahmed A. El-Husseiny, Sherif S. Abdel Mageed, Aya Salman, Mohamed Bakr Zaki, Hesham A. El-Mahdy, Ahmed Ismail, Mai A. Abd-Elmawla, Hussein M. El-Husseiny, Ahmed I. Abulsouda, Shereen Saeid Elshaer, Elsayed G.E. Elsakka, Doaa Fathi, Walaa A. El-Dakroury, Ahmed S. Doghish, miRNAs orchestration of salivary gland cancer- Particular emphasis on diagnosis, progression, and drug resistance, Pathology - Research and Practice (2023).
Doghish, 2023, The potential role of miRNAs in the pathogenesis of testicular germ cell tumors - a Focus on signaling pathways interplay, Pathol. - Res. Pract.
Elesawy, 2023, miRNAs orchestration of testicular germ cell tumors - particular emphasis on diagnosis, progression and drug resistance, Pathol. - Res. Pract., 10.1016/j.prp.2023.154612
El-Dakroury, 2023, miRNAs orchestration of adrenocortical carcinoma - particular emphasis on diagnosis, progression and drug resistance, Pathol. - Res. Pract., 10.1016/j.prp.2023.154665
Doghish, 2023, The potential role of miRNAs in the pathogenesis of gallbladder cancer - a focus on signaling pathways interplay, Pathol. - Res. Pract.
Shahin, 2023, miRNAs orchestration of gallbladder cancer - particular emphasis on diagnosis, progression and drug resistance, Pathol. - Res. Pract., 10.1016/j.prp.2023.154684
Midan, 2023, The potential role of miRNAs in the pathogenesis of adrenocortical carcinoma – a focus on signaling pathways interplay, Pathol. - Res. Pract., 248, 10.1016/j.prp.2023.154690
Al-Noshokaty, 2023, miRNAs driving diagnosis, prognosis and progression in Merkel cell carcinoma, Pathol. Res. Pract., 249, 10.1016/j.prp.2023.154763
Rizk, 2023, The emerging role of miRNAs in Merkel cell carcinoma pathogenesis: signaling pathway crosstalk, Pathol. Res. Pract., 10.1016/j.prp.2023.154771
Abd-Elmawla, 2023, Melodic maestros: Unraveling the role of miRNAs in the diagnosis, progression, and drug resistance of malignant pleural mesothelioma, Pathol. - Res. Pract., 250, 10.1016/j.prp.2023.154817
Elkhawaga, 2023, Possible role of miRNAs in pheochromocytoma pathology - signaling pathways interaction, Pathol. Res. Pract., 10.1016/j.prp.2023.154856
Mohammed, 2023, From strings to signals: unraveling the impact of miRNAs on diagnosis, and progression of colorectal cancer, Pathol. - Res. Pract., 10.1016/j.prp.2023.154857
Abulsoud, 2023, Investigating the regulatory role of miRNAs as silent conductors in the management of pathogenesis and therapeutic resistance of pancreatic cancer, Pathol. - Res. Pract., 10.1016/j.prp.2023.154855
Elsakka, 2023, From diagnosis to resistance: a symphony of miRNAs in pheochromocytoma progression and treatment response, Naunyn-Schmiede 'S. Arch. Pharmacol., 10.1007/s00210-023-02759-0
Doghish, 2023, The role of miRNAs in liver diseases: Potential therapeutic and clinical applications, Pathol. - Res. Pract., 243, 10.1016/j.prp.2023.154375
Doghish, 2023, miRNAs as potential game-changers in bone diseases: future medicinal and clinical Uses, Pathol. - Res. Pract.
Elkady, 2023, miRNAs driving diagnosis, progression, and drug resistance in multiple myeloma, Pathol. - Res. Pract., 248, 10.1016/j.prp.2023.154704
Yehia, 2023, Decoding the role of miRNAs in multiple myeloma pathogenesis: a focus on signaling pathways, Pathol. - Res. Pract., 10.1016/j.prp.2023.154715
Elsakka, 2023, miRNAs orchestration of cardiovascular diseases – particular emphasis on diagnosis, and progression, Pathol. - Res. Pract., 248, 10.1016/j.prp.2023.154613
Khidr, 2023, The potential role of miRNAs in the pathogenesis of cardiovascular diseases – a focus on signaling pathways interplay, Pathol. Res. Pract., 248, 10.1016/j.prp.2023.154624
Elkady, 2021, MicroRNA-567 inhibits cell proliferation and induces cell apoptosis in A549 NSCLC cells by regulating cyclin-dependent kinase 8, Saudi J. Biol. Sci., 28, 2581, 10.1016/j.sjbs.2021.02.001
Bakr Zaki, 2019, Potential role of circulating microRNAs (486-5p, 497, 509-5p and 605) in metabolic syndrome Egyptian male patients, Diabetes, Metab. Syndr. Obes.: Targets Ther., 601, 10.2147/DMSO.S187422
Doghish, 2021, Circulating miR-148a-5p and miR-21-5p as novel diagnostic biomarkers in adult egyptian male patients with metabolic syndrome, Can. J. Diabetes, 45, 614, 10.1016/j.jcjd.2020.12.005
Doghish, 2023, The interplay between toxoplasmosis and host miRNAs: Mechanisms and consequences, Pathol. - Res. Pract., 250, 10.1016/j.prp.2023.154790
Doghish, 2023, miRNAs insights into rheumatoid arthritis: Favorable and detrimental aspects of key performers, Life Sci., 314, 10.1016/j.lfs.2022.121321
Elazazy, 2023, Long non-coding RNAs and rheumatoid arthritis: Pathogenesis and clinical implications, Pathol. - Res. Pract., 10.1016/j.prp.2023.154512
Ismail, 2023, miRNAs as cornerstones in diabetic microvascular complications, Mol. Genet. Metab., 138, 10.1016/j.ymgme.2022.106978
Abdel Mageed, 2023, The role of miRNAs in insulin resistance and diabetic macrovascular complications – A review, Int. J. Biol. Macromol., 230, 10.1016/j.ijbiomac.2023.123189
Elkhawaga, 2023, miRNAs as cornerstones in adipogenesis and obesity, Life Sci., 315, 10.1016/j.lfs.2023.121382
Doghish, 2019, Plasma endoglin in Type2 diabetic patients with nephropathy, Diabetes Metab. Syndr.: Clin. Res. Rev., 13, 764, 10.1016/j.dsx.2018.11.058
Ying, 2021, miRNAs; a novel strategy for the treatment of COVID‐19, Cell Biol. Int., 45, 2045, 10.1002/cbin.11653
Abulsoud, 2023, Mutations in SARS-CoV-2: Insights on structure, variants, vaccines, and biomedical interventions, Biomed. Pharmacother., 157, 10.1016/j.biopha.2022.113977
Ismail, 2022, Clinical and chest computed tomography features of patients suffering from mild and severe COVID-19 at Fayoum University Hospital in Egypt, Plos One, 17, 10.1371/journal.pone.0271271
Doghish, 2021, Clinical characteristics of Egyptian male patients with COVID‐19 acute respiratory distress syndrome, Plos One, 16, 10.1371/journal.pone.0249346
Liu, 2022, MicroRNAs in Alzheimer's disease: potential diagnostic markers and therapeutic targets, Biomed. Pharmacother., 148, 10.1016/j.biopha.2022.112681
K.I. Eissa, M.M. Kamel, L.W. Mohamed, A.S. Doghish, R. Alnajjar, A.A. Al‐Karmalawy, A.E. Kassab, Design, synthesis, and biological evaluation of thienopyrimidine derivatives as multifunctional agents against Alzheimer's disease, Drug Dev. Res.
Mohammed, 2023, Alvespimycin exhibits potential anti-TGF-β signaling in the setting of a proteasome activator in rats with bleomycin-induced pulmonary fibrosis: a promising novel approach, Pharmaceuticals, 16, 1123, 10.3390/ph16081123
Wang, 2021, Micrornas, multiple sclerosis, and depression, Int. J. Mol. Sci., 22, 7802, 10.3390/ijms22157802
Mycko, 2020, microRNA and exosome profiling in multiple sclerosis, Mult. Scler. J., 26, 599, 10.1177/1352458519879303
Yang, 2022, Current and future biomarkers in multiple sclerosis, Int. J. Mol. Sci., 23, 5877, 10.3390/ijms23115877
Cui, 2019, Circulating MicroRNAs in cancer: potential and challenge, Front Genet, 10, 626, 10.3389/fgene.2019.00626
El-Sheikh, 2022, Insights on the potential oncogenic impact of long non-coding RNA nicotinamide nucleotide transhydrogenase antisense RNA 1 in different cancer types; integrating pathway(s) and clinical outcome(s) association, Pathol. Res Pr., 240
Abd El Fattah, 2022, Interactome battling of lncRNA CCDC144NL-AS1: Its role in the emergence and ferocity of cancer and beyond, Int J. Biol. Macromol., 10.1016/j.ijbiomac.2022.09.209
Li, 2022, Defining disease-related modules based on weighted miRNA synergistic network, Comput. Biol. Med, 152
Bakr, 2023, Telomerase RNA component lncRNA as potential diagnostic biomarker promotes CRC cellular migration and apoptosis evasion via modulation of β-catenin protein level, Non-coding RNA Res., 8, 302, 10.1016/j.ncrna.2023.03.004
Denli, 2004, Processing of primary microRNAs by the Microprocessor complex, Nature, 432, 231, 10.1038/nature03049
Erturk, 2022, Mitochondrial miRNAs (MitomiRs): their potential roles in breast and other cancers, Mitochondrion, 10.1016/j.mito.2022.08.002
Wei, 2021, Structural basis of microRNA processing by Dicer-like 1, Nat. Plants, 7, 1389, 10.1038/s41477-021-01000-1
Newman, 2010, Emerging paradigms of regulated microRNA processing, Genes Dev., 24, 1086, 10.1101/gad.1919710
Ergin, 2022, Regulation of microRNAs, miRNomics, Springer, 1
Ruby, 2007, Intronic microRNA precursors that bypass Drosha processing, Nature, 448, 83, 10.1038/nature05983
Babiarz, 2008, Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs, Genes Dev., 22, 2773, 10.1101/gad.1705308
Salman, 2023, The long non-coding RNA ZFAS1 promotes colorectal cancer progression via miR200b/ZEB1 axis, Pathol. - Res. Pract., 247, 10.1016/j.prp.2023.154567
El-Sheikh, 2023, LncRNA NNT-AS1/hsa-miR-485–5p/HSP90 axis in-silico and clinical prospect correlated-to histologic grades-based CRC stratification: A step toward ncRNA Precision, Pathol. - Res. Pract., 247, 10.1016/j.prp.2023.154570
Pérez, 2022, MicroRNAs as a possible biomarker in the treatment of multiple sclerosis, IBRO Neurosci. Rep., 13, 492, 10.1016/j.ibneur.2022.11.001
Al-Warhi, 2022, Identification of novel cyanopyridones and pyrido [2, 3-D] pyrimidines as anticancer agents with dual VEGFR-2/HER-2 inhibitory action: synthesis, biological evaluation and molecular docking studies, Pharmaceuticals, 15, 1262, 10.3390/ph15101262
Ismail, 2022, Hydroxycitric acid reverses tamoxifen resistance through inhibition of ATP citrate lyase, Pathol. -Res. Pract., 240, 10.1016/j.prp.2022.154211
Ismail, 2020, Hydroxycitric acid potentiates the cytotoxic effect of tamoxifen in MCF-7 breast cancer cells through inhibition of ATP citrate lyase, Steroids, 160, 10.1016/j.steroids.2020.108656
Eissa, 2023, New theobromine derivative as apoptotic anti-triple-negative breast cancer targeting EGFR protein: CADD story, J. Mol. Struct., 1294, 10.1016/j.molstruc.2023.136336
Kassab, 2021, Design, synthesis, anticancer evaluation, and molecular modelling studies of novel tolmetin derivatives as potential VEGFR-2 inhibitors and apoptosis inducers, J. Enzym. Inhib. Med. Chem., 36, 922, 10.1080/14756366.2021.1901089
Azmy, 2023, Development of pyrolo[2,3-c]pyrazole, pyrolo[2,3-d]pyrimidine and their bioisosteres as novel CDK2 inhibitors with potent in vitro apoptotic anti-proliferative activity: Synthesis, biological evaluation and molecular dynamics investigations, Bioorg. Chem., 10.1016/j.bioorg.2023.106729
Shehabeldine, 2023, Antimicrobial, Antibiofilm, and Anticancer Activities of Syzygium aromaticum Essential Oil Nanoemulsion, Molecules, 28, 5812, 10.3390/molecules28155812
Ragab, 2023, The journey of boswellic acids from synthesis to pharmacological activities, Naunyn-Schmiede 'S. Arch. Pharmacol., 10.1007/s00210-023-02725-w
Doghish, 2023, Thymus vulgaris oil nanoemulsion: synthesis, characterization, antimicrobial and anticancer activities, Molecules, 28, 6910, 10.3390/molecules28196910
Doghish, 2022, Nanocomposite based on gold nanoparticles and carboxymethyl cellulose: synthesis, characterization, antimicrobial, and anticancer activities, J. Drug Deliv. Sci. Technol., 77
Doghish, 2021, Rouby, Graphene oxide and its nanocomposites with EDTA or chitosan induce apoptosis in MCF-7 human breast cancer, RSC Adv., 11, 29052, 10.1039/D1RA04345E
Salem, 2022, Synthesis of silver nanocomposite based on carboxymethyl cellulose: antibacterial, antifungal and anticancer activities, Polymers, 14, 3352, 10.3390/polym14163352
Elkady, 2022, New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies, J. Enzym. Inhib. Med. Chem., 37, 403, 10.1080/14756366.2021.2015343
Ghanem, 2023, Rumex vesicarius L. boosts the effectiveness of sorafenib in triple-negative breast cancer by downregulating BCl2, mTOR, and JNK, and upregulating p21 expression, Pathol. - Res. Pract., 250, 10.1016/j.prp.2023.154807
R. Abdelhady, S. Saber, M.A. Abdel-Reheim, M.M.S. Alamri, J. Alfaifi, M.I. Adam, L.A. Saleh, A.I. Farag, E.A. Elmorsy, H.S. El-wakeel, Unveiling the therapeutic potential of exogenous β-hydroxybutyrate for chronic colitis in rats: Novel insights on autophagy, apoptosis, and pyroptosis, Frontiers in Pharmacology 14 1239025.
Abdelmaksoud, 2023, Mitochondrial remodeling in colorectal cancer initiation, progression, metastasis, and therapy: A review, Pathol. - Res. Pract., 246, 10.1016/j.prp.2023.154509
Ismail, 2019, Diagnostic significance of miR-639 and miR-10b in βreast cancer patients, Meta Gene, 19, 155, 10.1016/j.mgene.2018.11.006
Su, 2023, DA-SRN: Omics data analysis based on the sample network optimization for complex diseases, Comput. Biol. Med., 164, 10.1016/j.compbiomed.2023.107252
Minutti-Zanella, 2022, miRNAs in multiple sclerosis: a clinical approach, Mult. Scler. Relat. Disord., 63, 10.1016/j.msard.2022.103835
El-Husseiny, 2022, Smart/stimuli-responsive hydrogels: state-of-the-art platforms for bone tissue engineering, Appl. Mater. Today, 10.1016/j.apmt.2022.101560
El-Husseiny, 2023, Stimuli-responsive hydrogels: smart state of-the-art platforms for cardiac tissue engineering, Front Bioeng. Biotechnol., 11, 1174075, 10.3389/fbioe.2023.1174075
Al-Noshokaty, 2022, Selenium nanoparticles overcomes sorafenib resistance in thioacetamide induced hepatocellular carcinoma in rats by modulation of mTOR, NF-κB pathways and LncRNA-AF085935/GPC3 axis, J. Life Sci., 10.1016/j.lfs.2022.120675
Rizk, 2022, Exosomal-long non-coding RNAs journey in colorectal cancer: Evil and goodness faces of key players, Life Sci., 292, 10.1016/j.lfs.2022.120325
Koch, 2013, Epigenetics and miRNAs in the diagnosis and treatment of multiple sclerosis, Trends Mol. Med., 19, 23, 10.1016/j.molmed.2012.10.008
Guerau-de-Arellano, 2010, miRNAs in multiple sclerosis: regulating the regulators, J. Neuroimmunol., 229, 3, 10.1016/j.jneuroim.2010.08.025
Gao, 2021, MicroRNA in multiple sclerosis, Clin. Chim. Acta, 516, 92, 10.1016/j.cca.2021.01.020
Ridolfi, 2013, Expression and genetic analysis of microRNAs involved in multiple sclerosis, Int. J. Mol. Sci., 14, 4375, 10.3390/ijms14034375
Chen, 2016, The role of microRNAs in the pathogenesis of autoimmune diseases, Autoimmun. Rev., 15, 1171, 10.1016/j.autrev.2016.09.003
Fenoglio, 2016, Effect of fingolimod treatment on circulating miR-15b, miR23a and miR-223 levels in patients with multiple sclerosis, J. Neuroimmunol., 299, 81, 10.1016/j.jneuroim.2016.08.017
Ma, 2014, Expression, regulation and function of microRNAs in multiple sclerosis, Int. J. Med. Sci., 11, 810, 10.7150/ijms.8647
Ghadiri, 2018, Analysis of the expression of mir-34a, mir-199a, mir-30c and mir-19a in peripheral blood CD4+ T lymphocytes of relapsing-remitting multiple sclerosis patients, Gene, 659, 109, 10.1016/j.gene.2018.03.035
Bergman, 2016, Circulating miR-150 in CSF is a novel candidate biomarker for multiple sclerosis, Neurol. -Neuroimmunol. Neuroinflamm., 3, 10.1212/NXI.0000000000000219
Jernås, 2013, MicroRNA regulate immune pathways in T-cells in multiple sclerosis (MS), BMC Immunol., 14, 1, 10.1186/1471-2172-14-32
Hoye, 2018, MicroRNA signature of central nervous system‐infiltrating dendritic cells in an animal model of multiple sclerosis, Immunology, 155, 112, 10.1111/imm.12934
Nowak, 2022, The role of non-coding RNAs in neuroinflammatory process in multiple sclerosis, Mol. Neurobiol., 59, 4651, 10.1007/s12035-022-02854-y
Wang, 2022, MicroRNAs as T lymphocyte regulators in multiple sclerosis, Front. Mol. Neurosci., 15
Fenoglio, 2013, Decreased circulating miRNA levels in patients with primary progressive multiple sclerosis, Mult. Scler. J., 19, 1938, 10.1177/1352458513485654
Salman, 2014, Protective effect of proanthocyanidins on nephrotoxicity induced by antitumor dose of cisplatin in ehrlich solid tumor-bearing mice, Arab. J. Lab. Med, 40, 953
Gonzalez-Martinez, 2023, Early miR-320b and miR-25-3p miRNA levels correlate with multiple sclerosis severity at 10 years: a cohort study, J. Neuroinflamm., 20, 1, 10.1186/s12974-023-02816-8
Rahimirad, 2021, Identification of hsa-miR-106a-5p as an impact agent on promotion of multiple sclerosis using multi-step data analysis, Neurol. Sci., 1
D'Ambrosio, 2015, Peripheral blood biomarkers in multiple sclerosis, Autoimmun. Rev., 14, 1097, 10.1016/j.autrev.2015.07.014
Lorenzi, 2012, miR-15a and 16-1 are downregulated in CD4+ T cells of multiple sclerosis relapsing patients, Int. J. Neurosci., 122, 466, 10.3109/00207454.2012.678444
Lindberg, 2010, Altered expression of miR‐17–5p in CD4+ lymphocytes of relapsing–remitting multiple sclerosis patients, Eur. J. Immunol., 40, 888, 10.1002/eji.200940032
Gandhi, 2013, Circulating microRNAs as biomarkers for disease staging in multiple sclerosis, Ann. Neurol., 73, 729, 10.1002/ana.23880
Saeidi, 2023, Dysregulation of miR-193a serves as a potential contributor to MS pathogenesis via affecting RhoA and Rock1, Mult. Scler. Relat. Disord., 69, 10.1016/j.msard.2022.104468
Martinez, 2020, MicroRNAs as disease progression biomarkers and therapeutic targets in experimental autoimmune encephalomyelitis model of multiple sclerosis, Neural Regen. Res., 15, 1831, 10.4103/1673-5374.280307
Fenoglio, 2012, MicroRNAs as active players in the pathogenesis of multiple sclerosis, Int. J. Mol. Sci., 13, 13227, 10.3390/ijms131013227
Pröbstel, 2015, B cells and autoantibodies in multiple sclerosis, Int. J. Mol. Sci., 16, 16576, 10.3390/ijms160716576
Dolati, 2018, Dysregulated network of miRNAs involved in the pathogenesis of multiple sclerosis, Biomed. Pharmacother., 104, 280, 10.1016/j.biopha.2018.05.050
Miyazaki, 2014, Junior, V.D. Dang, A novel microRNA-132-surtuin-1 axis underlies aberrant B-cell cytokine regulation in patients with relapsing-remitting multiple sclerosis, Plos One, 9, 10.1371/journal.pone.0105421
Siegel, 2012, Circulating microRNAs involved in multiple sclerosis, Mol. Biol. Rep., 39, 6219, 10.1007/s11033-011-1441-7
Huang, 2016, MicroRNAs associated with the pathogenesis of multiple sclerosis, J. Neuroimmunol., 295, 148, 10.1016/j.jneuroim.2016.04.014
Salou, 2015, Involvement of CD8+ T cells in multiple sclerosis, Front. Immunol., 6, 604, 10.3389/fimmu.2015.00604
Arruda, 2015, Autologous hematopoietic SCT normalizes miR-16,-155 and-142-3p expression in multiple sclerosis patients, Bone Marrow Transplant., 50, 380, 10.1038/bmt.2014.277
Fani Maleki, 2019, Innate immune cells: monocytes, monocyte-derived macrophages and microglia as therapeutic targets for Alzheimer’s disease and multiple sclerosis, Front. Cell. Neurosci., 13, 10.3389/fncel.2019.00355
Mishra, 2012, Kinetics of proinflammatory monocytes in a model of multiple sclerosis and its perturbation by laquinimod, Am. J. Pathol., 181, 642, 10.1016/j.ajpath.2012.05.011
Cugurra, 2021, Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma, Sci. (N. Y., N. Y. ), 373, 10.1126/science.abf7844
Akaishi, 2018, Peripheral blood monocyte count at onset may affect the prognosis in multiple sclerosis, J. Neuroimmunol., 319, 37, 10.1016/j.jneuroim.2018.03.016
Makhlouf, 2001, Increased percentage of IL-12+ monocytes in the blood correlates with the presence of active MRI lesions in MS, J. Neuroimmunol., 119, 145, 10.1016/S0165-5728(01)00371-X
Locatelli, 2018, Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model, Nat. Neurosci., 21, 1196, 10.1038/s41593-018-0212-3
Giladi, 2020, Cxcl10+ monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation, Nat. Immunol., 21, 525, 10.1038/s41590-020-0661-1
King, 2009, Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease, Blood, 113, 3190, 10.1182/blood-2008-07-168575
Galli, 2019, GM-CSF and CXCR4 define a T helper cell signature in multiple sclerosis, Nat. Med., 25, 1290, 10.1038/s41591-019-0521-4
Lotfi, 2020, Evaluation of the effect of GM-CSF blocking on the phenotype and function of human monocytes, Sci. Rep., 10, 1567, 10.1038/s41598-020-58131-2
Lee, 2020, GM-CSF: A Promising Target in Inflammation and Autoimmunity, ImmunoTargets Ther., 9, 225, 10.2147/ITT.S262566
Huang, 2018, Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion, Nat. Neurosci., 21, 530, 10.1038/s41593-018-0090-8
Jiang, 2014, Macrophages: A double-edged sword in experimental autoimmune encephalomyelitis, Immunol. Lett., 160, 17, 10.1016/j.imlet.2014.03.006
Rawji, 2013, The Benefits and Detriments of Macrophages/Microglia in Models of Multiple Sclerosis, Clin. Dev. Immunol., 2013, 10.1155/2013/948976
Distéfano-Gagné, 2023, Roles and regulation of microglia activity in multiple sclerosis: insights from animal models, Nat. Rev. Neurosci., 24, 397, 10.1038/s41583-023-00709-6
Auffray, 2009, Blood monocytes: development, heterogeneity, and relationship with dendritic cells, Annu. Rev. Immunol., 27, 669, 10.1146/annurev.immunol.021908.132557
Mishra, 2016, Myeloid cells — targets of medication in multiple sclerosis, Nat. Rev. Neurol., 12, 539, 10.1038/nrneurol.2016.110
Matsumoto, 1998, Role of natural killer cells and TCRγ δ T cells in acute autoimmune encephalomyelitis, Eur. J. Immunol., 28, 1681, 10.1002/(SICI)1521-4141(199805)28:05<1681::AID-IMMU1681>3.0.CO;2-T
Huang, 2006, The neuronal chemokine CX3CL1/fractalkine selectively recruits NK cells that modify experimental autoimmune encephalomyelitis within the central nervous system, FASEB J., 20, 896, 10.1096/fj.05-5465com
Xu, 2005, Mechanism of natural killer (NK) cell regulatory role in experimental autoimmune encephalomyelitis, J. Neuroimmunol., 163, 24, 10.1016/j.jneuroim.2005.02.011
Hertwig, 2016, CX3CR1-dependent recruitment of mature NK cells into the central nervous system contributes to control autoimmune neuroinflammation, Eur. J. Immunol., 46, 1984, 10.1002/eji.201546194
Galazka, 2007, EAE Tolerance Induction with Hsp70-Peptide Complexes Depends on H60 and NKG2D Activity1, J. Immunol., 179, 4503, 10.4049/jimmunol.179.7.4503
Vivier, 2008, Functions of natural killer cells, Nat. Immunol., 9, 503, 10.1038/ni1582
Rodríguez-Martín, 2015, Natural killer cell subsets in cerebrospinal fluid of patients with multiple sclerosis, Clin. Exp. Immunol., 180, 243, 10.1111/cei.12580
Han, 2014, Comprehensive immunophenotyping of cerebrospinal fluid cells in patients with neuroimmunological diseases, J. Immunol. (Baltim., Md.: 1950), 192, 2551, 10.4049/jimmunol.1302884
Caruana, 2017, Natural killer cell subpopulations are associated with MRI activity in a relapsing-remitting multiple sclerosis patient cohort from Australia, Mult. Scler., 23, 1479, 10.1177/1352458516679267
Plantone, 2013, Circulating CD56dim NK cells expressing perforin are increased in progressive multiple sclerosis, J. Neuroimmunol., 265, 124, 10.1016/j.jneuroim.2013.10.004
Romero-Suárez, 2019, The central nervous system contains ILC1s that differ from NK Cells in the response to inflammation, Front. Immunol., 10, 10.3389/fimmu.2019.02337
Kwong, 2017, T-bet-dependent NKp46(+) innate lymphoid cells regulate the onset of T(H)17-induced neuroinflammation, Nat. Immunol., 18, 1117, 10.1038/ni.3816
Hirose, 2020, Type 2 innate lymphoid cells induce CNS demyelination in an HSV-IL-2 mouse model of multiple sclerosis, iScience, 23, 10.1016/j.isci.2020.101549
Russi, 2015, Cutting Edge: c-Kit signaling differentially regulates type 2 innate lymphoid cell accumulation and susceptibility to central nervous system demyelination in male and female SJL Mice, J. Immunol., 194, 5609, 10.4049/jimmunol.1500068
Russi, 2018, Male-specific IL-33 expression regulates sex-dimorphic EAE susceptibility, Proc. Natl. Acad. Sci. USA, 115, E1520, 10.1073/pnas.1710401115
Eken, 2019, Fingolimod alters tissue distribution and cytokine production of human and murine innate lymphoid cells, Front. Immunol., 10, 10.3389/fimmu.2019.00217
Mair, 2014, Thy1+ Sca1+ innate lymphoid cells infiltrate the CNS during autoimmune inflammation, but do not contribute to disease development, Eur. J. Immunol., 44, 37, 10.1002/eji.201343653
Hatfield, 2015, Group 3 innate lymphoid cells accumulate and exhibit disease-induced activation in the meninges in EAE, Cell. Immunol., 297, 69, 10.1016/j.cellimm.2015.06.006
Degn, 2015, Increased prevalence of lymphoid tissue inducer cells in the cerebrospinal fluid of patients with early multiple sclerosis, Mult. Scler. J., 22, 1013, 10.1177/1352458515609795
Perry, 2012, Inhibition of LTi Cell Development by CD25 Blockade Is Associated with Decreased Intrathecal Inflammation in Multiple Sclerosis, Sci. Transl. Med., 4, 145ra106, 10.1126/scitranslmed.3004140
Serafini, 2016, RORγt expression and lymphoid neogenesis in the brain of patients with secondary progressive multiple sclerosis, J. Neuropathol. Exp. Neurol., 75, 877, 10.1093/jnen/nlw063
Attfield, 2022, The immunology of multiple sclerosis, Nat. Rev. Immunol., 22, 734, 10.1038/s41577-022-00718-z
Haas, 2016, Myeloid dendritic cells exhibit defects in activation and function in patients with multiple sclerosis, J. Neuroimmunol., 301, 53, 10.1016/j.jneuroim.2016.10.007
Thewissen, 2014, Circulating dendritic cells of multiple sclerosis patients are proinflammatory and their frequency is correlated with MS-associated genetic risk factors, Mult. Scler., 20, 548, 10.1177/1352458513505352
Krumbholz, 2007, CCL19 is constitutively expressed in the CNS, up-regulated in neuroinflammation, active and also inactive multiple sclerosis lesions, J. Neuroimmunol., 190, 72, 10.1016/j.jneuroim.2007.07.024
Karni, 2006, Innate immunity in multiple sclerosis: myeloid dendritic cells in secondary progressive multiple sclerosis are activated and drive a proinflammatory immune response, J. Immunol. (Baltim., Md.: 1950), 177, 4196, 10.4049/jimmunol.177.6.4196
Ko, 2014, GM-CSF–Responsive monocyte-derived dendritic cells are pivotal in Th17 pathogenesis, J. Immunol., 192, 2202, 10.4049/jimmunol.1302040
Segal, 2008, Repeated subcutaneous injections of IL12/23 P40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study, Lancet Neurol., 7, 796, 10.1016/S1474-4422(08)70173-X
Schwab, 2010, An imbalance of two functionally and phenotypically different subsets of plasmacytoid dendritic cells characterizes the dysfunctional immune regulation in multiple sclerosis, J. Immunol. (Baltim., Md.: 1950), 184, 5368, 10.4049/jimmunol.0903662
Younger, 2023, Multiple sclerosis: Motor dysfunction, Handb. Clin. Neurol., 196, 119, 10.1016/B978-0-323-98817-9.00016-8
Luessi, 2012, Neurodegeneration in multiple sclerosis: novel treatment strategies, Expert Rev. Neurother., 12, 1061, 10.1586/ern.12.59
Oh, 2018, Mult. Scler.: Clin. Asp., 31, 752
Kattimani, 2018, Dysregulation NRXN1 Mutant MIR8485 leads Calcium overload pre-Synap. inducing Neurodegener. Mult. Scler., 22, 153
Pietrasik, 2021, Circulating miRNAs as potential biomarkers distinguishing relapsing–remitting from secondary progressive multiple sclerosis, A Rev., 22, 11887
Barca-Mayo, 2012, Fine-Tuning oligodendrocyte Dev. Micro, 6, 13
Sofroniew, 2010, Astrocytes: biology and pathology, Acta Neuropathol., 119, 7, 10.1007/s00401-009-0619-8
Kim, 2019, The role of astrocytes in the central nervous system focused on BK channel and heme oxygenase metabolites: a review, Antioxidants, 8, 121, 10.3390/antiox8050121
Hayakawa, 2016, Transfer of mitochondria from astrocytes to neurons after stroke, Nature, 535, 551, 10.1038/nature18928
Takano, 2009, Astrocytes and ischemic injury, Stroke, 40, S8, 10.1161/STROKEAHA.108.533166
Eroglu, 2010, Regulation of synaptic connectivity by glia, Nature, 468, 223, 10.1038/nature09612
Sofroniew, 2009, Molecular dissection of reactive astrogliosis and glial scar formation, Trends Neurosci., 32, 638, 10.1016/j.tins.2009.08.002
Abbott, 2006, Astrocyte-endothelial interactions at the blood-brain barrier, Nat. Rev. Neurosci., 7, 41, 10.1038/nrn1824
Bramow, 2010, Demyelination versus remyelination in progressive multiple sclerosis, Brain, 133, 2983, 10.1093/brain/awq250
Elkady, 2016, Matrix metalloproteinase (MMP)-2–1306 C> T gene polymorphism affects circulating levels of MMP-2 in Egyptian asthmatic patients, Gene Rep., 5, 57, 10.1016/j.genrep.2016.09.001
El-Husseiny, 2023, Impact of adipose tissue depot harvesting site on the multilineage induction capacity of male rat adipose-derived mesenchymal stem cells: an in vitro study, Int. J. Mol. Sci., 24, 7513, 10.3390/ijms24087513
Rossi, 2009, Astrocytic dysfunction: Insights on the role in neurodegeneration, Brain Res. Bull., 80, 224, 10.1016/j.brainresbull.2009.07.012
Farina, 2007, Astrocytes are active players in cerebral innate immunity, Trends Immunol., 28, 138, 10.1016/j.it.2007.01.005
El-Ashmawy, 2022, Carnosine and crocin ameliorate oxidative stress in rats with rhabdomyolysis-induced acute kidney injury through upregulating HO-1 gene expression, Food, Bioscience, 49
Maciak, 2021, miR-155 as an important regulator of multiple sclerosis pathogenesis. A review, Int. J. Mol. Sci., 22, 4332, 10.3390/ijms22094332
Taganov, 2006, NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses, Proc. Natl. Acad. Sci., 103, 12481, 10.1073/pnas.0605298103
Bai, 2022, MicroRNA-21 is a versatile regulator and potential treatment target in central nervous system disorders, Front. Mol. Neurosci., 15, 10.3389/fnmol.2022.842288
Duffy, 2020, The role of MicroRNAs in repair processes in multiple sclerosis, Cells, 9, 1711, 10.3390/cells9071711
Colonna, 2017, Microglia function in the central nervous system during health and neurodegeneration, Annu. Rev. Immunol., 35, 441, 10.1146/annurev-immunol-051116-052358
Hickman, 2018, Microglia in neurodegeneration, Nat. Neurosci., 21, 1359, 10.1038/s41593-018-0242-x
Yong, 2022, Microglia in multiple sclerosis: Protectors turn destroyers, Neuron, 110, 3534, 10.1016/j.neuron.2022.06.023
Scarisbrick, 2002, Activity of a newly identified serine protease in CNS demyelination, Brain, 125, 1283, 10.1093/brain/awf142
Kauppinen, 2005, Poly (ADP-ribose) polymerase-1 promotes microglial activation, proliferation, and matrix metalloproteinase-9-mediated neuron death, J. Immunol., 174, 2288, 10.4049/jimmunol.174.4.2288
Merson, 2010, Role of cytokines as mediators and regulators of microglial activity in inflammatory demyelination of the CNS, Neuromolecular Med., 12, 99, 10.1007/s12017-010-8112-z
Haider, 2011, Oxidative damage in multiple sclerosis lesions, Brain, 134, 1914, 10.1093/brain/awr128
Lloyd, 2019, The pro-remyelination properties of microglia in the central nervous system, Nat. Rev. Neurol., 15, 447, 10.1038/s41582-019-0184-2
Sherafat, 2021, Microglial neuropilin-1 promotes oligodendrocyte expansion during development and remyelination by trans-activating platelet-derived growth factor receptor, Nat. Commun., 12, 2265, 10.1038/s41467-021-22532-2
Cardoso, 2012, de Lima, miR‐155 modulates microglia‐mediated immune response by down‐regulating SOCS‐1 and promoting cytokine and nitric oxide production, Immunology, 135, 73, 10.1111/j.1365-2567.2011.03514.x
Mandolesi, 2017, miR-142-3p is a key regulator of IL-1β-dependent synaptopathy in neuroinflammation, J. Neurosci.: Off. J. Soc. Neurosci., 37, 546, 10.1523/JNEUROSCI.0851-16.2016
Yu, 2017, MiR-124 contributes to M2 polarization of microglia and confers brain inflammatory protection via the C/EBP-α pathway in intracerebral hemorrhage, Immunol. Lett., 182, 1, 10.1016/j.imlet.2016.12.003
Taganov, 2006, NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses, Proc. Natl. Acad. Sci. USA, 103, 12481, 10.1073/pnas.0605298103
Zhou, 2016, Downregulation of miR-199b promotes the acute spinal cord injury through IKKβ-NF-κB signaling pathway activating microglial cells, Exp. Cell Res., 349, 60, 10.1016/j.yexcr.2016.09.020
Bradl, 2010, Oligodendrocytes: biology and pathology, Acta Neuropathol., 119, 37, 10.1007/s00401-009-0601-5
Dutta, 2007, Pathogenesis of axonal and neuronal damage in multiple sclerosis, Neurology, 68, S22, 10.1212/01.wnl.0000275229.13012.32
Dulamea, 2017, Role of oligodendrocyte dysfunction in demyelination, remyelination and neurodegeneration in multiple sclerosis, Adv. Exp. Med. Biol., 958, 91, 10.1007/978-3-319-47861-6_7
Keirstead, 1999, The role of oligodendrocytes and oligodendrocyte progenitors in CNS remyelination, Adv. Exp. Med. Biol., 468, 183, 10.1007/978-1-4615-4685-6_15
Philips, 2017, Oligodendroglia: metabolic supporters of neurons, J. Clin. Investig., 127, 3271, 10.1172/JCI90610
Zhao, 2010, MicroRNA-mediated control of oligodendrocyte differentiation, Neuron, 65, 612, 10.1016/j.neuron.2010.02.018
Wang, 2017, miR-219 cooperates with miR-338 in myelination and promotes myelin repair in the CNS, Dev. Cell, 40, 566, 10.1016/j.devcel.2017.03.001
Safari, 2023, MicroRNAs and their implications in CD4+ T-cells, oligodendrocytes and dendritic cells in multiple sclerosis pathogenesis, Curr. Mol. Med., 23, 630, 10.2174/1566524022666220525150259
Abolghasemi, 2023, MicroRNAs expression in peripheral blood mononuclear cells of patients with multiple sclerosis propose, Mol. Biol. Rep., 50, 167, 10.1007/s11033-022-07905-0
Majd, 2018, MiR-9-5p and miR-106a-5p dysregulated in CD4+ T-cells of multiple sclerosis patients and targeted essential factors of T helper17/regulatory T-cells differentiation, Iran. J. Basic Med. Sci., 21, 277
Lecca, 2016, MiR-125a-3p timely inhibits oligodendroglial maturation and is pathologically up-regulated in human multiple sclerosis, Sci. Rep., 6, 34503, 10.1038/srep34503
Giunti, 2021, Role of miRNAs shuttled by mesenchymal stem cell-derived small extracellular vesicles in modulating neuroinflammation, Sci. Rep., 11, 1740, 10.1038/s41598-021-81039-4
Sartorius, 2020, The multiple roles of hepatitis B virus X protein (HBx) dysregulated microRNA in hepatitis B virus-associated hepatocellular carcinoma (HBV-HCC) and immune pathways, Viruses, 12, 746, 10.3390/v12070746
Putnam, 2023, Modulating the immune system as a therapeutic target for myelodysplastic syndromes and acute myeloid leukemia, Biochem. Cell Biol. (ja), 10.1139/bcb-2022-0374
Läderach, 2022, Altered immune response to the epstein–barr virus as a prerequisite for multiple sclerosis, Cells, 11, 2757, 10.3390/cells11172757
Ma, 2020, Identifying lncRNA–miRNA–mRNA networks to investigate Alzheimer’s disease pathogenesis and therapy strategy, Aging (Albany NY), 12, 2897, 10.18632/aging.102785
Yang, 2020, MicroRNAs in acute pancreatitis: from pathogenesis to novel diagnosis and therapy, J. Cell. Physiol., 235, 1948, 10.1002/jcp.29212
Fresegna, 2020, Re-examining the role of TNF in MS pathogenesis and therapy, Cells, 9, 2290, 10.3390/cells9102290
Sartorius, 2020, The multiple roles of hepatitis B Virus X Protein (HBx) dysregulated microRNA in hepatitis b virus-associated hepatocellular carcinoma (HBV-HCC) and immune pathways, Virus, 12
Putnam, 2023, Modulating the immune system as a therapeutic target for myelodysplastic syndromes and acute myeloid leukemia, Biochem Cell Biol., 10.1139/bcb-2022-0374
Basu, 2021, Differentiation and regulation of TH cells: a balancing act for cancer immunotherapy, Front. Immunol., 12, 10.3389/fimmu.2021.669474
Heng, 2022, Chemokine-driven migration of pro-inflammatory CD4+ T Cells in CNS autoimmune disease, Front. Immunol., 13, 10.3389/fimmu.2022.817473
Abdulla, 2021, Ahr ligands differentially regulate Mirna-132 which targets Hmgb1 and to control the differentiation of Tregs and Th-17 cells during delayed-type hypersensitivity response, Front. Immunol., 12, 10.3389/fimmu.2021.635903
Woodruff, 2022, Dysregulated naive B cells and de novo autoreactivity in severe COVID-19, Nature, 611, 139, 10.1038/s41586-022-05273-0
Rijnink, 2021, B-cells and antibodies as contributors to effector immune responses in tuberculosis, Front. Immunol., 12, 10.3389/fimmu.2021.640168
Rodgers, 2022, AB‐cell or a key player? The different roles of B‐cells and antibodies in melanoma, Pigment Cell Melanoma Res., 35, 303, 10.1111/pcmr.13031
Jafarzadeh, 2021, Dysregulated expression of miRNAs in immune thrombocytopenia, Epigenomics, 13, 1317, 10.2217/epi-2021-0092
Maiti, 2022, Increased miR150 expression in tumors enhances lymphocytes infiltration causing immunosuppression through inflammatory chemokines, Cancer Res., 82, 5827, 10.1158/1538-7445.AM2022-5827
Weidner, 2021, Spotlight on microRNAs in allergy and asthma, Allergy, 76, 1661, 10.1111/all.14646
Saldanha, 2020, Tissue damage in human cutaneous leishmaniasis: correlations between inflammatory cells and molecule expression, Front. Cell. Infect. Microbiol., 10, 355, 10.3389/fcimb.2020.00355
Lin, 2022, Astragalus mongholicus Bunge and Panax notoginseng formula (A&P) improves renal mesangial cell damage in diabetic nephropathy by inhibiting the inflammatory response of infiltrated macrophages, BMC Complement. Med. Ther., 22, 17, 10.1186/s12906-021-03477-x
Longo, 2021, 2, 2’4, 4’-tetrabromodiphenyl ether (pbde-47) modulates the intracellular mirna profile, sev biogenesis and their mirna cargo exacerbating the lps-induced pro-inflammatory response in thp-1 macrophages, Front. Immunol., 12, 10.3389/fimmu.2021.664534
Miron, 2011, Cells of the oligodendroglial lineage, myelination, and remyelination, Biochim. Et. Biophys. Acta (BBA)-Mol. Basis Dis., 1812, 184, 10.1016/j.bbadis.2010.09.010
Dugas, 2010, Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination, Neuron, 65, 597, 10.1016/j.neuron.2010.01.027
Zhang, 2017, MiR-146a promotes remyelination in a cuprizone model of demyelinating injury, Neuroscience, 348, 252, 10.1016/j.neuroscience.2017.02.029
Chen, 2018, Dysregulated microRNA involvement in multiple sclerosis by induction of T helper 17 cell differentiation, Front. Immunol., 9, 1256, 10.3389/fimmu.2018.01256
Liu, 2017, MicroRNA-15b suppresses Th17 differentiation and is associated with pathogenesis of multiple sclerosis by targeting O-GlcNAc transferase, J. Immunol., 198, 2626, 10.4049/jimmunol.1601727
McCormack, 2013, Natalizumab: a review of its use in the management of relapsing-remitting multiple sclerosis, Drugs, 73, 1463, 10.1007/s40265-013-0102-7
Meira, 2014, Unraveling natalizumab effects on deregulated miR-17 expression in CD4+ T cells of patients with relapsing-remitting multiple sclerosis, J. Immunol. Res.
Ingwersen, 2015, Natalizumab restores aberrant mi RNA expression profile in multiple sclerosis and reveals a critical role for miR‐20b, Ann. Clin. Transl. Neurol., 2, 43, 10.1002/acn3.152
Sievers, 2012, Altered microRNA expression in B lymphocytes in multiple sclerosis: towards a better understanding of treatment effects, Clin. Immunol., 144, 70, 10.1016/j.clim.2012.04.002
Meira, 2014, MiR-126: a novel route for natalizumab action?, Mult. Scler. J., 20, 1363, 10.1177/1352458514524998
Muñoz-Culla, 2014, Blood miRNA expression pattern is a possible risk marker for natalizumab-associated progressive multifocal leukoencephalopathy in multiple sclerosis patients, Mult. Scler. J., 20, 1851, 10.1177/1352458514534513
Kremenchutzky, 2007, The safety and efficacy of IFN-β products for the treatment of multiple sclerosis, Expert Opin. Drug Saf., 6, 279, 10.1517/14740338.6.3.279
Hecker, 2013, MicroRNA expression changes during interferon-beta treatment in the peripheral blood of multiple sclerosis patients, Int. J. Mol. Sci., 14, 16087, 10.3390/ijms140816087
De Felice, 2014, Small non-coding RNA signature in multiple sclerosis patients after treatment with interferon-β, BMC Med. Genom., 7, 1, 10.1186/1755-8794-7-26
Aharony, 2016, Multiple sclerosis (MS) for the urologist: What should urologists know about MS?, Neurourol. Urodyn., 35, 174, 10.1002/nau.22713
Waschbisch, 2011, Glatiramer acetate treatment normalizes deregulated microRNA expression in relapsing remitting multiple sclerosis, PloS One, 6, 10.1371/journal.pone.0024604
Minutti-Zanella, 2022, miRNAs in multiple sclerosis: A clinical approach, Mult. Scler. Relat. Disord., 63, 10.1016/j.msard.2022.103835
Gandhi, 2015, miRNA in multiple sclerosis: search for novel biomarkers, Mult. Scler. J., 21, 1095, 10.1177/1352458515578771
Regev, 2016, Comprehensive evaluation of serum microRNAs as biomarkers in multiple sclerosis, Neurol. -Neuroimmunol. Neuroinflamm., 3, 10.1212/NXI.0000000000000267
Aung, 2015, MMP-9 expression is increased in B lymphocytes during multiple sclerosis exacerbation and is regulated by microRNA-320a, J. Neuroimmunol., 278, 185, 10.1016/j.jneuroim.2014.11.004
Oh, 2011, Genomic loss of miR-486 regulates tumor progression and the OLFM4 antiapoptotic factor in gastric cancer, Clin. Cancer Res., 17, 2657, 10.1158/1078-0432.CCR-10-3152
Haghikia, 2012, Regulated microRNAs in the CSF of patients with multiple sclerosis, A case-Control Study, 79, 2166
Ahlbrecht, 2016, Deregulation of microRNA-181c in cerebrospinal fluid of patients with clinically isolated syndrome is associated with early conversion to relapsing–remitting multiple sclerosis, Mult. Scler. J., 22, 1202, 10.1177/1352458515613641
Shademan, 2020, Investigation of the miRNA146a and miRNA155 gene expression levels in patients with multiple sclerosis, J. Clin. Neurosci., 78, 189, 10.1016/j.jocn.2020.04.071
Søndergaard, 2013, Differential microRNA expression in blood in multiple sclerosis, Mult. Scler. J., 19, 1849, 10.1177/1352458513490542
Dong, 2014, MicroRNA dysregulation as a prognostic biomarker in colorectal cancer, Cancer Manag. Res., 405
Negoi, 2017, MicroRNA-21 as a prognostic biomarker in patients with pancreatic cancer–a systematic review and meta-analysis, Am. J. Surg., 214, 515, 10.1016/j.amjsurg.2017.03.049
Moghadam, 2020, Analysis of MicroRNA-18a Expression in Multiple Sclerosis Patients, Rep. Biochem. Mol. Biol., 8, 429
Montoya, 2017, A distinct inhibitory function for miR-18a in Th17 cell differentiation, J. Immunol., 199, 559, 10.4049/jimmunol.1700170
Regev, 2018, Identification of MS-specific serum miRNAs in an international multicenter study, Neurol. -Neuroimmunol. Neuroinflamm., 5, 10.1212/NXI.0000000000000491
Du, 2012, miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers, PloS One, 7, 10.1371/journal.pone.0039167
Shimonaka, 2003, Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow, J. Cell Biol., 161, 417, 10.1083/jcb.200301133
Engelhardt, 2008, Natalizumab: targeting α4-integrins in multiple sclerosis, NDD, 5, 16
Banerjee, 2011, Recent advances in the pathobiology of Hodgkin's lymphoma: potential impact on diagnostic, predictive, and therapeutic strategies, Adv. Hematol., 2011, 10.1155/2011/439456
Zhang, 2010, Human tyrosine hydroxylase natural genetic variation: delineation of functional transcriptional control motifs disrupted in the proximal promoter, Circ.: Cardiovasc. Genet., 3, 187
Lin, 2006, Coordination of NF-κB and NFAT antagonism by the forkhead transcription factor Foxd1, J. Immunol., 176, 4793, 10.4049/jimmunol.176.8.4793
Vistbakka, 2017, Circulating microRNAs as biomarkers in progressive multiple sclerosis, Mult. Scler. J., 23, 403, 10.1177/1352458516651141
Sataer, 2023, Exosomal microRNAs as diagnostic biomarkers and therapeutic applications in neurodegenerative diseases, Neurol. Res., 45, 191, 10.1080/01616412.2022.2129768
Gentile, 2022, Dysregulated miRNAs as biomarkers and therapeutical targets in neurodegenerative diseases, J. Pers. Med., 12, 770, 10.3390/jpm12050770
N.N. Saeidi, A. Dabiri, R. Mansouri, A. Moomivand, M. Goudarzvand, miRNAs as Valuable Diagnostic Biomarkers in Patients with Multiple Sclerosis, Journal ISSN 2766 (2023) 2276.
Omarova, 2022, Free circulating miRNA as a potential diagnostic marker in multiple sclerosis, Neurol., Neuropsychiatry, Psychosom., 14, 29, 10.14412/2074-2711-2022-1S-29-33
Dillenseger, 2021, Digital biomarkers in multiple sclerosis, Brain Sci., 11, 1519, 10.3390/brainsci11111519
Yang, 2022, MicroRNAs (miRNAs): Novel potential therapeutic targets in colorectal cancer, Front. Oncol., 12, 1054846, 10.3389/fonc.2022.1054846
Wang, 2022, Integrated analysis of differentially expressed genes and a ceRNA network to identify hub lncRNAs and potential drugs for multiple sclerosis, Am. J. Transl. Res., 14, 772
Walsh, 2021, miRNAs in microglia: Important players in multiple sclerosis pathology, ASN neuro, 13, 10.1177/1759091420981182
Chmielewska, 2023, Targeting CD20 in multiple sclerosis—review of current treatment strategies, Neurol. i Neurochir. Pol., 10.5603/PJNNS.a2023.0022
Abdolahi, 2022, A review of molecular interplay between neurotrophins and miRNAs in neuropsychological disorders, Mol. Neurobiol., 59, 6260, 10.1007/s12035-022-02966-5
Comi, 2021, Role of B cells in multiple sclerosis and related disorders, Ann. Neurol., 89, 13, 10.1002/ana.25927
Shah, 2023, A Bibliogr. Mult. Scler. Lesions Detect. Methods Using Brain MRIs, arXiv Prepr. arXiv, 2302, 09516
Schumann, 2022, Detection of fall risk in multiple sclerosis by gait analysis—an innovative approach using feature selection ensemble and machine learning algorithms, Brain Sci., 12, 1477, 10.3390/brainsci12111477
York, 2022, Magnetisation transfer, diffusion and g-ratio measures of demyelination and neurodegeneration in early relapsing-remitting multiple sclerosis: a longitudinal microstructural MRI study, medRxiv