The role of lipid peroxidation and antioxidants in oxidative modification of LDL
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Gofman, 1950, The role of lipids and lipoproteins in atherosclerosis, Science, 111, 166, 10.1126/science.111.2877.166
Bailey, 1973, Regulation of cell cholesterol content, 63
Geer, 1961, The fine structure of human atherosclerotic lesions, Am. J. Pathol., 38, 263
Adams, 1975, Phagocytes, lipid-removal and regression of atheroma, J. Pathol., 116, 225, 10.1002/path.1711160406
Schaffner, 1980, Arterial foam cells with distinctive immunomorphologic and histochemical features of macrophages, Am. J. Pathol., 100, 57
Gerrity, 1981, The role of the monocyte in atherogenesis. I. Transition of blood-borne monocytes into foam cells in fatty lesions, Am. J. Pathol., 103, 181
Gerrity, 1981, The role of the monocyte in atherogenesis. II. Migration of foam cells from atherosclerotic lesions, Am. J. Pathol., 103, 191
Cookson, 1971, The origin of foam cells in atherosclerosis, Br. J. Exp. Pathol., 52, 62
Goldstein, 1977, The low-density lipoprotein pathway and its relation to atherosclerosis, Ann. Rev. Biochem., 46, 897, 10.1146/annurev.bi.46.070177.004341
Goldstein, 1979, Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition, 76, 33
Windaus, 1910, Über den Gehalt normaler und atheromatoser Aorten an Cholesterin und Cholesterinestern, Hoppe—Seyler's Z. Physiol. Chem., 67, 174, 10.1515/bchm2.1910.67.2.174
Ross, 1976, The pathogenesis of atherosclerosis (part I), N. Eng. J. Med., 95, 369, 10.1056/NEJM197608122950707
Fogelman, 1980, Malondialdehyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages, 77, 2214
Henriksen, 1981, Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: Recognition by receptors for acetylated low density lipoproteins, 78, 6499
Harland, 1973, Lipids of human atheroma. VIII. Oxidised dervatives of cholesteryl linoleate, Biochim. Biophys. Acta, 316, 378, 10.1016/0005-2760(73)90076-3
Schuh, 1978, Oxygen-mediated heterogenicity of apo-low-density lipoprotein, 75, 3173
Brown, 1983, Lipoprotein metabolism in the macrophage: Implications for cholesterol deposition in atherosclerosis, Ann. Rev. Biochem., 52, 223, 10.1146/annurev.bi.52.070183.001255
Morel, 1983, Cytotoxicity of low density lipoprotein oxidised by cell-generated free radicals, J. Cell Biol., 97, 427a
Morel, 1983, Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipid, J. Lipid Res., 24, 1070, 10.1016/S0022-2275(20)37921-9
Heinecke, 1984, Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture, J. Clin. Invest., 4, 1890, 10.1172/JCI111609
Morel, 1984, Endothelial and smooth muscle cells alter low density lipoprotein in vitro by free radical oxidation, Arteriosclerosis, 4, 357, 10.1161/01.ATV.4.4.357
Steinbrecher, 1984, Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids, 81, 3883
Cathcart, 1985, Monocytes and neutrophils oxidize low density lipoprotein making it cytotoxic, J. Leukocyte Biol., 38, 341, 10.1002/jlb.38.2.341
Parthasarathy, 1985, Essential role of phospholipase A2 activity in endothelial cell-induced modification of low density lipoprotein, 82, 3000
Heinecke, 1986, Superoxide-mediated modification of low density lipoprotein by arterial smooth muscle cells, J. Clin. Invest., 77, 757, 10.1172/JCI112371
Parthasarathy, 1986, Macrophage oxidation of low density lipoprotein generates a modified form recognized by the scavenger receptor, Arteriosclerosis, 6, 505, 10.1161/01.ATV.6.5.505
VanHinsbergh, 1986, Role of endothelial cells and their products in the modification of low-density lipoproteins, Biochim. Biophys. Acta, 878, 49, 10.1016/0005-2760(86)90343-7
Esterbauer, 1987, Autoxidation of hman low density lipoprotein: loss of polyunsaturated fatty acids and vitamin E and generation of aldehydes, J. Lipid Res., 28, 495, 10.1016/S0022-2275(20)38678-8
Parthasarathy, 1987, Oxidation of low-density lipoprotein by thiol compounds leads to its recognition by the acetyl LDL receptor, Biochim. Biophys. Acta, 917, 337, 10.1016/0005-2760(87)90139-1
Nishigaki, 1984, Effect of linoleic acid hydroperoxide on uptake of low density lipoprotein by cultured smooth muscle cells from rabbit aorta, Biochem. Int., 8, 501
Avogaro, 1988, Presence of a modified low density lipoprotein in humans, Arteriosclerosis, 8, 79, 10.1161/01.ATV.8.1.79
Glavind, 1952, Studies on the role of lipoperoxides in human pathology. II. The presence of peroxidized lipids in the atherosclerotic aorta, Acta Pathol. Microbiol. Scand., 30, 1, 10.1111/j.1699-0463.1952.tb00157.x
Sparrow, 1988, Enzymatic modification of low density lipoprotein by purified lipoxygenase plus phospholipase A2 mimics cell-mediated oxidative modification, J. Lipid Res., 29, 745, 10.1016/S0022-2275(20)38493-5
Steinbrecher, 1988, Role of superoxide in endothelial-cell modification of low-density lipoproteins, Biochim. Biophys. Acta, 959, 20, 10.1016/0005-2760(88)90145-2
Arai, 1989, Multiple receptors for modified low density lipoproteins in mouse peritoneal macrophages: Different uptake mechanisms for acetylated and oxidized low density lipoproteins, Biochem. Biophys. Res. Commun., 159, 1375, 10.1016/0006-291X(89)92262-6
Boyd, 1989, Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit, Am. J. Pathol., 135, 815
Cathcart, 1989, Superoxide anion participation in human monocyte-mediated oxidation of low-density lipoprotein and conversion of low-density lipoprotein to a cytotoxin, J. Immunol., 142, 1963, 10.4049/jimmunol.142.6.1963
Hoff, 1989, Modification of LDL with 4-hydroxynonenal, a propagation product of lipid peroxidation, induces uptake of LDL by macrophages, Arteriosclerosis, 9, 538, 10.1161/01.ATV.9.4.538
Esterbauer, 1989, Vitamin E and other lipophilic antioxidants protect LDL against oxidation, Fat Sci. Technol., 91, 316
Bedwell, 1989, The action of defined oxygen-centred free radicals on human low-density lipoprotein, Biochem. J., 262, 707, 10.1042/bj2620707
Harats, 1989, Cigarette smoking renders LDL susceptible to peroxidative modification and enhanced metabolism by macrophages, Atherosclerosis, 79, 245, 10.1016/0021-9150(89)90130-5
Palinski, 1989, Low density lipoprotein undergoes oxidative modification in vivo, 86, 1372
Parthasarathy, 1989, A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein, 86, 1046
Sparrow, 1989, A macrophage receptor that recognize oxidized low density lipoprotein but not acetylated low density lipoprotein, J. Biol. Chem., 264, 2599, 10.1016/S0021-9258(19)81655-1
Steinbrecher, 1989, Recognition of oxidized low density lipoprotein by the scavenger receptor of macrophages results from derivatization of apolipoprotein B by products of fatty acid peroxidation, J. Biol. Chem., 264, 15216, 10.1016/S0021-9258(19)84812-3
Hennig, 1988, Lipid peroxidation and endothelial cell injury: Implications in atherosclerosis. Review, Free Rad. Biol. Med., 4, 99, 10.1016/0891-5849(88)90070-6
Gey, 1987, Plasma levels of antioxidant vitamins in relation to ischemic heart diseases and cancer, Am. J. Clin. Nutr., 45, 1368, 10.1093/ajcn/45.5.1368
Jürgens, 1990, Detection of new epitopes formed upon oxidation of low-density lipoprotein, lipoprotein (a) and very-low-density lipoprotein, Biochem. J., 265, 605, 10.1042/bj2650605
Kalyanaraman, 1990, Oxidation of low-density lipoprotein by Cu++ and lipoxygenase — An electron spin resonance study, Biochim. Biophys. Acta, 1035, 286, 10.1016/0304-4165(90)90090-J
Palinski, 1990, Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein, Arteriosclerosis, 10, 325, 10.1161/01.ATV.10.3.325
Rohrer, 1990, Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II, Nature, 343, 570, 10.1038/343570a0
Ylä-Herttuala, 1990, Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions, 87, 6959
Salonen, 1992, Autoantibody against oxidised LDL and progression of carotid atherosclerosis, Lancet, 339, 883, 10.1016/0140-6736(92)90926-T
Van Berkel, 1991, Different fate in vivo of oxidatively modified low density lipoprotein and acetylated low density lipoprotein in rats, J. Biol. Chem., 266, 2282, 10.1016/S0021-9258(18)52241-9
Jürgens, 1987, Modification of human serum low density lipoprotein by oxidation-characterization and pathophysiological implications, Chem. Phys. Lipids, 45, 315, 10.1016/0009-3084(87)90070-3
Steinberg, 1989, Beyond cholesterol. Modifications of low-density lipoprotein that increases its atherogenicity, N. Eng. J. Med., 320, 915
Esterbauer, 1990, Biochemical, structural and functional properties of oxidized low-density lipoprotein, Chemical Res. Toxicol., 3, 77, 10.1021/tx00014a001
Steinbrecher, 1990, Role of oxidatively modified LDL in atherosclerosis, Free Rad. Biol. Med., 9, 155, 10.1016/0891-5849(90)90119-4
Lang, 1990, Oxidized LDL and atherosclerosis, 266
Bruckdorfer, 1990, Free radicals, lipid peroxidation and atherosclerosis, Curr. Op. Lipidol., 1, 529, 10.1097/00041433-199012000-00008
Gebicki, 1991, Oxidation of low-density lipoprotein in vitro, 371
Myant, 1990, Cholesterol metabolism, LDL and the LDL receptor, 99
European Atherosclerosis Society, 1987, Strategies for the prevention of coronary heart disease: A policy statement of the European Atherosclerosis Society, Eur. Heart J., 8, 77
Hobbs, 1990, The LDL receptor locus in familial hypercholesterolemia: Mutational analysis of a membrane protein, Ann. Rev. Genet., 24, 133, 10.1146/annurev.ge.24.120190.001025
Watanabe, 1980, Serial inbreeding of rabbits with hereditary hyperlipidemia (WHHL-rabbit). Incidence and development of atherosclerosis and xanthoma, Atherosclerosis, 36, 261, 10.1016/0021-9150(80)90234-8
Ylä-Herttuala, 1988, Characterization of two lipoproteins containing apolipoproteins B and E from lesion-free human aortic intima, J. Lipid Res., 29, 563, 10.1016/S0022-2275(20)38503-5
Hoff, 1982, Isolation, purification and characterization of a lipoprotein containing apo B from the human aorta, Atherosclerosis, 42, 273, 10.1016/0021-9150(82)90157-5
Sattler, 1991, Oxidation of lipoprotein Lp(a). A comparison with low-density lipoproteins, Biochim. Biophys. Acta, 1081, 65, 10.1016/0005-2760(91)90251-C
Laggner, 1981, Neutron small angle scattering on selectively deuterated human plasma low density lipoproteins, J. Biol. Chem., 256, 11832, 10.1016/S0021-9258(19)68481-4
Steinbrecher, 1987, Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL, Arteriosclerosis, 7, 135, 10.1161/01.ATV.7.2.135
Barenghi, 1990, NMR analysis of low-density lipoprotein oxidatively-modified in vitro, Free Rad. Res. Comm., 8, 175, 10.3109/10715769009087991
Yang, 1987, The complete structure of human apolipoprotein B-100 and its messenger RNA, 77
Arshad, 1991, Plasma lipoprotein peroxidation potential: A test to evaluate individual susceptibility to peroxidation, Clin. Chem., 37, 1756, 10.1093/clinchem/37.10.1756
Esterbauer, 1989, Continous monitoring of in vitro oxidation of human low density lipoprotein, Free Rad. Res. Comm., 6, 67, 10.3109/10715768909073429
Knipping, 1990, Antioxidants and resistance against oxidation of porcine LDL subfractions, J. Lipid Res., 31, 1965, 10.1016/S0022-2275(20)42260-6
El-Saadani, 1989, A spectrophotometric assay for lipid peroxides in serum lipoproteins using a commercially available reagent, J. Lipid Res., 30, 627, 10.1016/S0022-2275(20)38354-1
Jürgens, 1988, LDL modified by endogenous lipid peroxidation products, 13
Jessup, 1990, α-Tocopherol consumption during low-density lipoprotein oxidation, Biochem. J., 265, 399, 10.1042/bj2650399
Jessup, 1990, The role of oxidative metabolism and antioxidants in low-density lipoprotein structure and metabolism, 239
Stocker, 1991, Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol, 88, 1646
Lenz, 1990, Lipid hydroperoxy and hydroxy derivatives in copper-catalyzed oxidation of low density lipoprotein, J. Lipid Res., 31, 1043, 10.1016/S0022-2275(20)42744-0
Esterbauer, 1990, Endogenous antioxidants and lipoprotein oxidation, Biochem. Soc. Transact., 18, 1059, 10.1042/bst0181059
Dieber-Rotheneder, 1991, Effect of oral supplementation with d-alpha-tocopherol on the vitamin E content of human low density lipoproteins and resistance to oxidation, J. Lipid Res., 32, 1325, 10.1016/S0022-2275(20)41962-5
Esterbauer, 1991, Effect of antioxidants on oxidative modification of LDL, Annals Med., 23, 573, 10.3109/07853899109150520
Esterbauer, 1988, Effect of peroxidative conditions on human plasma low-density lipoproteins, 203
Striegl, 1989, Investigation of lipid peroxidation in human low density lipoprotein
Babiy, 1990, Vitamin E content and low density lipoprotein oxidizability induced by free radicals, Atherosclerosis, 81, 175, 10.1016/0021-9150(90)90064-P
Parthasarathy, 1990, Low density lipoprotein rich in oleic acid is protected against oxidative modification: Implications for dietary prevention of atherosclerosis, 87, 3894
Halliwell, 1990, How to characterize a biological antioxidant, Free Rad. Res. Comm., 9, 1, 10.3109/10715769009148569
Massay, 1984, Kinetics of transfer of α-tocopherol between model and native plasma lipoproteins, Biochim. Biophys. Acta, 793, 387, 10.1016/0005-2760(84)90253-4
Thellman, 1985, In vitro uptake of [3H] α-tocopherol from low density lipoprotein by cultured human fibroblasts, J. Nutr., 115, 1673, 10.1093/jn/115.12.1673
DiMascio, 1989, Lycopene as the most efficient singlet oxygen quencher, Arch. Biochem. Biophys., 274, 532, 10.1016/0003-9861(89)90467-0
Ray, 1954, Experiments on the degradation of lipoproteins from serum, J. Phys. Chem., 58, 841, 10.1021/j150520a010
Lee, 1980, Malondialdehyde formation in stored plasma, Biochem. Biophys. Res. Commun., 95, 1633, 10.1016/S0006-291X(80)80090-8
Esterbauer, 1988, Oxidation of human low density lipoprotein with special attention to aldehydic lipid peroxidation products, 243
Cornwell, 1990, Paradoxical effects of vitamin E: Oxidized lipoproteins, prostanoids and the pathogenesis of atherosclerosis, 215
Satoh, 1978, Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method, Clin. Chim. Acta, 90, 37, 10.1016/0009-8981(78)90081-5
Szczeklik, 1980, Low density lipoproteins (LDL) are carriers for lipid peroxides and inhibit prostacyclin (PGI2) biosynthesis in arteries, Artery, 7, 488
Goto, 1982, Lipid peroxides as a cause of vascular disease, 295
Aznar, 1983, Serum malondialdehyde-like material (MDA-LM) in acute myocardial infarction, J. Clin. Pathol., 36, 712, 10.1136/jcp.36.6.712
Hagihara, 1984, Age-dependent changes in lipid peroxide levels in the lipoprotein fractions of human serum, J. Gerontology, 39, 269, 10.1093/geronj/39.3.269
Ledwozyw, 1986, The relationship between plasma triglycerides, cholesterol, total lipids and lipid peroxidation products during human atherosclerosis, Clin. Chim. Acta, 155, 275, 10.1016/0009-8981(86)90247-0
Schimke, 1986, Konzentration Thiobarbitursäure-reaktiver Substanzen (TBARS) im Serum nach Myokardinfarkt, Klin. Wochenschr., 64, 1237, 10.1007/BF01734466
Stringer, 1989, Lipid peroxides and atherosclerosis, Br. J. Med., 298, 281, 10.1136/bmj.298.6669.281
Yalcin, 1989, Increased plasma and erythrocyte lipid peroxidation in hyperlipidemic individuals, Atherosclerosis, 80, 169, 10.1016/0021-9150(89)90025-7
Nishigaki, 1981, Lipid peroxide levels of serum lipoprotein fractions of diabetic patients, Biochem. Med., 25, 373, 10.1016/0006-2944(81)90096-X
Maseki, 1981, Lipid peroxide levels and lipid content of serum lipoprotein fractions of pregnant subjects with or without pre-eclampsia, Clin. Chim. Acta, 115, 155, 10.1016/0009-8981(81)90071-1
Domagala, 1989, Incides of lipid peroxidation in patients with hypercholesterolemia and hypertriglyceridemia, Wiener klinische Wochenschrift, 101, 425
Miyzawa, 1989, Determination of phospholipid hydroperoxides in human blood plasma by a chemiluminescence-HPLC assay, Free Rad. Biol. Med., 7, 209, 10.1016/0891-5849(89)90017-8
van Kuijk, 1986, Occurrence of 4-hydroxyalkenals in rat tissues determined as pentafluorobenzyl oxime derivatives by gas chromatography-mass spectrometry, Biochem. Biophys. Res. Commun., 139, 144, 10.1016/S0006-291X(86)80091-2
Steinbrecher, 1987, Oxidation of human low density lipoprotein results in derivatisation of lysine residues of apolipoprotein B by lipid peroxide decomposition products, J. Biol. Chem., 262, 3603, 10.1016/S0021-9258(18)61395-X
Quehenberger, 1987, Investigation of lipid peroxidation in human low density lipoprotein, Free Rad. Res. Comm., 3, 233, 10.3109/10715768709069788
Koller, 1986, Investigation of human plasma low density lipoprotein by three-dimensional fluorescence spectroscopy, FEBS Lett., 198, 229, 10.1016/0014-5793(86)80411-2
Dobretsov, 1983, Spatial organization of low-density lipoproteins of the human aorta (a fluorescent probe study), Byull. Eksp. Biol. Med., 96, 45, 10.1007/BF00837921
Avogaro, 1989, Isolation and partial characterization of an oxidized LDL in humans, Basic Life Sciences, 40, 391
Cazzolato, 1991, Characterization of a more electronegatively charged LDL subfraction by ion exchange HPLC, Free Rad. Biol. Med., 11, 247, 10.1016/0891-5849(91)90120-R
Jürgens, 1986, Modification of human low density lipoprotein by the lipid peroxidation product 4-hydroxynonenal, Biochim. Biophys. Acta, 875, 103, 10.1016/0005-2760(86)90016-0
Bittolo Bon, 1983, Changes of apolipoprotein B molecular weight and immunoreactivity in malondialdehyde-modified low density lipoproteins, Artery, 12, 74
Shimano, 1991, Oxidation-labile subfraction of human plasma low density lipoprotein isolated by ion-exchange chromatography, J. Lipid Res., 32, 763, 10.1016/S0022-2275(20)42028-0
Parums, 1990, Serum antibodies to oxidized low-density lipoprotein and ceroid in chronic periaortitis, Arch. Pathol. Lab. Med., 114, 383
Orekhov, 1991, Autoantibodies against modified low density lipoprotein. Nonlipid factor of blood plasma that stimulates foam cell formation, Arteriosclerosis and Thrombosis, 11, 316, 10.1161/01.ATV.11.2.316
Mondon, 1987, Presence of acetyl-like modified LDL in human placental blood, Med. Sci. Res., 15, 385
Piotrowski, 1990, Evidence for lipid peroxidation in atherosclerosis, Life Sci., 46, 715, 10.1016/0024-3205(90)90077-5
Kanazawa, 1987, Comparison among lipid constituents in native LDL, ultra-water-soluble LDL and vessel wall, and their significance in arteriosclerosis, Exper. Mol. Pathol., 47, 166, 10.1016/0014-4800(87)90071-2
Camejo, 1985, Properties of lipoprotein complexes isolated by affinity chromatography from human aorta, Biomed. Biochim. Acta, 44, 389
Shaikh, 1988, Modified plasma-derived lipoproteins in human atherosclerotic plaques, Atherosclerosis, 69, 165, 10.1016/0021-9150(88)90011-1
Daugherty, 1988, Isolation of low density lipoprotein from atherosclerotic vascular tissue of Watanabe heritable hyperlipidemic rabbits, Arteriosclerosis, 8, 768, 10.1161/01.ATV.8.6.768
Hong, 1984, Comparison of apoprotein B of low density lipoproteins of human interstitial fluid and plasma, Biochem. J., 222, 49, 10.1042/bj2220049
Smith, 1985, Plasma lipid peroxidation in hyperlipidemic chickens, Atherosclerosis, 57, 119, 10.1016/0021-9150(85)90143-1
Smith, 1988, Plasma lipid peroxidation and atherosclerosis in restricted ovulator chickens, Basic Life Sci., 49, 941
Morel, 1989, Antioxidant treatment of diabetic rats inhibits lipoprotein oxidation and cytotoxicity, J. Lipid Res., 30, 1827, 10.1016/S0022-2275(20)38196-7
Gonen, 1987, Immunogenicity of malondialdehyde-modified low density lipoproteins, Atherosclerosis, 65, 265, 10.1016/0021-9150(87)90042-6
Salmon, 1987, Immunological detection of low-density lipoproteins modified by malondialdehyde in vitro or in vivo, Biochim. Biophys. Acta, 920, 215, 10.1016/0005-2760(87)90097-X
Haberland, 1988, Malondialdehyde-altered protein occurs in atheroma of Watanabe heritable hyperlipidemic rabbits, Science, 241, 215, 10.1126/science.2455346
Rosenfeld, 1990, Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits, Arteriosclerosis, 10, 336, 10.1161/01.ATV.10.3.336
Mowri, 1988, Monoclonal DLR1a/104G antibody recognizing peroxidized lipoproteins in atherosclerotic lesions, Biochim. Biophys. Acta, 963, 208, 10.1016/0005-2760(88)90282-2
Esterbauer, 1991, Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes, Free Rad. Biol. Med., 11, 81, 10.1016/0891-5849(91)90192-6
Rosenfeld, 1991, Macrophage-derived foam cells freshly isolated from rabbit atherosclerotic lesions degrade modified lipoproteins, promote oxidation of low-density lipoprotein, and contain oxidation-specific lipid-protein adducts, J. Clin. Invest., 87, 90, 10.1172/JCI115006
Zawadzki, 1989, An immunochemical marker of low density lipoprotein oxidation, J. Lipid Res., 30, 885, 10.1016/S0022-2275(20)38305-X
Ross, 1986, The pathogenesis of atherosclerosis—an update, N. Eng. J. Med., 314, 488, 10.1056/NEJM198602203140806
Pitas, 1990, Expression of the acetyl low density lipoprotein receptor by rabbit fibroblasts and smooth muscle cells, J. Biol. Chem., 265, 12722, 10.1016/S0021-9258(19)38404-2
Kodama, 1990, Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils, Nature, 343, 531, 10.1038/343531a0
Jialal, 1990, Physiologic levels of ascorbate inhibit the oxidative modification of low density lipoprotein, Atherosclerosis, 82, 185, 10.1016/0021-9150(90)90039-L
Mahley, 1979, Altered metabolism (in vivo and in vitro) of plasma lipoproteins after selective chemical modification of lysine residues of the apoproteins, J. Clin. Invest., 64, 743, 10.1172/JCI109518
Haberland, 1984, Role of lysines in mediating interaction of modified low density lipoproteins with the scavenger receptor of human monocyte macrophages, J. Biol. Chem., 259, 11305, 10.1016/S0021-9258(18)90863-X
Gonen, 1983, The interaction of carbamylated low-density lipoprotein with cultured cells. Studies with human fibroblasts, rat peritoneal macrophages and human monocyte-derived macrophages, Biochim. Biophys. Acta, 754, 201, 10.1016/0005-2760(83)90162-5
Haberland, 1985, Scavenger receptor-mediated recognition of maleyl bovine plasma albumin and the demaleylated protein in human monocyte macrophages, 82, 2693
Haberland, 1982, Specificity of receptor-mediated recognition of malondialdehyde-modified low density lipoprotein, 79, 1712
Jessup, 1986, The interaction of 4-hydroxynonenal-modified low density lipoproteins with the fibroblast apoB/E receptor, Biochem. J., 234, 245, 10.1042/bj2340245
Hoff, 1988, Low density lipoproteins (LDL) modified simultaneously with 4-hydroxynonenal and malondialdehyde—a model for oxidized LDL, Arteriosclerosis, 8, 551a
Parthasarathy, 1987, Recognition of solubilized apoproteins from delipidated, oxidized low density lipoprotein (LDL) by the acetyl-LDL receptor, 84, 537
Heinecke, 1987, Free radical modification of low-density lipoprotein: Mechanism and biological consequences, Free Rad. Biol. Med., 3, 65, 10.1016/0891-5849(87)90040-2
Hiramatsu, 1987, Superoxide initiates oxidation of low density lipoprotein by human monocytes, Arteriosclerosis, 7, 55, 10.1161/01.ATV.7.1.55
Cathcart, 1988, Oxidative modification of low density lipoprotein by activated human monocytes and the cell line U937 and HL 60, In Vitro, 24, 1001
Leake, 1990, The oxidative modification of low density lipoproteins by macrophages, Biochem. J., 270, 741, 10.1042/bj2700741
Horrigan, 1991, Oxidation of β-very low density lipoprotein by endothelial cells enhances its metabolism by smooth muscle cells in culture, Arteriosclerosis and Thrombosis, 11, 279, 10.1161/01.ATV.11.2.279
Jürgens, 1990, Modified serum lipoproteins and atherosclerosis, Ann. Rep. Med. Chem., 25, 169
Cramer, 1991, Iodometric measurement of lipid hydroperoxides in human plasma, Anal. Biochem., 193, 204, 10.1016/0003-2697(91)90010-Q
Slater, 1972
Reyftmann, 1990, Sensitivity of tryptophan and related compounds to oxidation induced by lipid autoperoxidation. Application to human serum low- and high-density lipoproteins, Biochim. Biophys. Acta, 1042, 159, 10.1016/0005-2760(90)90002-F
Bedwell, 1987, Effects of oxygen-centred free radicals on low density lipoprotein structure and metabolism, Biochem. Soc. Trans., 15, 259, 10.1042/bst0150259
Esterbauer, 1991, Role of vitamin E in preventing the oxidation of low-density lipoprotein, Am. J. Clin. Nutr., 53, 314S, 10.1093/ajcn/53.1.314S
Esterbauer, 1989, The role of vitamin E and carotenoids in preventing oxidation of low density lipoproteins, Ann. NY Acad. Sci., 570, 254, 10.1111/j.1749-6632.1989.tb14925.x
Esterbauer, 1992, The role of vitamin E in lipoprotein oxidation, 649
Esterbauer, 1992, Oxidative modification of lipoproteins in artherosclerosis
Jessup, 1991, 5-Lipoxygenase is not essential in macrophage-mediated oxidation of low density lipoprotein, Biochem. J., 278, 163, 10.1042/bj2780163
Steinbrecher, 1990, Role of low density lipoprotein oxidation in foam cell formation, 193
Niki, 1987, Antioxidants in relation to lipid peroxidation, Chem. Phys. Lipids, 44, 227, 10.1016/0009-3084(87)90052-1
Esterbauer, 1989, Aldehydes formed by lipid peroxidation: Mechanism of formation, occurrence and determination, 239
Hoff, 1988, Chemical and functional changes in LDL following modification by 4-hydroxynonenal, 459
Brnjas-Kraljevic, 1991, EPR evidence for the oxidation-induced formation of negatively charged species on the low-density lipoprotein surface, Free Rad. Res. Comm., 14, 307, 10.3109/10715769109093420
Stadtman, 1989, Oxygen radical-mediated damage of enzymes: Biological implications, 11
Fong, 1987, Nonenzymatic oxidative cleavage of peptide bonds in apoprotein B 100, J. Lipid Res., 28, 1466, 10.1016/S0022-2275(20)38576-X
Waeg, 1990, Untersuchungen zur Fragmentierung von Apolipoprotein B bei der Oxidation von Low Density Lipoprotein
Chan, 1987, Autoxidation of unsaturated lipids, 1
Evensen, 1983, LDL-induced cytotoxicity and its inhibition by antioxidant treatment in cultured human endothelial cells and fibroblasts, Arteriosclerosis, 49, 23, 10.1016/0021-9150(83)90004-7
Parthasarathy, 1986, Probucol inhibits oxidative modification of low density lipoprotein, J. Clin. Invest., 7, 641, 10.1172/JCI112349
Minotti, 1987, The role of iron in the initiation of lipid peroxidation, Chem. Phys. Lipids, 44, 191, 10.1016/0009-3084(87)90050-8
Kitagawa, 1989, Effects of elevated d-alpha(RRR)-to-copherol dosage in man, J. Nutr. Sci. Vitaminol., 35, 133, 10.3177/jnsv.35.133
Farrell, 1975, Megavitamin E supplementation in man, Am. J. Clin. Nutr., 28, 1381, 10.1093/ajcn/28.12.1381
Sato, 1990, Free radical-mediated chain oxidation of low density lipoprotein and its synergistic inhibition by vitamin E and vitamin C, Arch. Biochem. Biophys., 279, 402, 10.1016/0003-9861(90)90508-V
Huber, 1990, 17 beta estradiol inhibits LDL oxidation and cholesteryl ester formation in cultured macrophages, Free Rad. Res. Comm., 8, 167, 10.3109/10715769009087990
Gey, 1989, Plasma vitamins E and A inversely related to mortality from ischemic heart disease in cross-cultural epidemiology, Ann. NY Acad. Sci., 570, 268, 10.1111/j.1749-6632.1989.tb14926.x
Gey, 1991, Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in cross-cultural epidemiology, Am. J. Clin. Nutr., 53, 326B, 10.1093/ajcn/53.1.326S
Riemersma, 1991, Risk of angina pectoris and plasma concentrations of vitamins A, C and E and carotene, Lancet, 337, 1, 10.1016/0140-6736(91)93327-6
Boscoboinik, 1991, α-tocopherol (vitamin E) regulates vascular smooth muscle cell proliferation and protein kinase C activity, Arch. Biochem. Biophys., 286, 264, 10.1016/0003-9861(91)90039-L
Boscoboinik, 1991, Inhibition of cell proliferation by α-tocopherol, J. Biol. Chem., 266, 6188, 10.1016/S0021-9258(18)38102-X
Tolonen, 1988, Antioxidant supplementation decreases TBA reactants in serum of elderly, Biol. Trace Element Res., 17, 221, 10.1007/BF02795458
Salonen, 1991, Interactions of serum copper, selecnium, and low density lipoprotein cholesterol in atherogenesis, Br. Med. J., 302, 756, 10.1136/bmj.302.6779.756
Gaziano, 1990, Beta carotene for chronic stable angina, Circulation, 82, 202
Verlangieri, 1992, Effects of d-alpha-Tocopherol supplementation on experimentally induce primate atherosclerosis, J. Am. Coll. Nutr., 11, 131, 10.1080/07315724.1992.12098234
Inagaki, 1978, A douple-blind controlled study of the efficacy of dl-α-tocopheryl nicotinate in patients with vascular disease, 338
Gillilan, 1977, Quantitative evaluation of vitamin E in the treatment of angina pectoris, Am. Heart J., 93, 444, 10.1016/S0002-8703(77)80406-7
Anderson, 1974, A double-blind trial of vitamin E in angina pectoris, Am. J. Clin. Nutr., 27, 1174, 10.1093/ajcn/27.8.1174
Verlangieri, 1990, Prevention and regression of primate atherosclerosis by d-alpha-tocopherol, Free Rad. Biol. Med., 9, 73, 10.1016/0891-5849(90)90427-K
Wilson, 1978, Vitamin E antioxidants and lipid peroxidation in experimental atherosclerosis of rabbits, J. Nutr., 108, 1858, 10.1093/jn/108.11.1858
Weitzel, 1956, Lipid-soluble vitamins and atherosclerosis, Hoppe Seylers Z. Physiol. Chem., 304, 247, 10.1515/bchm2.1956.304.1-2.247
Nelson, 1980, Pathology of vitamin E deficiency, 397
Liu, 1984, Cardiomyopathy associated with vitamin E deficiency in seven gelada baboons, J. Am. Vet. Med. Assoc., 185, 1347
Chisolm, 1988, Lipoprotein oxidation and cytotoxicity: Effect of probucol on streptozotocin-treated rats, Am. J. Cardiol., 62, 20B, 10.1016/S0002-9149(88)80046-8
Godfried, 1989, Potentiation of atherosclerotic lesions in rabbits by a high dietary level of vitamin E, Br. J. Nutr., 61, 607, 10.1079/BJN19890148
Drake, 1969, Effect of [4,4′-(isopropylidenedithio)bis(2,6-di-t-butyl-phenol) on serum lipids and lipoproteins in human subjects, Metabolism, 18, 916, 10.1016/0026-0495(69)90032-8
Barnhart, 1970, Hypocholesterolemic effect of [4,4′-(isopropylidenedithio)bis(2,6-di-t-butylphenol)] (probucol), Am. J. Clin. Nutr., 23, 1229, 10.1093/ajcn/23.9.1229
Schwartz, 1988, Introduction—the probucol experience: A review of the past and a look at the future, Am. J. Cardiol., 62, 1B, 10.1016/S0002-9149(88)80043-2
Naruszewicz, 1984, A novel mechanism by which probucol lowers low density lipoprotein levels demonstrated in the LDL receptor-deficient rabbit, J. Lipid Res., 25, 1206, 10.1016/S0022-2275(20)34464-3
Parthasarathy, 1986, Probucol inhibits oxidative modification of low density lipoprotein, J. Clin. Invest., 77, 641, 10.1172/JCI112349
Kita, 1987, Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia, 84, 5928
Kita, 1988, Prevention of atherosclerotic progression in Watanabe rabbits by probucol, Am. J. Cardiol., 62, 13B, 10.1016/S0002-9149(88)80045-6
Carew, 1987, Antiatherogenic effect of probucal unrelated to its hypocholesterolemic effect: Evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit, 84, 7725
Nagano, 1989, Probucol does not affect lipoprotein metabolism in macrophages of Watanabe heritable hyperlipidemic rabbits, Arteriosclerosis, 9, 453, 10.1161/01.ATV.9.4.453
McLean, 1989, Effect of Probucol on the physical properties of low-density lipoproteins oxidized by copper, Biochemistry, 28, 321, 10.1021/bi00427a043
McLean, 1990, Antioxidant activity of probucol and its effects on phase transitions in phosphatidylcholine liposomes, Biochim. Biophys. Acta, 1029, 161, 10.1016/0005-2736(90)90449-X
Jialal, 1991, Varying susceptibility of different low density lipoproteins to oxidative modification, Arteriosclerosis and Thrombosis, 11, 482, 10.1161/01.ATV.11.3.482
Carpenter, 1990, Oxidation of cholesteryl linoleate by human monocyte-macrophages in vitro, Atherosclerosis, 83, 217, 10.1016/0021-9150(90)90167-H
Barnhart, 1989, Concentration-dependent antioxidant activity of probucol in low density lipoproteins in vitro: Probucol degradation precedes lipoprotein oxidation, J. Lipid Res., 30, 1703, 10.1016/S0022-2275(20)38219-5
Mino, 1989, Nutritional assessment of vitamin E in oxidative stress, Ann. NY Acad. Sci., 570, 296, 10.1111/j.1749-6632.1989.tb14929.x
Smith, 1989, Effect of dietary vitamin E on plasma lipids and atherogeneses in restricted ovulatory chickens, Atherosclerosis, 75, 105, 10.1016/0021-9150(89)90166-4
Finckh, 1991, Antiatherosclerotic effect of probucol in WHHL rabbits: Are there plasma parameters to evaluate this effect?, Eur. J. Clin. Pharmacol., 49, 577
Mao, 1991, Antioxidant activity of probucol and its analogs in hypercholesterolemic Watanabe rabbits, J. Med. Chem., 34, 298, 10.1021/jm00105a046
Mao, 1991, Attenuation of atherosclerosis in a modified strain of hypercholesterolemic Watanabe rabbits using a probucol analog (MDL 29,311) that does not lower serum cholesterol, Arteriosclerosis and Thrombosis, 11, 1266, 10.1161/01.ATV.11.5.1266
Daugherty, 1989, Probucol attenuates the development of aortic atherosclerosis in cholesterolfed rabbits, Br. J. Pharmacol., 98, 612, 10.1111/j.1476-5381.1989.tb12635.x
Stein, 1989, Lack of effect of probucol on atheroma formation in cholesterol-fed rabbits kept at comparable cholesterol levels, Atherosclerosis, 75, 145, 10.1016/0021-9150(89)90171-8
Vance, 1990, Lipoproteins secreted by cultured rat hepatocytes contain the antioxidant 1-alk-1-enyl-2-acylglycerophosphoethanolamine, Biochim. Biophys. Acta, 1045, 128, 10.1016/0005-2760(90)90141-J
Burton, 1990, Vitamin E: Antioxidant activity, biokinetics, and bioavailability, Ann. Rev. Nutr., 10, 357, 10.1146/annurev.nu.10.070190.002041
Camejo, 1991, Modifications of low-density lipoprotein induced by arterial proteoglycans and chondroitin-6-sulfate, Biochim. Biophys. Acta, 1096, 253, 10.1016/0925-4439(91)90013-Y
Seifert, 1990, Isolation and characterization of a complement-activating lipid extracted from human atherosclerotic lesions, J. Exp. Med., 172, 547, 10.1084/jem.172.2.547
O'Brien, 1991, Probucol treatment affects the cellular composition but not anti-oxidized low density lipoprotein immunoreactivity of plaques from Watanabe Heritable Hyperlipidemic rabbits, Arteriosclerosis and Thrombosis, 11, 751, 10.1161/01.ATV.11.3.751
Zawadzki, 1991, Cu2+-mediated oxidation of dialyzed plasma: Effects on low and high density lipoproteins and cholesteryl ester transfer protein, J. Lipid Res., 32, 243, 10.1016/S0022-2275(20)42085-1
Zhang, 1990, Effects of oxidatively modified LDL on cholesterol esterification in cultured macrophages, J. Lipid Res., 31, 1361, 10.1016/S0022-2275(20)42607-0
Lougheed, 1991, Oxidized low density lipoprotein is resistant to cathepsins and accumulates within macrophages, J. Biol. Chem., 266, 14519, 10.1016/S0021-9258(18)98717-X
Jaakkola, 1990, Lipoprotein degradation and cholesterol esterification in primary cell cultures of rabbit atherosclerotic lesions, Am. J. Pathol., 137, 457
Klimov, 1985, Lipoprotein-antibody immune complexes: Their catabolism and role in foam cell formation, Atherosclerosis, 58, 1, 10.1016/0021-9150(85)90051-6
Griffith, 1988, Low-density lipoprotein metabolism by human macrophages activated with low-density lipoprotein immune complex: A possible mechanism of foam cell formation, J. Exp. Med., 168, 1041, 10.1084/jem.168.3.1041
Gisinger, 1991, Erythrocyte-bound low-density lipoprotein immune complexes lead to cholesteryl ester accumulation in human monocyte-derived macrophages, Clin. Immunol. Immunopathol., 59, 37, 10.1016/0090-1229(91)90080-T
Szondy, 1983, Free and complexed anti-lipoprotein antibodies in vascular disease, Atherosclerosis, 49, 69, 10.1016/0021-9150(83)90008-4
Szondy, 1985, Occurrence of anti-low-density lipoprotein antibodies and circulating immune complexes in aged subjects, Mech. Ageing Dev., 29, 117, 10.1016/0047-6374(85)90012-0
Tatzber, 1991, Elevated serum neopterin levels in atherosclerosis, Atherosclerosis, 89, 203, 10.1016/0021-9150(91)90061-7
Kuzuya, 1991, Oxidation of low-density lipoprotein by copper and iron in phosphate buffer, Biochim. Biophys. Acta, 1084, 198, 10.1016/0005-2760(91)90221-3
Dunford, 1987, Free radicals in iron-containing systems, Free Rad. Biol. Med., 3, 405, 10.1016/0891-5849(87)90019-0
Rowley, 1983, Superoxide-dependent and ascorbate-dependent formation of hydroxyl radicals in the presence of copper salts: A physiologically significant reaction?, Arch. Biochem. Biophys., 225, 279, 10.1016/0003-9861(83)90031-0
Halliwell, 1989, Current status review: Free radicals, reactive oxygen species and human disease: A critical evaluation with special reference to atherosclerosis, Br. J. Exp. Path., 70, 737
Yamashita, 1990, Where metals bind in proteins, 87, 5648
Hauser, 1979, Interactions of the polar groups of phospholipid bilayer membranes, Progr. Surface and Membrane Science, 13, 297, 10.1016/B978-1-4831-9993-1.50010-1
Fujii, 1991, Site-specific mechanisms of initiation by α-tocopherol of lipid peroxide-dependent lipid peroxide-dependent lipid peroxidation in charged micelles, Arch. Biochem. Biophys., 284, 120, 10.1016/0003-9861(91)90273-L
Vile, 1987, Iron binding to microgomes and liposomes in relation to lipid peroxidation, FEBS Lett., 215, 151, 10.1016/0014-5793(87)80131-X
Yamamoto, 1988, Interaction of α-tocopherol with iron: Antioxidant and prooxidant effects of α-tocopherol in the oxidation of lipids in aqueous dispersions in the presence of iron, Biochim. Biophys. Acta, 958, 19, 10.1016/0005-2760(88)90241-X
Samuni, 1983, On the cytotoxicity of vitamin C and metal ions. A site-specfic Fenton mechanism, Eur. J. Biochem., 137, 119, 10.1111/j.1432-1033.1983.tb07804.x
Thomas, 1991, Lipid hydroperoxide involvement in copper-dependent and independent oxidation of low density lipoproteins, J. Pharmacol. Exp. Ther., 256, 1182
Krilov, 1988, Electron spin resonance spin-trapping study of peroxidation of human low density lipoproteins, Can. J. Chem., 66, 1957, 10.1139/v88-315
Wang, 1991, Increased levels of monohydroxy metabolites of arachidonic acid and linoleic acid in LDL and aorta from atherosclerotic rabbits, Biochim. Biophys. Acta, 1084, 129, 10.1016/0005-2760(91)90211-Y
Belkner, 1991, The oxygenation of cholesterol esters by the reticulocyte lipoxygenase, FEBS Lett., 279, 110, 10.1016/0014-5793(91)80263-3
Cominacini, 1991, A simple test for predisposition to LDL oxidation based on the fluorescence development during copper-catalyzed oxidative modification, J. Lipid Res., 32, 349, 10.1016/S0022-2275(20)42095-4
Hunt, 1990, Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose, Diabetes, 39, 1420, 10.2337/diabetes.39.11.1420
Janero, 1990, Malondialdehyde and thiobarbituric acid-reactivity diagnostic indices of lipid peroxidation and peroxidative tissue injury, Free Rad. Biol. Med., 9, 515, 10.1016/0891-5849(90)90131-2
Rankin, 1991, Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophages, J. Lipid Res., 32, 449, 10.1016/S0022-2275(20)42068-1
Cathcart, 1991, Lipoxygenase-mediated transformation of human low density lipoprotein to an oxidized and cytotoxic complex, J. Lipid Res., 32, 63, 10.1016/S0022-2275(20)42244-8
Rosenfeld, 1990, Macrophages, endothelial cells, and lipoprotein oxidation in the pathogenesis of atherosclerosis, Toxicol. Pathol., 18, 560, 10.1177/019262339001804a06
Bhadra, 1991, Peroxidation of cholesterol moiety of low density lipoprotein in the presence of human endothelial cells or Cu++ ions: Identification of major products and their effects, Biochem. Biophys. Res. Commun., 176, 431, 10.1016/0006-291X(91)90942-Z
Chait, 1991, Increased oxidative susceptibility of LDL subfractions in subjects with atherogenic lipoprotein phenotype, Arteriosclerosis and Thrombosis, 11, 1425a
Ylä-Herttuala, 1991, Rabbit and human atherosclerotic lesions contain IgG that recognizeds MDA-LDL and copper-oxidized LDL, Asteriosclerosis and Thrombosis, 11, 1426a
Sakurai, 1991, Oxidative modification of glycated low density lipoprotein in the presence of iron, Biochem. Biophys. Res. Commun., 177, 433, 10.1016/0006-291X(91)92002-2
Panasenko, 1991, Free radical modification of lipoproteins and cholesterol accumulation in cells upon atherosclerosis, Free Rad. Biol. Med., 10, 137, 10.1016/0891-5849(91)90007-P
Quinn, 1987, Oxidatively modified low density lipoproteins: A potential role in recruitment and retention of monocyte/macrophages during atherogenesis, 84, 2995
Autio, 1990, Oxidized low-density lipoprotein is chemotactic for arterial smooth muscle cells in culture, FEBS Lett., 277, 247, 10.1016/0014-5793(90)80857-F
Schmidt, 1990, Activation of soluble guanylate cyclase by nitrova-sodilators is inhibited by oxidized low-density lipoprotein, Biochem. Biophys. Res. Commun., 172, 614, 10.1016/0006-291X(90)90718-3
Cushing, 1990, Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells, 87, 5134
Berliner, 1990, Minimally modified low density lipoprotein stimulates monocyte endothelial interactions, J. Clin. Invest., 85, 1260, 10.1172/JCI114562
Rajavashisth, 1990, Induction of endothelial cell expression of granulocyte and macrophage colony-stimulating factors by modified low-density lipoproteins, Nature, 344, 254, 10.1038/344254a0
Drake, 1991, Minimally oxidized low-density lipoprotein induces tissue factor expression in cultured human endothelial cells, Am. J. Pathol., 138, 601
Liao, 1991, Minimally modified low density lipoprotein is biologically active in vivo in mice, J. Clin. Invest., 87, 2253, 10.1172/JCI115261
Weis, 1991, Oxidized low-density lipoprotein increases cultured human endothelial cell tissue factor activity and reduces protein C activation, FASEB J., 5, 2459, 10.1096/fasebj.5.10.2065893
Malden, 1991, The influence of oxidatively modified low density lipoproteins on expression of platelet-derived growth factor by human monocyte-derived macrophages, J. Biol. Chem., 266, 13901, 10.1016/S0021-9258(18)92786-9
Lehr, 1991, Role of leukotrienes in leukocyte adhesion following systemic administration of oxidatively modified human low density lipoprotein in hamsters, J. Clin. Invest., 88, 9, 10.1172/JCI115309
Kuzuya, 1991, Lipid peroxide and transition metals are requored for the toxicity of oxidized low density lipoprotein to cultured endothelial cells, Biochim. Biophys. Acta, 1096, 155, 10.1016/0925-4439(91)90054-D
Kugiyama, 1988, Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density liporpoteins, Circulation, 80, II
Kugiyama, 1988, Oxidized LDL impairs endothelium-dependent relaxation, Circulation, 80, 279
Kugiyama, 1990, Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins, Nature, 344, 160, 10.1038/344160a0
Yokoyama, 1990, Lysophosphatidylcholine: Essential role in the inhibition of endothelium-dependent vasorelaxation by oxidized low density lipoprotein, Biochem. Biophys. Res. Commun., 168, 301, 10.1016/0006-291X(90)91708-Z
Jacobs, 1990, Native and oxidized low-density lipoprotein have different inhibitory effects on endothelium-derived relaxing factor in the rabbit aorta, Br. J. Pharmacol., 100, 21, 10.1111/j.1476-5381.1990.tb12045.x
Darley-Usmar, 1991, Treatment of macrophages with oxidized low-density lipoprotein increases their intracellular glutathione content, Biochem. J., 278, 429, 10.1042/bj2780429
Jeny, 1986, Study of peroxidation in human and experimental atheroma by measurements of plasma malondialdehyde, Presse Med., 15, 1131
Kosugi, 1987, Toxicity of oxidized LDL to cultured fibroblasts is selective for S phase of the cell cycle, J. Cell Physiol., 130, 311, 10.1002/jcp.1041300302
De Graaf, 1991, Enhanced susceptibility to in vitro oxidation of the dense low density lipoprotein subfraction in healthy subjects, Asteriosclerosis and Thrombosis, 11, 298, 10.1161/01.ATV.11.2.298
Breugnot, 1990, Phenothiazines inhibit copper and endothelial cell-induced peroxidation of low density lipoprotein, Biochem. Pharmacol., 40, 1975, 10.1016/0006-2952(90)90226-B
Breugnot, 1991, Calcium antagonists prevent monocyte and endothelial cell-induced modification of low density lipoproteins, Free Rad. Res. Comm., 15, 91, 10.3109/10715769109049129
Dimitrov, 1991, Plasma tocopherol concentrations in response to supplemental vitamin E1–3, Am. J. Clin. Nutr., 53, 723, 10.1093/ajcn/53.3.723
Jialal, 1991, Beta-carotene inhibits the oxidative modification of low density lipoprotein, Biochim. Biophys. Acta, 1086, 134, 10.1016/0005-2760(91)90164-D
Jialal, 1991, Preservation of the endogenous antioxidants in low density lipoprotein by ascorbate but not probucol during oxidative modification, J. Clin. Invest., 87, 597, 10.1172/JCI115035
Kok, 1991, Do antioxidants and polyunsaturated fatty acids have a combined association with coronary atherosclerosis, Atherosclerosis, 31, 85, 10.1016/0021-9150(91)90101-8
Chojkier, 1989, Stimulation of collagen gene expression by ascorbic acid in cultured human fibroblasts, J. Biol. Chem., 264, 16957, 10.1016/S0021-9258(19)84800-7
Houglum, 1991, d-α-Tocopherol inhibits collagen α1 (I) gene expression in cultured human fibroblasts, J. Clin. Invest., 87, 2230, 10.1172/JCI115258
Akeson, 1991, Inhibition of IL-1β expression in THP-1 cells by probucol and tocopherol, Atherosclerosis, 86, 261, 10.1016/0021-9150(91)90222-O
Wiklund, 1991, Uptake and degradation of low density lipoproteins in atherosclerotic rabbit aorta: Role of local LDL modification, J. Lipid Res., 32, 55, 10.1016/S0022-2275(20)42243-6
Frei, 1991, Gas phase oxidants of cigarette smoke induce lipid peroxidation and changes in lipoprotein properties in human blood plasma, Biochem. J., 277, 133, 10.1042/bj2770133
Yokode, 1988, Cholesteryl ester accumulation in macrophages incubated with low density lipoprotein pretreated with cigarette smoke extract, 85, 2344
Negre-Salvayre, 1991, Ultraviolet-treated lipoproteins as a model system for the study of the biological effects of lipid peroxides on cultured cells. III. The protective effect of antioxidants (probucol, catechin, vitamin E) against the cytotoxicity of oxidized LDL occurs in two different ways, Biochim. Biophys. Acta, 1096, 291, 10.1016/0925-4439(91)90065-H
Salonen, 1991, Effects of antioxidant supplementation on platelet function: A randomized pair-matched, placebo-controlled, double-blind trial in men with low antioxidant status1−3, Am. J. Clin. Nutr., 53, 1222, 10.1093/ajcn/53.5.1222
Fruchart, 1989, Antioxidant therapy and uptake of human oxidized LDL by macrophages, Ann. NY Acad. Sci., 570, 447, 10.1111/j.1749-6632.1989.tb14953.x
Janero, 1991, Therapeutic potential of vitamin E against myocardial ischemic-reperfusion injury, Free Rad. Biol. Med., 10, 315, 10.1016/0891-5849(91)90038-5
Chow, 1991, Vitamin E and oxidative stress, Free Rad. Biol. Med., 11, 215, 10.1016/0891-5849(91)90174-2
Björkhem, 1991, The antioxidant butylated hydroxytoluene protects against atherosclerosis, Arteriosclerosis and Thrombosis, 11, 15, 10.1161/01.ATV.11.1.15
Hata, 1991, A secondary prevention of cerebrovascular disease with dl-α-tocopheryl nicotinate (α-TN), 22
Steiner, 1991, α-Tocopherol: A potent inhibitor of platelet adhesion, 21
Zhang, 1987, Oxidized low density lipoproteins in smooth muscle cell cultures: Differential effects on prostanoid synthesis and viability, 89
Zhang, 1990, Heterogeneity in lipid peroxides: Cellular arachidonic acid metabolism and DNA synthesis, 255
Zhang, 1990, Effects of oxidized low density lipoproteins on arachidonic acid metabolism in smooth muscle cells, J. Lipid Res., 31, 551, 10.1016/S0022-2275(20)42824-X
Oncley, 1957, A rapid method for the bulk isolation of β-lipoproteins from human plasma, J. Am. Chem. Soc., 79, 4666, 10.1021/ja01574a024
Traber, 1988, Absorption and transport of deuterium-substituted 2R,4′R,8′-α-tocopherol in human lipoproteins, Lipids, 23, 791, 10.1007/BF02536223
McCormick, 1960, Studies on the distribution of tocopherol in human serum lipoproteins, J. Lipid Res., 1, 221, 10.1016/S0022-2275(20)39066-0
Zhang, 1989, Studies on oxidized low density lipoproteins. Controlled oxidation and a prostaglandin artifact, J. Lipid Res., 30, 141, 10.1016/S0022-2275(20)38376-0
Smith, 1970, Sterol metabolism. Part 9 26-hydrocycholesterol levels in the human aorta, Atherosclerosis, 12, 1, 10.1016/0021-9150(70)90078-X
Slater, 1972, The microdissection of large atherosclerotic plaques to give morphologically and topographically defined fractions for analysis. Part 2: studies on “Nile Blue” cells, Atherosclerosis, 15, 57, 10.1016/0021-9150(72)90037-8
Gavino, 1981, Effect of polyunsaturated fatty acids and antioxidants on lipid peroxidation in tissue cultures, J. Lipid Res., 22, 763, 10.1016/S0022-2275(20)37347-8
Lindsey, 1985, Antioxidant effects of tocopherols and their quinones, Lipids, 20, 151, 10.1007/BF02534247
Cornwell, 1975, Development of atheroma and the lipid composition of the deposit, Vol. 1, 445
Cornwell, 1988, Fatty acid metabolism and cell proliferation, 163
Krinsky, 1989, Antioxidant functions of carotenoids, Free Rad. Biol. Med., 7, 617, 10.1016/0891-5849(89)90143-3
Avogaro, 1991, Some questions concerning a small, more electronegative LDL circulating in human plasma, Atherosclerosis, 91, 163, 10.1016/0021-9150(91)90198-C
Simon, 1989, Formation of 15-hydroxyeicosatetraenoic acid (15-HETE) as the predominant eicosanoid in aortas from Watanabe heritable hyperlipidemic and cholesterol-fed rabbits, Atherosclerosis, 75, 31, 10.1016/0021-9150(89)90204-9
Henriksson, 1985, Formation of 15-HETE as a major hydroxyeicosatetraenoic acid in the atherosclerotic vessel wall, Biochim. Biophys. Acta, 834, 272, 10.1016/0005-2760(85)90166-3
Vedie, 1991, Fractionation of charge-modified low density lipoproteins by fast protein liquid chromatography, J. Lipid Res., 32, 1359, 10.1016/S0022-2275(20)41966-2
Balla, 1991, Hemin: A possible physiological mediator of low density lipoprotein oxidation and endothelial injury, Arteriosclerosis and Thrombosis, 11, 1700, 10.1161/01.ATV.11.6.1700